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Items: 32


Antibiotic Resistance Gene Diversity and Virulence Gene Diversity Are Correlated in Human Gut and Environmental Microbiomes.

Escudeiro P, Pothier J, Dionisio F, Nogueira T.

mSphere. 2019 May 1;4(3). pii: e00135-19. doi: 10.1128/mSphere.00135-19.


Lentiviral haemopoietic stem/progenitor cell gene therapy for treatment of Wiskott-Aldrich syndrome: interim results of a non-randomised, open-label, phase 1/2 clinical study.

Ferrua F, Cicalese MP, Galimberti S, Giannelli S, Dionisio F, Barzaghi F, Migliavacca M, Bernardo ME, Calbi V, Assanelli AA, Facchini M, Fossati C, Albertazzi E, Scaramuzza S, Brigida I, Scala S, Basso-Ricci L, Pajno R, Casiraghi M, Canarutto D, Salerio FA, Albert MH, Bartoli A, Wolf HM, Fiori R, Silvani P, Gattillo S, Villa A, Biasco L, Dott C, Culme-Seymour EJ, van Rossem K, Atkinson G, Valsecchi MG, Roncarolo MG, Ciceri F, Naldini L, Aiuti A.

Lancet Haematol. 2019 May;6(5):e239-e253. doi: 10.1016/S2352-3026(19)30021-3. Epub 2019 Apr 10.


Interactions between plasmids and other mobile genetic elements affect their transmission and persistence.

Dionisio F, Zilhão R, Gama JA.

Plasmid. 2019 Mar;102:29-36. doi: 10.1016/j.plasmid.2019.01.003. Epub 2019 Feb 14. Review.


Dynamics of genetically engineered hematopoietic stem and progenitor cells after autologous transplantation in humans.

Scala S, Basso-Ricci L, Dionisio F, Pellin D, Giannelli S, Salerio FA, Leonardelli L, Cicalese MP, Ferrua F, Aiuti A, Biasco L.

Nat Med. 2018 Nov;24(11):1683-1690. doi: 10.1038/s41591-018-0195-3. Epub 2018 Oct 1.


T-cell defects in patients with ARPC1B germline mutations account for combined immunodeficiency.

Brigida I, Zoccolillo M, Cicalese MP, Pfajfer L, Barzaghi F, Scala S, Oleaga-Quintas C, Álvarez-Álvarez JA, Sereni L, Giannelli S, Sartirana C, Dionisio F, Pavesi L, Benavides-Nieto M, Basso-Ricci L, Capasso P, Mazzi B, Rosain J, Marcus N, Lee YN, Somech R, Degano M, Raiola G, Caorsi R, Picco P, Moncada Velez M, Khourieh J, Arias AA, Bousfiha A, Issekutz T, Issekutz A, Boisson B, Dobbs K, Villa A, Lombardo A, Neven B, Moshous D, Casanova JL, Franco JL, Notarangelo LD, Scielzo C, Volpi S, Dupré L, Bustamante J, Gattorno M, Aiuti A.

Blood. 2018 Nov 29;132(22):2362-2374. doi: 10.1182/blood-2018-07-863431. Epub 2018 Sep 25.


Impact of plasmid interactions with the chromosome and other plasmids on the spread of antibiotic resistance.

Gama JA, Zilhão R, Dionisio F.

Plasmid. 2018 Sep;99:82-88. doi: 10.1016/j.plasmid.2018.09.009. Epub 2018 Sep 19. Review.


Successful Treatment With Ledipasvir/Sofosbuvir in an Infant With Severe Combined Immunodeficiency Caused by Adenosine Deaminase Deficiency With HCV Allowed Gene Therapy with Strimvelis.

Tucci F, Calbi V, Barzaghi F, Migliavacca M, Ferrua F, Bernardo ME, Canarutto D, Consiglieri G, Recupero S, Calzatini F, Gabaldo M, Lucano C, Casiraghi M, Darin S, Dionisio F, Marktel S, Cestone E, Finazzi R, Mieli-Vergani G, Boeri E, Appleby J, Abd Elaziz D, Ciceri F, Aiuti A, Cicalese MP.

Hepatology. 2018 Dec;68(6):2434-2437. doi: 10.1002/hep.30160. Epub 2018 Nov 13. No abstract available.


First Occurrence of Plasmablastic Lymphoma in Adenosine Deaminase-Deficient Severe Combined Immunodeficiency Disease Patient and Review of the Literature.

Migliavacca M, Assanelli A, Ponzoni M, Pajno R, Barzaghi F, Giglio F, Ferrua F, Frittoli M, Brigida I, Dionisio F, Nicoletti R, Casiraghi M, Roncarolo MG, Doglioni C, Peccatori J, Ciceri F, Cicalese MP, Aiuti A.

Front Immunol. 2018 Feb 2;9:113. doi: 10.3389/fimmu.2018.00113. eCollection 2018. Review.


Maintenance of Microbial Cooperation Mediated by Public Goods in Single- and Multiple-Trait Scenarios

Özkaya Ö, Xavier KB, Dionisio F, Balbontín R.

J Bacteriol. 2017 Nov 15;199(22). pii: JB.00297-17. doi: 10.1128/JB.00297-17. Epub 2017 Aug 28.


Multiple plasmid interference - Pledging allegiance to my enemy's enemy.

Gama JA, Zilhão R, Dionisio F.

Plasmid. 2017 Sep;93:17-23. doi: 10.1016/j.plasmid.2017.08.002. Epub 2017 Aug 24.


Co-resident plasmids travel together.

Gama JA, Zilhão R, Dionisio F.

Plasmid. 2017 Sep;93:24-29. doi: 10.1016/j.plasmid.2017.08.004. Epub 2017 Aug 24.


Transmission Fitness in Co-colonization and the Persistence of Bacterial Pathogens.

Gaivão M, Dionisio F, Gjini E.

Bull Math Biol. 2017 Sep;79(9):2068-2087. doi: 10.1007/s11538-017-0320-3. Epub 2017 Jul 24.


Social behaviour involving drug resistance: the role of initial density, initial frequency and population structure in shaping the effect of antibiotic resistance as a public good.

Domingues IL, Gama JA, Carvalho LM, Dionisio F.

Heredity (Edinb). 2017 Nov;119(5):295-301. doi: 10.1038/hdy.2017.33. Epub 2017 Jun 21.


In Vivo Tracking of Human Hematopoiesis Reveals Patterns of Clonal Dynamics during Early and Steady-State Reconstitution Phases.

Biasco L, Pellin D, Scala S, Dionisio F, Basso-Ricci L, Leonardelli L, Scaramuzza S, Baricordi C, Ferrua F, Cicalese MP, Giannelli S, Neduva V, Dow DJ, Schmidt M, Von Kalle C, Roncarolo MG, Ciceri F, Vicard P, Wit E, Di Serio C, Naldini L, Aiuti A.

Cell Stem Cell. 2016 Jul 7;19(1):107-19. doi: 10.1016/j.stem.2016.04.016. Epub 2016 May 26.


Update on the safety and efficacy of retroviral gene therapy for immunodeficiency due to adenosine deaminase deficiency.

Cicalese MP, Ferrua F, Castagnaro L, Pajno R, Barzaghi F, Giannelli S, Dionisio F, Brigida I, Bonopane M, Casiraghi M, Tabucchi A, Carlucci F, Grunebaum E, Adeli M, Bredius RG, Puck JM, Stepensky P, Tezcan I, Rolfe K, De Boever E, Reinhardt RR, Appleby J, Ciceri F, Roncarolo MG, Aiuti A.

Blood. 2016 Jul 7;128(1):45-54. doi: 10.1182/blood-2016-01-688226. Epub 2016 Apr 29. Erratum in: Blood. 2017 Jun 15;129(24):3271.


Tracking genetically engineered lymphocytes long-term reveals the dynamics of T cell immunological memory.

Oliveira G, Ruggiero E, Stanghellini MT, Cieri N, D'Agostino M, Fronza R, Lulay C, Dionisio F, Mastaglio S, Greco R, Peccatori J, Aiuti A, Ambrosi A, Biasco L, Bondanza A, Lambiase A, Traversari C, Vago L, von Kalle C, Schmidt M, Bordignon C, Ciceri F, Bonini C.

Sci Transl Med. 2015 Dec 9;7(317):317ra198. doi: 10.1126/scitranslmed.aac8265. Erratum in: Sci Transl Med. 2015 Dec 23;7(319):319er9. D'Agostino, Mattio [corrected to D'Agostino, Mattia].


Lower within-community variance of negative density dependence increases forest diversity.

Miranda A, Carvalho LM, Dionisio F.

PLoS One. 2015 May 20;10(5):e0127260. doi: 10.1371/journal.pone.0127260. eCollection 2015.


Shedding of clinical-grade lentiviral vectors is not detected in a gene therapy setting.

Cesani M, Plati T, Lorioli L, Benedicenti F, Redaelli D, Dionisio F, Biasco L, Montini E, Naldini L, Biffi A.

Gene Ther. 2015 Jun;22(6):496-502. doi: 10.1038/gt.2015.10. Epub 2015 Mar 12.


In vivo tracking of T cells in humans unveils decade-long survival and activity of genetically modified T memory stem cells.

Biasco L, Scala S, Basso Ricci L, Dionisio F, Baricordi C, Calabria A, Giannelli S, Cieri N, Barzaghi F, Pajno R, Al-Mousa H, Scarselli A, Cancrini C, Bordignon C, Roncarolo MG, Montini E, Bonini C, Aiuti A.

Sci Transl Med. 2015 Feb 4;7(273):273ra13. doi: 10.1126/scitranslmed.3010314.


Lentiviral hematopoietic stem cell gene therapy in patients with Wiskott-Aldrich syndrome.

Aiuti A, Biasco L, Scaramuzza S, Ferrua F, Cicalese MP, Baricordi C, Dionisio F, Calabria A, Giannelli S, Castiello MC, Bosticardo M, Evangelio C, Assanelli A, Casiraghi M, Di Nunzio S, Callegaro L, Benati C, Rizzardi P, Pellin D, Di Serio C, Schmidt M, Von Kalle C, Gardner J, Mehta N, Neduva V, Dow DJ, Galy A, Miniero R, Finocchi A, Metin A, Banerjee PP, Orange JS, Galimberti S, Valsecchi MG, Biffi A, Montini E, Villa A, Ciceri F, Roncarolo MG, Naldini L.

Science. 2013 Aug 23;341(6148):1233151. doi: 10.1126/science.1233151. Epub 2013 Jul 11.


Temperate bacterial viruses as double-edged swords in bacterial warfare.

Gama JA, Reis AM, Domingues I, Mendes-Soares H, Matos AM, Dionisio F.

PLoS One. 2013;8(3):e59043. doi: 10.1371/journal.pone.0059043. Epub 2013 Mar 11.


Immune subversion and quorum-sensing shape the variation in infectious dose among bacterial pathogens.

Gama JA, Abby SS, Vieira-Silva S, Dionisio F, Rocha EP.

PLoS Pathog. 2012 Feb;8(2):e1002503. doi: 10.1371/journal.ppat.1002503. Epub 2012 Feb 2.


Pervasive sign epistasis between conjugative plasmids and drug-resistance chromosomal mutations.

Silva RF, Mendonça SC, Carvalho LM, Reis AM, Gordo I, Trindade S, Dionisio F.

PLoS Genet. 2011 Jul;7(7):e1002181. doi: 10.1371/journal.pgen.1002181. Epub 2011 Jul 28.


Positive epistasis drives the acquisition of multidrug resistance.

Trindade S, Sousa A, Xavier KB, Dionisio F, Ferreira MG, Gordo I.

PLoS Genet. 2009 Jul;5(7):e1000578. doi: 10.1371/journal.pgen.1000578. Epub 2009 Jul 24.


Paternity analysis in Excel.

Rocheta M, Dionísio FM, Fonseca L, Pires AM.

Comput Methods Programs Biomed. 2007 Dec;88(3):234-8. Epub 2007 Oct 24.


Small-world networks decrease the speed of Muller's ratchet.

Combadão J, Campos PR, Dionisio F, Gordo I.

Genet Res. 2007 Feb;89(1):7-18.


Muller's ratchet in random graphs and scale-free networks.

Campos PR, Combadão J, Dionisio F, Gordo I.

Phys Rev E Stat Nonlin Soft Matter Phys. 2006 Oct;74(4 Pt 1):042901. Epub 2006 Oct 4.


The evolution of a conjugative plasmid and its ability to increase bacterial fitness.

Dionisio F, Conceição IC, Marques AC, Fernandes L, Gordo I.

Biol Lett. 2005 Jun 22;1(2):250-2.


Nonequilibrium model for estimating parameters of deleterious mutations.

Gordo I, Dionisio F.

Phys Rev E Stat Nonlin Soft Matter Phys. 2005 Mar;71(3 Pt 1):031907. Epub 2005 Mar 18.


Plasmids spread very fast in heterogeneous bacterial communities.

Dionisio F, Matic I, Radman M, Rodrigues OR, Taddei F.

Genetics. 2002 Dec;162(4):1525-32.


Molecular keys to speciation: DNA polymorphism and the control of genetic exchange in enterobacteria.

Vulić M, Dionisio F, Taddei F, Radman M.

Proc Natl Acad Sci U S A. 1997 Sep 2;94(18):9763-7.

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