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Items: 1 to 50 of 51

1.

Clostridium difficile trehalose metabolism variants are common and not associated with adverse patient outcomes when variably present in the same lineage.

Eyre DW, Didelot X, Buckley AM, Freeman J, Moura IB, Crook DW, Peto TEA, Walker AS, Wilcox MH, Dingle KE.

EBioMedicine. 2019 May;43:347-355. doi: 10.1016/j.ebiom.2019.04.038. Epub 2019 Apr 27.

2.

A Role for Tetracycline Selection in Recent Evolution of Agriculture-Associated Clostridium difficile PCR Ribotype 078.

Dingle KE, Didelot X, Quan TP, Eyre DW, Stoesser N, Marwick CA, Coia J, Brown D, Buchanan S, Ijaz UZ, Goswami C, Douce G, Fawley WN, Wilcox MH, Peto TEA, Walker AS, Crook DW.

MBio. 2019 Mar 12;10(2). pii: e02790-18. doi: 10.1128/mBio.02790-18.

3.

Two Distinct Patterns of Clostridium difficile Diversity Across Europe Indicating Contrasting Routes of Spread.

Eyre DW, Davies KA, Davis G, Fawley WN, Dingle KE, De Maio N, Karas A, Crook DW, Peto TEA, Walker AS, Wilcox MH; EUCLID Study Group .

Clin Infect Dis. 2018 Sep 14;67(7):1035-1044. doi: 10.1093/cid/ciy252.

4.

Epidemiology of Clostridium difficile in infants in Oxfordshire, UK: Risk factors for colonization and carriage, and genetic overlap with regional C. difficile infection strains.

Stoesser N, Eyre DW, Quan TP, Godwin H, Pill G, Mbuvi E, Vaughan A, Griffiths D, Martin J, Fawley W, Dingle KE, Oakley S, Wanelik K, Finney JM, Kachrimanidou M, Moore CE, Gorbach S, Riley TV, Crook DW, Peto TEA, Wilcox MH, Walker AS; Modernising Medical Microbiology Informatics Group (MMMIG).

PLoS One. 2017 Aug 16;12(8):e0182307. doi: 10.1371/journal.pone.0182307. eCollection 2017.

5.

Clostridium difficile in England: can we stop washing our hands? - Authors' reply.

Eyre DW, Dingle KE, Didelot X, Quan TP, Peto TEA, Wilcox MH, Walker AS, Crook DW.

Lancet Infect Dis. 2017 May;17(5):478-479. doi: 10.1016/S1473-3099(17)30185-8. No abstract available.

6.

Effects of control interventions on Clostridium difficile infection in England: an observational study.

Dingle KE, Didelot X, Quan TP, Eyre DW, Stoesser N, Golubchik T, Harding RM, Wilson DJ, Griffiths D, Vaughan A, Finney JM, Wyllie DH, Oakley SJ, Fawley WN, Freeman J, Morris K, Martin J, Howard P, Gorbach S, Goldstein EJC, Citron DM, Hopkins S, Hope R, Johnson AP, Wilcox MH, Peto TEA, Walker AS, Crook DW; Modernising Medical Microbiology Informatics Group.

Lancet Infect Dis. 2017 Apr;17(4):411-421. doi: 10.1016/S1473-3099(16)30514-X. Epub 2017 Jan 25.

7.

Detection of a cfr(B) Variant in German Enterococcus faecium Clinical Isolates and the Impact on Linezolid Resistance in Enterococcus spp.

Bender JK, Fleige C, Klare I, Fiedler S, Mischnik A, Mutters NT, Dingle KE, Werner G.

PLoS One. 2016 Nov 28;11(11):e0167042. doi: 10.1371/journal.pone.0167042. eCollection 2016.

8.

Wild bird-associated Campylobacter jejuni isolates are a consistent source of human disease, in Oxfordshire, United Kingdom.

Cody AJ, McCarthy ND, Bray JE, Wimalarathna HM, Colles FM, Jansen van Rensburg MJ, Dingle KE, Waldenström J, Maiden MC.

Environ Microbiol Rep. 2015 Oct;7(5):782-8. doi: 10.1111/1758-2229.12314. Epub 2015 Sep 8.

9.

Emergence and spread of predominantly community-onset Clostridium difficile PCR ribotype 244 infection in Australia, 2010 to 2012.

Eyre DW, Tracey L, Elliott B, Slimings C, Huntington PG, Stuart RL, Korman TM, Kotsiou G, McCann R, Griffiths D, Fawley WN, Armstrong P, Dingle KE, Walker AS, Peto TE, Crook DW, Wilcox MH, Riley TV.

Euro Surveill. 2015 Mar 12;20(10):21059.

10.

The complexity and diversity of the Pathogenicity Locus in Clostridium difficile clade 5.

Elliott B, Dingle KE, Didelot X, Crook DW, Riley TV.

Genome Biol Evol. 2014 Nov 8;6(12):3159-70. doi: 10.1093/gbe/evu248.

11.

Can rapid integrated polymerase chain reaction-based diagnostics for gastrointestinal pathogens improve routine hospital infection control practice? A diagnostic study.

Pankhurst L, Macfarlane-Smith L, Buchanan J, Anson L, Davies K, O'Connor L, Ashwin H, Pike G, Dingle KE, Peto TE, Wordsworth S, Walker AS, Wilcox MH, Crook DW.

Health Technol Assess. 2014 Aug;18(53):1-167. doi: 10.3310/hta18530.

12.

Evolutionary history of the Clostridium difficile pathogenicity locus.

Dingle KE, Elliott B, Robinson E, Griffiths D, Eyre DW, Stoesser N, Vaughan A, Golubchik T, Fawley WN, Wilcox MH, Peto TE, Walker AS, Riley TV, Crook DW, Didelot X.

Genome Biol Evol. 2014 Jan;6(1):36-52. doi: 10.1093/gbe/evt204.

13.

Whole genome sequencing and de novo assembly identifies Sydney-like variant noroviruses and recombinants during the winter 2012/2013 outbreak in England.

Wong TH, Dearlove BL, Hedge J, Giess AP, Piazza P, Trebes A, Paul J, Smit E, Smith EG, Sutton JK, Wilcox MH, Dingle KE, Peto TE, Crook DW, Wilson DJ, Wyllie DH.

Virol J. 2013 Nov 13;10:335. doi: 10.1186/1743-422X-10-335.

14.

Diverse sources of C. difficile infection identified on whole-genome sequencing.

Eyre DW, Cule ML, Wilson DJ, Griffiths D, Vaughan A, O'Connor L, Ip CLC, Golubchik T, Batty EM, Finney JM, Wyllie DH, Didelot X, Piazza P, Bowden R, Dingle KE, Harding RM, Crook DW, Wilcox MH, Peto TEA, Walker AS.

N Engl J Med. 2013 Sep 26;369(13):1195-205. doi: 10.1056/NEJMoa1216064.

15.

A modified RNA-Seq approach for whole genome sequencing of RNA viruses from faecal and blood samples.

Batty EM, Wong TH, Trebes A, Argoud K, Attar M, Buck D, Ip CL, Golubchik T, Cule M, Bowden R, Manganis C, Klenerman P, Barnes E, Walker AS, Wyllie DH, Wilson DJ, Dingle KE, Peto TE, Crook DW, Piazza P.

PLoS One. 2013 Jun 10;8(6):e66129. doi: 10.1371/journal.pone.0066129. Print 2013.

16.

Real-time genomic epidemiological evaluation of human Campylobacter isolates by use of whole-genome multilocus sequence typing.

Cody AJ, McCarthy ND, Jansen van Rensburg M, Isinkaye T, Bentley SD, Parkhill J, Dingle KE, Bowler IC, Jolley KA, Maiden MC.

J Clin Microbiol. 2013 Aug;51(8):2526-34. doi: 10.1128/JCM.00066-13. Epub 2013 May 22.

17.

Relationship between bacterial strain type, host biomarkers, and mortality in Clostridium difficile infection.

Walker AS, Eyre DW, Wyllie DH, Dingle KE, Griffiths D, Shine B, Oakley S, O'Connor L, Finney J, Vaughan A, Crook DW, Wilcox MH, Peto TE; Infections in Oxfordshire Research Database.

Clin Infect Dis. 2013 Jun;56(11):1589-600. doi: 10.1093/cid/cit127. Epub 2013 Mar 5.

18.

Microevolutionary analysis of Clostridium difficile genomes to investigate transmission.

Didelot X, Eyre DW, Cule M, Ip CL, Ansari MA, Griffiths D, Vaughan A, O'Connor L, Golubchik T, Batty EM, Piazza P, Wilson DJ, Bowden R, Donnelly PJ, Dingle KE, Wilcox M, Walker AS, Crook DW, Peto TE, Harding RM.

Genome Biol. 2012 Dec 21;13(12):R118. doi: 10.1186/gb-2012-13-12-r118.

19.

Recombinational switching of the Clostridium difficile S-layer and a novel glycosylation gene cluster revealed by large-scale whole-genome sequencing.

Dingle KE, Didelot X, Ansari MA, Eyre DW, Vaughan A, Griffiths D, Ip CL, Batty EM, Golubchik T, Bowden R, Jolley KA, Hood DW, Fawley WN, Walker AS, Peto TE, Wilcox MH, Crook DW.

J Infect Dis. 2013 Feb 15;207(4):675-86. doi: 10.1093/infdis/jis734. Epub 2012 Nov 29.

20.

Predictors of first recurrence of Clostridium difficile infection: implications for initial management.

Eyre DW, Walker AS, Wyllie D, Dingle KE, Griffiths D, Finney J, O'Connor L, Vaughan A, Crook DW, Wilcox MH, Peto TE; Infections in Oxfordshire Research Database.

Clin Infect Dis. 2012 Aug;55 Suppl 2:S77-87. doi: 10.1093/cid/cis356.

21.

A longitudinal 6-year study of the molecular epidemiology of clinical campylobacter isolates in Oxfordshire, United kingdom.

Cody AJ, McCarthy NM, Wimalarathna HL, Colles FM, Clark L, Bowler IC, Maiden MC, Dingle KE.

J Clin Microbiol. 2012 Oct;50(10):3193-201. doi: 10.1128/JCM.01086-12. Epub 2012 Jul 18.

22.

Macro and micro diversity of Clostridium difficile isolates from diverse sources and geographical locations.

Stabler RA, Dawson LF, Valiente E, Cairns MD, Martin MJ, Donahue EH, Riley TV, Songer JG, Kuijper EJ, Dingle KE, Wren BW.

PLoS One. 2012;7(3):e31559. doi: 10.1371/journal.pone.0031559. Epub 2012 Mar 2.

23.

Characterisation of Clostridium difficile hospital ward-based transmission using extensive epidemiological data and molecular typing.

Walker AS, Eyre DW, Wyllie DH, Dingle KE, Harding RM, O'Connor L, Griffiths D, Vaughan A, Finney J, Wilcox MH, Crook DW, Peto TE.

PLoS Med. 2012 Feb;9(2):e1001172. doi: 10.1371/journal.pmed.1001172. Epub 2012 Feb 7.

24.

Clostridium difficile mixed infection and reinfection.

Eyre DW, Walker AS, Griffiths D, Wilcox MH, Wyllie DH, Dingle KE, Crook DW, Peto TE.

J Clin Microbiol. 2012 Jan;50(1):142-4. doi: 10.1128/JCM.05177-11. Epub 2011 Nov 9.

25.

Molecular epidemiology of Clostridium difficile strains in children compared with that of strains circulating in adults with Clostridium difficile-associated infection.

Stoesser N, Crook DW, Fung R, Griffiths D, Harding RM, Kachrimanidou M, Keshav S, Peto TE, Vaughan A, Walker AS, Dingle KE.

J Clin Microbiol. 2011 Nov;49(11):3994-6. doi: 10.1128/JCM.05349-11. Epub 2011 Sep 21.

26.

Clinical Clostridium difficile: clonality and pathogenicity locus diversity.

Dingle KE, Griffiths D, Didelot X, Evans J, Vaughan A, Kachrimanidou M, Stoesser N, Jolley KA, Golubchik T, Harding RM, Peto TE, Fawley W, Walker AS, Wilcox M, Crook DW.

PLoS One. 2011;6(5):e19993. doi: 10.1371/journal.pone.0019993. Epub 2011 May 19.

27.

Ciprofloxacin-resistant campylobacteriosis in the UK.

Cody AJ, Clarke L, Bowler IC, Dingle KE.

Lancet. 2010 Dec 11;376(9757):1987. doi: 10.1016/S0140-6736(10)62261-1. No abstract available.

PMID:
21146103
28.

Genetic relationships among reptilian and mammalian Campylobacter fetus strains determined by multilocus sequence typing.

Dingle KE, Blaser MJ, Tu ZC, Pruckler J, Fitzgerald C, van Bergen MA, Lawson AJ, Owen RJ, Wagenaar JA.

J Clin Microbiol. 2010 Mar;48(3):977-80. doi: 10.1128/JCM.01439-09. Epub 2010 Jan 6.

29.

Multilocus sequence typing of Clostridium difficile.

Griffiths D, Fawley W, Kachrimanidou M, Bowden R, Crook DW, Fung R, Golubchik T, Harding RM, Jeffery KJ, Jolley KA, Kirton R, Peto TE, Rees G, Stoesser N, Vaughan A, Walker AS, Young BC, Wilcox M, Dingle KE.

J Clin Microbiol. 2010 Mar;48(3):770-8. doi: 10.1128/JCM.01796-09. Epub 2009 Dec 30.

30.

Typing of Campylobacter jejuni isolates from dogs by use of multilocus sequence typing and pulsed-field gel electrophoresis.

Parsons BN, Cody AJ, Porter CJ, Stavisky JH, Smith JL, Williams NJ, Leatherbarrow AJ, Hart CA, Gaskell RM, Dingle KE, Dawson S.

J Clin Microbiol. 2009 Nov;47(11):3466-71. doi: 10.1128/JCM.01046-09. Epub 2009 Sep 30.

31.

Genetic diversity and stability of the porA allele as a genetic marker in human Campylobacter infection.

Cody AJ, Maiden MJ, Dingle KE.

Microbiology. 2009 Dec;155(Pt 12):4145-54. doi: 10.1099/mic.0.031047-0. Epub 2009 Sep 10.

32.

Extended sequence typing of Campylobacter spp., United Kingdom.

Dingle KE, McCarthy ND, Cody AJ, Peto TE, Maiden MC.

Emerg Infect Dis. 2008 Oct;14(10):1620-2. doi: 10.3201/eid1410.071109.

33.

Campylobacter infection of broiler chickens in a free-range environment.

Colles FM, Jones TA, McCarthy ND, Sheppard SK, Cody AJ, Dingle KE, Dawkins MS, Maiden MC.

Environ Microbiol. 2008 Aug;10(8):2042-50. doi: 10.1111/j.1462-2920.2008.01623.x. Epub 2008 Apr 10.

34.

Comparison of Campylobacter populations in wild geese with those in starlings and free-range poultry on the same farm.

Colles FM, Dingle KE, Cody AJ, Maiden MC.

Appl Environ Microbiol. 2008 Jun;74(11):3583-90. doi: 10.1128/AEM.02491-07. Epub 2008 Apr 4.

35.

Use of multilocus sequence typing to investigate the association between the presence of Campylobacter spp. in broiler drinking water and Campylobacter colonization in broilers.

Ogden ID, MacRae M, Johnston M, Strachan NJ, Cody AJ, Dingle KE, Newell DG.

Appl Environ Microbiol. 2007 Aug;73(16):5125-9. Epub 2007 Jun 22.

36.

Host-associated genetic import in Campylobacter jejuni.

McCarthy ND, Colles FM, Dingle KE, Bagnall MC, Manning G, Maiden MC, Falush D.

Emerg Infect Dis. 2007 Feb;13(2):267-72.

37.

Multilocus sequence typing of Campylobacter jejuni isolates from New South Wales, Australia.

Mickan L, Doyle R, Valcanis M, Dingle KE, Unicomb L, Lanser J; Australian Campylobacter Subtyping Study Group.

J Appl Microbiol. 2007 Jan;102(1):144-52.

38.

Clonal nature of Campylobacter fetus as defined by multilocus sequence typing.

van Bergen MA, Dingle KE, Maiden MC, Newell DG, van der Graaf-Van Bloois L, van Putten JP, Wagenaar JA.

J Clin Microbiol. 2005 Dec;43(12):5888-98.

39.

Ciprofloxacin resistance among human Campylobacter isolates 1991-2004: an update.

Dingle KE, Clarke L, Bowler IC.

J Antimicrob Chemother. 2005 Aug;56(2):435-7. Epub 2005 Jun 14. No abstract available.

PMID:
15956098
40.

Sequence typing and comparison of population biology of Campylobacter coli and Campylobacter jejuni.

Dingle KE, Colles FM, Falush D, Maiden MC.

J Clin Microbiol. 2005 Jan;43(1):340-7.

41.

Mutation in a Lordsdale norovirus epidemic strain as a potential indicator of transmission routes.

Dingle KE; Norovirus Infection Control in Oxfordshire Communities Hospitals.

J Clin Microbiol. 2004 Sep;42(9):3950-7.

42.
43.

Molecular evidence for dissemination of unique Campylobacter jejuni clones in Curaçao, Netherlands Antilles.

Duim B, Godschalk PC, van den Braak N, Dingle KE, Dijkstra JR, Leyde E, van der Plas J, Colles FM, Endtz HP, Wagenaar JA, Maiden MC, van Belkum A.

J Clin Microbiol. 2003 Dec;41(12):5593-7.

44.

Reference isolates for the clonal complexes of Campylobacter jejuni.

Wareing DR, Ure R, Colles FM, Bolton FJ, Fox AJ, Maiden MC, Dingle KE.

Lett Appl Microbiol. 2003;36(2):106-10.

45.
46.

Molecular characterization of Campylobacter jejuni clones: a basis for epidemiologic investigation.

Dingle KE, Colles FM, Ure R, Wagenaar JA, Duim B, Bolton FJ, Fox AJ, Wareing DR, Maiden MC.

Emerg Infect Dis. 2002 Sep;8(9):949-55.

47.

Sequence typing confirms that Campylobacter jejuni strains associated with Guillain-Barré and Miller-Fisher syndromes are of diverse genetic lineage, serotype, and flagella type.

Dingle KE, Van Den Braak N, Colles FM, Price LJ, Woodward DL, Rodgers FG, Endtz HP, Van Belkum A, Maiden MC.

J Clin Microbiol. 2001 Sep;39(9):3346-9.

48.

Multilocus sequence typing system for Campylobacter jejuni.

Dingle KE, Colles FM, Wareing DR, Ure R, Fox AJ, Bolton FE, Bootsma HJ, Willems RJ, Urwin R, Maiden MC.

J Clin Microbiol. 2001 Jan;39(1):14-23.

49.
50.

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