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Items: 1 to 50 of 197

1.

Editorial overview: Musculoskeletal: New therapeutic targets and delivery systems.

Dixon SJ, Chidiac P.

Curr Opin Pharmacol. 2018 Jun;40:ix-xi. doi: 10.1016/j.coph.2018.06.002. No abstract available.

PMID:
29933940
2.

MLKL Requires the Inositol Phosphate Code to Execute Necroptosis.

Dovey CM, Diep J, Clarke BP, Hale AT, McNamara DE, Guo H, Brown NW Jr, Cao JY, Grace CR, Gough PJ, Bertin J, Dixon SJ, Fiedler D, Mocarski ES, Kaiser WJ, Moldoveanu T, York JD, Carette JE.

Mol Cell. 2018 Jun 7;70(5):936-948.e7. doi: 10.1016/j.molcel.2018.05.010. Epub 2018 Jun 7.

PMID:
29883610
3.

Extracellular nucleotides enhance agonist potency at the parathyroid hormone 1 receptor.

Kim BH, Pereverzev A, Zhu S, Tong AOM, Dixon SJ, Chidiac P.

Cell Signal. 2018 Jun;46:103-112. doi: 10.1016/j.cellsig.2018.02.015. Epub 2018 Mar 1.

PMID:
29501726
4.

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

Galluzzi L, Vitale I, Aaronson SA, Abrams JM, Adam D, Agostinis P, Alnemri ES, Altucci L, Amelio I, Andrews DW, Annicchiarico-Petruzzelli M, Antonov AV, Arama E, Baehrecke EH, Barlev NA, Bazan NG, Bernassola F, Bertrand MJM, Bianchi K, Blagosklonny MV, Blomgren K, Borner C, Boya P, Brenner C, Campanella M, Candi E, Carmona-Gutierrez D, Cecconi F, Chan FK, Chandel NS, Cheng EH, Chipuk JE, Cidlowski JA, Ciechanover A, Cohen GM, Conrad M, Cubillos-Ruiz JR, Czabotar PE, D'Angiolella V, Dawson TM, Dawson VL, De Laurenzi V, De Maria R, Debatin KM, DeBerardinis RJ, Deshmukh M, Di Daniele N, Di Virgilio F, Dixit VM, Dixon SJ, Duckett CS, Dynlacht BD, El-Deiry WS, Elrod JW, Fimia GM, Fulda S, García-Sáez AJ, Garg AD, Garrido C, Gavathiotis E, Golstein P, Gottlieb E, Green DR, Greene LA, Gronemeyer H, Gross A, Hajnoczky G, Hardwick JM, Harris IS, Hengartner MO, Hetz C, Ichijo H, Jäättelä M, Joseph B, Jost PJ, Juin PP, Kaiser WJ, Karin M, Kaufmann T, Kepp O, Kimchi A, Kitsis RN, Klionsky DJ, Knight RA, Kumar S, Lee SW, Lemasters JJ, Levine B, Linkermann A, Lipton SA, Lockshin RA, López-Otín C, Lowe SW, Luedde T, Lugli E, MacFarlane M, Madeo F, Malewicz M, Malorni W, Manic G, Marine JC, Martin SJ, Martinou JC, Medema JP, Mehlen P, Meier P, Melino S, Miao EA, Molkentin JD, Moll UM, Muñoz-Pinedo C, Nagata S, Nuñez G, Oberst A, Oren M, Overholtzer M, Pagano M, Panaretakis T, Pasparakis M, Penninger JM, Pereira DM, Pervaiz S, Peter ME, Piacentini M, Pinton P, Prehn JHM, Puthalakath H, Rabinovich GA, Rehm M, Rizzuto R, Rodrigues CMP, Rubinsztein DC, Rudel T, Ryan KM, Sayan E, Scorrano L, Shao F, Shi Y, Silke J, Simon HU, Sistigu A, Stockwell BR, Strasser A, Szabadkai G, Tait SWG, Tang D, Tavernarakis N, Thorburn A, Tsujimoto Y, Turk B, Vanden Berghe T, Vandenabeele P, Vander Heiden MG, Villunger A, Virgin HW, Vousden KH, Vucic D, Wagner EF, Walczak H, Wallach D, Wang Y, Wells JA, Wood W, Yuan J, Zakeri Z, Zhivotovsky B, Zitvogel L, Melino G, Kroemer G.

Cell Death Differ. 2018 Mar;25(3):486-541. doi: 10.1038/s41418-017-0012-4. Epub 2018 Jan 23. Review.

5.

p53 Suppresses Metabolic Stress-Induced Ferroptosis in Cancer Cells.

Tarangelo A, Magtanong L, Bieging-Rolett KT, Li Y, Ye J, Attardi LD, Dixon SJ.

Cell Rep. 2018 Jan 16;22(3):569-575. doi: 10.1016/j.celrep.2017.12.077.

6.

The impact of non-genetic heterogeneity on cancer cell death.

Inde Z, Dixon SJ.

Crit Rev Biochem Mol Biol. 2018 Feb;53(1):99-114. doi: 10.1080/10409238.2017.1412395. Epub 2017 Dec 18.

PMID:
29250983
7.

Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease.

Stockwell BR, Friedmann Angeli JP, Bayir H, Bush AI, Conrad M, Dixon SJ, Fulda S, Gascón S, Hatzios SK, Kagan VE, Noel K, Jiang X, Linkermann A, Murphy ME, Overholtzer M, Oyagi A, Pagnussat GC, Park J, Ran Q, Rosenfeld CS, Salnikow K, Tang D, Torti FM, Torti SV, Toyokuni S, Woerpel KA, Zhang DD.

Cell. 2017 Oct 5;171(2):273-285. doi: 10.1016/j.cell.2017.09.021. Review.

PMID:
28985560
8.

Mechanically-competent and cytocompatible polycaprolactone-borophosphosilicate hybrid biomaterials.

Mondal D, Dixon SJ, Mequanint K, Rizkalla AS.

J Mech Behav Biomed Mater. 2017 Nov;75:180-189. doi: 10.1016/j.jmbbm.2017.07.010. Epub 2017 Jul 5.

PMID:
28735148
9.

Ferroptosis-like death in plant cells.

Conlon M, Dixon SJ.

Mol Cell Oncol. 2017 Mar 10;4(3):e1302906. doi: 10.1080/23723556.2017.1302906. eCollection 2017.

10.

Systematic Quantification of Population Cell Death Kinetics in Mammalian Cells.

Forcina GC, Conlon M, Wells A, Cao JY, Dixon SJ.

Cell Syst. 2017 Jun 28;4(6):600-610.e6. doi: 10.1016/j.cels.2017.05.002. Epub 2017 Jun 7.

11.

Ferroptosis: bug or feature?

Dixon SJ.

Immunol Rev. 2017 May;277(1):150-157. doi: 10.1111/imr.12533. Review.

PMID:
28462529
12.

Whole-body vibration of mice induces progressive degeneration of intervertebral discs associated with increased expression of Il-1β and multiple matrix degrading enzymes.

McCann MR, Veras MA, Yeung C, Lalli G, Patel P, Leitch KM, Holdsworth DW, Dixon SJ, Séguin CA.

Osteoarthritis Cartilage. 2017 May;25(5):779-789. doi: 10.1016/j.joca.2017.01.004. Epub 2017 Jan 16.

13.

Heat stress induces ferroptosis-like cell death in plants.

Distéfano AM, Martin MV, Córdoba JP, Bellido AM, D'Ippólito S, Colman SL, Soto D, Roldán JA, Bartoli CG, Zabaleta EJ, Fiol DF, Stockwell BR, Dixon SJ, Pagnussat GC.

J Cell Biol. 2017 Feb;216(2):463-476. doi: 10.1083/jcb.201605110. Epub 2017 Jan 18.

14.

Interaction of primary human trabecular meshwork cells with metal alloy candidates for microinvasive glaucoma surgery.

Wang WW, Watson KA, Dixon SJ, Liu H, Rizkalla AS, Hutnik CM.

Clin Exp Ophthalmol. 2017 Jul;45(5):520-528. doi: 10.1111/ceo.12911. Epub 2017 Feb 3.

PMID:
28013525
15.

A Comparison of the Mechanical Measures Used for Assessing Orthodontic Mini-Implant Stability.

Hosein YK, Dixon SJ, Rizkalla AS, Tassi A.

Implant Dent. 2017 Apr;26(2):225-231. doi: 10.1097/ID.0000000000000514.

PMID:
27918313
16.

Whole-body vibration of mice induces articular cartilage degeneration with minimal changes in subchondral bone.

McCann MR, Yeung C, Pest MA, Ratneswaran A, Pollmann SI, Holdsworth DW, Beier F, Dixon SJ, Séguin CA.

Osteoarthritis Cartilage. 2017 May;25(5):770-778. doi: 10.1016/j.joca.2016.11.001. Epub 2016 Nov 10.

17.

Nanomedicine: An iron age for cancer therapy.

Tarangelo A, Dixon SJ.

Nat Nanotechnol. 2016 Nov;11(11):921-922. doi: 10.1038/nnano.2016.199. Epub 2016 Sep 26. No abstract available.

PMID:
27668797
18.

C57BL/6 mice are resistant to joint degeneration induced by whole-body vibration.

Kerr GJ, McCann MR, Branch JK, Ratneswaran A, Pest MA, Holdsworth DW, Beier F, Dixon SJ, Séguin CA.

Osteoarthritis Cartilage. 2017 Mar;25(3):421-425. doi: 10.1016/j.joca.2016.09.020. Epub 2016 Oct 6.

19.

Practical fabrication of microfluidic platforms for live-cell microscopy.

Lorusso D, Nikolov HN, Milner JS, Ochotny NM, Sims SM, Dixon SJ, Holdsworth DW.

Biomed Microdevices. 2016 Oct;18(5):78. doi: 10.1007/s10544-016-0101-z.

PMID:
27523472
20.

Modeling Interactions among Individual P2 Receptors to Explain Complex Response Patterns over a Wide Range of ATP Concentrations.

Xing S, Grol MW, Grutter PH, Dixon SJ, Komarova SV.

Front Physiol. 2016 Jul 13;7:294. doi: 10.3389/fphys.2016.00294. eCollection 2016.

21.

Research Priorities in the Field of Posttraumatic Pain and Disability: Results of a Transdisciplinary Consensus-Generating Workshop.

Walton DM, Elliott JM, Lee J, Loh E, MacDermid JC, Schabrun S, Siqueira WL, Corneil BD, Aal B, Birmingham T, Brown A, Cooper LK, Dickey JP, Dixon SJ, Fraser DD, Gati JS, Gloor GB, Good G, Holdsworth D, McLean SA, Millard W, Miller J, Sadi J, Seminowicz DA, Shoemaker JK, Siegmund GP, Vertseegh T, Wideman TH.

Pain Res Manag. 2016;2016:1859434. doi: 10.1155/2016/1859434. Epub 2016 Jun 14.

22.

Disruption of biomineralization pathways in spinal tissues of a mouse model of diffuse idiopathic skeletal hyperostosis.

Ii H, Warraich S, Tenn N, Quinonez D, Holdsworth DW, Hammond JR, Dixon SJ, Séguin CA.

Bone. 2016 Sep;90:37-49. doi: 10.1016/j.bone.2016.05.008. Epub 2016 May 27.

PMID:
27237608
23.

P2X7 nucleotide receptor signaling potentiates the Wnt/β-catenin pathway in cells of the osteoblast lineage.

Grol MW, Brooks PJ, Pereverzev A, Dixon SJ.

Purinergic Signal. 2016 Sep;12(3):509-20. doi: 10.1007/s11302-016-9517-4. Epub 2016 May 21.

24.

Global survey of cell death mechanisms reveals metabolic regulation of ferroptosis.

Shimada K, Skouta R, Kaplan A, Yang WS, Hayano M, Dixon SJ, Brown LM, Valenzuela CA, Wolpaw AJ, Stockwell BR.

Nat Chem Biol. 2016 Jul;12(7):497-503. doi: 10.1038/nchembio.2079. Epub 2016 May 9.

25.

Reinforcement of flowable dental composites with titanium dioxide nanotubes.

Dafar MO, Grol MW, Canham PB, Dixon SJ, Rizkalla AS.

Dent Mater. 2016 Jun;32(6):817-26. doi: 10.1016/j.dental.2016.03.022. Epub 2016 Apr 6.

PMID:
27059772
26.

Mechanisms of ferroptosis.

Cao JY, Dixon SJ.

Cell Mol Life Sci. 2016 Jun;73(11-12):2195-209. doi: 10.1007/s00018-016-2194-1. Epub 2016 Apr 5. Review.

27.

Emerging roles for lipids in non-apoptotic cell death.

Magtanong L, Ko PJ, Dixon SJ.

Cell Death Differ. 2016 Jul;23(7):1099-109. doi: 10.1038/cdd.2016.25. Epub 2016 Mar 11. Review.

28.

Quantitative in vivo micro-computed tomography for assessment of age-dependent changes in murine whole-body composition.

Beaucage KL, Pollmann SI, Sims SM, Dixon SJ, Holdsworth DW.

Bone Rep. 2016 Apr 9;5:70-80. doi: 10.1016/j.bonr.2016.04.002. eCollection 2016 Dec.

29.

Research priorities in the field of post-traumatic pain and disability: Results of a transdisciplinary consensus-generating workshop.

Walton DM, Elliott J, Lee J, Loh E, MacDermid J, Schabrun S, Siqueira WL, Corneil BD, Aal B, Birmingham T, Brown A, Cooper L, Dickey JP, Dixon SJ, Fraser D, Gati J, Gloor G, Good G, Holdsworth D, McLean SA, Millard W, Miller J, Sadi J, Seminowicz DA, Shoemaker JK, Siegmund G, Versteegh T, Wideman TH.

Pain Res Manag. 2015 Nov 19. pii: 17143. [Epub ahead of print] No abstract available.

PMID:
26583461
30.

Connectivity Homology Enables Inter-Species Network Models of Synthetic Lethality.

Jacunski A, Dixon SJ, Tatonetti NP.

PLoS Comput Biol. 2015 Oct 9;11(10):e1004506. doi: 10.1371/journal.pcbi.1004506. eCollection 2015 Oct.

31.

Boot-insole effects on comfort and plantar loading at the heel and fifth metatarsal during running and turning in soccer.

Nunns MP, Dixon SJ, Clarke J, Carré M.

J Sports Sci. 2016;34(8):730-7. doi: 10.1080/02640414.2015.1069378. Epub 2015 Jul 22.

PMID:
26197986
32.

Reduced oxygen cost of running is related to alignment of the resultant GRF and leg axis vector: A pilot study.

Moore IS, Jones AM, Dixon SJ.

Scand J Med Sci Sports. 2016 Jul;26(7):809-15. doi: 10.1111/sms.12514. Epub 2015 Jul 6.

PMID:
26148145
33.

Human Haploid Cell Genetics Reveals Roles for Lipid Metabolism Genes in Nonapoptotic Cell Death.

Dixon SJ, Winter GE, Musavi LS, Lee ED, Snijder B, Rebsamen M, Superti-Furga G, Stockwell BR.

ACS Chem Biol. 2015 Jul 17;10(7):1604-9. doi: 10.1021/acschembio.5b00245. Epub 2015 May 15.

34.

Repeated exposure to high-frequency low-amplitude vibration induces degeneration of murine intervertebral discs and knee joints.

McCann MR, Patel P, Pest MA, Ratneswaran A, Lalli G, Beaucage KL, Backler GB, Kamphuis MP, Esmail Z, Lee J, Barbalinardo M, Mort JS, Holdsworth DW, Beier F, Dixon SJ, Séguin CA.

Arthritis Rheumatol. 2015 May;67(8):2164-75. doi: 10.1002/art.39154.

35.

Dye distance mapping using waveguide evanescent field fluorescence microscopy and its application to cell biology.

Fleissner F, Morawitz M, Dixon SJ, Langbein U, Mittler S.

J Biophotonics. 2015 Oct;8(10):826-37. doi: 10.1002/jbio.201400088. Epub 2014 Nov 17.

PMID:
25401699
36.

Changes in sagittal plane kinematics with treadmill familiarization to barefoot running.

Moore IS, Dixon SJ.

J Appl Biomech. 2014 Oct;30(5):626-31. doi: 10.1123/jab.2013-0239. Epub 2014 Jul 9.

PMID:
25010043
37.

Pharmacological inhibition of cystine-glutamate exchange induces endoplasmic reticulum stress and ferroptosis.

Dixon SJ, Patel DN, Welsch M, Skouta R, Lee ED, Hayano M, Thomas AG, Gleason CE, Tatonetti NP, Slusher BS, Stockwell BR.

Elife. 2014 May 20;3:e02523. doi: 10.7554/eLife.02523.

38.

Ferrostatins inhibit oxidative lipid damage and cell death in diverse disease models.

Skouta R, Dixon SJ, Wang J, Dunn DE, Orman M, Shimada K, Rosenberg PA, Lo DC, Weinberg JM, Linkermann A, Stockwell BR.

J Am Chem Soc. 2014 Mar 26;136(12):4551-6. doi: 10.1021/ja411006a. Epub 2014 Mar 14.

39.

The role of iron and reactive oxygen species in cell death.

Dixon SJ, Stockwell BR.

Nat Chem Biol. 2014 Jan;10(1):9-17. doi: 10.1038/nchembio.1416. Review.

PMID:
24346035
40.

Loss of P2X7 nucleotide receptor function leads to abnormal fat distribution in mice.

Beaucage KL, Xiao A, Pollmann SI, Grol MW, Beach RJ, Holdsworth DW, Sims SM, Darling MR, Dixon SJ.

Purinergic Signal. 2014;10(2):291-304. doi: 10.1007/s11302-013-9388-x. Epub 2013 Nov 13.

41.

Relationship between metabolic cost and muscular coactivation across running speeds.

Moore IS, Jones AM, Dixon SJ.

J Sci Med Sport. 2014 Nov;17(6):671-6. doi: 10.1016/j.jsams.2013.09.014. Epub 2013 Oct 18.

PMID:
24210693
42.

Effects of isoform-selective phosphatidylinositol 3-kinase inhibitors on osteoclasts: actions on cytoskeletal organization, survival, and resorption.

Shugg RP, Thomson A, Tanabe N, Kashishian A, Steiner BH, Puri KD, Pereverzev A, Lannutti BJ, Jirik FR, Dixon SJ, Sims SM.

J Biol Chem. 2013 Dec 6;288(49):35346-57. doi: 10.1074/jbc.M113.507525. Epub 2013 Oct 16.

43.

Subcellular elevation of cytosolic free calcium is required for osteoclast migration.

Wheal BD, Beach RJ, Tanabe N, Dixon SJ, Sims SM.

J Bone Miner Res. 2014 Mar;29(3):725-34. doi: 10.1002/jbmr.2068.

44.

The differential regulation of osteoblast and osteoclast activity by surface topography of hydroxyapatite coatings.

Costa DO, Prowse PD, Chrones T, Sims SM, Hamilton DW, Rizkalla AS, Dixon SJ.

Biomaterials. 2013 Oct;34(30):7215-26. doi: 10.1016/j.biomaterials.2013.06.014. Epub 2013 Jul 2.

PMID:
23830579
45.

P2 receptor networks regulate signaling duration over a wide dynamic range of ATP concentrations.

Grol MW, Pereverzev A, Sims SM, Dixon SJ.

J Cell Sci. 2013 Aug 15;126(Pt 16):3615-26. doi: 10.1242/jcs.122705. Epub 2013 Jun 7.

46.

Receptor-independent effects of 2'(3')-O-(4-benzoylbenzoyl)ATP triethylammonium salt on cytosolic pH.

Reyes JP, Grol MW, Sims SM, Dixon SJ.

Purinergic Signal. 2013 Dec;9(4):687-93. doi: 10.1007/s11302-013-9365-4. Epub 2013 May 22.

47.

Acute vibration induces transient expression of anabolic genes in the murine intervertebral disc.

McCann MR, Patel P, Beaucage KL, Xiao Y, Bacher C, Siqueira WL, Holdsworth DW, Dixon SJ, Séguin CA.

Arthritis Rheum. 2013 Jul;65(7):1853-64. doi: 10.1002/art.37979.

48.

Synthesis of bioactive and machinable miserite glass-ceramics for dental implant applications.

Saadaldin SA, Dixon SJ, Costa DO, Rizkalla AS.

Dent Mater. 2013 Jun;29(6):645-55. doi: 10.1016/j.dental.2013.03.013. Epub 2013 Apr 12.

PMID:
23587360
49.

Loss of equilibrative nucleoside transporter 1 in mice leads to progressive ectopic mineralization of spinal tissues resembling diffuse idiopathic skeletal hyperostosis in humans.

Warraich S, Bone DB, Quinonez D, Ii H, Choi DS, Holdsworth DW, Drangova M, Dixon SJ, Séguin CA, Hammond JR.

J Bone Miner Res. 2013 May;28(5):1135-49. doi: 10.1002/jbmr.1826.

50.

Monocytes from patients with osteoarthritis display increased osteoclastogenesis and bone resorption: the In Vitro Osteoclast Differentiation in Arthritis study.

Durand M, Komarova SV, Bhargava A, Trebec-Reynolds DP, Li K, Fiorino C, Maria O, Nabavi N, Manolson MF, Harrison RE, Dixon SJ, Sims SM, Mizianty MJ, Kurgan L, Haroun S, Boire G, de Fatima Lucena-Fernandes M, de Brum-Fernandes AJ.

Arthritis Rheum. 2013 Jan;65(1):148-58. doi: 10.1002/art.37722.

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