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Items: 1 to 50 of 64

1.

Timosaponin A-III inhibits oncogenic phenotype via regulation of PcG protein BMI1 in breast cancer cells.

Gergely JE, Dorsey AE, Dimri GP, Dimri M.

Mol Carcinog. 2018 Jul;57(7):831-841. doi: 10.1002/mc.22804. Epub 2018 Mar 25.

2.

CBX7 regulates stem cell-like properties of gastric cancer cells via p16 and AKT-NF-κB-miR-21 pathways.

Ni SJ, Zhao LQ, Wang XF, Wu ZH, Hua RX, Wan CH, Zhang JY, Zhang XW, Huang MZ, Gan L, Sun HL, Dimri GP, Guo WJ.

J Hematol Oncol. 2018 Feb 8;11(1):17. doi: 10.1186/s13045-018-0562-z.

3.

A miR-200c/141-BMI1 autoregulatory loop regulates oncogenic activity of BMI1 in cancer cells.

Dimri M, Kang M, Dimri GP.

Oncotarget. 2016 Jun 14;7(24):36220-36234. doi: 10.18632/oncotarget.8811.

4.

MicroRNA-31 is a transcriptional target of histone deacetylase inhibitors and a regulator of cellular senescence.

Cho JH, Dimri M, Dimri GP.

J Biol Chem. 2015 Apr 17;290(16):10555-67. doi: 10.1074/jbc.M114.624361. Epub 2015 Mar 3.

5.

PLK1 inhibition down-regulates polycomb group protein BMI1 via modulation of the miR-200c/141 cluster.

Dimri M, Cho JH, Kang M, Dimri GP.

J Biol Chem. 2015 Jan 30;290(5):3033-44. doi: 10.1074/jbc.M114.615179. Epub 2014 Dec 12.

6.

UBTD1 induces cellular senescence through an UBTD1-Mdm2/p53 positive feedback loop.

Zhang XW, Wang XF, Ni SJ, Qin W, Zhao LQ, Hua RX, Lu YW, Li J, Dimri GP, Guo WJ.

J Pathol. 2015 Mar;235(4):656-67. doi: 10.1002/path.4478. Epub 2015 Jan 7.

PMID:
25382750
7.

microRNA-141 regulates BMI1 expression and induces senescence in human diploid fibroblasts.

Dimri M, Carroll JD, Cho JH, Dimri GP.

Cell Cycle. 2013 Nov 15;12(22):3537-46. doi: 10.4161/cc.26592. Epub 2013 Sep 24.

8.

Colorimetric detection of senescence-associated β galactosidase.

Itahana K, Itahana Y, Dimri GP.

Methods Mol Biol. 2013;965:143-56. doi: 10.1007/978-1-62703-239-1_8.

9.

A positive feedback loop regulates the expression of polycomb group protein BMI1 via WNT signaling pathway.

Cho JH, Dimri M, Dimri GP.

J Biol Chem. 2013 Feb 1;288(5):3406-18. doi: 10.1074/jbc.M112.422931. Epub 2012 Dec 13.

10.

pRb or its cousins: who controls the family business?

Itahana K, Dimri GP.

Cell Cycle. 2012 Apr 15;11(8):1486. doi: 10.4161/cc.20048. No abstract available.

11.

Can BMI-1 be a biomarker of poor prognosis?

Itahana K, Dimri GP.

Epigenomics. 2010 Oct;2(5):609-10. doi: 10.2217/epi.10.52. No abstract available.

12.

βTrCP regulates BMI1 protein turnover via ubiquitination and degradation.

Sahasrabuddhe AA, Dimri M, Bommi PV, Dimri GP.

Cell Cycle. 2011 Apr 15;10(8):1322-30. Epub 2011 Apr 15.

13.

Could BMI-1 siRNA be a promising tool for cancer therapy?

Itahana K, Dimri GP.

Epigenomics. 2010 Oct;2(5):611. No abstract available.

PMID:
22232789
14.

A direct link between MYCN and BMI-1 in neuroblastoma.

Itahana K, Dimri GP.

Epigenomics. 2010 Oct;2(5):610. No abstract available.

PMID:
22232788
15.

Deletion analysis of BMI1 oncoprotein identifies its negative regulatory domain.

Yadav AK, Sahasrabuddhe AA, Dimri M, Bommi PV, Sainger R, Dimri GP.

Mol Cancer. 2010 Jun 22;9:158. doi: 10.1186/1476-4598-9-158.

16.

The polycomb group protein BMI1 is a transcriptional target of HDAC inhibitors.

Bommi PV, Dimri M, Sahasrabuddhe AA, Khandekar J, Dimri GP.

Cell Cycle. 2010 Jul 1;9(13):2663-73.

17.

BMI1 and Mel-18 oppositely regulate carcinogenesis and progression of gastric cancer.

Zhang XW, Sheng YP, Li Q, Qin W, Lu YW, Cheng YF, Liu BY, Zhang FC, Li J, Dimri GP, Guo WJ.

Mol Cancer. 2010 Feb 21;9:40. doi: 10.1186/1476-4598-9-40.

18.

Dietary omega-3 polyunsaturated fatty acids suppress expression of EZH2 in breast cancer cells.

Dimri M, Bommi PV, Sahasrabuddhe AA, Khandekar JD, Dimri GP.

Carcinogenesis. 2010 Mar;31(3):489-95. doi: 10.1093/carcin/bgp305. Epub 2009 Dec 7.

19.

Bmi1 functions as an oncogene independent of Ink4A/Arf repression in hepatic carcinogenesis.

Xu CR, Lee S, Ho C, Bommi P, Huang SA, Cheung ST, Dimri GP, Chen X.

Mol Cancer Res. 2009 Dec;7(12):1937-45. doi: 10.1158/1541-7786.MCR-09-0333. Epub 2009 Nov 24.

20.

c-Myc and telomerase activation.

Dimri GP.

Cell Cycle. 2009 Oct 1;8(19):3075-6. Epub 2009 Oct 1. No abstract available.

PMID:
19770580
21.

BMI1 cooperates with H-RAS to induce an aggressive breast cancer phenotype with brain metastases.

Hoenerhoff MJ, Chu I, Barkan D, Liu ZY, Datta S, Dimri GP, Green JE.

Oncogene. 2009 Aug 27;28(34):3022-32. doi: 10.1038/onc.2009.165. Epub 2009 Jun 22.

22.

Hyperoxia-induced premature senescence requires p53 and pRb, but not mitochondrial matrix ROS.

Klimova TA, Bell EL, Shroff EH, Weinberg FD, Snyder CM, Dimri GP, Schumacker PT, Budinger GR, Chandel NS.

FASEB J. 2009 Mar;23(3):783-94. doi: 10.1096/fj.08-114256. Epub 2008 Oct 23.

23.

FoxM1c counteracts oxidative stress-induced senescence and stimulates Bmi-1 expression.

Li SK, Smith DK, Leung WY, Cheung AM, Lam EW, Dimri GP, Yao KM.

J Biol Chem. 2008 Jun 13;283(24):16545-53. doi: 10.1074/jbc.M709604200. Epub 2008 Apr 11.

24.

In search of breast cancer culprits: suspecting the suspected and the unsuspected.

Dimri GP.

Breast Cancer (Auckl). 2008;1:1-5. Epub 2008 Jan 15.

25.

Bmi-1 cooperates with H-Ras to transform human mammary epithelial cells via dysregulation of multiple growth-regulatory pathways.

Datta S, Hoenerhoff MJ, Bommi P, Sainger R, Guo WJ, Dimri M, Band H, Band V, Green JE, Dimri GP.

Cancer Res. 2007 Nov 1;67(21):10286-95.

26.

Methods to detect biomarkers of cellular senescence: the senescence-associated beta-galactosidase assay.

Itahana K, Campisi J, Dimri GP.

Methods Mol Biol. 2007;371:21-31. Review.

PMID:
17634571
27.

Expression of Bmi-1 in epidermis enhances cell survival by altering cell cycle regulatory protein expression and inhibiting apoptosis.

Lee K, Adhikary G, Balasubramanian S, Gopalakrishnan R, McCormick T, Dimri GP, Eckert RL, Rorke EA.

J Invest Dermatol. 2008 Jan;128(1):9-17. Epub 2007 Jul 12.

28.

Mel-18 acts as a tumor suppressor by repressing Bmi-1 expression and down-regulating Akt activity in breast cancer cells.

Guo WJ, Zeng MS, Yadav A, Song LB, Guo BH, Band V, Dimri GP.

Cancer Res. 2007 Jun 1;67(11):5083-9.

29.

Modeling breast cancer-associated c-Src and EGFR overexpression in human MECs: c-Src and EGFR cooperatively promote aberrant three-dimensional acinar structure and invasive behavior.

Dimri M, Naramura M, Duan L, Chen J, Ortega-Cava C, Chen G, Goswami R, Fernandes N, Gao Q, Dimri GP, Band V, Band H.

Cancer Res. 2007 May 1;67(9):4164-72.

30.

Elevated Bmi-1 expression is associated with dysplastic cell transformation during oral carcinogenesis and is required for cancer cell replication and survival.

Kang MK, Kim RH, Kim SJ, Yip FK, Shin KH, Dimri GP, Christensen R, Han T, Park NH.

Br J Cancer. 2007 Jan 15;96(1):126-33. Epub 2006 Dec 19.

31.
32.

Bmi-1 is a novel molecular marker of nasopharyngeal carcinoma progression and immortalizes primary human nasopharyngeal epithelial cells.

Song LB, Zeng MS, Liao WT, Zhang L, Mo HY, Liu WL, Shao JY, Wu QL, Li MZ, Xia YF, Fu LW, Huang WL, Dimri GP, Band V, Zeng YX.

Cancer Res. 2006 Jun 15;66(12):6225-32.

33.

What has senescence got to do with cancer?

Dimri GP.

Cancer Cell. 2005 Jun;7(6):505-12. Review.

34.

The search for biomarkers of aging: next stop INK4a/ARF locus.

Dimri GP.

Sci Aging Knowledge Environ. 2004 Nov 3;2004(44):pe40. Review.

PMID:
15525836
35.

Mechanisms of cellular senescence in human and mouse cells.

Itahana K, Campisi J, Dimri GP.

Biogerontology. 2004;5(1):1-10. Review.

PMID:
15138376
36.

Control of the replicative life span of human fibroblasts by p16 and the polycomb protein Bmi-1.

Itahana K, Zou Y, Itahana Y, Martinez JL, Beausejour C, Jacobs JJ, Van Lohuizen M, Band V, Campisi J, Dimri GP.

Mol Cell Biol. 2003 Jan;23(1):389-401.

37.

The Bmi-1 oncogene induces telomerase activity and immortalizes human mammary epithelial cells.

Dimri GP, Martinez JL, Jacobs JJ, Keblusek P, Itahana K, Van Lohuizen M, Campisi J, Wazer DE, Band V.

Cancer Res. 2002 Aug 15;62(16):4736-45.

38.

A role for p53 in maintaining and establishing the quiescence growth arrest in human cells.

Itahana K, Dimri GP, Hara E, Itahana Y, Zou Y, Desprez PY, Campisi J.

J Biol Chem. 2002 May 17;277(20):18206-14. Epub 2002 Mar 5.

39.

Effect of time exposure to high altitude on zinc and copper concentrations in human plasma.

Rawal SB, Singh MV, Tyagi AK, Roy J, Dimri GP, Selvamurthy W.

Aviat Space Environ Med. 1999 Dec;70(12):1161-5.

PMID:
10596768
40.
41.
42.
43.

Replicative senescence, aging and growth-regulatory transcription factors.

Dimri GP, Testori A, Acosta M, Campisi J.

Biol Signals. 1996 May-Jun;5(3):154-62.

PMID:
8864060
44.
45.

Coming of age in culture.

Campisi J, Dimri GP, Nehlin JO, Testori A, Yoshimoto K.

Exp Gerontol. 1996 Jan-Apr;31(1-2):7-12. Review.

PMID:
8706807
46.

A biomarker that identifies senescent human cells in culture and in aging skin in vivo.

Dimri GP, Lee X, Basile G, Acosta M, Scott G, Roskelley C, Medrano EE, Linskens M, Rubelj I, Pereira-Smith O, et al.

Proc Natl Acad Sci U S A. 1995 Sep 26;92(20):9363-7.

47.

Regulation of two E2F-related genes in presenescent and senescent human fibroblasts.

Dimri GP, Hara E, Campisi J.

J Biol Chem. 1994 Jun 10;269(23):16180-6.

48.

Altered profile of transcription factor-binding activities in senescent human fibroblasts.

Dimri GP, Campisi J.

Exp Cell Res. 1994 May;212(1):132-40.

PMID:
8174635
49.

Molecular and cell biology of replicative senescence.

Dimri GP, Campisi J.

Cold Spring Harb Symp Quant Biol. 1994;59:67-73. Review. No abstract available.

PMID:
7587128

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