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Items: 1 to 50 of 233

1.

Overlapping and discrete aspects of the pathology and pathogenesis of the emerging human pathogenic coronaviruses SARS-CoV, MERS-CoV, and 2019-nCoV.

Liu J, Zheng X, Tong Q, Li W, Wang B, Sutter K, Trilling M, Lu M, Dittmer U, Yang D.

J Med Virol. 2020 Feb 13. doi: 10.1002/jmv.25709. [Epub ahead of print] Review.

PMID:
32056249
2.

SERINC5 Is an Unconventional HIV Restriction Factor That Is Upregulated during Myeloid Cell Differentiation.

Zutz A, Schölz C, Schneider S, Pierini V, Münchhoff M, Sutter K, Wittmann G, Dittmer U, Draenert R, Bogner JR, Fackler OT, Keppler OT.

J Innate Immun. 2020 Jan 14:1-11. doi: 10.1159/000504888. [Epub ahead of print]

3.

HIV infection does not alter interferon α/β receptor 2 expression on mucosal immune cells.

Ickler J, Francois S, Widera M, Santiago ML, Dittmer U, Sutter K.

PLoS One. 2020 Jan 14;15(1):e0218905. doi: 10.1371/journal.pone.0218905. eCollection 2020.

4.

Antiviral potential of human IFN-α subtypes against influenza A H3N2 infection in human lung explants reveals subtype-specific activities.

Matos ADR, Wunderlich K, Schloer S, Schughart K, Geffers R, Seders M, Witt M, Christersson A, Wiewrodt R, Wiebe K, Barth P, Hocke A, Hippenstiel S, Hönzke K, Dittmer U, Sutter K, Rescher U, Rodionycheva S, Matera N, Ludwig S, Brunotte L.

Emerg Microbes Infect. 2019;8(1):1763-1776. doi: 10.1080/22221751.2019.1698271.

5.

Concurrent administration of IFNα14 and cART in TKO-BLT mice enhances suppression of HIV-1 viremia but does not eliminate the latent reservoir.

Sutter K, Lavender KJ, Messer RJ, Widera M, Williams K, Race B, Hasenkrug KJ, Dittmer U.

Sci Rep. 2019 Dec 2;9(1):18089. doi: 10.1038/s41598-019-54650-9.

6.

TLR2 Stimulation Increases Cellular Metabolism in CD8+ T Cells and Thereby Enhances CD8+ T Cell Activation, Function, and Antiviral Activity.

Zhang E, Ma Z, Li Q, Yan H, Liu J, Wu W, Guo J, Zhang X, Kirschning CJ, Xu H, Lang PA, Yang D, Dittmer U, Yan H, Lu M.

J Immunol. 2019 Dec 1;203(11):2872-2886. doi: 10.4049/jimmunol.1900065. Epub 2019 Oct 21.

PMID:
31636238
7.

Diverse Immunomodulatory Effects of Individual IFNα Subtypes on Virus-Specific CD8+ T Cell Responses.

Dickow J, Francois S, Kaiserling RL, Malyshkina A, Drexler I, Westendorf AM, Lang KS, Santiago ML, Dittmer U, Sutter K.

Front Immunol. 2019 Sep 24;10:2255. doi: 10.3389/fimmu.2019.02255. eCollection 2019.

8.

Characterization of Endogenous SERINC5 Protein as Anti-HIV-1 Factor.

Passos V, Zillinger T, Casartelli N, Wachs AS, Xu S, Malassa A, Steppich K, Schilling H, Franz S, Todt D, Steinmann E, Sutter K, Dittmer U, Bohne J, Schwartz O, Barchet W, Goffinet C.

J Virol. 2019 Nov 26;93(24). pii: e01221-19. doi: 10.1128/JVI.01221-19. Print 2019 Dec 15.

9.

Toll-Like Receptor 7 Activation Enhances CD8+ T Cell Effector Functions by Promoting Cellular Glycolysis.

Li Q, Yan Y, Liu J, Huang X, Zhang X, Kirschning C, Xu HC, Lang PA, Dittmer U, Zhang E, Lu M.

Front Immunol. 2019 Sep 12;10:2191. doi: 10.3389/fimmu.2019.02191. eCollection 2019.

10.

Immunization with a murine cytomegalovirus based vector encoding retrovirus envelope confers strong protection from Friend retrovirus challenge infection.

Bongard N, Le-Trilling VTK, Malyshkina A, Rückborn M, Wohlgemuth K, Wensing I, Windmann S, Dittmer U, Trilling M, Bayer W.

PLoS Pathog. 2019 Sep 30;15(9):e1008043. doi: 10.1371/journal.ppat.1008043. eCollection 2019 Sep.

11.

Hybrid green-blue-gray decentralized urban drainage systems design, a simulation-optimization framework.

Bakhshipour AE, Dittmer U, Haghighi A, Nowak W.

J Environ Manage. 2019 Nov 1;249:109364. doi: 10.1016/j.jenvman.2019.109364. Epub 2019 Aug 9.

PMID:
31404854
12.

Measurement of BK-polyomavirus Non-Coding Control Region Driven Transcriptional Activity Via Flow Cytometry.

Korth J, Sertznig H, Moyrer S, Doevelaar AAN, Westhoff TH, Babel N, Witzke O, Kribben A, Dittmer U, Widera M.

J Vis Exp. 2019 Jul 13;(149). doi: 10.3791/59755.

PMID:
31355784
13.

Different Biological Activities of Specific Interferon Alpha Subtypes.

Hasenkrug KJ, Lavender KJ, Santiago ML, Sutter K, Dittmer U.

mSphere. 2019 Jul 24;4(4). pii: e00127-19. doi: 10.1128/mSphere.00127-19. No abstract available.

14.

Activation of the TLR signaling pathway in CD8+ T cells counteracts liver endothelial cell-induced T cell tolerance.

Zhang E, Yan H, Li Q, Dittmer U, Yan H, Lu M.

Cell Mol Immunol. 2019 Sep;16(9):774-776. doi: 10.1038/s41423-019-0255-8. Epub 2019 Jun 26. No abstract available.

PMID:
31243356
15.

IFI16 Targets the Transcription Factor Sp1 to Suppress HIV-1 Transcription and Latency Reactivation.

Hotter D, Bosso M, Jønsson KL, Krapp C, Stürzel CM, Das A, Littwitz-Salomon E, Berkhout B, Russ A, Wittmann S, Gramberg T, Zheng Y, Martins LJ, Planelles V, Jakobsen MR, Hahn BH, Dittmer U, Sauter D, Kirchhoff F.

Cell Host Microbe. 2019 Jun 12;25(6):858-872.e13. doi: 10.1016/j.chom.2019.05.002. Epub 2019 Jun 4.

PMID:
31175045
16.

MMP2/MMP9-mediated CD100 shedding is crucial for inducing intrahepatic anti-HBV CD8 T cell responses and HBV clearance.

Yang S, Wang L, Pan W, Bayer W, Thoens C, Heim K, Dittmer U, Timm J, Wang Q, Yu Q, Luo J, Liu Y, Hofmann M, Thimme R, Zhang X, Chen H, Wang H, Feng X, Yang X, Lu Y, Lu M, Yang D, Liu J.

J Hepatol. 2019 Oct;71(4):685-698. doi: 10.1016/j.jhep.2019.05.013. Epub 2019 Jun 5.

PMID:
31173811
17.

Guanylate-Binding Proteins 2 and 5 Exert Broad Antiviral Activity by Inhibiting Furin-Mediated Processing of Viral Envelope Proteins.

Braun E, Hotter D, Koepke L, Zech F, Groß R, Sparrer KMJ, Müller JA, Pfaller CK, Heusinger E, Wombacher R, Sutter K, Dittmer U, Winkler M, Simmons G, Jakobsen MR, Conzelmann KK, Pöhlmann S, Münch J, Fackler OT, Kirchhoff F, Sauter D.

Cell Rep. 2019 May 14;27(7):2092-2104.e10. doi: 10.1016/j.celrep.2019.04.063.

18.

Friend retrovirus studies reveal complex interactions between intrinsic, innate and adaptive immunity.

Dittmer U, Sutter K, Kassiotis G, Zelinskyy G, Bánki Z, Stoiber H, Santiago ML, Hasenkrug KJ.

FEMS Microbiol Rev. 2019 Sep 1;43(5):435-456. doi: 10.1093/femsre/fuz012.

19.

Plasmacytoid dendritic cells respond to Epstein-Barr virus infection with a distinct type I interferon subtype profile.

Gujer C, Murer A, Müller A, Vanoaica D, Sutter K, Jacque E, Fournier N, Kalchschmidt J, Zbinden A, Capaul R, Dzionek A, Mondon P, Dittmer U, Münz C.

Blood Adv. 2019 Apr 9;3(7):1129-1144. doi: 10.1182/bloodadvances.2018025536.

20.

The PD-1/PD-L1 Pathway Affects the Expansion and Function of Cytotoxic CD8+ T Cells During an Acute Retroviral Infection.

David P, Megger DA, Kaiser T, Werner T, Liu J, Chen L, Sitek B, Dittmer U, Zelinskyy G.

Front Immunol. 2019 Feb 5;10:54. doi: 10.3389/fimmu.2019.00054. eCollection 2019.

21.

Infection of B Cell Follicle-Resident Cells by Friend Retrovirus Occurs during Acute Infection and Is Maintained during Viral Persistence.

Windmann S, Otto L, Hrycak CP, Malyshkina A, Bongard N, David P, Gunzer M, Dittmer U, Bayer W.

mBio. 2019 Feb 19;10(1). pii: e00004-19. doi: 10.1128/mBio.00004-19.

22.

The detection of BKPyV genotypes II and IV after renal transplantation as a simple tool for risk assessment for PyVAN and transplant outcome already at early stages of BKPyV reactivation.

Korth J, Anastasiou OE, Bräsen JH, Brinkhoff A, Lehmann U, Kribben A, Dittmer U, Verheyen J, Wilde B, Ciesek S, Witzke O, Widera M.

J Clin Virol. 2019 Apr;113:14-19. doi: 10.1016/j.jcv.2019.02.002. Epub 2019 Feb 10.

PMID:
30771597
23.

Fcγ Receptor Type I (CD64)-Mediated Impairment of the Capacity of Dendritic Cells to Activate Specific CD8 T Cells by IgG-opsonized Friend Virus.

Bánki Z, Werner R, Riepler L, Rössler A, Müllauer B, Hegen V, Bayer W, Verbeek JS, Dittmer U, Stoiber H.

Viruses. 2019 Feb 8;11(2). pii: E145. doi: 10.3390/v11020145.

24.

Effects of Friend Virus Infection and Regulatory T Cells on the Antigen Presentation Function of B Cells.

Moore TC, Messer RJ, Gonzaga LM, Mather JM, Carmody AB, Bayer W, Littwitz-Salomon E, Dittmer U, Hasenkrug KJ.

mBio. 2019 Jan 22;10(1). pii: e02578-18. doi: 10.1128/mBio.02578-18.

25.

Chronic retroviral infection of mice promotes tumor development, but CD137 agonist therapy restores effective tumor immune surveillance.

Malyshkina A, Littwitz-Salomon E, Sutter K, Ross JA, Paschen A, Windmann S, Schimmer S, Dittmer U.

Cancer Immunol Immunother. 2019 Mar;68(3):479-488. doi: 10.1007/s00262-019-02300-4. Epub 2019 Jan 11.

PMID:
30635687
26.

Induction of herpes simplex virus type 1 cell-to-cell spread inhibiting antibodies by a calcium phosphate nanoparticle-based vaccine.

Kopp M, Aufderhorst UW, Alt M, Dittmer U, Eis-Hübinger AM, Giebel B, Roggendorf M, Epple M, Krawczyk A.

Nanomedicine. 2019 Feb;16:138-148. doi: 10.1016/j.nano.2018.12.002. Epub 2018 Dec 27.

27.

PASylated interferon α efficiently suppresses hepatitis B virus and induces anti-HBs seroconversion in HBV-transgenic mice.

Xia Y, Schlapschy M, Morath V, Roeder N, Vogt EI, Stadler D, Cheng X, Dittmer U, Sutter K, Heikenwalder M, Skerra A, Protzer U.

Antiviral Res. 2019 Jan;161:134-143. doi: 10.1016/j.antiviral.2018.11.003. Epub 2018 Nov 12.

PMID:
30439382
28.

Friend retrovirus infection induces the development of memory-like natural killer cells.

Littwitz-Salomon E, Nguyen T, Schimmer S, Dittmer U.

Retrovirology. 2018 Oct 6;15(1):68. doi: 10.1186/s12977-018-0450-1.

29.

Corrigendum to "Antibody-based immunotherapy of acyclovir resistant ocular herpes simplex virus infection" [Virology 512 (2017) 194-200].

Bauer D, Keller J, Alt M, Schubert A, Aufderhorst UW, Palapys V, Kasper M, Heilingloh CS, Dittmer U, Laffer B, Eis-Hübinger AM, Verjans GM, Heiligenhaus A, Roggendorf M, Krawczyk A.

Virology. 2019 Jan 2;526:231-232. doi: 10.1016/j.virol.2018.09.012. Epub 2018 Oct 2. No abstract available.

30.

Impact of immune suppressive agents on the BK-Polyomavirus non coding control region.

Korth J, Anastasiou OE, Verheyen J, Dickow J, Sertznig H, Frericks N, Bleekmann B, Kribben A, Brinkhoff A, Wilde B, Sutter K, Dittmer U, Ciesek S, Witzke O, Widera M.

Antiviral Res. 2018 Nov;159:68-76. doi: 10.1016/j.antiviral.2018.09.013. Epub 2018 Sep 27.

PMID:
30268912
31.

The Cytotoxic Activity of Natural Killer Cells Is Suppressed by IL-10+ Regulatory T Cells During Acute Retroviral Infection.

Littwitz-Salomon E, Malyshkina A, Schimmer S, Dittmer U.

Front Immunol. 2018 Aug 27;9:1947. doi: 10.3389/fimmu.2018.01947. eCollection 2018.

32.

Evaluation of susceptibility of HIV-1 CRF01_AE variants to neutralization by a panel of broadly neutralizing antibodies.

Wang H, Yuan T, Li T, Li Y, Qian F, Zhu C, Liang S, Hoffmann D, Dittmer U, Sun B, Yang R.

Arch Virol. 2018 Dec;163(12):3303-3315. doi: 10.1007/s00705-018-4011-7. Epub 2018 Sep 8.

PMID:
30196320
33.

Rapid Rebound of a Preexisting CXCR4-tropic Human Immunodeficiency Virus Variant After Allogeneic Transplantation With CCR5 Δ32 Homozygous Stem Cells.

Verheyen J, Thielen A, Lübke N, Dirks M, Widera M, Dittmer U, Kordelas L, Däumer M, de Jong DCM, Wensing AMJ, Kaiser R, Nijhuis M, Esser S.

Clin Infect Dis. 2019 Feb 1;68(4):684-687. doi: 10.1093/cid/ciy565.

PMID:
30020413
34.

CEACAM1 promotes CD8+ T cell responses and improves control of a chronic viral infection.

Khairnar V, Duhan V, Patil AM, Zhou F, Bhat H, Thoens C, Sharma P, Adomati T, Friendrich SK, Bezgovsek J, Dreesen JD, Wennemuth G, Westendorf AM, Zelinskyy G, Dittmer U, Hardt C, Timm J, Göthert JR, Lang PA, Singer BB, Lang KS.

Nat Commun. 2018 Jul 2;9(1):2561. doi: 10.1038/s41467-018-04832-2.

35.

Recent advances in the discovery and development of TLR ligands as novel therapeutics for chronic HBV and HIV infections.

Du K, Liu J, Broering R, Zhang X, Yang D, Dittmer U, Lu M.

Expert Opin Drug Discov. 2018 Jul;13(7):661-670. doi: 10.1080/17460441.2018.1473372. Epub 2018 May 17. Review.

PMID:
29772941
36.

Induction of Type I Interferons by Therapeutic Nanoparticle-Based Vaccination Is Indispensable to Reinforce Cytotoxic CD8+ T Cell Responses During Chronic Retroviral Infection.

Knuschke T, Rotan O, Bayer W, Kollenda S, Dickow J, Sutter K, Hansen W, Dittmer U, Lang KS, Epple M, Buer J, Westendorf AM.

Front Immunol. 2018 Apr 23;9:614. doi: 10.3389/fimmu.2018.00614. eCollection 2018.

37.

Hepatitis B Virus-Specific CD8+ T Cells Maintain Functional Exhaustion after Antigen Reexposure in an Acute Activation Immune Environment.

Wang Q, Pan W, Liu Y, Luo J, Zhu D, Lu Y, Feng X, Yang X, Dittmer U, Lu M, Yang D, Liu J.

Front Immunol. 2018 Feb 12;9:219. doi: 10.3389/fimmu.2018.00219. eCollection 2018.

38.

Interferon α subtypes in HIV infection.

Sutter K, Dickow J, Dittmer U.

Cytokine Growth Factor Rev. 2018 Apr;40:13-18. doi: 10.1016/j.cytogfr.2018.02.002. Epub 2018 Feb 13. Review.

PMID:
29475588
39.

Imaging of cytotoxic antiviral immunity while considering the 3R principle of animal research.

Otto L, Zelinskyy G, Schuster M, Dittmer U, Gunzer M.

J Mol Med (Berl). 2018 Apr;96(3-4):349-360. doi: 10.1007/s00109-018-1628-7. Epub 2018 Feb 19.

PMID:
29460050
40.

Regulatory T cells in retroviral infections.

Hasenkrug KJ, Chougnet CA, Dittmer U.

PLoS Pathog. 2018 Feb 15;14(2):e1006776. doi: 10.1371/journal.ppat.1006776. eCollection 2018 Feb. Review.

41.

Friend virus limits adaptive cellular immune responses by imprinting a maturation-resistant and T helper type 2-biased immunophenotype in dendritic cells.

Shen L, Tenzer S, Hess M, Distler U, Tubbe I, Montermann E, Schimmer S, Dittmer U, Grabbe S, Bros M.

PLoS One. 2018 Feb 9;13(2):e0192541. doi: 10.1371/journal.pone.0192541. eCollection 2018.

42.

Expression Pattern of Individual IFNA Subtypes in Chronic HIV Infection.

Li Y, Sun B, Esser S, Jessen H, Streeck H, Widera M, Yang R, Dittmer U, Sutter K.

J Interferon Cytokine Res. 2017 Dec;37(12):541-549. doi: 10.1089/jir.2017.0076.

PMID:
29252127
43.

Hypoxia-inducible factor 1α is Essential for Macrophage-mediated Erythroblast Proliferation in Acute Friend Retrovirus Infection.

Schreiber T, Quinting T, Dittmer U, Fandrey J, Sutter K.

Sci Rep. 2017 Dec 8;7(1):17236. doi: 10.1038/s41598-017-17324-y.

44.

A Therapeutic Antiviral Antibody Inhibits the Anterograde Directed Neuron-to-Cell Spread of Herpes Simplex Virus and Protects against Ocular Disease.

Bauer D, Alt M, Dirks M, Buch A, Heilingloh CS, Dittmer U, Giebel B, Görgens A, Palapys V, Kasper M, Eis-Hübinger AM, Sodeik B, Heiligenhaus A, Roggendorf M, Krawczyk A.

Front Microbiol. 2017 Oct 31;8:2115. doi: 10.3389/fmicb.2017.02115. eCollection 2017.

45.

Impact of low-level BK polyomavirus viremia on intermediate-term renal allograft function.

Korth J, Widera M, Dolff S, Guberina H, Bienholz A, Brinkhoff A, Anastasiou OE, Kribben A, Dittmer U, Verheyen J, Wilde B, Witzke O.

Transpl Infect Dis. 2018 Feb;20(1). doi: 10.1111/tid.12817. Epub 2018 Jan 16.

PMID:
29156086
46.

An advanced BLT-humanized mouse model for extended HIV-1 cure studies.

Lavender KJ, Pace C, Sutter K, Messer RJ, Pouncey DL, Cummins NW, Natesampillai S, Zheng J, Goldsmith J, Widera M, Van Dis ES, Phillips K, Race B, Dittmer U, Kukolj G, Hasenkrug KJ.

AIDS. 2018 Jan 2;32(1):1-10. doi: 10.1097/QAD.0000000000001674.

47.

Hepatitis B virus sensitivity to interferon-α in hepatocytes is more associated with cellular interferon response than with viral genotype.

Shen F, Li Y, Wang Y, Sozzi V, Revill PA, Liu J, Gao L, Yang G, Lu M, Sutter K, Dittmer U, Chen J, Yuan Z.

Hepatology. 2018 Apr;67(4):1237-1252. doi: 10.1002/hep.29609. Epub 2018 Feb 22.

PMID:
29059468
48.

Cytomegalovirus reactivation in patients with refractory checkpoint inhibitor-induced colitis.

Franklin C, Rooms I, Fiedler M, Reis H, Milsch L, Herz S, Livingstone E, Zimmer L, Schmid KW, Dittmer U, Schadendorf D, Schilling B.

Eur J Cancer. 2017 Nov;86:248-256. doi: 10.1016/j.ejca.2017.09.019. Epub 2017 Oct 19.

PMID:
29055840
49.

Antibody-based immunotherapy of aciclovir resistant ocular herpes simplex virus infections.

Bauer D, Keller J, Alt M, Schubert A, Aufderhorst UW, Palapys V, Kasper M, Heilingloh CS, Dittmer U, Laffer B, Eis-Hübinger AM, Verjans GM, Heiligenhaus A, Roggendorf M, Krawczyk A.

Virology. 2017 Dec;512:194-200. doi: 10.1016/j.virol.2017.09.021. Epub 2017 Oct 3. Erratum in: Virology. 2019 Jan 2;526:231-232.

50.

Differential Inhibitory Receptor Expression on T Cells Delineates Functional Capacities in Chronic Viral Infection.

Teigler JE, Zelinskyy G, Eller MA, Bolton DL, Marovich M, Gordon AD, Alrubayyi A, Alter G, Robb ML, Martin JN, Deeks SG, Michael NL, Dittmer U, Streeck H.

J Virol. 2017 Nov 14;91(23). pii: e01263-17. doi: 10.1128/JVI.01263-17. Print 2017 Dec 1.

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