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Items: 17


Expression of a soluble IL-10 receptor enhances the therapeutic effects of a papillomavirus-associated antitumor vaccine in a murine model.

Silva JR, Sales NS, Silva MO, Aps LRMM, Moreno ACR, Rodrigues EG, Ferreira LCS, Diniz MO.

Cancer Immunol Immunother. 2019 May;68(5):753-763. doi: 10.1007/s00262-018-02297-2. Epub 2019 Feb 26.


In vivo electroporation enhances vaccine-mediated therapeutic control of human papilloma virus-associated tumors by the activation of multifunctional and effector memory CD8+ T cells.

Sales NS, Silva JR, Aps LRMM, Silva MO, Porchia BFMM, Ferreira LCS, Diniz MO.

Vaccine. 2017 Dec 19;35(52):7240-7249. doi: 10.1016/j.vaccine.2017.11.011. Epub 2017 Nov 22.


Induction of resident memory T cells enhances the efficacy of cancer vaccine.

Nizard M, Roussel H, Diniz MO, Karaki S, Tran T, Voron T, Dransart E, Sandoval F, Riquet M, Rance B, Marcheteau E, Fabre E, Mandavit M, Terme M, Blanc C, Escudie JB, Gibault L, Barthes FLP, Granier C, Ferreira LCS, Badoual C, Johannes L, Tartour E.

Nat Commun. 2017 May 24;8:15221. doi: 10.1038/ncomms15221.


Herpes Simplex Virus Glycoprotein D Targets a Specific Dendritic Cell Subset and Improves the Performance of Vaccines to Human Papillomavirus-Associated Tumors.

Porchia BFMM, Moreno ACR, Ramos RN, Diniz MO, de Andrade LHTM, Rosa DS, Barbuto JAM, Boscardin SB, Ferreira LCS.

Mol Cancer Ther. 2017 Sep;16(9):1922-1933. doi: 10.1158/1535-7163.MCT-17-0071. Epub 2017 May 18.


Gene delivery and immunomodulatory effects of plasmid DNA associated with Branched Amphiphilic Peptide Capsules.

Avila LA, Aps LRMM, Ploscariu N, Sukthankar P, Guo R, Wilkinson KE, Games P, Szoszkiewicz R, Alves RPS, Diniz MO, Fang Y, Ferreira LCS, Tomich JM.

J Control Release. 2016 Nov 10;241:15-24. doi: 10.1016/j.jconrel.2016.08.042. Epub 2016 Sep 1.


Protection against HPV-16-Associated Tumors Requires the Activation of CD8+ Effector Memory T Cells and the Control of Myeloid-Derived Suppressor Cells.

Diniz MO, Sales NS, Silva JR, Ferreira LC.

Mol Cancer Ther. 2016 Aug;15(8):1920-30. doi: 10.1158/1535-7163.MCT-15-0742. Epub 2016 May 24.


Bacterial spores as particulate carriers for gene gun delivery of plasmid DNA.

Aps LRMM, Tavares MB, Rozenfeld JHK, Lamy MT, Ferreira LCS, Diniz MO.

J Biotechnol. 2016 Jun 20;228:58-66. doi: 10.1016/j.jbiotec.2016.04.027. Epub 2016 Apr 27.


A Therapeutic Her2/neu Vaccine Targeting Dendritic Cells Preferentially Inhibits the Growth of Low Her2/neu-Expressing Tumor in HLA-A2 Transgenic Mice.

Tran T, Diniz MO, Dransart E, Gey A, Merillon N, Lone YC, Godefroy S, Sibley C, Ferreira LC, Medioni J, Oudard S, Johannes L, Tartour E.

Clin Cancer Res. 2016 Aug 15;22(16):4133-44. doi: 10.1158/1078-0432.CCR-16-0044. Epub 2016 Mar 22.


Bacillus subtilis spores as adjuvants for DNA vaccines.

Aps LR, Diniz MO, Porchia BF, Sales NS, Moreno AC, Ferreira LC.

Vaccine. 2015 May 11;33(20):2328-34. doi: 10.1016/j.vaccine.2015.03.043. Epub 2015 Mar 27.


Mucosal vaccines: novel strategies and applications for the control of pathogens and tumors at mucosal sites.

Nizard M, Diniz MO, Roussel H, Tran T, Ferreira LC, Badoual C, Tartour E.

Hum Vaccin Immunother. 2014;10(8):2175-87. doi: 10.4161/hv.29269. Review.


Enhanced therapeutic effects conferred by an experimental DNA vaccine targeting human papillomavirus-induced tumors.

Diniz MO, Cariri FA, Aps LR, Ferreira LC.

Hum Gene Ther. 2013 Oct;24(10):861-70. doi: 10.1089/hum.2013.102.


Bicistronic DNA vaccines simultaneously encoding HIV, HSV and HPV antigens promote CD8⁺ T cell responses and protective immunity.

Santana VC, Diniz MO, Cariri FA, Ventura AM, Cunha-Neto E, Almeida RR, Campos MA, Lima GK, Ferreira LC.

PLoS One. 2013 Aug 8;8(8):e71322. doi: 10.1371/journal.pone.0071322. eCollection 2013.


Protective immunity to DENV2 after immunization with a recombinant NS1 protein using a genetically detoxified heat-labile toxin as an adjuvant.

Amorim JH, Diniz MO, Cariri FA, Rodrigues JF, Bizerra RS, Gonçalves AJ, de Barcelos Alves AM, de Souza Ferreira LC.

Vaccine. 2012 Jan 20;30(5):837-45. doi: 10.1016/j.vaccine.2011.12.034. Epub 2011 Dec 15.


Purified herpes simplex type 1 glycoprotein D (gD) genetically fused with the type 16 human papillomavirus E7 oncoprotein enhances antigen-specific CD8+ T cell responses and confers protective antitumor immunity.

Porchia BF, Diniz MO, Cariri FA, Santana VC, Amorim JH, Balan A, Braga CJ, Ferreira LC.

Mol Pharm. 2011 Dec 5;8(6):2320-30. doi: 10.1021/mp200194s. Epub 2011 Oct 19.


Immune responses and therapeutic antitumor effects of an experimental DNA vaccine encoding human papillomavirus type 16 oncoproteins genetically fused to herpesvirus glycoprotein D.

Diniz MO, Lasaro MO, Ertl HC, Ferreira LC.

Clin Vaccine Immunol. 2010 Oct;17(10):1576-83. doi: 10.1128/CVI.00264-10. Epub 2010 Aug 25.


Anti-tumor DNA vaccines based on the expression of human papillomavirus-16 E6/E7 oncoproteins genetically fused with the glycoprotein D from herpes simplex virus-1.

Lasaro MO, Diniz MO, Reyes-Sandoval A, Ertl HC, Ferreira LC.

Microbes Infect. 2005 Dec;7(15):1541-50. Epub 2005 Sep 9.


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