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Items: 1 to 50 of 83

1.

Deconvolution of transcriptomes and miRNomes by independent component analysis provides insights into biological processes and clinical outcomes of melanoma patients.

Nazarov PV, Wienecke-Baldacchino AK, Zinovyev A, Czerwińska U, Muller A, Nashan D, Dittmar G, Azuaje F, Kreis S.

BMC Med Genomics. 2019 Sep 18;12(1):132. doi: 10.1186/s12920-019-0578-4.

2.

DCAF8, a novel MuRF1 interaction partner, promotes muscle atrophy.

Nowak M, Suenkel B, Porras P, Migotti R, Schmidt F, Kny M, Zhu X, Wanker EE, Dittmar G, Fielitz J, Sommer T.

J Cell Sci. 2019 Sep 6;132(17). pii: jcs233395. doi: 10.1242/jcs.233395.

PMID:
31391242
3.

Assessment of Ubiquitin Chain Topology by Targeted Mass Spectrometry.

Longworth J, Dittmar G.

Methods Mol Biol. 2019;1977:25-34. doi: 10.1007/978-1-4939-9232-4_3.

PMID:
30980320
4.

Hub genes in a pan-cancer co-expression network show potential for predicting drug responses.

Azuaje F, Kaoma T, Jeanty C, Nazarov PV, Muller A, Kim SY, Dittmar G, Golebiewska A, Niclou SP.

Version 2. F1000Res. 2018 Dec 7 [revised 2019 Jan 1];7:1906. doi: 10.12688/f1000research.17149.2. eCollection 2018.

5.

A protein quality control pathway regulated by linear ubiquitination.

van Well EM, Bader V, Patra M, Sánchez-Vicente A, Meschede J, Furthmann N, Schnack C, Blusch A, Longworth J, Petrasch-Parwez E, Mori K, Arzberger T, Trümbach D, Angersbach L, Showkat C, Sehr DA, Berlemann LA, Goldmann P, Clement AM, Behl C, Woerner AC, Saft C, Wurst W, Haass C, Ellrichmann G, Gold R, Dittmar G, Hipp MS, Hartl FU, Tatzelt J, Winklhofer KF.

EMBO J. 2019 May 2;38(9). pii: e100730. doi: 10.15252/embj.2018100730. Epub 2019 Mar 18.

PMID:
30886048
6.

PRISMA: Protein Interaction Screen on Peptide Matrix Reveals Interaction Footprints and Modifications- Dependent Interactome of Intrinsically Disordered C/EBPβ.

Dittmar G, Hernandez DP, Kowenz-Leutz E, Kirchner M, Kahlert G, Wesolowski R, Baum K, Knoblich M, Hofstätter M, Muller A, Wolf J, Reimer U, Leutz A.

iScience. 2019 Mar 29;13:351-370. doi: 10.1016/j.isci.2019.02.026. Epub 2019 Mar 1.

7.

SorCS2 Controls Functional Expression of Amino Acid Transporter EAAT3 and Protects Neurons from Oxidative Stress and Epilepsy-Induced Pathology.

Malik AR, Szydlowska K, Nizinska K, Asaro A, van Vliet EA, Popp O, Dittmar G, Fritsche-Guenther R, Kirwan JA, Nykjaer A, Lukasiuk K, Aronica E, Willnow TE.

Cell Rep. 2019 Mar 5;26(10):2792-2804.e6. doi: 10.1016/j.celrep.2019.02.027.

8.

Unique properties of PTEN-L contribute to neuroprotection in response to ischemic-like stress.

Jochner MCE, An J, Lättig-Tünnemann G, Kirchner M, Dagane A, Dittmar G, Dirnagl U, Eickholt BJ, Harms C.

Sci Rep. 2019 Feb 28;9(1):3183. doi: 10.1038/s41598-019-39438-1.

9.

The lipid head group is the key element for substrate recognition by the P4 ATPase ALA2: a phosphatidylserine flippase.

Theorin L, Faxén K, Sørensen DM, Migotti R, Dittmar G, Schiller J, Daleke DL, Palmgren M, López-Marqués RL, Günther Pomorski T.

Biochem J. 2019 Mar 6;476(5):783-794. doi: 10.1042/BCJ20180891.

10.

Deregulated Splicing Is a Major Mechanism of RNA-Induced Toxicity in Huntington's Disease.

Schilling J, Broemer M, Atanassov I, Duernberger Y, Vorberg I, Dieterich C, Dagane A, Dittmar G, Wanker E, van Roon-Mom W, Winter J, Krauß S.

J Mol Biol. 2019 Apr 19;431(9):1869-1877. doi: 10.1016/j.jmb.2019.01.034. Epub 2019 Jan 31.

11.

The IκB kinase complex is a regulator of mRNA stability.

Mikuda N, Kolesnichenko M, Beaudette P, Popp O, Uyar B, Sun W, Tufan AB, Perder B, Akalin A, Chen W, Mertins P, Dittmar G, Hinz M, Scheidereit C.

EMBO J. 2018 Dec 14;37(24). pii: e98658. doi: 10.15252/embj.201798658. Epub 2018 Nov 22.

PMID:
30467221
12.

S-palmitoylation Is Required for the Control of Growth Cone Morphology of DRG Neurons by CNP-Induced cGMP Signaling.

Dumoulin A, Dagane A, Dittmar G, Rathjen FG.

Front Mol Neurosci. 2018 Sep 24;11:345. doi: 10.3389/fnmol.2018.00345. eCollection 2018.

13.

On the relation between filament density, force generation, and protrusion rate in mesenchymal cell motility.

Dolati S, Kage F, Mueller J, Müsken M, Kirchner M, Dittmar G, Sixt M, Rottner K, Falcke M.

Mol Biol Cell. 2018 Nov 1;29(22):2674-2686. doi: 10.1091/mbc.E18-02-0082. Epub 2018 Aug 29.

14.

Queuosine-modified tRNAs confer nutritional control of protein translation.

Tuorto F, Legrand C, Cirzi C, Federico G, Liebers R, Müller M, Ehrenhofer-Murray AE, Dittmar G, Gröne HJ, Lyko F.

EMBO J. 2018 Sep 14;37(18). pii: e99777. doi: 10.15252/embj.201899777. Epub 2018 Aug 9.

15.

Isolation of native plasma membrane H+-ATPase (Pma1p) in both the active and basal activation states.

Pedersen JT, Kanashova T, Dittmar G, Palmgren M.

FEBS Open Bio. 2018 Mar 25;8(5):774-783. doi: 10.1002/2211-5463.12413. eCollection 2018 May.

16.

Inhibition of the MID1 protein complex: a novel approach targeting APP protein synthesis.

Matthes F, Hettich MM, Schilling J, Flores-Dominguez D, Blank N, Wiglenda T, Buntru A, Wolf H, Weber S, Vorberg I, Dagane A, Dittmar G, Wanker E, Ehninger D, Krauss S.

Cell Death Discov. 2018 Jan 29;4:4. doi: 10.1038/s41420-017-0003-8. eCollection 2018 Dec.

17.

SORCS1 and SORCS3 control energy balance and orexigenic peptide production.

Subkhangulova A, Malik AR, Hermey G, Popp O, Dittmar G, Rathjen T, Poy MN, Stumpf A, Beed PS, Schmitz D, Breiderhoff T, Willnow TE.

EMBO Rep. 2018 Apr;19(4). pii: e44810. doi: 10.15252/embr.201744810. Epub 2018 Feb 12.

18.

Senescence-associated reprogramming promotes cancer stemness.

Milanovic M, Fan DNY, Belenki D, Däbritz JHM, Zhao Z, Yu Y, Dörr JR, Dimitrova L, Lenze D, Monteiro Barbosa IA, Mendoza-Parra MA, Kanashova T, Metzner M, Pardon K, Reimann M, Trumpp A, Dörken B, Zuber J, Gronemeyer H, Hummel M, Dittmar G, Lee S, Schmitt CA.

Nature. 2018 Jan 4;553(7686):96-100. doi: 10.1038/nature25167. Epub 2017 Dec 20.

PMID:
29258294
19.

Purification and characterisation of the yeast plasma membrane ATP binding cassette transporter Pdr11p.

Laub KR, Marek M, Stanchev LD, Herrera SA, Kanashova T, Bourmaud A, Dittmar G, Günther Pomorski T.

PLoS One. 2017 Sep 18;12(9):e0184236. doi: 10.1371/journal.pone.0184236. eCollection 2017.

20.

A map of human circular RNAs in clinically relevant tissues.

Maass PG, Glažar P, Memczak S, Dittmar G, Hollfinger I, Schreyer L, Sauer AV, Toka O, Aiuti A, Luft FC, Rajewsky N.

J Mol Med (Berl). 2017 Nov;95(11):1179-1189. doi: 10.1007/s00109-017-1582-9. Epub 2017 Aug 25.

21.

Tissue Specific Labeling in Proteomics.

Ramberger E, Dittmar G.

Proteomes. 2017 Jul 18;5(3). pii: E17. doi: 10.3390/proteomes5030017. Review.

22.

RNA sequencing and transcriptome arrays analyses show opposing results for alternative splicing in patient derived samples.

Nazarov PV, Muller A, Kaoma T, Nicot N, Maximo C, Birembaut P, Tran NL, Dittmar G, Vallar L.

BMC Genomics. 2017 Jun 6;18(1):443. doi: 10.1186/s12864-017-3819-y.

23.

Quantitative proteomic analysis of Parkin substrates in Drosophila neurons.

Martinez A, Lectez B, Ramirez J, Popp O, Sutherland JD, Urbé S, Dittmar G, Clague MJ, Mayor U.

Mol Neurodegener. 2017 Apr 11;12(1):29. doi: 10.1186/s13024-017-0170-3.

24.

Translation of CircRNAs.

Pamudurti NR, Bartok O, Jens M, Ashwal-Fluss R, Stottmeister C, Ruhe L, Hanan M, Wyler E, Perez-Hernandez D, Ramberger E, Shenzis S, Samson M, Dittmar G, Landthaler M, Chekulaeva M, Rajewsky N, Kadener S.

Mol Cell. 2017 Apr 6;66(1):9-21.e7. doi: 10.1016/j.molcel.2017.02.021. Epub 2017 Mar 23.

25.

Deciphering the Ubiquitin Code.

Dittmar G, Selbach M.

Mol Cell. 2017 Mar 2;65(5):779-780. doi: 10.1016/j.molcel.2017.02.011.

26.

Initiation of acute graft-versus-host disease by angiogenesis.

Riesner K, Shi Y, Jacobi A, Kräter M, Kalupa M, McGearey A, Mertlitz S, Cordes S, Schrezenmeier JF, Mengwasser J, Westphal S, Perez-Hernandez D, Schmitt C, Dittmar G, Guck J, Penack O.

Blood. 2017 Apr 6;129(14):2021-2032. doi: 10.1182/blood-2016-08-736314. Epub 2017 Jan 17.

27.

Bimodal antagonism of PKA signalling by ARHGAP36.

Eccles RL, Czajkowski MT, Barth C, Müller PM, McShane E, Grunwald S, Beaudette P, Mecklenburg N, Volkmer R, Zühlke K, Dittmar G, Selbach M, Hammes A, Daumke O, Klussmann E, Urbé S, Rocks O.

Nat Commun. 2016 Oct 7;7:12963. doi: 10.1038/ncomms12963.

28.

RNF4-Dependent Oncogene Activation by Protein Stabilization.

Thomas JJ, Abed M, Heuberger J, Novak R, Zohar Y, Beltran Lopez AP, Trausch-Azar JS, Ilagan MXG, Benhamou D, Dittmar G, Kopan R, Birchmeier W, Schwartz AL, Orian A.

Cell Rep. 2016 Sep 20;16(12):3388-3400. doi: 10.1016/j.celrep.2016.08.024.

29.

Sequential Poly-ubiquitylation by Specialized Conjugating Enzymes Expands the Versatility of a Quality Control Ubiquitin Ligase.

Weber A, Cohen I, Popp O, Dittmar G, Reiss Y, Sommer T, Ravid T, Jarosch E.

Mol Cell. 2016 Sep 1;63(5):827-39. doi: 10.1016/j.molcel.2016.07.020. Epub 2016 Aug 25.

30.

Resolving Lipid Mediators Maresin 1 and Resolvin D2 Prevent Atheroprogression in Mice.

Viola JR, Lemnitzer P, Jansen Y, Csaba G, Winter C, Neideck C, Silvestre-Roig C, Dittmar G, Döring Y, Drechsler M, Weber C, Zimmer R, Cenac N, Soehnlein O.

Circ Res. 2016 Oct 14;119(9):1030-1038. Epub 2016 Aug 16.

PMID:
27531933
31.

Muscle RING-finger 2 and 3 maintain striated-muscle structure and function.

Lodka D, Pahuja A, Geers-Knörr C, Scheibe RJ, Nowak M, Hamati J, Köhncke C, Purfürst B, Kanashova T, Schmidt S, Glass DJ, Morano I, Heuser A, Kraft T, Bassel-Duby R, Olson EN, Dittmar G, Sommer T, Fielitz J.

J Cachexia Sarcopenia Muscle. 2016 May;7(2):165-80. doi: 10.1002/jcsm.12057. Epub 2015 Sep 7.

32.

Metabolic Profiling as Well as Stable Isotope Assisted Metabolic and Proteomic Analysis of RAW 264.7 Macrophages Exposed to Ship Engine Aerosol Emissions: Different Effects of Heavy Fuel Oil and Refined Diesel Fuel.

Sapcariu SC, Kanashova T, Dilger M, Diabaté S, Oeder S, Passig J, Radischat C, Buters J, Sippula O, Streibel T, Paur HR, Schlager C, Mülhopt S, Stengel B, Rabe R, Harndorf H, Krebs T, Karg E, Gröger T, Weiss C, Dittmar G, Hiller K, Zimmermann R.

PLoS One. 2016 Jun 27;11(6):e0157964. doi: 10.1371/journal.pone.0157964. eCollection 2016.

33.

Organ siderosis and hemophagocytosis during acute graft-versus-host disease.

Nogai A, Shi Y, Pérez-Hernandez D, Cordes S, Mengwasser J, Mertlitz S, Riesner K, Kalupa M, Erdmann JH, Ziebig R, Dittmar G, Penack O.

Haematologica. 2016 Aug;101(8):e344-6. doi: 10.3324/haematol.2016.144519. Epub 2016 May 19. No abstract available.

34.

MicroRNA-34a promotes genomic instability by a broad suppression of genome maintenance mechanisms downstream of the oncogene KSHV-vGPCR.

Krause CJ, Popp O, Thirunarayanan N, Dittmar G, Lipp M, Müller G.

Oncotarget. 2016 Mar 1;7(9):10414-32. doi: 10.18632/oncotarget.7248.

35.

Proteomic Analysis of the Ubiquitin Landscape in the Drosophila Embryonic Nervous System and the Adult Photoreceptor Cells.

Ramirez J, Martinez A, Lectez B, Lee SY, Franco M, Barrio R, Dittmar G, Mayor U.

PLoS One. 2015 Oct 13;10(10):e0139083. doi: 10.1371/journal.pone.0139083. eCollection 2015.

36.

Proteomic techniques to probe the ubiquitin landscape.

Beaudette P, Popp O, Dittmar G.

Proteomics. 2016 Jan;16(2):273-87. doi: 10.1002/pmic.201500290. Epub 2015 Dec 15. Review.

PMID:
26460060
37.

The tRNA methyltransferase Dnmt2 is required for accurate polypeptide synthesis during haematopoiesis.

Tuorto F, Herbst F, Alerasool N, Bender S, Popp O, Federico G, Reitter S, Liebers R, Stoecklin G, Gröne HJ, Dittmar G, Glimm H, Lyko F.

EMBO J. 2015 Sep 14;34(18):2350-62. doi: 10.15252/embj.201591382. Epub 2015 Aug 13.

38.

Neutrophil serine proteases exert proteolytic activity on endothelial cells.

Jerke U, Hernandez DP, Beaudette P, Korkmaz B, Dittmar G, Kettritz R.

Kidney Int. 2015 Oct;88(4):764-75. doi: 10.1038/ki.2015.159. Epub 2015 Jun 10.

PMID:
26061547
39.

Particulate matter from both heavy fuel oil and diesel fuel shipping emissions show strong biological effects on human lung cells at realistic and comparable in vitro exposure conditions.

Oeder S, Kanashova T, Sippula O, Sapcariu SC, Streibel T, Arteaga-Salas JM, Passig J, Dilger M, Paur HR, Schlager C, Mülhopt S, Diabaté S, Weiss C, Stengel B, Rabe R, Harndorf H, Torvela T, Jokiniemi JK, Hirvonen MR, Schmidt-Weber C, Traidl-Hoffmann C, BéruBé KA, Wlodarczyk AJ, Prytherch Z, Michalke B, Krebs T, Prévôt AS, Kelbg M, Tiggesbäumker J, Karg E, Jakobi G, Scholtes S, Schnelle-Kreis J, Lintelmann J, Matuschek G, Sklorz M, Klingbeil S, Orasche J, Richthammer P, Müller L, Elsasser M, Reda A, Gröger T, Weggler B, Schwemer T, Czech H, Rüger CP, Abbaszade G, Radischat C, Hiller K, Buters JT, Dittmar G, Zimmermann R.

PLoS One. 2015 Jun 3;10(6):e0126536. doi: 10.1371/journal.pone.0126536. eCollection 2015.

40.

Differential proteomic analysis of mouse macrophages exposed to adsorbate-loaded heavy fuel oil derived combustion particles using an automated sample-preparation workflow.

Kanashova T, Popp O, Orasche J, Karg E, Harndorf H, Stengel B, Sklorz M, Streibel T, Zimmermann R, Dittmar G.

Anal Bioanal Chem. 2015 Aug;407(20):5965-76. doi: 10.1007/s00216-015-8595-4. Epub 2015 Mar 14.

PMID:
25772565
41.

Protein kinase Ymr291w/Tda1 is essential for glucose signaling in saccharomyces cerevisiae on the level of hexokinase isoenzyme ScHxk2 phosphorylation*.

Kaps S, Kettner K, Migotti R, Kanashova T, Krause U, Rödel G, Dittmar G, Kriegel TM.

J Biol Chem. 2015 Mar 6;290(10):6243-55. doi: 10.1074/jbc.M114.595074. Epub 2015 Jan 15.

42.

SILAC for biomarker discovery.

Dittmar G, Selbach M.

Proteomics Clin Appl. 2015 Apr;9(3-4):301-6. doi: 10.1002/prca.201400112. Epub 2015 Feb 10.

PMID:
25504673
43.

Quantitative dissection and modeling of the NF-κB p100-p105 module reveals interdependent precursor proteolysis.

Yılmaz ZB, Kofahl B, Beaudette P, Baum K, Ipenberg I, Weih F, Wolf J, Dittmar G, Scheidereit C.

Cell Rep. 2014 Dec 11;9(5):1756-1769. doi: 10.1016/j.celrep.2014.11.014. Epub 2014 Dec 4.

44.

Glioma-derived versican promotes tumor expansion via glioma-associated microglial/macrophages Toll-like receptor 2 signaling.

Hu F, Dzaye O, Hahn A, Yu Y, Scavetta RJ, Dittmar G, Kaczmarek AK, Dunning KR, Ricciardelli C, Rinnenthal JL, Heppner FL, Lehnardt S, Synowitz M, Wolf SA, Kettenmann H.

Neuro Oncol. 2015 Feb;17(2):200-10. doi: 10.1093/neuonc/nou324. Epub 2014 Dec 1.

45.

Using in vivo biotinylated ubiquitin to describe a mitotic exit ubiquitome from human cells.

Min M, Mayor U, Dittmar G, Lindon C.

Mol Cell Proteomics. 2014 Sep;13(9):2411-25. doi: 10.1074/mcp.M113.033498. Epub 2014 May 25.

46.

Ubiquitin profiling in liver using a transgenic mouse with biotinylated ubiquitin.

Lectez B, Migotti R, Lee SY, Ramirez J, Beraza N, Mansfield B, Sutherland JD, Martinez-Chantar ML, Dittmar G, Mayor U.

J Proteome Res. 2014 Jun 6;13(6):3016-26. doi: 10.1021/pr5001913. Epub 2014 Apr 30.

PMID:
24730562
47.

Inflammation-induced acute phase response in skeletal muscle and critical illness myopathy.

Langhans C, Weber-Carstens S, Schmidt F, Hamati J, Kny M, Zhu X, Wollersheim T, Koch S, Krebs M, Schulz H, Lodka D, Saar K, Labeit S, Spies C, Hubner N, Spranger J, Spuler S, Boschmann M, Dittmar G, Butler-Browne G, Mouly V, Fielitz J.

PLoS One. 2014 Mar 20;9(3):e92048. doi: 10.1371/journal.pone.0092048. eCollection 2014.

48.

PA28αβ reduces size and increases hydrophilicity of 20S immunoproteasome peptide products.

Raule M, Cerruti F, Benaroudj N, Migotti R, Kikuchi J, Bachi A, Navon A, Dittmar G, Cascio P.

Chem Biol. 2014 Apr 24;21(4):470-480. doi: 10.1016/j.chembiol.2014.02.006. Epub 2014 Mar 13.

49.

Identification of importin α 7 specific transport cargoes using a proteomic screening approach.

Hügel S, Depping R, Dittmar G, Rother F, Cabot R, Sury MD, Hartmann E, Bader M.

Mol Cell Proteomics. 2014 May;13(5):1286-98. doi: 10.1074/mcp.M112.026856. Epub 2014 Mar 12.

50.

Proteomic and functional consequences of hexokinase deficiency in glucose-repressible Kluyveromyces lactis.

Mates N, Kettner K, Heidenreich F, Pursche T, Migotti R, Kahlert G, Kuhlisch E, Breunig KD, Schellenberger W, Dittmar G, Hoflack B, Kriegel TM.

Mol Cell Proteomics. 2014 Mar;13(3):860-75. doi: 10.1074/mcp.M113.032714. Epub 2014 Jan 16.

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