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Items: 1 to 50 of 347

1.

Neurodevelopmental Outcomes in Neonates with Mild Hypoxic Ischemic Encephalopathy Treated with Therapeutic Hypothermia.

Rao R, Trivedi S, Distler A, Liao S, Vesoulis Z, Smyser C, Mathur AM.

Am J Perinatol. 2019 Nov;36(13):1337-1343. doi: 10.1055/s-0038-1676973. Epub 2019 Jan 4.

PMID:
30609430
2.

Activation of STAT3 integrates common profibrotic pathways to promote fibroblast activation and tissue fibrosis.

Chakraborty D, Šumová B, Mallano T, Chen CW, Distler A, Bergmann C, Ludolph I, Horch RE, Gelse K, Ramming A, Distler O, Schett G, Šenolt L, Distler JHW.

Nat Commun. 2017 Oct 24;8(1):1130. doi: 10.1038/s41467-017-01236-6.

3.

Essential role for histone deacetylase 11 (HDAC11) in neutrophil biology.

Sahakian E, Chen J, Powers JJ, Chen X, Maharaj K, Deng SL, Achille AN, Lienlaf M, Wang HW, Cheng F, Sodré AL, Distler A, Xing L, Perez-Villarroel P, Wei S, Villagra A, Seto E, Sotomayor EM, Horna P, Pinilla-Ibarz J.

J Leukoc Biol. 2017 Aug;102(2):475-486. doi: 10.1189/jlb.1A0415-176RRR. Epub 2017 May 26.

4.

JAK1-dependent transphosphorylation of JAK2 limits the antifibrotic effects of selective JAK2 inhibitors on long-term treatment.

Zhang Y, Liang R, Chen CW, Mallano T, Dees C, Distler A, Reich A, Bergmann C, Ramming A, Gelse K, Mielenz D, Distler O, Schett G, Distler JHW.

Ann Rheum Dis. 2017 Aug;76(8):1467-1475. doi: 10.1136/annrheumdis-2016-210911. Epub 2017 May 6.

PMID:
28478401
5.

Unification of de novo and acquired ibrutinib resistance in mantle cell lymphoma.

Zhao X, Lwin T, Silva A, Shah B, Tao J, Fang B, Zhang L, Fu K, Bi C, Li J, Jiang H, Meads MB, Jacobson T, Silva M, Distler A, Darville L, Zhang L, Han Y, Rebatchouk D, Di Liberto M, Moscinski LC, Koomen JM, Dalton WS, Shain KH, Wang M, Sotomayor E, Tao J.

Nat Commun. 2017 Apr 18;8:14920. doi: 10.1038/ncomms14920.

6.

An Ex Vivo Platform for the Prediction of Clinical Response in Multiple Myeloma.

Silva A, Silva MC, Sudalagunta P, Distler A, Jacobson T, Collins A, Nguyen T, Song J, Chen DT, Chen L, Cubitt C, Baz R, Perez L, Rebatchouk D, Dalton W, Greene J, Gatenby R, Gillies R, Sontag E, Meads MB, Shain KH.

Cancer Res. 2017 Jun 15;77(12):3336-3351. doi: 10.1158/0008-5472.CAN-17-0502. Epub 2017 Apr 11.

7.

A Dual Role of Upper Zone of Growth Plate and Cartilage Matrix-Associated Protein in Human and Mouse Osteoarthritic Cartilage: Inhibition of Aggrecanases and Promotion of Bone Turnover.

Stock M, Menges S, Eitzinger N, Geßlein M, Botschner R, Wormser L, Distler A, Schlötzer-Schrehardt U, Dietel K, Distler J, Beyer C, Gelse K, Engelke K, Koenders MI, van den Berg W, von der Mark K, Schett G.

Arthritis Rheumatol. 2017 Jun;69(6):1233-1245. doi: 10.1002/art.40042. Epub 2017 Apr 24.

8.

Corrigendum to "Fc-gamma receptors are not involved in cartilage damage during experimental osteoarthritis" [Osteoarthritis Cartilage 23 (2015) 1221-1225].

Stock M, Distler A, Distler J, Beyer C, Ruiz-Heiland G, Ipseiz N, Seeling M, Krönke G, Nimmerjahn F, Schett G.

Osteoarthritis Cartilage. 2017 Jun;25(6):995. doi: 10.1016/j.joca.2016.11.003. Epub 2016 Nov 17. No abstract available.

9.

Solar Trees: First Large-Scale Demonstration of Fully Solution Coated, Semitransparent, Flexible Organic Photovoltaic Modules.

Berny S, Blouin N, Distler A, Egelhaaf HJ, Krompiec M, Lohr A, Lozman OR, Morse GE, Nanson L, Pron A, Sauermann T, Seidler N, Tierney S, Tiwana P, Wagner M, Wilson H.

Adv Sci (Weinh). 2015 Dec 14;3(5):1500342. eCollection 2016 May.

10.

Composition of TWIST1 dimers regulates fibroblast activation and tissue fibrosis.

Palumbo-Zerr K, Soare A, Zerr P, Liebl A, Mancuso R, Tomcik M, Sumova B, Dees C, Chen CW, Wohlfahrt T, Mallano T, Distler A, Ramming A, Gelse K, Mihai C, Distler O, Schett G, Distler JH.

Ann Rheum Dis. 2017 Jan;76(1):244-251. doi: 10.1136/annrheumdis-2015-208470. Epub 2016 Apr 25.

PMID:
27113414
11.

Sterically controlled azomethine ylide cycloaddition polymerization of phenyl-C61-butyric acid methyl ester.

Stephen M, Ramanitra HH, Santos Silva H, Dowland S, Bégué D, Genevičius K, Arlauskas K, Juška G, Morse GE, Distler A, Hiorns RC.

Chem Commun (Camb). 2016 May 4;52(36):6107-10. doi: 10.1039/c6cc01380e. Epub 2016 Apr 12.

PMID:
27066898
12.

Inhibition of Notch1 promotes hedgehog signalling in a HES1-dependent manner in chondrocytes and exacerbates experimental osteoarthritis.

Lin NY, Distler A, Beyer C, Philipi-Schöbinger A, Breda S, Dees C, Stock M, Tomcik M, Niemeier A, Dell'Accio F, Gelse K, Mattson MP, Schett G, Distler JH.

Ann Rheum Dis. 2016 Nov;75(11):2037-2044. doi: 10.1136/annrheumdis-2015-208420. Epub 2016 Feb 5.

PMID:
26851274
13.

An Organotypic High Throughput System for Characterization of Drug Sensitivity of Primary Multiple Myeloma Cells.

Silva A, Jacobson T, Meads M, Distler A, Shain K.

J Vis Exp. 2015 Jul 15;(101):e53070. doi: 10.3791/53070.

14.

Inactivation of autophagy ameliorates glucocorticoid-induced and ovariectomy-induced bone loss.

Lin NY, Chen CW, Kagwiria R, Liang R, Beyer C, Distler A, Luther J, Engelke K, Schett G, Distler JH.

Ann Rheum Dis. 2016 Jun;75(6):1203-10. doi: 10.1136/annrheumdis-2015-207240. Epub 2015 Jun 25.

PMID:
26113650
15.

Nintedanib inhibits fibroblast activation and ameliorates fibrosis in preclinical models of systemic sclerosis.

Huang J, Beyer C, Palumbo-Zerr K, Zhang Y, Ramming A, Distler A, Gelse K, Distler O, Schett G, Wollin L, Distler JH.

Ann Rheum Dis. 2016 May;75(5):883-90. doi: 10.1136/annrheumdis-2014-207109. Epub 2015 Apr 9.

PMID:
25858641
16.

Stimulators of soluble guanylate cyclase (sGC) inhibit experimental skin fibrosis of different aetiologies.

Dees C, Beyer C, Distler A, Soare A, Zhang Y, Palumbo-Zerr K, Distler O, Schett G, Sandner P, Distler JH.

Ann Rheum Dis. 2015 Aug;74(8):1621-5. doi: 10.1136/annrheumdis-2014-206809. Epub 2015 Mar 27.

PMID:
25817717
17.

Fc-gamma receptors are not involved in cartilage damage during experimental osteoarthritis.

Stock M, Distler A, Distler J, Beyer C, Ruiz-Heiland G, Ipseiz N, Seeling M, Krönke G, Nimmerjahn F, Schett G.

Osteoarthritis Cartilage. 2015 Jul;23(7):1221-5. doi: 10.1016/j.joca.2015.02.019. Epub 2015 Mar 4. Erratum in: Osteoarthritis Cartilage. 2017 Jun;25(6):995.

18.

Tribbles homologue 3 stimulates canonical TGF-β signalling to regulate fibroblast activation and tissue fibrosis.

Tomcik M, Palumbo-Zerr K, Zerr P, Sumova B, Avouac J, Dees C, Distler A, Becvar R, Distler O, Schett G, Senolt L, Distler JH.

Ann Rheum Dis. 2016 Mar;75(3):609-16. doi: 10.1136/annrheumdis-2014-206234. Epub 2015 Jan 20.

PMID:
25603829
19.

Orphan nuclear receptor NR4A1 regulates transforming growth factor-β signaling and fibrosis.

Palumbo-Zerr K, Zerr P, Distler A, Fliehr J, Mancuso R, Huang J, Mielenz D, Tomcik M, Fürnrohr BG, Scholtysek C, Dees C, Beyer C, Krönke G, Metzger D, Distler O, Schett G, Distler JH.

Nat Med. 2015 Feb;21(2):150-8. doi: 10.1038/nm.3777. Epub 2015 Jan 12.

PMID:
25581517
21.

Cardiomyopathy in murine models of systemic sclerosis.

Venalis P, Kumánovics G, Schulze-Koops H, Distler A, Dees C, Zerr P, Palumbo-Zerr K, Czirják L, Mackevic Z, Lundberg IE, Distler O, Schett G, Distler JH.

Arthritis Rheumatol. 2015 Feb;67(2):508-16. doi: 10.1002/art.38942.

22.

N-acetyl-L-cysteine sensitizes pancreatic cancers to gemcitabine by targeting the NFκB pathway.

Qanungo S, Uys JD, Manevich Y, Distler AM, Shaner B, Hill EG, Mieyal JJ, Lemasters JJ, Townsend DM, Nieminen AL.

Biomed Pharmacother. 2014 Sep;68(7):855-64. doi: 10.1016/j.biopha.2014.08.007. Epub 2014 Aug 28.

23.

Histone deacetylase 11: A novel epigenetic regulator of myeloid derived suppressor cell expansion and function.

Sahakian E, Powers JJ, Chen J, Deng SL, Cheng F, Distler A, Woods DM, Rock-Klotz J, Sodre AL, Youn JI, Woan KV, Villagra A, Gabrilovich D, Sotomayor EM, Pinilla-Ibarz J.

Mol Immunol. 2015 Feb;63(2):579-85. doi: 10.1016/j.molimm.2014.08.002. Epub 2014 Aug 23.

24.

The nuclear receptor constitutive androstane receptor/NR1I3 enhances the profibrotic effects of transforming growth factor β and contributes to the development of experimental dermal fibrosis.

Avouac J, Palumbo-Zerr K, Ruzehaji N, Tomcik M, Zerr P, Dees C, Distler A, Beyer C, Schneider H, Distler O, Schett G, Allanore Y, Distler JH.

Arthritis Rheumatol. 2014 Nov;66(11):3140-50. doi: 10.1002/art.38819.

25.

S100A4 amplifies TGF-β-induced fibroblast activation in systemic sclerosis.

Tomcik M, Palumbo-Zerr K, Zerr P, Avouac J, Dees C, Sumova B, Distler A, Beyer C, Cerezo LA, Becvar R, Distler O, Grigorian M, Schett G, Senolt L, Distler JH.

Ann Rheum Dis. 2015 Sep;74(9):1748-55. doi: 10.1136/annrheumdis-2013-204516. Epub 2014 Apr 7.

PMID:
24709861
26.

Activation of liver X receptors inhibits experimental fibrosis by interfering with interleukin-6 release from macrophages.

Beyer C, Huang J, Beer J, Zhang Y, Palumbo-Zerr K, Zerr P, Distler A, Dees C, Maier C, Munoz L, Krönke G, Uderhardt S, Distler O, Jones S, Rose-John S, Oravecz T, Schett G, Distler JH.

Ann Rheum Dis. 2015 Jun;74(6):1317-24. doi: 10.1136/annrheumdis-2013-204401. Epub 2014 Mar 11.

PMID:
24618263
27.

Stimulation of the soluble guanylate cyclase (sGC) inhibits fibrosis by blocking non-canonical TGFβ signalling.

Beyer C, Zenzmaier C, Palumbo-Zerr K, Mancuso R, Distler A, Dees C, Zerr P, Huang J, Maier C, Pachowsky ML, Friebe A, Sandner P, Distler O, Schett G, Berger P, Distler JH.

Ann Rheum Dis. 2015 Jul;74(7):1408-16. doi: 10.1136/annrheumdis-2013-204508. Epub 2014 Feb 23.

PMID:
24567525
28.

Signature of circulating microRNAs in osteoarthritis.

Beyer C, Zampetaki A, Lin NY, Kleyer A, Perricone C, Iagnocco A, Distler A, Langley SR, Gelse K, Sesselmann S, Lorenzini R, Niemeier A, Swoboda B, Distler JH, Santer P, Egger G, Willeit J, Mayr M, Schett G, Kiechl S.

Ann Rheum Dis. 2015 Mar;74(3):e18. doi: 10.1136/annrheumdis-2013-204698. Epub 2014 Feb 10.

29.

Vitamin D receptor regulates TGF-β signalling in systemic sclerosis.

Zerr P, Vollath S, Palumbo-Zerr K, Tomcik M, Huang J, Distler A, Beyer C, Dees C, Gela K, Distler O, Schett G, Distler JH.

Ann Rheum Dis. 2015 Mar;74(3):e20. doi: 10.1136/annrheumdis-2013-204378. Epub 2014 Jan 21.

PMID:
24448349
30.

Combined inhibition of morphogen pathways demonstrates additive antifibrotic effects and improved tolerability.

Distler A, Lang V, Del Vecchio T, Huang J, Zhang Y, Beyer C, Lin NY, Palumbo-Zerr K, Distler O, Schett G, Distler JH.

Ann Rheum Dis. 2014 Jun;73(6):1264-8. doi: 10.1136/annrheumdis-2013-204221. Epub 2014 Jan 20.

PMID:
24445254
31.

Inhibition of casein kinase II reduces TGFβ induced fibroblast activation and ameliorates experimental fibrosis.

Zhang Y, Dees C, Beyer C, Lin NY, Distler A, Zerr P, Palumbo K, Susok L, Kreuter A, Distler O, Schett G, Distler JH.

Ann Rheum Dis. 2015 May;74(5):936-43. doi: 10.1136/annrheumdis-2013-204256. Epub 2014 Jan 15.

PMID:
24431397
32.

Inactivation of evenness interrupted (EVI) reduces experimental fibrosis by combined inhibition of canonical and non-canonical Wnt signalling.

Distler A, Ziemer C, Beyer C, Lin NY, Chen CW, Palumbo-Zerr K, Dees C, Weidemann A, Distler O, Schett G, Distler JH.

Ann Rheum Dis. 2014 Mar;73(3):624-7. doi: 10.1136/annrheumdis-2013-203995. Epub 2013 Nov 20.

PMID:
24257024
33.

Levels of target activation predict antifibrotic responses to tyrosine kinase inhibitors.

Maurer B, Distler A, Dees C, Khan K, Denton CP, Abraham D, Gay RE, Michel BA, Gay S, Hw Distler J, Distler O.

Ann Rheum Dis. 2013 Dec;72(12):2039-46. doi: 10.1136/annrheumdis-2013-203729. Epub 2013 Sep 7.

PMID:
24013728
34.

Vascular endothelial growth factor aggravates fibrosis and vasculopathy in experimental models of systemic sclerosis.

Maurer B, Distler A, Suliman YA, Gay RE, Michel BA, Gay S, Distler JH, Distler O.

Ann Rheum Dis. 2014 Oct;73(10):1880-7. doi: 10.1136/annrheumdis-2013-203535. Epub 2013 Aug 5.

PMID:
23918036
35.

The Wnt antagonists DKK1 and SFRP1 are downregulated by promoter hypermethylation in systemic sclerosis.

Dees C, Schlottmann I, Funke R, Distler A, Palumbo-Zerr K, Zerr P, Lin NY, Beyer C, Distler O, Schett G, Distler JH.

Ann Rheum Dis. 2014 Jun;73(6):1232-9. doi: 10.1136/annrheumdis-2012-203194. Epub 2013 May 22.

PMID:
23698475
36.

Open-label parallel dose tolerability study of three subcutaneous immunotherapy regimens in house dust mite allergic patients.

Rieker-Schwienbacher J, Nell MJ, Diamant Z, van Ree R, Distler A, Boot JD, Kleine-Tebbe J.

Clin Transl Allergy. 2013 May 8;3(1):16. doi: 10.1186/2045-7022-3-16.

37.

Vacuolar ATPase driven potassium transport in highly metastatic breast cancer cells.

Salyer SA, Olberding JR, Distler AA, Lederer ED, Clark BJ, Delamere NA, Khundmiri SJ.

Biochim Biophys Acta. 2013 Oct;1832(10):1734-43. doi: 10.1016/j.bbadis.2013.04.023. Epub 2013 Apr 29.

38.

Blockade of canonical Wnt signalling ameliorates experimental dermal fibrosis.

Beyer C, Reichert H, Akan H, Mallano T, Schramm A, Dees C, Palumbo-Zerr K, Lin NY, Distler A, Gelse K, Varga J, Distler O, Schett G, Distler JH.

Ann Rheum Dis. 2013 Jul;72(7):1255-8. doi: 10.1136/annrheumdis-2012-202544. Epub 2013 Apr 17.

PMID:
23595143
39.

Activation of pregnane X receptor inhibits experimental dermal fibrosis.

Beyer C, Skapenko A, Distler A, Dees C, Reichert H, Munoz L, Leipe J, Schulze-Koops H, Distler O, Schett G, Distler JH.

Ann Rheum Dis. 2013 Apr;72(4):621-5. doi: 10.1136/annrheumdis-2012-202476. Epub 2013 Jan 4.

PMID:
23291432
40.

Inactivation of tankyrases reduces experimental fibrosis by inhibiting canonical Wnt signalling.

Distler A, Deloch L, Huang J, Dees C, Lin NY, Palumbo-Zerr K, Beyer C, Weidemann A, Distler O, Schett G, Distler JH.

Ann Rheum Dis. 2013 Sep 1;72(9):1575-80. doi: 10.1136/annrheumdis-2012-202275. Epub 2012 Nov 12.

PMID:
23148305
41.

Autophagy regulates TNFα-mediated joint destruction in experimental arthritis.

Lin NY, Beyer C, Giessl A, Kireva T, Scholtysek C, Uderhardt S, Munoz LE, Dees C, Distler A, Wirtz S, Krönke G, Spencer B, Distler O, Schett G, Distler JH.

Ann Rheum Dis. 2013 May;72(5):761-8. doi: 10.1136/annrheumdis-2012-201671. Epub 2012 Sep 12.

PMID:
22975756
42.

Combined inhibition of c-Abl and PDGF receptors for prevention and treatment of murine sclerodermatous chronic graft-versus-host disease.

Zerr P, Distler A, Palumbo-Zerr K, Tomcik M, Vollath S, Dees C, Egberts F, Tinazzi I, Del Galdo F, Distler O, Schett G, Spriewald BM, Distler JH.

Am J Pathol. 2012 Nov;181(5):1672-80. doi: 10.1016/j.ajpath.2012.07.017. Epub 2012 Aug 31.

PMID:
22940072
43.

Inhibition of hedgehog signaling for the treatment of murine sclerodermatous chronic graft-versus-host disease.

Zerr P, Palumbo-Zerr K, Distler A, Tomcik M, Vollath S, Munoz LE, Beyer C, Dees C, Egberts F, Tinazzi I, Del Galdo F, Distler O, Schett G, Spriewald BM, Distler JH.

Blood. 2012 Oct 4;120(14):2909-17. doi: 10.1182/blood-2012-01-403428. Epub 2012 Aug 22.

44.

Inhibition of H3K27 histone trimethylation activates fibroblasts and induces fibrosis.

Krämer M, Dees C, Huang J, Schlottmann I, Palumbo-Zerr K, Zerr P, Gelse K, Beyer C, Distler A, Marquez VE, Distler O, Schett G, Distler JH.

Ann Rheum Dis. 2013 Apr;72(4):614-20. doi: 10.1136/annrheumdis-2012-201615. Epub 2012 Aug 21.

PMID:
22915621
45.

Inactivation of fatty acid amide hydrolase exacerbates experimental fibrosis by enhanced endocannabinoid-mediated activation of CB1.

Palumbo-Zerr K, Horn A, Distler A, Zerr P, Dees C, Beyer C, Selvi E, Cravatt BF, Distler O, Schett G, Distler JH.

Ann Rheum Dis. 2012 Dec;71(12):2051-4. doi: 10.1136/annrheumdis-2012-201823. Epub 2012 Aug 22.

PMID:
22915616
46.

Inhibition of sumoylation prevents experimental fibrosis.

Khodzhigorova A, Distler A, Lang V, Dees C, Schneider H, Beyer C, Gelse K, Distler O, Schett G, Distler JH.

Ann Rheum Dis. 2012 Nov;71(11):1904-8. doi: 10.1136/annrheumdis-2012-201746. Epub 2012 Aug 17. Erratum in: Ann Rheum Dis. 2013 Jun;72(6):1110.

PMID:
22904261
47.

Pomalidomide is effective for prevention and treatment of experimental skin fibrosis.

Weingärtner S, Zerr P, Tomcik M, Palumbo-Zerr K, Distler A, Dees C, Beyer C, Shankar SL, Cedzik D, Schafer PH, Distler O, Schett G, Distler JH.

Ann Rheum Dis. 2012 Nov;71(11):1895-9. doi: 10.1136/annrheumdis-2012-201784. Epub 2012 Aug 17.

PMID:
22904257
48.

JAK-2 as a novel mediator of the profibrotic effects of transforming growth factor β in systemic sclerosis.

Dees C, Tomcik M, Palumbo-Zerr K, Distler A, Beyer C, Lang V, Horn A, Zerr P, Zwerina J, Gelse K, Distler O, Schett G, Distler JH.

Arthritis Rheum. 2012 Sep;64(9):3006-15. doi: 10.1002/art.34500.

49.

Inactivation of a class A and a class C β-lactamase by 6β-(hydroxymethyl)penicillanic acid sulfone.

Papp-Wallace KM, Bethel CR, Gootz TD, Shang W, Stroh J, Lau W, McLeod D, Price L, Marfat A, Distler A, Drawz SM, Chen H, Harry E, Nottingham M, Carey PR, Buynak JD, Bonomo RA.

Biochem Pharmacol. 2012 Feb 15;83(4):462-71. doi: 10.1016/j.bcp.2011.11.015. Epub 2011 Dec 2.

50.

Do pharmacological and behavioral interventions differentially affect treatment outcome for children with social phobia?

Scharfstein LA, Beidel DC, Finnell LR, Distler A, Carter NT.

Behav Modif. 2011 Sep;35(5):451-67. doi: 10.1177/0145445511408590. Epub 2011 May 17.

PMID:
21586501

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