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Items: 1 to 50 of 431

1.

Long non-coding RNA H19 regulates endothelial cell aging via inhibition of Stat3 signaling.

Hofmann P, Sommer J, Theodorou K, Kirchhof L, Fischer A, Li Y, Perisic L, Hedin U, Maegdefessel L, Dimmeler S, Boon RA.

Cardiovasc Res. 2018 Aug 13. doi: 10.1093/cvr/cvy206. [Epub ahead of print]

PMID:
30107531
2.

RNA Therapeutics in Cardiovascular Disease.

Lucas T, Bonauer A, Dimmeler S.

Circ Res. 2018 Jul 6;123(2):205-220. doi: 10.1161/CIRCRESAHA.117.311311.

PMID:
29976688
3.

Myeloid Kdm6b deficiency results in advanced atherosclerosis.

Neele AE, Gijbels MJJ, van der Velden S, Hoeksema MA, Boshuizen MCS, Prange KHM, Chen HJ, Van den Bossche J, van Roomen CPPA, Shami A, Levels JHM, Kroon J, Lucas T, Dimmeler S, Lutgens E, de Winther MPJ.

Atherosclerosis. 2018 Jun 1;275:156-165. doi: 10.1016/j.atherosclerosis.2018.05.052. [Epub ahead of print]

4.

Non-coding RNAs in vascular disease - from basic science to clinical applications: scientific update from the Working Group of Myocardial Function of the European Society of Cardiology.

Fiedler J, Baker AH, Dimmeler S, Heymans S, Mayr M, Thum T.

Cardiovasc Res. 2018 Aug 1;114(10):1281-1286. doi: 10.1093/cvr/cvy121.

PMID:
29800267
5.

Amyloid-β (1-40) and Mortality in Patients With Non-ST-Segment Elevation Acute Coronary Syndrome: A Cohort Study.

Stamatelopoulos K, Mueller-Hennessen M, Georgiopoulos G, Sachse M, Boeddinghaus J, Sopova K, Gatsiou A, Amrhein C, Biener M, Vafaie M, Athanasouli F, Stakos D, Pateras K, Twerenbold R, Badertscher P, Nestelberger T, Dimmeler S, Katus HA, Zeiher AM, Mueller C, Giannitsis E, Stellos K.

Ann Intern Med. 2018 Jun 19;168(12):855-865. doi: 10.7326/M17-1540. Epub 2018 May 22.

PMID:
29799975
6.

Adjusted Troponin I for Improved Evaluation of Patients with Chest Pain.

Boeckel JN, Palapies L, Klotsche J, Zeller T, von Jeinsen B, Perret MF, Kleinhaus SL, Pieper L, Tzikas S, Leistner D, Bickel C, Stalla GK, Lehnert H, Lindahl B, Wittchen HU, Silber S, Baldus S, Maerz W, Dimmeler S, Blankenberg S, Münzel T, Zeiher AM, Keller T.

Sci Rep. 2018 May 24;8(1):8087. doi: 10.1038/s41598-018-26120-1.

7.

Mechanisms of Cardiac Repair and Regeneration.

Broughton KM, Wang BJ, Firouzi F, Khalafalla F, Dimmeler S, Fernandez-Aviles F, Sussman MA.

Circ Res. 2018 Apr 13;122(8):1151-1163. doi: 10.1161/CIRCRESAHA.117.312586. Review.

PMID:
29650632
8.

A novel long non-coding RNA Myolinc regulates myogenesis through TDP-43 and Filip1.

Militello G, Hosen MR, Ponomareva Y, Gellert P, Weirick T, John D, Hindi SM, Mamchaoui K, Mouly V, Döring C, Zhang L, Nakamura M, Kumar A, Fukada SI, Dimmeler S, Uchida S.

J Mol Cell Biol. 2018 Apr 1;10(2):102-117. doi: 10.1093/jmcb/mjy025.

PMID:
29618024
9.

Switch in Laminin β2 to Laminin β1 Isoforms During Aging Controls Endothelial Cell Functions-Brief Report.

Wagner JUG, Chavakis E, Rogg EM, Muhly-Reinholz M, Glaser SF, Günther S, John D, Bonini F, Zeiher AM, Schaefer L, Hannocks MJ, Boon RA, Dimmeler S.

Arterioscler Thromb Vasc Biol. 2018 May;38(5):1170-1177. doi: 10.1161/ATVBAHA.117.310685. Epub 2018 Mar 29.

PMID:
29599141
10.

Airn Regulates Igf2bp2 Translation in Cardiomyocytes.

Hosen MR, Militello G, Weirick T, Ponomareva Y, Dassanayaka S, Moore JB 4th, Döring C, Wysoczynski M, Jones SP, Dimmeler S, Uchida S.

Circ Res. 2018 May 11;122(10):1347-1353. doi: 10.1161/CIRCRESAHA.117.312215. Epub 2018 Feb 26.

PMID:
29483092
11.

Clonal Expansion of Endothelial Cells Contributes to Ischemia-Induced Neovascularization.

Manavski Y, Lucas T, Glaser SF, Dorsheimer L, Günther S, Braun T, Rieger MA, Zeiher AM, Boon RA, Dimmeler S.

Circ Res. 2018 Mar 2;122(5):670-677. doi: 10.1161/CIRCRESAHA.117.312310. Epub 2018 Jan 22.

PMID:
29358229
12.

The lncRNA GATA6-AS epigenetically regulates endothelial gene expression via interaction with LOXL2.

Neumann P, Jaé N, Knau A, Glaser SF, Fouani Y, Rossbach O, Krüger M, John D, Bindereif A, Grote P, Boon RA, Dimmeler S.

Nat Commun. 2018 Jan 16;9(1):237. doi: 10.1038/s41467-017-02431-1.

13.

Comparison of MOLLI, shMOLLLI, and SASHA in discrimination between health and disease and relationship with histologically derived collagen volume fraction.

Child N, Suna G, Dabir D, Yap ML, Rogers T, Kathirgamanathan M, Arroyo-Ucar E, Hinojar R, Mahmoud I, Young C, Wendler O, Mayr M, Sandhu B, Morton G, Muhly-Reinholz M, Dimmeler S, Nagel E, Puntmann VO.

Eur Heart J Cardiovasc Imaging. 2018 Jul 1;19(7):768-776. doi: 10.1093/ehjci/jex309.

PMID:
29237044
14.

Genetic and pharmacological inhibition of microRNA-92a maintains podocyte cell cycle quiescence and limits crescentic glomerulonephritis.

Henique C, Bollée G, Loyer X, Grahammer F, Dhaun N, Camus M, Vernerey J, Guyonnet L, Gaillard F, Lazareth H, Meyer C, Bensaada I, Legrès L, Satoh T, Akira S, Bruneval P, Dimmeler S, Tedgui A, Karras A, Thervet E, Nochy D, Huber TB, Mesnard L, Lenoir O, Tharaux PL.

Nat Commun. 2017 Nov 28;8(1):1829. doi: 10.1038/s41467-017-01885-7.

15.

The effect of intracoronary infusion of bone marrow-derived mononuclear cells on all-cause mortality in acute myocardial infarction: rationale and design of the BAMI trial.

Mathur A, Arnold R, Assmus B, Bartunek J, Belmans A, Bönig H, Crea F, Dimmeler S, Dowlut S, Fernández-Avilés F, Galiñanes M, Garcia-Dorado D, Hartikainen J, Hill J, Hogardt-Noll A, Homsy C, Janssens S, Kala P, Kastrup J, Martin J, Menasche P, Miklik R, Mozid A, San Román JA, Sanz-Ruiz R, Tendera M, Wojakowski W, Ylä-Herttuala S, Zeiher A.

Eur J Heart Fail. 2017 Nov;19(11):1545-1550. doi: 10.1002/ejhf.829. Epub 2017 Sep 25.

PMID:
28948706
16.

Heparin Induces the Mobilization of Heart-Derived Multipotent Mesoangioblasts During Cardiac Surgery With Cardiopulmonary Bypass or Cardiac Catheterization.

Hata Y, Iwasaki M, Fujitaka K, Park H, Sato D, Enoki C, Minato N, Horitani K, Nakano M, Kishimoto H, Wada K, Koyanagi M, Adachi Y, Yamamoto Y, Zeiher AM, Dimmeler S, Shiojima I.

Circ J. 2018 Apr 25;82(5):1459-1465. doi: 10.1253/circj.CJ-17-0324. Epub 2017 Sep 21.

17.

Cardiovascular Research in Germany.

Heusch G, Eschenhagen T, Dimmeler S.

Circ Res. 2017 Aug 18;121(5):492-495. doi: 10.1161/CIRCRESAHA.117.311132. No abstract available.

PMID:
28819038
18.

Improved risk stratification in prevention by use of a panel of selected circulating microRNAs.

Keller T, Boeckel JN, Groß S, Klotsche J, Palapies L, Leistner D, Pieper L, Stalla GK, Lehnert H, Silber S, Pittrow D, Maerz W, Dörr M, Wittchen HU, Baumeister SE, Völker U, Felix SB, Dimmeler S, Zeiher AM.

Sci Rep. 2017 Jul 3;7(1):4511. doi: 10.1038/s41598-017-04040-w.

19.

Identification and Functional Characterization of Hypoxia-Induced Endoplasmic Reticulum Stress Regulating lncRNA (HypERlnc) in Pericytes.

Bischoff FC, Werner A, John D, Boeckel JN, Melissari MT, Grote P, Glaser SF, Demolli S, Uchida S, Michalik KM, Meder B, Katus HA, Haas J, Chen W, Pullamsetti SS, Seeger W, Zeiher AM, Dimmeler S, Zehendner CM.

Circ Res. 2017 Aug 4;121(4):368-375. doi: 10.1161/CIRCRESAHA.116.310531. Epub 2017 Jun 13.

PMID:
28611075
20.

Transcoronary Concentration Gradient of microRNA-133a and Outcome in Patients With Coronary Artery Disease.

De Rosa R, De Rosa S, Leistner D, Boeckel JN, Keller T, Fichtlscherer S, Dimmeler S, Zeiher AM.

Am J Cardiol. 2017 Jul 1;120(1):15-24. doi: 10.1016/j.amjcard.2017.03.264. Epub 2017 Apr 12.

PMID:
28511772
21.

Light-inducible antimiR-92a as a therapeutic strategy to promote skin repair in healing-impaired diabetic mice.

Lucas T, Schäfer F, Müller P, Eming SA, Heckel A, Dimmeler S.

Nat Commun. 2017 May 2;8:15162. doi: 10.1038/ncomms15162.

22.

Epigenomic and transcriptomic approaches in the post-genomic era: path to novel targets for diagnosis and therapy of the ischaemic heart? Position Paper of the European Society of Cardiology Working Group on Cellular Biology of the Heart.

Perrino C, Barabási AL, Condorelli G, Davidson SM, De Windt L, Dimmeler S, Engel FB, Hausenloy DJ, Hill JA, Van Laake LW, Lecour S, Leor J, Madonna R, Mayr M, Prunier F, Sluijter JPG, Schulz R, Thum T, Ytrehus K, Ferdinandy P.

Cardiovasc Res. 2017 Jun 1;113(7):725-736. doi: 10.1093/cvr/cvx070. Review.

23.

Shear stress-regulated miR-27b controls pericyte recruitment by repressing SEMA6A and SEMA6D.

Demolli S, Doddaballapur A, Devraj K, Stark K, Manavski Y, Eckart A, Zehendner CM, Lucas T, Korff T, Hecker M, Massberg S, Liebner S, Kaluza D, Boon RA, Dimmeler S.

Cardiovasc Res. 2017 May 1;113(6):681-691. doi: 10.1093/cvr/cvx032.

PMID:
28453731
24.

Endogenous developmental endothelial locus-1 limits ischaemia-related angiogenesis by blocking inflammation.

Klotzsche-von Ameln A, Cremer S, Hoffmann J, Schuster P, Khedr S, Korovina I, Troullinaki M, Neuwirth A, Sprott D, Chatzigeorgiou A, Economopoulou M, Orlandi A, Hain A, Zeiher AM, Deussen A, Hajishengallis G, Dimmeler S, Chavakis T, Chavakis E.

Thromb Haemost. 2017 Jun 2;117(6):1150-1163. doi: 10.1160/TH16-05-0354. Epub 2017 Apr 27.

25.

Non-coding RNAs in cardiovascular diseases: diagnostic and therapeutic perspectives.

Poller W, Dimmeler S, Heymans S, Zeller T, Haas J, Karakas M, Leistner DM, Jakob P, Nakagawa S, Blankenberg S, Engelhardt S, Thum T, Weber C, Meder B, Hajjar R, Landmesser U.

Eur Heart J. 2017 Apr 18. doi: 10.1093/eurheartj/ehx165. [Epub ahead of print]

PMID:
28430919
26.

Netting Insights into Fibrosis.

Dimmeler S, Zeiher AM.

N Engl J Med. 2017 Apr 13;376(15):1475-1477. doi: 10.1056/NEJMcibr1616598. No abstract available.

PMID:
28402777
27.

Long Noncoding RNA MANTIS Facilitates Endothelial Angiogenic Function.

Leisegang MS, Fork C, Josipovic I, Richter FM, Preussner J, Hu J, Miller MJ, Epah J, Hofmann P, Günther S, Moll F, Valasarajan C, Heidler J, Ponomareva Y, Freiman TM, Maegdefessel L, Plate KH, Mittelbronn M, Uchida S, Künne C, Stellos K, Schermuly RT, Weissmann N, Devraj K, Wittig I, Boon RA, Dimmeler S, Pullamsetti SS, Looso M, Miller FJ Jr, Brandes RP.

Circulation. 2017 Jul 4;136(1):65-79. doi: 10.1161/CIRCULATIONAHA.116.026991. Epub 2017 Mar 28.

28.

Endothelial transcription factor KLF2 negatively regulates liver regeneration via induction of activin A.

Manavski Y, Abel T, Hu J, Kleinlützum D, Buchholz CJ, Belz C, Augustin HG, Boon RA, Dimmeler S.

Proc Natl Acad Sci U S A. 2017 Apr 11;114(15):3993-3998. doi: 10.1073/pnas.1613392114. Epub 2017 Mar 27.

29.

Circular RNAs in heart failure.

Devaux Y, Creemers EE, Boon RA, Werfel S, Thum T, Engelhardt S, Dimmeler S, Squire I; Cardiolinc network.

Eur J Heart Fail. 2017 Jun;19(6):701-709. doi: 10.1002/ejhf.801. Epub 2017 Mar 27. Review.

30.

Macrophage Kdm6b controls the pro-fibrotic transcriptome signature of foam cells.

Neele AE, Prange KH, Hoeksema MA, van der Velden S, Lucas T, Dimmeler S, Lutgens E, Van den Bossche J, de Winther MP.

Epigenomics. 2017 Apr;9(4):383-391. doi: 10.2217/epi-2016-0152. Epub 2017 Mar 21.

PMID:
28322580
31.

The consensus of the Task Force of the European Society of Cardiology concerning the clinical investigation of the use of autologous adult stem cells for the treatment of acute myocardial infarction and heart failure: update 2016.

Mathur A, Fernández-Avilés F, Dimmeler S, Hauskeller C, Janssens S, Menasche P, Wojakowski W, Martin JF, Zeiher A; BAMI Investigators.

Eur Heart J. 2017 Oct 14;38(39):2930-2935. doi: 10.1093/eurheartj/ehw640. No abstract available.

32.

Logic programming to infer complex RNA expression patterns from RNA-seq data.

Weirick T, Militello G, Ponomareva Y, John D, Döring C, Dimmeler S, Uchida S.

Brief Bioinform. 2018 Mar 1;19(2):199-209. doi: 10.1093/bib/bbw117.

PMID:
28011754
33.

Long Noncoding RNA Meg3 Controls Endothelial Cell Aging and Function: Implications for Regenerative Angiogenesis.

Boon RA, Hofmann P, Michalik KM, Lozano-Vidal N, Berghäuser D, Fischer A, Knau A, Jaé N, Schürmann C, Dimmeler S.

J Am Coll Cardiol. 2016 Dec 13;68(23):2589-2591. doi: 10.1016/j.jacc.2016.09.949. No abstract available.

34.

Titin Forms Circles: Regulation by Heart Failure and the RNA-Binding Protein RBM20.

Jaé N, Dimmeler S.

Circ Res. 2016 Oct 14;119(9):966-968. No abstract available.

PMID:
27737936
35.

RNAEditor: easy detection of RNA editing events and the introduction of editing islands.

John D, Weirick T, Dimmeler S, Uchida S.

Brief Bioinform. 2017 Nov 1;18(6):993-1001. doi: 10.1093/bib/bbw087.

PMID:
27694136
36.

RNA Therapeutics for Treatment of Cardiovascular Diseases: Promises and Challenges.

Lucas T, Dimmeler S.

Circ Res. 2016 Sep 16;119(7):794-7. doi: 10.1161/CIRCRESAHA.116.308730. Review. No abstract available.

PMID:
27635083
37.

Adenosine-to-inosine RNA editing controls cathepsin S expression in atherosclerosis by enabling HuR-mediated post-transcriptional regulation.

Stellos K, Gatsiou A, Stamatelopoulos K, Perisic Matic L, John D, Lunella FF, Jaé N, Rossbach O, Amrhein C, Sigala F, Boon RA, Fürtig B, Manavski Y, You X, Uchida S, Keller T, Boeckel JN, Franco-Cereceda A, Maegdefessel L, Chen W, Schwalbe H, Bindereif A, Eriksson P, Hedin U, Zeiher AM, Dimmeler S.

Nat Med. 2016 Oct;22(10):1140-1150. doi: 10.1038/nm.4172. Epub 2016 Sep 5.

PMID:
27595325
38.

ANGIOGENES: knowledge database for protein-coding and noncoding RNA genes in endothelial cells.

Müller R, Weirick T, John D, Militello G, Chen W, Dimmeler S, Uchida S.

Sci Rep. 2016 Sep 1;6:32475. doi: 10.1038/srep32475.

39.

Screening and validation of lncRNAs and circRNAs as miRNA sponges.

Militello G, Weirick T, John D, Döring C, Dimmeler S, Uchida S.

Brief Bioinform. 2017 Sep 1;18(5):780-788. doi: 10.1093/bib/bbw053.

PMID:
27373735
40.

Novel therapeutic strategies targeting fibroblasts and fibrosis in heart disease.

Gourdie RG, Dimmeler S, Kohl P.

Nat Rev Drug Discov. 2016 Sep;15(9):620-38. doi: 10.1038/nrd.2016.89. Epub 2016 Jun 24. Review.

41.

JMJD8 Regulates Angiogenic Sprouting and Cellular Metabolism by Interacting With Pyruvate Kinase M2 in Endothelial Cells.

Boeckel JN, Derlet A, Glaser SF, Luczak A, Lucas T, Heumüller AW, Krüger M, Zehendner CM, Kaluza D, Doddaballapur A, Ohtani K, Treguer K, Dimmeler S.

Arterioscler Thromb Vasc Biol. 2016 Jul;36(7):1425-33. doi: 10.1161/ATVBAHA.116.307695. Epub 2016 May 19.

PMID:
27199445
42.

Metabolism Regulates Cellular Functions of Bone Marrow-Derived Cells used for Cardiac Therapy.

Derlet A, Rasper T, Roy Choudhury A, Bothur S, Rieger MA, Namgaladze D, Fischer A, Schürmann C, Brandes RP, Tschulena U, Steppan S, Assmus B, Dimmeler S, Zeiher AM, Seeger FH.

Stem Cells. 2016 Aug;34(8):2236-48. doi: 10.1002/stem.2394. Epub 2016 May 25.

43.

Inhibition of let-7 augments the recruitment of epicardial cells and improves cardiac function after myocardial infarction.

Seeger T, Xu QF, Muhly-Reinholz M, Fischer A, Kremp EM, Zeiher AM, Dimmeler S.

J Mol Cell Cardiol. 2016 May;94:145-152. doi: 10.1016/j.yjmcc.2016.04.002. Epub 2016 Apr 9.

PMID:
27071338
44.

Long Noncoding RNAs: From Clinical Genetics to Therapeutic Targets?

Boon RA, Jaé N, Holdt L, Dimmeler S.

J Am Coll Cardiol. 2016 Mar 15;67(10):1214-1226. doi: 10.1016/j.jacc.2015.12.051. Review.

45.

Transcoronary gradients of vascular miRNAs and coronary atherosclerotic plaque characteristics.

Leistner DM, Boeckel JN, Reis SM, Thome CE, De Rosa R, Keller T, Palapies L, Fichtlscherer S, Dimmeler S, Zeiher AM.

Eur Heart J. 2016 Jun 7;37(22):1738-49. doi: 10.1093/eurheartj/ehw047. Epub 2016 Feb 24.

PMID:
26916800
46.

Long noncoding RNA MALAT1-derived mascRNA is involved in cardiovascular innate immunity.

Gast M, Schroen B, Voigt A, Haas J, Kuehl U, Lassner D, Skurk C, Escher F, Wang X, Kratzer A, Michalik K, Papageorgiou A, Peters T, Loebel M, Wilk S, Althof N, Prasanth KV, Katus H, Meder B, Nakagawa S, Scheibenbogen C, Schultheiss HP, Landmesser U, Dimmeler S, Heymans S, Poller W.

J Mol Cell Biol. 2016 Apr;8(2):178-81. doi: 10.1093/jmcb/mjw003. Epub 2016 Jan 27. No abstract available.

PMID:
26823496
47.

Improved outcome with repeated intracoronary injection of bone marrow-derived cells within a registry: rationale for the randomized outcome trial REPEAT.

Assmus B, Alakmeh S, De Rosa S, Bönig H, Hermann E, Levy WC, Dimmeler S, Zeiher AM.

Eur Heart J. 2016 Jun 1;37(21):1659-66. doi: 10.1093/eurheartj/ehv559. Epub 2015 Oct 29.

48.

MicroRNA-30 mediates anti-inflammatory effects of shear stress and KLF2 via repression of angiopoietin 2.

Demolli S, Doebele C, Doddaballapur A, Lang V, Fisslthaler B, Chavakis E, Vinciguerra M, Sciacca S, Henschler R, Hecker M, Savant S, Augustin HG, Kaluza D, Dimmeler S, Boon RA.

J Mol Cell Cardiol. 2015 Nov;88:111-9. doi: 10.1016/j.yjmcc.2015.10.009. Epub 2015 Oct 9.

PMID:
26456066
49.

Perfectly placed: Stefanie Dimmeler on theimportance of finding the right niche.

Dimmeler S, Ozkan J.

Eur Heart J. 2015 Oct 7;36(38):2548-9. doi: 10.1093/eurheartj/ehv389. No abstract available.

PMID:
26446241
50.

Identification and Characterization of Hypoxia-Regulated Endothelial Circular RNA.

Boeckel JN, Jaé N, Heumüller AW, Chen W, Boon RA, Stellos K, Zeiher AM, John D, Uchida S, Dimmeler S.

Circ Res. 2015 Oct 23;117(10):884-90. doi: 10.1161/CIRCRESAHA.115.306319. Epub 2015 Sep 16.

PMID:
26377962

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