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Creatinine versus cystatin C to estimate glomerular filtration rate in adults with congenital heart disease: Results of the Boston Adult Congenital Heart Disease Biobank.

Opotowsky AR, Carazo M, Singh MN, Dimopoulos K, Cardona-Estrada DA, Elantably A, Waikar SS, Mc Causland FR, Veldtman G, Grewal J, Gray C, Loukas BN, Rajpal S.

Am Heart J. 2019 May 22;214:142-155. doi: 10.1016/j.ahj.2019.04.018. [Epub ahead of print]


Efficacy of catheter ablation for atrial fibrillation in patients with congenital heart disease.

Guarguagli S, Kempny A, Cazzoli I, Barracano R, Gatzoulis MA, Dimopoulos K, Ernst S.

Europace. 2019 Jun 5. pii: euz157. doi: 10.1093/europace/euz157. [Epub ahead of print]


Evaluating a strategy of PAH therapy pre-treatment in patients with atrial septal defects and pulmonary arterial hypertension to permit safe repair ("treat-and-repair").

Constantine A, Dimopoulos K.

Int J Cardiol. 2019 Sep 15;291:142-144. doi: 10.1016/j.ijcard.2019.05.039. Epub 2019 May 20. No abstract available.


Right ventricular systolic to diastolic duration ratio: A novel predictor of outcome in adult idiopathic pulmonary arterial hypertension.

McCabe C, Vranesic II, Verdes MC, Kempny A, Khan U, Price L, Gatzoulis MA, Dimopoulos K, Wort SJ, Li W.

Int J Cardiol. 2019 May 8. pii: S0167-5273(19)31137-4. doi: 10.1016/j.ijcard.2019.05.019. [Epub ahead of print]


Eisenmenger syndrome and other types of pulmonary arterial hypertension related to adult congenital heart disease.

Favoccia C, Constantine AH, Wort SJ, Dimopoulos K.

Expert Rev Cardiovasc Ther. 2019 Jun;17(6):449-459. doi: 10.1080/14779072.2019.1623024. Epub 2019 Jun 6.


Blood Viscosity and its Relevance to the Diagnosis and Management of Pulmonary Hypertension.

Kempny A, Dimopoulos K, Fraisse A, Diller GP, Price LC, Rafiq I, McCabe C, Gatzoulis MA, Wort SJ.

J Am Coll Cardiol. 2019 May 28;73(20):2640-2642. doi: 10.1016/j.jacc.2019.02.066. No abstract available.


Does gender affect the prognosis and risk of complications in patients with congenital heart disease in the modern era?

D'Alto M, Budts W, Diller GP, Mulder B, Egidy Assenza G, Oreto L, Ciliberti P, Bassareo PP, Gatzoulis MA, Dimopoulos K.

Int J Cardiol. 2019 Sep 1;290:156-161. doi: 10.1016/j.ijcard.2019.05.010. Epub 2019 May 4.


Peripartum outcomes in a large population of women with pulmonary arterial hypertension associated with congenital heart disease.

Li Q, Dimopoulos K, Liu T, Xu Z, Liu Q, Li Y, Zhang J, Gu H.

Eur J Prev Cardiol. 2019 Jul;26(10):1067-1076. doi: 10.1177/2047487318821246. Epub 2019 Apr 11.


Early histological changes of pulmonary arterial hypertension disclosed by invasive cardiopulmonary exercise testing.

Bhatti YJ, Rice AJ, Kempny A, Dimopoulos K, Price LC, Ranu H, Wells A, Wort SJ, McCabe C.

Pulm Circ. 2019 Apr-Jun;9(2):2045894019845615. doi: 10.1177/2045894019845615.


Epigenetic therapy in hematological cancers.

Dimopoulos K, Grønbaek K.

APMIS. 2019 May;127(5):316-328. doi: 10.1111/apm.12906. Epub 2019 Mar 12. Review.


Pulmonary Artery Denervation: A New, Long-Awaited Interventional Treatment for Combined Pre- and Post-Capillary Pulmonary Hypertension?

Dimopoulos K, Ernst S, McCabe C, Kempny A.

JACC Cardiovasc Interv. 2019 Feb 11;12(3):285-288. doi: 10.1016/j.jcin.2018.10.045. No abstract available.


Surgical and percutaneous pulmonary valve replacement in England over the past two decades.

Larsen SH, Dimopoulos K, Gatzoulis MA, Uebing A, Shore DF, Alonso-Gonzalez R, Kempny A.

Heart. 2019 Jun;105(12):932-937. doi: 10.1136/heartjnl-2018-314102. Epub 2019 Jan 30.


Machine learning algorithms estimating prognosis and guiding therapy in adult congenital heart disease: data from a single tertiary centre including 10 019 patients.

Diller GP, Kempny A, Babu-Narayan SV, Henrichs M, Brida M, Uebing A, Lammers AE, Baumgartner H, Li W, Wort SJ, Dimopoulos K, Gatzoulis MA.

Eur Heart J. 2019 Apr 1;40(13):1069-1077. doi: 10.1093/eurheartj/ehy915.


Heart or heart-lung transplantation for patients with congenital heart disease in England.

Dimopoulos K, Muthiah K, Alonso-Gonzalez R, Banner NR, Wort SJ, Swan L, Constantine AH, Gatzoulis MA, Diller GP, Kempny A.

Heart. 2019 Apr;105(8):596-602. doi: 10.1136/heartjnl-2018-313984. Epub 2019 Jan 12.


Utility of machine learning algorithms in assessing patients with a systemic right ventricle.

Diller GP, Babu-Narayan S, Li W, Radojevic J, Kempny A, Uebing A, Dimopoulos K, Baumgartner H, Gatzoulis MA, Orwat S.

Eur Heart J Cardiovasc Imaging. 2019 Jan 9. doi: 10.1093/ehjci/jey211. [Epub ahead of print]


EmPHasis-10 score for the assessment of quality of life in various types of pulmonary hypertension and its relation to outcome.

Favoccia C, Kempny A, Yorke J, Armstrong I, Price LC, McCabe C, Harries C, Wort SJ, Dimopoulos K.

Eur J Prev Cardiol. 2018 Dec 19:2047487318819161. doi: 10.1177/2047487318819161. [Epub ahead of print] No abstract available.


Risk stratification in congenital heart disease - A call for protocolised assessment and multicentre collaboration.

Kempny A, Fraisse A, Dimopoulos K.

Int J Cardiol. 2019 Feb 1;276:114-115. doi: 10.1016/j.ijcard.2018.11.101. Epub 2018 Nov 20. No abstract available.


Echocardiographic Screening for Pulmonary Hypertension in Congenital Heart Disease: JACC Review Topic of the Week.

Dimopoulos K, Condliffe R, Tulloh RMR, Clift P, Alonso-Gonzalez R, Bedair R, Chung NAY, Coghlan G, Fitzsimmons S, Frigiola A, Howard LS, Jenkins P, Kenny D, Li W, MacDonald ST, McCabe C, Oliver JJ, Spence MS, Szantho GV, von Klemperer K, Wilson DG, Wort SJ; CHAMPION Steering Committee.

J Am Coll Cardiol. 2018 Dec 4;72(22):2778-2788. doi: 10.1016/j.jacc.2018.08.2201. Review.


The outcome of adults born with pulmonary atresia: High morbidity and mortality irrespective of repair.

Montanaro C, Merola A, Kempny A, Alvarez-Alvarez B, Alonso-Gonzalez R, Swan L, Uebing A, Li W, Babu-Narayan SV, Gatzoulis MA, Dimopoulos K.

Int J Cardiol. 2019 Apr 1;280:61-66. doi: 10.1016/j.ijcard.2018.11.011. Epub 2018 Nov 7.


Incidence, mortality and bleeding rates associated with pulmonary embolism in England between 1997 and 2015.

Kempny A, McCabe C, Dimopoulos K, Price LC, Wilde M, Limbrey R, Gatzoulis MA, Wort SJ.

Int J Cardiol. 2019 Feb 15;277:229-234. doi: 10.1016/j.ijcard.2018.10.001. Epub 2018 Oct 2.


Strength training in congenital heart disease: A way to boost respiratory function?

Ntelios D, Giannakoulas G, Dimopoulos K.

Eur J Prev Cardiol. 2019 Mar;26(5):489-491. doi: 10.1177/2047487318812505. Epub 2018 Nov 14. No abstract available.


Atrial septal defects and pulmonary arterial hypertension.

Nashat H, Montanaro C, Li W, Kempny A, Wort SJ, Dimopoulos K, Gatzoulis MA, Babu-Narayan SV.

J Thorac Dis. 2018 Sep;10(Suppl 24):S2953-S2965. doi: 10.21037/jtd.2018.08.92. Review.


Ramipril and left ventricular diastolic function in stable patients with pulmonary regurgitation after repair of tetralogy of Fallot.

Krupickova S, Li W, Cheang MH, Rigby ML, Uebing A, Davlouros P, Dimopoulos K, Di Salvo G, Fraisse A, Swan L, Alonso-Gonzalez R, Kempny A, Pennell DJ, Senior R, Gatzoulis MA, Babu-Narayan SV.

Int J Cardiol. 2018 Dec 1;272:64-69. doi: 10.1016/j.ijcard.2018.07.132. Epub 2018 Aug 1.


Right Atrial Function Predicts Clinical Outcome in Patients with Precapillary Pulmonary Hypertension.

Mouratoglou SA, Dimopoulos K, Kamperidis V, Feloukidis C, Kallifatidis A, Pitsiou G, Stanopoulos I, Grosomanidis V, Hadjimiltiades S, Karvounis H, Giannakoulas G.

J Am Soc Echocardiogr. 2018 Oct;31(10):1137-1145. doi: 10.1016/j.echo.2018.05.015. Epub 2018 Aug 6.


Management dilemmas in pulmonary arterial hypertension associated with congenital heart disease.

Condliffe R, Clift P, Dimopoulos K, Tulloh RMR.

Pulm Circ. 2018 Jul-Sep;8(3):2045894018792501. doi: 10.1177/2045894018792501. Epub 2018 Jul 23.


Definition and Management of Segmental Pulmonary Hypertension.

Dimopoulos K, Diller GP, Opotowsky AR, D'Alto M, Gu H, Giannakoulas G, Budts W, Broberg CS, Veldtman G, Swan L, Beghetti M, Gatzoulis MA.

J Am Heart Assoc. 2018 Jul 4;7(14). pii: e008587. doi: 10.1161/JAHA.118.008587. No abstract available.


Right Heart Catheterization for the Diagnosis of Pulmonary Hypertension: Controversies and Practical Issues.

D'Alto M, Dimopoulos K, Coghlan JG, Kovacs G, Rosenkranz S, Naeije R.

Heart Fail Clin. 2018 Jul;14(3):467-477. doi: 10.1016/j.hfc.2018.03.011. Review.


Use of intravenous iron in cyanotic patients with congenital heart disease and/or pulmonary hypertension.

Blanche C, Alonso-Gonzalez R, Uribarri A, Kempny A, Swan L, Price L, Wort SJ, Beghetti M, Dimopoulos K.

Int J Cardiol. 2018 Sep 15;267:79-83. doi: 10.1016/j.ijcard.2018.05.062. Epub 2018 May 19.


Arrhythmias in adult patients with congenital heart disease and pulmonary arterial hypertension.

Drakopoulou M, Nashat H, Kempny A, Alonso-Gonzalez R, Swan L, Wort SJ, Price LC, McCabe C, Wong T, Gatzoulis MA, Ernst S, Dimopoulos K.

Heart. 2018 Dec;104(23):1963-1969. doi: 10.1136/heartjnl-2017-312881. Epub 2018 May 18.


A stepwise composite echocardiographic score predicts severe pulmonary hypertension in patients with interstitial lung disease.

Bax S, Bredy C, Kempny A, Dimopoulos K, Devaraj A, Walsh S, Jacob J, Nair A, Kokosi M, Keir G, Kouranos V, George PM, McCabe C, Wilde M, Wells A, Li W, Wort SJ, Price LC.

ERJ Open Res. 2018 May 4;4(2). pii: 00124-2017. doi: 10.1183/23120541.00124-2017. eCollection 2018 Apr. Erratum in: ERJ Open Res. 2018 Jul 31;4(3):.


Expression of CRBN, IKZF1, and IKZF3 does not predict lenalidomide sensitivity and mutations in the cereblon pathway are infrequent in multiple myeloma.

Dimopoulos K, Fibiger Munch-Petersen H, Winther Eskelund C, Dissing Sjö L, Ralfkiaer E, Gimsing P, Grønbaek K.

Leuk Lymphoma. 2019 Jan;60(1):180-188. doi: 10.1080/10428194.2018.1466290. Epub 2018 May 2.


Balloon pulmonary angioplasty for chronic thromboembolic disease: aiming for perfection.

Kempny A, Wort SJ, Dimopoulos K.

EuroIntervention. 2018 Apr 20;13(17):1983-1986. doi: 10.4244/EIJV13I17A323. No abstract available.


Intraductal papillary neoplasm of the bile duct : case report and review of the literature.

Apostolopoulos P, Ekmektzoglou KA, Paraskeva K, Dimopoulos K, Paparaskeva K, Alexandrakis G.

Acta Gastroenterol Belg. 2018 Jan-Mar;81(1):97-99. Review.


Acute Effect of Inhaled Iloprost in Children with Pulmonary Arterial Hypertension Associated with Simple Congenital Heart Defects.

Li Q, Dimopoulos K, Zhang C, Zhu Y, Liu Q, Gu H.

Pediatr Cardiol. 2018 Apr;39(4):757-762. doi: 10.1007/s00246-018-1818-7. Epub 2018 Feb 9.


Management of Adults With Congenital Heart Disease and Pulmonary Arterial Hypertension in the UK: Survey of Current Practice, Unmet Needs and Expert Commentary.

Tulloh R, Dimopoulos K, Condliffe R, Clift P; CHAMPION Steering Committee.

Heart Lung Circ. 2018 Aug;27(8):1018-1027. doi: 10.1016/j.hlc.2017.10.018. Epub 2017 Nov 13.


Dual inhibition of DNMTs and EZH2 can overcome both intrinsic and acquired resistance of myeloma cells to IMiDs in a cereblon-independent manner.

Dimopoulos K, Søgaard Helbo A, Fibiger Munch-Petersen H, Sjö L, Christensen J, Sommer Kristensen L, Asmar F, Hermansen NEU, O'Connel C, Gimsing P, Liang G, Grønbaek K.

Mol Oncol. 2018 Feb;12(2):180-195. doi: 10.1002/1878-0261.12157. Epub 2017 Dec 30.


Infective endocarditis in patients with congenital heart disease: When, where and how.

Montanaro C, Dimopoulos K, Shore DF.

Int J Cardiol. 2017 Dec 15;249:171-172. doi: 10.1016/j.ijcard.2017.09.186. No abstract available.


A crown of thorns-right ventricular outflow tract obstruction caused by calcific pericardial ring.

Heng EL, Semple T, Dimopoulos K, Nicol ED, Mohiaddin RH.

Eur Heart J Cardiovasc Imaging. 2018 Jan 1;19(1):83. doi: 10.1093/ehjci/jex228. No abstract available.


Pulmonary Arterial Hypertension Complicating Congenital Heart Disease: Advances in Therapy.

Nashat H, Brida M, Price LS, McCabe C, Alonso-Gonzalez R, Wort SJ, Kempny A, Dimopoulos K, Gatzoulis MJ.

Semin Respir Crit Care Med. 2017 Oct;38(5):636-650. doi: 10.1055/s-0037-1606222. Epub 2017 Oct 15. Review. No abstract available.


New York Heart Association (NYHA) classification in adults with congenital heart disease: relation to objective measures of exercise and outcome.

Bredy C, Ministeri M, Kempny A, Alonso-Gonzalez R, Swan L, Uebing A, Diller GP, Gatzoulis MA, Dimopoulos K.

Eur Heart J Qual Care Clin Outcomes. 2018 Jan 1;4(1):51-58. doi: 10.1093/ehjqcco/qcx031.


The CRASH report: emergency management dilemmas facing acute physicians in patients with pulmonary arterial hypertension.

Price LC, Dimopoulos K, Marino P, Alonso-Gonzalez R, McCabe C, Kemnpy A, Swan L, Boutsikou M, Al Zahrani A, Coghlan GJ, Schreiber BE, Howard LS, Davies R, Toshner M, Pepke-Zaba J, Church AC, Peacock A, Corris PA, Lordan JL, Gaine S, Condliffe R, Kiely DG, Wort SJ.

Thorax. 2017 Nov;72(11):1035-1045. doi: 10.1136/thoraxjnl-2016-209725. Epub 2017 Sep 12. Review.


Response by Kempny et al to Letter Regarding Article, "Predictors of Death in Contemporary Adult Patients With Eisenmenger Syndrome: A Multicenter Study".

Kempny A, Sørensen Hjortshøj C, Li W, Schophuus Jensen A, Søndergaard L, Diller GP, Dimopoulos K, Wort SJ, Gatzoulis MA.

Circulation. 2017 Sep 12;136(11):1078-1079. doi: 10.1161/CIRCULATIONAHA.117.029768. No abstract available.


Infective endocarditis in adults with congenital heart disease remains a lethal disease.

Tutarel O, Alonso-Gonzalez R, Montanaro C, Schiff R, Uribarri A, Kempny A, Grübler MR, Uebing A, Swan L, Diller GP, Dimopoulos K, Gatzoulis MA.

Heart. 2018 Jan;104(2):161-165. doi: 10.1136/heartjnl-2017-311650. Epub 2017 Jul 28.


Platelet count and mean platelet volume predict outcome in adults with Eisenmenger syndrome.

Martin-Garcia AC, Arachchillage DR, Kempny A, Alonso-Gonzalez R, Martin-Garcia A, Uebing A, Swan L, Wort SJ, Price LC, McCabe C, Sanchez PL, Dimopoulos K, Gatzoulis MA.

Heart. 2018 Jan;104(1):45-50. doi: 10.1136/heartjnl-2016-311144. Epub 2017 Jun 29.


Outcome of cardiac surgery in patients with congenital heart disease in England between 1997 and 2015.

Kempny A, Dimopoulos K, Uebing A, Diller GP, Rosendahl U, Belitsis G, Gatzoulis MA, Wort SJ.

PLoS One. 2017 Jun 19;12(6):e0178963. doi: 10.1371/journal.pone.0178963. eCollection 2017.


Declining incidence and prevalence of Eisenmenger syndrome in the developed world: a triumph of modern medicine.

Kempny A, Dimopoulos K, Gatzoulis MA.

Heart. 2017 Sep;103(17):1313-1314. doi: 10.1136/heartjnl-2017-311396. Epub 2017 May 31. No abstract available.


Past and current cause-specific mortality in Eisenmenger syndrome.

Hjortshøj CMS, Kempny A, Jensen AS, Sørensen K, Nagy E, Dellborg M, Johansson B, Rudiene V, Hong G, Opotowsky AR, Budts W, Mulder BJ, Tomkiewicz-Pajak L, D'Alto M, Prokšelj K, Diller GP, Dimopoulos K, Estensen ME, Holmstrøm H, Turanlahti M, Thilén U, Gatzoulis MA, Søndergaard L.

Eur Heart J. 2017 Jul 7;38(26):2060-2067. doi: 10.1093/eurheartj/ehx201.


Pacing in congenital heart disease - A four-decade experience in a single tertiary centre.

Midha D, Chen Z, Jones DG, Williams HJ, Lascelles K, Jarman J, Clague J, Till J, Dimopoulos K, Babu-Narayan SV, Markides V, Gatzoulis MA, Wong T.

Int J Cardiol. 2017 Aug 15;241:177-181. doi: 10.1016/j.ijcard.2017.02.151. Epub 2017 Mar 6.


Body mass index in adult congenital heart disease.

Brida M, Dimopoulos K, Kempny A, Liodakis E, Alonso-Gonzalez R, Swan L, Uebing A, Baumgartner H, Gatzoulis MA, Diller GP.

Heart. 2017 Aug;103(16):1250-1257. doi: 10.1136/heartjnl-2016-310571. Epub 2017 Feb 25.


Survival in portopulmonary hypertension: Outcomes of the United Kingdom National Pulmonary Arterial Hypertension Registry.

Sithamparanathan S, Nair A, Thirugnanasothy L, Coghlan JG, Condliffe R, Dimopoulos K, Elliot CA, Fisher AJ, Gaine S, Gibbs JSR, Gatzoulis MA, E Handler C, Howard LS, Johnson M, Kiely DG, Lordan JL, Peacock AJ, Pepke-Zaba J, Schreiber BE, Sheares KKK, Wort SJ, Corris PA; National Pulmonary Hypertension Service Research Collaboration of the United Kingdom and Ireland.

J Heart Lung Transplant. 2017 Jul;36(7):770-779. doi: 10.1016/j.healun.2016.12.014. Epub 2016 Dec 31.


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