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Items: 1 to 50 of 52

1.

Targeting thapsigargin towards tumors.

Doan NT, Paulsen ES, Sehgal P, Møller JV, Nissen P, Denmeade SR, Isaacs JT, Dionne CA, Christensen SB.

Steroids. 2015 May;97:2-7. doi: 10.1016/j.steroids.2014.07.009. Epub 2014 Jul 24. Review.

2.

DNA base identification by electron microscopy.

Bell DC, Thomas WK, Murtagh KM, Dionne CA, Graham AC, Anderson JE, Glover WR.

Microsc Microanal. 2012 Oct;18(5):1049-53. doi: 10.1017/S1431927612012615. Epub 2012 Oct 9.

PMID:
23046798
3.

Engineering a prostate-specific membrane antigen-activated tumor endothelial cell prodrug for cancer therapy.

Denmeade SR, Mhaka AM, Rosen DM, Brennen WN, Dalrymple S, Dach I, Olesen C, Gurel B, Demarzo AM, Wilding G, Carducci MA, Dionne CA, Møller JV, Nissen P, Christensen SB, Isaacs JT.

Sci Transl Med. 2012 Jun 27;4(140):140ra86. doi: 10.1126/scitranslmed.3003886. Erratum in: Sci Transl Med. 2012 Jul 18;4(143):143er4.

4.

Detecting buried metallic weapons in a controlled setting using a conductivity meter.

Dionne CA, Schultz JJ, Murdock RA 2nd, Smith SA.

Forensic Sci Int. 2011 May 20;208(1-3):18-24. doi: 10.1016/j.forsciint.2010.10.019. Epub 2010 Nov 13.

PMID:
21075570
5.

Discrimination of falls and blows in blunt head trauma: systematic study of the hat brim line rule in relation to skull fractures.

Kremer C, Racette S, Dionne CA, Sauvageau A.

J Forensic Sci. 2008 May;53(3):716-9. doi: 10.1111/j.1556-4029.2008.00725.x.

PMID:
18471221
6.

Pharmacokinetics, biodistribution, and antitumor efficacy of a human glandular kallikrein 2 (hK2)-activated thapsigargin prodrug.

Janssen S, Rosen DM, Ricklis RM, Dionne CA, Lilja H, Christensen SB, Isaacs JT, Denmeade SR.

Prostate. 2006 Mar 1;66(4):358-68.

PMID:
16302271
7.
8.

The neurotrophin-trk receptor axes are critical for the growth and progression of human prostatic carcinoma and pancreatic ductal adenocarcinoma xenografts in nude mice.

Miknyoczki SJ, Wan W, Chang H, Dobrzanski P, Ruggeri BA, Dionne CA, Buchkovich K.

Clin Cancer Res. 2002 Jun;8(6):1924-31.

9.

Pan-trk inhibition decreases metastasis and enhances host survival in experimental models as a result of its selective induction of apoptosis of prostate cancer cells.

Weeraratna AT, Dalrymple SL, Lamb JC, Denmeade SR, Miknyoczki S, Dionne CA, Isaacs JT.

Clin Cancer Res. 2001 Aug;7(8):2237-45.

10.

Antitumor activity of CEP-751 (KT-6587) on human neuroblastoma and medulloblastoma xenografts.

Evans AE, Kisselbach KD, Yamashiro DJ, Ikegaki N, Camoratto AM, Dionne CA, Brodeur GM.

Clin Cancer Res. 1999 Nov;5(11):3594-602.

11.

A cytomegalovirus-encoded mitochondria-localized inhibitor of apoptosis structurally unrelated to Bcl-2.

Goldmacher VS, Bartle LM, Skaletskaya A, Dionne CA, Kedersha NL, Vater CA, Han JW, Lutz RJ, Watanabe S, Cahir McFarland ED, Kieff ED, Mocarski ES, Chittenden T.

Proc Natl Acad Sci U S A. 1999 Oct 26;96(22):12536-41.

12.
13.
14.
15.

Neurotrophins and Trk receptors in human pancreatic ductal adenocarcinoma: expression patterns and effects on in vitro invasive behavior.

Miknyoczki SJ, Lang D, Huang L, Klein-Szanto AJ, Dionne CA, Ruggeri BA.

Int J Cancer. 1999 May 5;81(3):417-27.

16.

BNIP3alpha: a human homolog of mitochondrial proapoptotic protein BNIP3.

Yasuda M, Han JW, Dionne CA, Boyd JM, Chinnadurai G.

Cancer Res. 1999 Feb 1;59(3):533-7.

17.

Immunolocalization of the mitogen-activated protein kinases p42MAPK and JNK1, and their regulatory kinases MEK1 and MEK4, in adult rat central nervous system.

Flood DG, Finn JP, Walton KM, Dionne CA, Contreras PC, Miller MS, Bhat RV.

J Comp Neurol. 1998 Aug 31;398(3):373-92.

PMID:
9714150
18.

Cell cycle-independent death of prostate adenocarcinoma is induced by the trk tyrosine kinase inhibitor CEP-751 (KT6587).

Dionne CA, Camoratto AM, Jani JP, Emerson E, Neff N, Vaught JL, Murakata C, Djakiew D, Lamb J, Bova S, George D, Isaacs JT.

Clin Cancer Res. 1998 Aug;4(8):1887-98.

19.

CEP-1347/KT7515 prevents motor neuronal programmed cell death and injury-induced dedifferentiation in vivo.

Glicksman MA, Chiu AY, Dionne CA, Harty M, Kaneko M, Murakata C, Oppenheim RW, Prevette D, Sengelaub DR, Vaught JL, Neff NT.

J Neurobiol. 1998 Jun 15;35(4):361-70.

PMID:
9624618
20.

Region-specific targets of p42/p44MAPK signaling in rat brain.

Bhat RV, Engber TM, Finn JP, Koury EJ, Contreras PC, Miller MS, Dionne CA, Walton KM.

J Neurochem. 1998 Feb;70(2):558-71.

21.

Kinetics of trkA tyrosine kinase activity and inhibition by K-252a.

Angeles TS, Yang SX, Steffler C, Dionne CA.

Arch Biochem Biophys. 1998 Jan 15;349(2):267-74.

PMID:
9448714
22.

Motoneuron apoptosis is blocked by CEP-1347 (KT 7515), a novel inhibitor of the JNK signaling pathway.

Maroney AC, Glicksman MA, Basma AN, Walton KM, Knight E Jr, Murphy CA, Bartlett BA, Finn JP, Angeles T, Matsuda Y, Neff NT, Dionne CA.

J Neurosci. 1998 Jan 1;18(1):104-11.

23.

CEP-751 inhibits TRK receptor tyrosine kinase activity in vitro exhibits anti-tumor activity.

Camoratto AM, Jani JP, Angeles TS, Maroney AC, Sanders CY, Murakata C, Neff NT, Vaught JL, Isaacs JT, Dionne CA.

Int J Cancer. 1997 Aug 7;72(4):673-9.

24.

Neurotrophic 3,9-bis[(alkylthio)methyl]-and-bis(alkoxymethyl)-K-252a derivatives.

Kaneko M, Saito Y, Saito H, Matsumoto T, Matsuda Y, Vaught JL, Dionne CA, Angeles TS, Glicksman MA, Neff NT, Rotella DP, Kauer JC, Mallamo JP, Hudkins RL, Murakata C.

J Med Chem. 1997 Jun 6;40(12):1863-9.

PMID:
9191963
25.

A radioactive binding assay for inhibitors of trkA kinase.

Knight E Jr, Connors TJ, Maroney AC, Angeles TS, Hudkins RL, Dionne CA.

Anal Biochem. 1997 May 1;247(2):376-81.

PMID:
9177701
27.

K-252b potentiation of neurotrophin-3 is trkA specific in cells lacking p75NTR.

Maroney AC, Sanders C, Neff NT, Dionne CA.

J Neurochem. 1997 Jan;68(1):88-94.

28.
29.

Enzyme-linked immunosorbent assay for trkA tyrosine kinase activity.

Angeles TS, Steffler C, Bartlett BA, Hudkins RL, Stephens RM, Kaplan DR, Dionne CA.

Anal Biochem. 1996 Apr 5;236(1):49-55.

PMID:
8619495
30.

K-252a induces tyrosine phosphorylation of the focal adhesion kinase and neurite outgrowth in human neuroblastoma SH-SY5Y cells.

Maroney AC, Lipfert L, Forbes ME, Glicksman MA, Neff NT, Siman R, Dionne CA.

J Neurochem. 1995 Feb;64(2):540-9.

PMID:
7830046
31.

Activation of fibroblast growth factor (FGF) receptors by recombinant human FGF-5.

Clements DA, Wang JK, Dionne CA, Goldfarb M.

Oncogene. 1993 May;8(5):1311-6.

PMID:
8386828
32.

The use of polymerase chain reaction for chromosome assignment.

Jaye M, Dionne CA.

Methods Mol Biol. 1993;15:89-94. doi: 10.1385/0-89603-244-2:89.

PMID:
21400267
33.

Chromosome assignment by polymerase chain reaction techniques.

Dionne CA, Jaye M.

Methods Enzymol. 1993;218:402-13. No abstract available.

PMID:
8510542
34.
36.

Point mutation in FGF receptor eliminates phosphatidylinositol hydrolysis without affecting mitogenesis.

Mohammadi M, Dionne CA, Li W, Li N, Spivak T, Honegger AM, Jaye M, Schlessinger J.

Nature. 1992 Aug 20;358(6388):681-4.

PMID:
1379698
37.

Fibroblast growth factor receptor tyrosine kinases: molecular analysis and signal transduction.

Jaye M, Schlessinger J, Dionne CA.

Biochim Biophys Acta. 1992 Jun 10;1135(2):185-99. Review. No abstract available.

PMID:
1319744
38.

BEK, a receptor for multiple members of the fibroblast growth factor (FGF) family, maps to human chromosome 10q25.3----q26.

Dionne CA, Modi WS, Crumley G, O'Brien SJ, Schlessinger J, Jaye M.

Cytogenet Cell Genet. 1992;60(1):34-6.

PMID:
1582255
39.

Acidic fibroblast growth factor accelerates the healing of acetic-acid-induced gastric ulcers in rats.

Fitzpatrick LR, Jakubowska A, Martin GE, Davis M, Jaye MC, Dionne CA.

Digestion. 1992;53(1-2):17-27.

PMID:
1283855
40.

High-affinity binding and activation of a truncated FGF receptor by both aFGF and bFGF.

Crumley G, Bellot F, Kaplow JM, Schlessinger J, Jaye M, Dionne CA.

Oncogene. 1991 Dec;6(12):2255-62.

PMID:
1722570
41.

A tyrosine-phosphorylated carboxy-terminal peptide of the fibroblast growth factor receptor (Flg) is a binding site for the SH2 domain of phospholipase C-gamma 1.

Mohammadi M, Honegger AM, Rotin D, Fischer R, Bellot F, Li W, Dionne CA, Jaye M, Rubinstein M, Schlessinger J.

Mol Cell Biol. 1991 Oct;11(10):5068-78.

42.

Ligand-induced transphosphorylation between different FGF receptors.

Bellot F, Crumley G, Kaplow JM, Schlessinger J, Jaye M, Dionne CA.

EMBO J. 1991 Oct;10(10):2849-54.

43.

Temporal, differential and regional expression of mRNA for basic fibroblast growth factor in the developing and adult rat brain.

Powell PP, Finklestein SP, Dionne CA, Jaye M, Klagsbrun M.

Brain Res Mol Brain Res. 1991 Aug;11(1):71-7.

PMID:
1662747
44.

BEK and FLG, two receptors to members of the FGF family, are amplified in subsets of human breast cancers.

Adnane J, Gaudray P, Dionne CA, Crumley G, Jaye M, Schlessinger J, Jeanteur P, Birnbaum D, Theillet C.

Oncogene. 1991 Apr;6(4):659-63.

PMID:
1851551
45.

Acidic fibroblast growth factor, heart development, and capillary angiogenesis.

Engelmann GL, Dionne CA, Jaye MC.

Ann N Y Acad Sci. 1991;638:463-6. No abstract available.

PMID:
1723861
46.

Structural diversity and binding of FGF receptors.

Dionne CA, Jaye M, Schlessinger J.

Ann N Y Acad Sci. 1991;638:161-6. Review. No abstract available.

PMID:
1664682
47.

Effect of heparin on the binding affinity of acidic FGF for the cloned human FGF receptors, flg and bek.

Kaplow JM, Bellot F, Crumley G, Dionne CA, Jaye M.

Biochem Biophys Res Commun. 1990 Oct 15;172(1):107-12.

PMID:
1699533
48.

Characterization and cDNA cloning of phospholipase C-gamma, a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase.

Burgess WH, Dionne CA, Kaplow J, Mudd R, Friesel R, Zilberstein A, Schlessinger J, Jaye M.

Mol Cell Biol. 1990 Sep;10(9):4770-7.

49.

Cloning and expression of two distinct high-affinity receptors cross-reacting with acidic and basic fibroblast growth factors.

Dionne CA, Crumley G, Bellot F, Kaplow JM, Searfoss G, Ruta M, Burgess WH, Jaye M, Schlessinger J.

EMBO J. 1990 Sep;9(9):2685-92.

50.

The gene for human acidic fibroblast growth factor encodes two upstream exons alternatively spliced to the first coding exon.

Crumley G, Dionne CA, Jaye M.

Biochem Biophys Res Commun. 1990 Aug 31;171(1):7-13.

PMID:
2393407

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