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Items: 1 to 50 of 209

1.

Prominin2 Drives Ferroptosis Resistance by Stimulating Iron Export.

Brown CW, Amante JJ, Chhoy P, Elaimy AL, Liu H, Zhu LJ, Baer CE, Dixon SJ, Mercurio AM.

Dev Cell. 2019 Dec 2;51(5):575-586.e4. doi: 10.1016/j.devcel.2019.10.007. Epub 2019 Nov 14.

PMID:
31735663
2.

Vibration of osteoblastic cells using a novel motion-control platform does not acutely alter cytosolic calcium, but desensitizes subsequent responses to extracellular ATP.

Lorusso D, Nikolov HN, Holdsworth DW, Dixon SJ.

J Cell Physiol. 2019 Nov 6. doi: 10.1002/jcp.29378. [Epub ahead of print]

PMID:
31696507
3.

The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis.

Bersuker K, Hendricks JM, Li Z, Magtanong L, Ford B, Tang PH, Roberts MA, Tong B, Maimone TJ, Zoncu R, Bassik MC, Nomura DK, Dixon SJ, Olzmann JA.

Nature. 2019 Nov;575(7784):688-692. doi: 10.1038/s41586-019-1705-2. Epub 2019 Oct 21.

PMID:
31634900
4.

A ZDHHC5-GOLGA7 Protein Acyltransferase Complex Promotes Nonapoptotic Cell Death.

Ko PJ, Woodrow C, Dubreuil MM, Martin BR, Skouta R, Bassik MC, Dixon SJ.

Cell Chem Biol. 2019 Oct 17. pii: S2451-9456(19)30319-8. doi: 10.1016/j.chembiol.2019.09.014. [Epub ahead of print]

PMID:
31631010
5.

Loss of ENT1 increases cell proliferation in the annulus fibrosus of the intervertebral disc.

Veras MA, Tenn NA, Kuljanin M, Lajoie GA, Hammond JR, Dixon SJ, Séguin CA.

J Cell Physiol. 2019 Aug;234(8):13705-13719. doi: 10.1002/jcp.28051. Epub 2019 Jan 11.

PMID:
31010267
6.

GPX4 at the Crossroads of Lipid Homeostasis and Ferroptosis.

Forcina GC, Dixon SJ.

Proteomics. 2019 Sep;19(18):e1800311. doi: 10.1002/pmic.201800311. Epub 2019 May 31. Review.

PMID:
30888116
7.

Ferroptosis and Brain Injury.

Magtanong L, Dixon SJ.

Dev Neurosci. 2018;40(5-6):382-395. doi: 10.1159/000496922. Epub 2019 Feb 28. Review.

8.

Ectopic spinal calcification associated with diffuse idiopathic skeletal hyperostosis (DISH): A quantitative micro-ct analysis.

Fournier DE, Norley CJD, Pollmann SI, Bailey CS, Al Helal F, Willmore KE, Holdsworth DW, Dixon SJ, Séguin CA.

J Orthop Res. 2019 Mar;37(3):717-726. doi: 10.1002/jor.24247. Epub 2019 Feb 28.

PMID:
30756413
9.

A Genome-wide Haploid Genetic Screen Identifies Regulators of Glutathione Abundance and Ferroptosis Sensitivity.

Cao JY, Poddar A, Magtanong L, Lumb JH, Mileur TR, Reid MA, Dovey CM, Wang J, Locasale JW, Stone E, Cole SPC, Carette JE, Dixon SJ.

Cell Rep. 2019 Feb 5;26(6):1544-1556.e8. doi: 10.1016/j.celrep.2019.01.043.

10.

Exogenous Monounsaturated Fatty Acids Promote a Ferroptosis-Resistant Cell State.

Magtanong L, Ko PJ, To M, Cao JY, Forcina GC, Tarangelo A, Ward CC, Cho K, Patti GJ, Nomura DK, Olzmann JA, Dixon SJ.

Cell Chem Biol. 2019 Mar 21;26(3):420-432.e9. doi: 10.1016/j.chembiol.2018.11.016. Epub 2019 Jan 24.

PMID:
30686757
11.

A novel technique for measurement of orthodontic mini-implant stability using the Osstell ISQ device.

Hosein YK, Dixon SJ, Rizkalla AS, Tassi A.

Angle Orthod. 2019 Mar;89(2):284-291. doi: 10.2319/011518-46.1. Epub 2018 Nov 1.

PMID:
30382751
12.

Protein palmitoylation and cancer.

Ko PJ, Dixon SJ.

EMBO Rep. 2018 Oct;19(10). pii: e46666. doi: 10.15252/embr.201846666. Epub 2018 Sep 19. Review.

13.

Editorial overview: Musculoskeletal: New therapeutic targets and delivery systems.

Dixon SJ, Chidiac P.

Curr Opin Pharmacol. 2018 Jun;40:ix-xi. doi: 10.1016/j.coph.2018.06.002. No abstract available.

PMID:
29933940
14.

MLKL Requires the Inositol Phosphate Code to Execute Necroptosis.

Dovey CM, Diep J, Clarke BP, Hale AT, McNamara DE, Guo H, Brown NW Jr, Cao JY, Grace CR, Gough PJ, Bertin J, Dixon SJ, Fiedler D, Mocarski ES, Kaiser WJ, Moldoveanu T, York JD, Carette JE.

Mol Cell. 2018 Jun 7;70(5):936-948.e7. doi: 10.1016/j.molcel.2018.05.010. Epub 2018 Jun 7.

15.

Extracellular nucleotides enhance agonist potency at the parathyroid hormone 1 receptor.

Kim BH, Pereverzev A, Zhu S, Tong AOM, Dixon SJ, Chidiac P.

Cell Signal. 2018 Jun;46:103-112. doi: 10.1016/j.cellsig.2018.02.015. Epub 2018 Mar 1.

PMID:
29501726
16.

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

Galluzzi L, Vitale I, Aaronson SA, Abrams JM, Adam D, Agostinis P, Alnemri ES, Altucci L, Amelio I, Andrews DW, Annicchiarico-Petruzzelli M, Antonov AV, Arama E, Baehrecke EH, Barlev NA, Bazan NG, Bernassola F, Bertrand MJM, Bianchi K, Blagosklonny MV, Blomgren K, Borner C, Boya P, Brenner C, Campanella M, Candi E, Carmona-Gutierrez D, Cecconi F, Chan FK, Chandel NS, Cheng EH, Chipuk JE, Cidlowski JA, Ciechanover A, Cohen GM, Conrad M, Cubillos-Ruiz JR, Czabotar PE, D'Angiolella V, Dawson TM, Dawson VL, De Laurenzi V, De Maria R, Debatin KM, DeBerardinis RJ, Deshmukh M, Di Daniele N, Di Virgilio F, Dixit VM, Dixon SJ, Duckett CS, Dynlacht BD, El-Deiry WS, Elrod JW, Fimia GM, Fulda S, García-Sáez AJ, Garg AD, Garrido C, Gavathiotis E, Golstein P, Gottlieb E, Green DR, Greene LA, Gronemeyer H, Gross A, Hajnoczky G, Hardwick JM, Harris IS, Hengartner MO, Hetz C, Ichijo H, Jäättelä M, Joseph B, Jost PJ, Juin PP, Kaiser WJ, Karin M, Kaufmann T, Kepp O, Kimchi A, Kitsis RN, Klionsky DJ, Knight RA, Kumar S, Lee SW, Lemasters JJ, Levine B, Linkermann A, Lipton SA, Lockshin RA, López-Otín C, Lowe SW, Luedde T, Lugli E, MacFarlane M, Madeo F, Malewicz M, Malorni W, Manic G, Marine JC, Martin SJ, Martinou JC, Medema JP, Mehlen P, Meier P, Melino S, Miao EA, Molkentin JD, Moll UM, Muñoz-Pinedo C, Nagata S, Nuñez G, Oberst A, Oren M, Overholtzer M, Pagano M, Panaretakis T, Pasparakis M, Penninger JM, Pereira DM, Pervaiz S, Peter ME, Piacentini M, Pinton P, Prehn JHM, Puthalakath H, Rabinovich GA, Rehm M, Rizzuto R, Rodrigues CMP, Rubinsztein DC, Rudel T, Ryan KM, Sayan E, Scorrano L, Shao F, Shi Y, Silke J, Simon HU, Sistigu A, Stockwell BR, Strasser A, Szabadkai G, Tait SWG, Tang D, Tavernarakis N, Thorburn A, Tsujimoto Y, Turk B, Vanden Berghe T, Vandenabeele P, Vander Heiden MG, Villunger A, Virgin HW, Vousden KH, Vucic D, Wagner EF, Walczak H, Wallach D, Wang Y, Wells JA, Wood W, Yuan J, Zakeri Z, Zhivotovsky B, Zitvogel L, Melino G, Kroemer G.

Cell Death Differ. 2018 Mar;25(3):486-541. doi: 10.1038/s41418-017-0012-4. Epub 2018 Jan 23. Review.

17.

p53 Suppresses Metabolic Stress-Induced Ferroptosis in Cancer Cells.

Tarangelo A, Magtanong L, Bieging-Rolett KT, Li Y, Ye J, Attardi LD, Dixon SJ.

Cell Rep. 2018 Jan 16;22(3):569-575. doi: 10.1016/j.celrep.2017.12.077.

18.

The impact of non-genetic heterogeneity on cancer cell death.

Inde Z, Dixon SJ.

Crit Rev Biochem Mol Biol. 2018 Feb;53(1):99-114. doi: 10.1080/10409238.2017.1412395. Epub 2017 Dec 18. Review.

19.

Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease.

Stockwell BR, Friedmann Angeli JP, Bayir H, Bush AI, Conrad M, Dixon SJ, Fulda S, Gascón S, Hatzios SK, Kagan VE, Noel K, Jiang X, Linkermann A, Murphy ME, Overholtzer M, Oyagi A, Pagnussat GC, Park J, Ran Q, Rosenfeld CS, Salnikow K, Tang D, Torti FM, Torti SV, Toyokuni S, Woerpel KA, Zhang DD.

Cell. 2017 Oct 5;171(2):273-285. doi: 10.1016/j.cell.2017.09.021. Review.

20.

Mechanically-competent and cytocompatible polycaprolactone-borophosphosilicate hybrid biomaterials.

Mondal D, Dixon SJ, Mequanint K, Rizkalla AS.

J Mech Behav Biomed Mater. 2017 Nov;75:180-189. doi: 10.1016/j.jmbbm.2017.07.010. Epub 2017 Jul 5.

PMID:
28735148
21.

Ferroptosis-like death in plant cells.

Conlon M, Dixon SJ.

Mol Cell Oncol. 2017 Mar 10;4(3):e1302906. doi: 10.1080/23723556.2017.1302906. eCollection 2017.

22.

Systematic Quantification of Population Cell Death Kinetics in Mammalian Cells.

Forcina GC, Conlon M, Wells A, Cao JY, Dixon SJ.

Cell Syst. 2017 Jun 28;4(6):600-610.e6. doi: 10.1016/j.cels.2017.05.002. Epub 2017 Jun 7.

23.

Ferroptosis: bug or feature?

Dixon SJ.

Immunol Rev. 2017 May;277(1):150-157. doi: 10.1111/imr.12533. Review.

PMID:
28462529
24.

Whole-body vibration of mice induces progressive degeneration of intervertebral discs associated with increased expression of Il-1β and multiple matrix degrading enzymes.

McCann MR, Veras MA, Yeung C, Lalli G, Patel P, Leitch KM, Holdsworth DW, Dixon SJ, Séguin CA.

Osteoarthritis Cartilage. 2017 May;25(5):779-789. doi: 10.1016/j.joca.2017.01.004. Epub 2017 Jan 16.

25.

Heat stress induces ferroptosis-like cell death in plants.

Distéfano AM, Martin MV, Córdoba JP, Bellido AM, D'Ippólito S, Colman SL, Soto D, Roldán JA, Bartoli CG, Zabaleta EJ, Fiol DF, Stockwell BR, Dixon SJ, Pagnussat GC.

J Cell Biol. 2017 Feb;216(2):463-476. doi: 10.1083/jcb.201605110. Epub 2017 Jan 18.

26.

Interaction of primary human trabecular meshwork cells with metal alloy candidates for microinvasive glaucoma surgery.

Wang WW, Watson KA, Dixon SJ, Liu H, Rizkalla AS, Hutnik CM.

Clin Exp Ophthalmol. 2017 Jul;45(5):520-528. doi: 10.1111/ceo.12911. Epub 2017 Feb 3.

PMID:
28013525
27.

A Comparison of the Mechanical Measures Used for Assessing Orthodontic Mini-Implant Stability.

Hosein YK, Dixon SJ, Rizkalla AS, Tassi A.

Implant Dent. 2017 Apr;26(2):225-231. doi: 10.1097/ID.0000000000000514.

PMID:
27918313
28.

Whole-body vibration of mice induces articular cartilage degeneration with minimal changes in subchondral bone.

McCann MR, Yeung C, Pest MA, Ratneswaran A, Pollmann SI, Holdsworth DW, Beier F, Dixon SJ, Séguin CA.

Osteoarthritis Cartilage. 2017 May;25(5):770-778. doi: 10.1016/j.joca.2016.11.001. Epub 2016 Nov 10.

29.

Nanomedicine: An iron age for cancer therapy.

Tarangelo A, Dixon SJ.

Nat Nanotechnol. 2016 Nov;11(11):921-922. doi: 10.1038/nnano.2016.199. Epub 2016 Sep 26. No abstract available.

30.

C57BL/6 mice are resistant to joint degeneration induced by whole-body vibration.

Kerr GJ, McCann MR, Branch JK, Ratneswaran A, Pest MA, Holdsworth DW, Beier F, Dixon SJ, Séguin CA.

Osteoarthritis Cartilage. 2017 Mar;25(3):421-425. doi: 10.1016/j.joca.2016.09.020. Epub 2016 Oct 6.

31.

Practical fabrication of microfluidic platforms for live-cell microscopy.

Lorusso D, Nikolov HN, Milner JS, Ochotny NM, Sims SM, Dixon SJ, Holdsworth DW.

Biomed Microdevices. 2016 Oct;18(5):78. doi: 10.1007/s10544-016-0101-z.

PMID:
27523472
32.

Modeling Interactions among Individual P2 Receptors to Explain Complex Response Patterns over a Wide Range of ATP Concentrations.

Xing S, Grol MW, Grutter PH, Dixon SJ, Komarova SV.

Front Physiol. 2016 Jul 13;7:294. doi: 10.3389/fphys.2016.00294. eCollection 2016.

33.

Research Priorities in the Field of Posttraumatic Pain and Disability: Results of a Transdisciplinary Consensus-Generating Workshop.

Walton DM, Elliott JM, Lee J, Loh E, MacDermid JC, Schabrun S, Siqueira WL, Corneil BD, Aal B, Birmingham T, Brown A, Cooper LK, Dickey JP, Dixon SJ, Fraser DD, Gati JS, Gloor GB, Good G, Holdsworth D, McLean SA, Millard W, Miller J, Sadi J, Seminowicz DA, Shoemaker JK, Siegmund GP, Vertseegh T, Wideman TH.

Pain Res Manag. 2016;2016:1859434. doi: 10.1155/2016/1859434. Epub 2016 Jun 14.

34.

Disruption of biomineralization pathways in spinal tissues of a mouse model of diffuse idiopathic skeletal hyperostosis.

Ii H, Warraich S, Tenn N, Quinonez D, Holdsworth DW, Hammond JR, Dixon SJ, Séguin CA.

Bone. 2016 Sep;90:37-49. doi: 10.1016/j.bone.2016.05.008. Epub 2016 May 27.

PMID:
27237608
35.

P2X7 nucleotide receptor signaling potentiates the Wnt/β-catenin pathway in cells of the osteoblast lineage.

Grol MW, Brooks PJ, Pereverzev A, Dixon SJ.

Purinergic Signal. 2016 Sep;12(3):509-20. doi: 10.1007/s11302-016-9517-4. Epub 2016 May 21.

36.

Global survey of cell death mechanisms reveals metabolic regulation of ferroptosis.

Shimada K, Skouta R, Kaplan A, Yang WS, Hayano M, Dixon SJ, Brown LM, Valenzuela CA, Wolpaw AJ, Stockwell BR.

Nat Chem Biol. 2016 Jul;12(7):497-503. doi: 10.1038/nchembio.2079. Epub 2016 May 9.

37.

Reinforcement of flowable dental composites with titanium dioxide nanotubes.

Dafar MO, Grol MW, Canham PB, Dixon SJ, Rizkalla AS.

Dent Mater. 2016 Jun;32(6):817-26. doi: 10.1016/j.dental.2016.03.022. Epub 2016 Apr 6.

PMID:
27059772
38.

Mechanisms of ferroptosis.

Cao JY, Dixon SJ.

Cell Mol Life Sci. 2016 Jun;73(11-12):2195-209. doi: 10.1007/s00018-016-2194-1. Epub 2016 Apr 5. Review.

39.

Emerging roles for lipids in non-apoptotic cell death.

Magtanong L, Ko PJ, Dixon SJ.

Cell Death Differ. 2016 Jul;23(7):1099-109. doi: 10.1038/cdd.2016.25. Epub 2016 Mar 11. Review.

40.

Quantitative in vivo micro-computed tomography for assessment of age-dependent changes in murine whole-body composition.

Beaucage KL, Pollmann SI, Sims SM, Dixon SJ, Holdsworth DW.

Bone Rep. 2016 Apr 9;5:70-80. doi: 10.1016/j.bonr.2016.04.002. eCollection 2016 Dec.

41.

Research priorities in the field of post-traumatic pain and disability: Results of a transdisciplinary consensus-generating workshop.

Walton DM, Elliott J, Lee J, Loh E, MacDermid J, Schabrun S, Siqueira WL, Corneil BD, Aal B, Birmingham T, Brown A, Cooper L, Dickey JP, Dixon SJ, Fraser D, Gati J, Gloor G, Good G, Holdsworth D, McLean SA, Millard W, Miller J, Sadi J, Seminowicz DA, Shoemaker JK, Siegmund G, Versteegh T, Wideman TH.

Pain Res Manag. 2015 Nov 19. pii: 17143. [Epub ahead of print] No abstract available.

PMID:
26583461
42.

Connectivity Homology Enables Inter-Species Network Models of Synthetic Lethality.

Jacunski A, Dixon SJ, Tatonetti NP.

PLoS Comput Biol. 2015 Oct 9;11(10):e1004506. doi: 10.1371/journal.pcbi.1004506. eCollection 2015 Oct.

43.

Boot-insole effects on comfort and plantar loading at the heel and fifth metatarsal during running and turning in soccer.

Nunns MP, Dixon SJ, Clarke J, Carré M.

J Sports Sci. 2016;34(8):730-7. doi: 10.1080/02640414.2015.1069378. Epub 2015 Jul 22.

44.

Reduced oxygen cost of running is related to alignment of the resultant GRF and leg axis vector: A pilot study.

Moore IS, Jones AM, Dixon SJ.

Scand J Med Sci Sports. 2016 Jul;26(7):809-15. doi: 10.1111/sms.12514. Epub 2015 Jul 6.

PMID:
26148145
45.

Human Haploid Cell Genetics Reveals Roles for Lipid Metabolism Genes in Nonapoptotic Cell Death.

Dixon SJ, Winter GE, Musavi LS, Lee ED, Snijder B, Rebsamen M, Superti-Furga G, Stockwell BR.

ACS Chem Biol. 2015 Jul 17;10(7):1604-9. doi: 10.1021/acschembio.5b00245. Epub 2015 May 15.

46.

Repeated exposure to high-frequency low-amplitude vibration induces degeneration of murine intervertebral discs and knee joints.

McCann MR, Patel P, Pest MA, Ratneswaran A, Lalli G, Beaucage KL, Backler GB, Kamphuis MP, Esmail Z, Lee J, Barbalinardo M, Mort JS, Holdsworth DW, Beier F, Dixon SJ, Séguin CA.

Arthritis Rheumatol. 2015 May;67(8):2164-75. doi: 10.1002/art.39154.

47.

Dye distance mapping using waveguide evanescent field fluorescence microscopy and its application to cell biology.

Fleissner F, Morawitz M, Dixon SJ, Langbein U, Mittler S.

J Biophotonics. 2015 Oct;8(10):826-37. doi: 10.1002/jbio.201400088. Epub 2014 Nov 17.

PMID:
25401699
48.

Changes in sagittal plane kinematics with treadmill familiarization to barefoot running.

Moore IS, Dixon SJ.

J Appl Biomech. 2014 Oct;30(5):626-31. doi: 10.1123/jab.2013-0239. Epub 2014 Jul 9.

PMID:
25010043
49.

Pharmacological inhibition of cystine-glutamate exchange induces endoplasmic reticulum stress and ferroptosis.

Dixon SJ, Patel DN, Welsch M, Skouta R, Lee ED, Hayano M, Thomas AG, Gleason CE, Tatonetti NP, Slusher BS, Stockwell BR.

Elife. 2014 May 20;3:e02523. doi: 10.7554/eLife.02523.

50.

Ferrostatins inhibit oxidative lipid damage and cell death in diverse disease models.

Skouta R, Dixon SJ, Wang J, Dunn DE, Orman M, Shimada K, Rosenberg PA, Lo DC, Weinberg JM, Linkermann A, Stockwell BR.

J Am Chem Soc. 2014 Mar 26;136(12):4551-6. doi: 10.1021/ja411006a. Epub 2014 Mar 14.

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