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Items: 16

1.

P2Y6 receptor potentiates pro-inflammatory responses in macrophages and exhibits differential roles in atherosclerotic lesion development.

Garcia RA, Yan M, Search D, Zhang R, Carson NL, Ryan CS, Smith-Monroy C, Zheng J, Chen J, Kong Y, Tang H, Hellings SE, Wardwell-Swanson J, Dinchuk JE, Psaltis GC, Gordon DA, Glunz PW, Gargalovic PS.

PLoS One. 2014 Oct 31;9(10):e111385. doi: 10.1371/journal.pone.0111385. eCollection 2014.

2.

Drug safety is a barrier to the discovery and development of new androgen receptor antagonists.

Foster WR, Car BD, Shi H, Levesque PC, Obermeier MT, Gan J, Arezzo JC, Powlin SS, Dinchuk JE, Balog A, Salvati ME, Attar RM, Gottardis MM.

Prostate. 2011 Apr;71(5):480-8. doi: 10.1002/pros.21263. Epub 2010 Sep 28.

PMID:
20878947
3.

Insulin receptor (IR) pathway hyperactivity in IGF-IR null cells and suppression of downstream growth signaling using the dual IGF-IR/IR inhibitor, BMS-754807.

Dinchuk JE, Cao C, Huang F, Reeves KA, Wang J, Myers F, Cantor GH, Zhou X, Attar RM, Gottardis M, Carboni JM.

Endocrinology. 2010 Sep;151(9):4123-32. doi: 10.1210/en.2010-0032. Epub 2010 Jul 7.

PMID:
20610571
4.

Evaluation of cynomolgus monkey pregnane X receptor, primary hepatocyte, and in vivo pharmacokinetic changes in predicting human CYP3A4 induction.

Kim S, Dinchuk JE, Anthony MN, Orcutt T, Zoeckler ME, Sauer MB, Mosure KW, Vuppugalla R, Grace JE Jr, Simmermacher J, Dulac HA, Pizzano J, Sinz M.

Drug Metab Dispos. 2010 Jan;38(1):16-24. doi: 10.1124/dmd.109.029637.

PMID:
19833845
5.

COX-3: in the wrong frame in mind.

Dinchuk JE, Liu RQ, Trzaskos JM.

Immunol Lett. 2003 Mar 3;86(1):121. No abstract available.

PMID:
12600754
6.

Antisense oligonucleotides selectively regulate aspartyl beta-hydroxylase and its truncated protein isoform in vitro but distribute poorly into A549 tumors in vivo.

Ho SP, Scully MS, Krauthauser CM, Wexler EJ, Stow MD, Dinchuk JE, Kerr JS, Friedman PA.

J Pharmacol Exp Ther. 2002 Aug;302(2):795-803.

PMID:
12130746
7.

Absence of post-translational aspartyl beta-hydroxylation of epidermal growth factor domains in mice leads to developmental defects and an increased incidence of intestinal neoplasia.

Dinchuk JE, Focht RJ, Kelley JA, Henderson NL, Zolotarjova NI, Wynn R, Neff NT, Link J, Huber RM, Burn TC, Rupar MJ, Cunningham MR, Selling BH, Ma J, Stern AA, Hollis GF, Stein RB, Friedman PA.

J Biol Chem. 2002 Apr 12;277(15):12970-7. Epub 2001 Dec 31.

8.

Aspartyl beta -hydroxylase (Asph) and an evolutionarily conserved isoform of Asph missing the catalytic domain share exons with junctin.

Dinchuk JE, Henderson NL, Burn TC, Huber R, Ho SP, Link J, O'Neil KT, Focht RJ, Scully MS, Hollis JM, Hollis GF, Friedman PA.

J Biol Chem. 2000 Dec 15;275(50):39543-54.

9.

Cyclooxygenase-2 is essential for normal recovery from 5-fluorouracil-induced myelotoxicity in mice.

Lorenz M, Slaughter HS, Wescott DM, Carter SI, Schnyder B, Dinchuk JE, Car BD.

Exp Hematol. 1999 Oct;27(10):1494-502.

PMID:
10517490
10.

Multiple female reproductive failures in cyclooxygenase 2-deficient mice.

Lim H, Paria BC, Das SK, Dinchuk JE, Langenbach R, Trzaskos JM, Dey SK.

Cell. 1997 Oct 17;91(2):197-208.

11.

Suppression of intestinal polyposis in Apc delta716 knockout mice by inhibition of cyclooxygenase 2 (COX-2).

Oshima M, Dinchuk JE, Kargman SL, Oshima H, Hancock B, Kwong E, Trzaskos JM, Evans JF, Taketo MM.

Cell. 1996 Nov 29;87(5):803-9.

12.

Renal abnormalities and an altered inflammatory response in mice lacking cyclooxygenase II.

Dinchuk JE, Car BD, Focht RJ, Johnston JJ, Jaffee BD, Covington MB, Contel NR, Eng VM, Collins RJ, Czerniak PM, et al.

Nature. 1995 Nov 23;378(6555):406-9.

PMID:
7477380
13.

Fluorescence in situ hybridization of interphase nuclei isolated from whole blood of transgenic mice.

Dinchuk JE, Kelley K, Boyle AL.

Biotechniques. 1994 Nov;17(5):954-61.

PMID:
7840978
14.

Flow cytometric analysis of transport activity in lymphocytes electroporated with a fluorescent organic anion dye.

Dinchuk JE, Kelley KA, Callahan GN.

J Immunol Methods. 1992 Nov 5;155(2):257-65.

PMID:
1431154
15.
16.

Effects of estramustine and megestrol on ultrastructure of rat ventral prostate.

Dinchuk JE, Chai LS, Karr JP, Murphy GP, Sandberg AA.

Urology. 1982 May;19(5):511-22.

PMID:
7080325

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