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Items: 1 to 50 of 87

1.

Sequence features of variable region determining physicochemical properties and polyreactivity of therapeutic antibodies.

Lecerf M, Kanyavuz A, Lacroix-Desmazes S, Dimitrov JD.

Mol Immunol. 2019 Aug;112:338-346. doi: 10.1016/j.molimm.2019.06.012. Epub 2019 Jun 26.

PMID:
31254774
2.

Natural Antibodies: from First-Line Defense Against Pathogens to Perpetual Immune Homeostasis.

Maddur MS, Lacroix-Desmazes S, Dimitrov JD, Kazatchkine MD, Bayry J, Kaveri SV.

Clin Rev Allergy Immunol. 2019 Jun 3. doi: 10.1007/s12016-019-08746-9. [Epub ahead of print] Review.

PMID:
31161341
3.

Use of cysteine as a spectroscopic probe for determination of heme-scavenging capacity of serum proteins and whole human serum.

Noé R, Bozinovic N, Lecerf M, Lacroix-Desmazes S, Dimitrov JD.

J Pharm Biomed Anal. 2019 Aug 5;172:311-319. doi: 10.1016/j.jpba.2019.05.013. Epub 2019 May 7.

4.

Anti-inflammatory activity of intravenous immunoglobulin through scavenging of heme.

Wiatr M, Merle NS, Boudhabhay I, Poillerat V, Rossini S, Lecerf M, Kaveri SV, Lacroix-Desmazes S, Roumenina LT, Dimitrov JD.

Mol Immunol. 2019 Jul;111:205-208. doi: 10.1016/j.molimm.2019.04.020. Epub 2019 May 10.

5.

HIV-1 Envelope Recognition by Polyreactive and Cross-Reactive Intestinal B Cells.

Planchais C, Kök A, Kanyavuz A, Lorin V, Bruel T, Guivel-Benhassine F, Rollenske T, Prigent J, Hieu T, Prazuck T, Lefrou L, Wardemann H, Schwartz O, Dimitrov JD, Hocqueloux L, Mouquet H.

Cell Rep. 2019 Apr 9;27(2):572-585.e7. doi: 10.1016/j.celrep.2019.03.032.

6.

P-selectin drives complement attack on endothelium during intravascular hemolysis in TLR-4/heme-dependent manner.

Merle NS, Paule R, Leon J, Daugan M, Robe-Rybkine T, Poillerat V, Torset C, Frémeaux-Bacchi V, Dimitrov JD, Roumenina LT.

Proc Natl Acad Sci U S A. 2019 Mar 26;116(13):6280-6285. doi: 10.1073/pnas.1814797116. Epub 2019 Mar 8.

PMID:
30850533
7.

Breaking the law: unconventional strategies for antibody diversification.

Kanyavuz A, Marey-Jarossay A, Lacroix-Desmazes S, Dimitrov JD.

Nat Rev Immunol. 2019 Jun;19(6):355-368. doi: 10.1038/s41577-019-0126-7. Review.

PMID:
30718829
8.

Heme Drives Susceptibility of Glomerular Endothelium to Complement Overactivation Due to Inefficient Upregulation of Heme Oxygenase-1.

May O, Merle NS, Grunenwald A, Gnemmi V, Leon J, Payet C, Robe-Rybkine T, Paule R, Delguste F, Satchell SC, Mathieson PW, Hazzan M, Boulanger E, Dimitrov JD, Fremeaux-Bacchi V, Frimat M, Roumenina LT.

Front Immunol. 2018 Dec 20;9:3008. doi: 10.3389/fimmu.2018.03008. eCollection 2018.

9.

Intravenous immunoglobulin induces IL-4 in human basophils by signaling through surface-bound IgE.

Galeotti C, Stephen-Victor E, Karnam A, Das M, Gilardin L, Maddur MS, Wymann S, Vonarburg C, Chevailler A, Dimitrov JD, Benveniste O, Bruhns P, Kaveri SV, Bayry J.

J Allergy Clin Immunol. 2019 Aug;144(2):524-535.e8. doi: 10.1016/j.jaci.2018.10.064. Epub 2018 Dec 7.

PMID:
30529242
10.

Intravascular hemolysis activates complement via cell-free heme and heme-loaded microvesicles.

Merle NS, Grunenwald A, Rajaratnam H, Gnemmi V, Frimat M, Figueres ML, Knockaert S, Bouzekri S, Charue D, Noe R, Robe-Rybkine T, Le-Hoang M, Brinkman N, Gentinetta T, Edler M, Petrillo S, Tolosano E, Miescher S, Le Jeune S, Houillier P, Chauvet S, Rabant M, Dimitrov JD, Fremeaux-Bacchi V, Blanc-Brude OP, Roumenina LT.

JCI Insight. 2018 Jun 21;3(12). pii: 96910. doi: 10.1172/jci.insight.96910. eCollection 2018 Jun 21.

11.

Conformational Plasticity in Broadly Neutralizing HIV-1 Antibodies Triggers Polyreactivity.

Prigent J, Jarossay A, Planchais C, Eden C, Dufloo J, Kök A, Lorin V, Vratskikh O, Couderc T, Bruel T, Schwartz O, Seaman MS, Ohlenschläger O, Dimitrov JD, Mouquet H.

Cell Rep. 2018 May 29;23(9):2568-2581. doi: 10.1016/j.celrep.2018.04.101.

12.

Characterization of Renal Injury and Inflammation in an Experimental Model of Intravascular Hemolysis.

Merle NS, Grunenwald A, Figueres ML, Chauvet S, Daugan M, Knockaert S, Robe-Rybkine T, Noe R, May O, Frimat M, Brinkman N, Gentinetta T, Miescher S, Houillier P, Legros V, Gonnet F, Blanc-Brude OP, Rabant M, Daniel R, Dimitrov JD, Roumenina LT.

Front Immunol. 2018 Mar 1;9:179. doi: 10.3389/fimmu.2018.00179. eCollection 2018.

13.

Oxidation of factor VIII increases its immunogenicity in mice with severe hemophilia A.

Peyron I, Dimitrov JD, Delignat S, Gangadharan B, Srivastava A, Kaveri SV, Lacroix-Desmazes S.

Cell Immunol. 2018 Mar;325:64-68. doi: 10.1016/j.cellimm.2018.01.008. Epub 2018 Jan 31.

PMID:
29395036
14.

Potential Predictive Role of Lipid Peroxidation Markers for Type 2 Diabetes in the Adult Tunisian Population.

Bouhajja H, Kacem FH, Abdelhedi R, Ncir M, Dimitrov JD, Marrakchi R, Jamoussi K, Rebai A, El Feki A, Abid M, Ayadi H, Kaveri SV, Mnif-Feki M, Bougacha-Elleuch N.

Can J Diabetes. 2018 Jun;42(3):263-271. doi: 10.1016/j.jcjd.2017.06.006. Epub 2017 Jul 19.

PMID:
28734952
15.

Methods for Posttranslational Induction of Polyreactivity of Antibodies.

Lecerf M, Jarossay A, Kaveri SV, Lacroix-Desmazes S, Dimitrov JD.

Methods Mol Biol. 2017;1643:135-145. doi: 10.1007/978-1-4939-7180-0_10.

PMID:
28667534
16.

Impact of Antigen Density on the Binding Mechanism of IgG Antibodies.

Hadzhieva M, Pashov AD, Kaveri S, Lacroix-Desmazes S, Mouquet H, Dimitrov JD.

Sci Rep. 2017 Jun 19;7(1):3767. doi: 10.1038/s41598-017-03942-z.

17.

Heme-Exposed Pooled Therapeutic IgG Improves Endotoxemia Survival.

Djoumerska-Alexieva I, Roumenina LT, Stefanova T, Vassilev T, Dimitrov JD.

Inflammation. 2017 Feb;40(1):117-122. doi: 10.1007/s10753-016-0460-x.

PMID:
27796617
18.

Relationship between natural and heme-mediated antibody polyreactivity.

Hadzhieva M, Vassilev T, Bayry J, Kaveri S, Lacroix-Desmazes S, Dimitrov JD.

Biochem Biophys Res Commun. 2016 Mar 25;472(1):281-6. doi: 10.1016/j.bbrc.2016.02.112. Epub 2016 Feb 27.

PMID:
26926563
19.

Heme: Modulator of Plasma Systems in Hemolytic Diseases.

Roumenina LT, Rayes J, Lacroix-Desmazes S, Dimitrov JD.

Trends Mol Med. 2016 Mar;22(3):200-213. doi: 10.1016/j.molmed.2016.01.004. Epub 2016 Feb 12. Review.

PMID:
26875449
20.

[Protocol to induce abortion using Mifepristone and Misoprostol].

Andreeva A, Dimitrov J, Marinov B.

Akush Ginekol (Sofiia). 2015;54(9):62-7. Bulgarian. No abstract available.

PMID:
26863800
21.

Heme oxygenase-1 is dispensable for the anti-inflammatory activity of intravenous immunoglobulin.

Galeotti C, Hegde P, Das M, Stephen-Victor E, Canale F, Muñoz M, Sharma VK, Dimitrov JD, Kaveri SV, Bayry J.

Sci Rep. 2016 Jan 22;6:19592. doi: 10.1038/srep19592.

22.

Intravenous Immunoglobulin with Enhanced Polyspecificity Improves Survival in Experimental Sepsis and Aseptic Systemic Inflammatory Response Syndromes.

Djoumerska-Alexieva I, Roumenina L, Pashov A, Dimitrov J, Hadzhieva M, Lindig S, Voynova E, Dimitrova P, Ivanovska N, Bockmeyer C, Stefanova Z, Fitting C, Bläss M, Claus R, von Gunten S, Kaveri S, Cavaillon JM, Bauer M, Vassilev T.

Mol Med. 2016 Apr;21(1):1002-1010. doi: 10.2119/molmed.2014.00224. Epub 2016 Mar 31.

23.

Neutralization of Japanese Encephalitis Virus by heme-induced broadly reactive human monoclonal antibody.

Gupta N, de Wispelaere M, Lecerf M, Kalia M, Scheel T, Vrati S, Berek C, Kaveri SV, Desprès P, Lacroix-Desmazes S, Dimitrov JD.

Sci Rep. 2015 Nov 6;5:16248. doi: 10.1038/srep16248.

24.

Functional Characterization of Autoantibodies against Complement Component C3 in Patients with Lupus Nephritis.

Vasilev VV, Noe R, Dragon-Durey MA, Chauvet S, Lazarov VJ, Deliyska BP, Fremeaux-Bacchi V, Dimitrov JD, Roumenina LT.

J Biol Chem. 2015 Oct 16;290(42):25343-55. doi: 10.1074/jbc.M115.647008. Epub 2015 Aug 5.

25.

Natural and Induced Antibody Polyreactivity.

Jarossay A, Hadzhieva M, Kaveri SV, Lacroix-Desmazes S, Dimitrov JD.

Anticancer Agents Med Chem. 2015;15(10):1230-41.

PMID:
26179269
26.

Materno-Fetal Transfer of Preproinsulin Through the Neonatal Fc Receptor Prevents Autoimmune Diabetes.

Culina S, Gupta N, Boisgard R, Afonso G, Gagnerault MC, Dimitrov J, Østerbye T, Justesen S, Luce S, Attias M, Kyewski B, Buus S, Wong FS, Lacroix-Desmazes S, Mallone R.

Diabetes. 2015 Oct;64(10):3532-42. doi: 10.2337/db15-0024. Epub 2015 Apr 27.

27.

Correction to Mechanism and functional implications of the heme-induced binding promiscuity of IgE.

Hadzhieva M, Vassilev TL, Roumenina LT, Bayry J, Kaveri SV, Lacroix-Desmazes S, Dimitrov JD.

Biochemistry. 2015 Apr 14;54(14):2399. doi: 10.1021/acs.biochem.5b00323. Epub 2015 Apr 3. No abstract available.

PMID:
25839915
28.

Mechanism and functional implications of the heme-induced binding promiscuity of IgE.

Hadzhieva M, Vassilev TL, Roumenina LT, Bayry J, Kaveri SV, Lacroix-Desmazes S, Dimitrov JD.

Biochemistry. 2015 Mar 24;54(11):2061-72. doi: 10.1021/bi501507m. Epub 2015 Mar 11. Erratum in: Biochemistry. 2015 Apr 14;54(14):2399.

PMID:
25742488
29.

Regulation of immune responses to protein therapeutics by transplacental induction of T cell tolerance.

Gupta N, Culina S, Meslier Y, Dimitrov J, Arnoult C, Delignat S, Gangadharan B, Lecerf M, Justesen S, Gouilleux-Gruart V, Salomon BL, Scott DW, Kaveri SV, Mallone R, Lacroix-Desmazes S.

Sci Transl Med. 2015 Feb 18;7(275):275ra21. doi: 10.1126/scitranslmed.aaa1957.

PMID:
25696000
30.

Prevalence and gene characteristics of antibodies with cofactor-induced HIV-1 specificity.

Lecerf M, Scheel T, Pashov AD, Jarossay A, Ohayon D, Planchais C, Mesnage S, Berek C, Kaveri SV, Lacroix-Desmazes S, Dimitrov JD.

J Biol Chem. 2015 Feb 20;290(8):5203-13. doi: 10.1074/jbc.M114.618124. Epub 2015 Jan 6.

31.

Haemarthrosis and arthropathy do not favour the development of factor VIII inhibitors in severe haemophilia A mice.

Peyron I, Dimitrov JD, Delignat S, Gangadharan B, Planchais C, Kaveri SV, Lacroix-Desmazes S.

Haemophilia. 2015 Jan;21(1):e94-8. doi: 10.1111/hae.12579. Epub 2014 Dec 4. No abstract available.

PMID:
25471131
32.

Molecular basis for bacterial peptidoglycan recognition by LysM domains.

Mesnage S, Dellarole M, Baxter NJ, Rouget JB, Dimitrov JD, Wang N, Fujimoto Y, Hounslow AM, Lacroix-Desmazes S, Fukase K, Foster SJ, Williamson MP.

Nat Commun. 2014 Jun 30;5:4269. doi: 10.1038/ncomms5269.

33.

A cryptic polyreactive antibody recognizes distinct clades of HIV-1 glycoprotein 120 by an identical binding mechanism.

Dimitrov JD, Planchais C, Scheel T, Ohayon D, Mesnage S, Berek C, Kaveri SV, Lacroix-Desmazes S.

J Biol Chem. 2014 Jun 20;289(25):17767-79. doi: 10.1074/jbc.M114.556266. Epub 2014 May 6.

34.

Cryptic polyreactivity of IgG expressed by splenic marginal zone B-cell lymphoma.

Mahendra A, Gangadharan B, André S, Boudjoghra M, Davi F, Lecerf M, Planchais C, Kaveri SV, Lacroix-Desmazes S, Dimitrov JD.

Mol Immunol. 2014 Jul;60(1):54-61. doi: 10.1016/j.molimm.2014.03.009. Epub 2014 Apr 24.

PMID:
24769492
35.

Thermodynamic stability contributes to immunoglobulin specificity.

Dimitrov JD, Kaveri SV, Lacroix-Desmazes S.

Trends Biochem Sci. 2014 May;39(5):221-6. doi: 10.1016/j.tibs.2014.02.010. Epub 2014 Mar 28.

PMID:
24685657
36.

Predictive immunogenicity of Refacto AF.

Delignat S, Repessé Y, Gilardin L, Dimitrov JD, Lone YC, Kaveri SV, Lacroix-Desmazes S.

Haemophilia. 2014 Jul;20(4):486-92. doi: 10.1111/hae.12348. Epub 2013 Dec 30.

PMID:
24372710
37.

[Post-translational diversification of immunoglobulins specificity].

Planchais C, Gupta N, Kaveri SV, Lacroix-Desmazes S, Dimitrov JD.

Med Sci (Paris). 2013 Nov;29(11):937-40. doi: 10.1051/medsci/20132911002. Epub 2013 Nov 20. French. No abstract available.

38.

The interaction between factor H and VWF increases factor H cofactor activity and regulates VWF prothrombotic status.

Rayes J, Roumenina LT, Dimitrov JD, Repessé Y, Ing M, Christophe O, Jokiranta TS, Halbwachs-Mecarelli L, Borel-Derlon A, Kaveri SV, Frémeaux-Bacchi V, Lacroix-Desmazes S.

Blood. 2014 Jan 2;123(1):121-5. doi: 10.1182/blood-2013-04-495853. Epub 2013 Sep 6.

39.

Serum or breast milk immunoglobulins mask the self-reactivity of human natural IgG antibodies.

Djoumerska-Alexieva I, Manoylov I, Dimitrov JD, Tchorbanov A.

APMIS. 2014 Apr;122(4):329-40. doi: 10.1111/apm.12149. Epub 2013 Aug 13.

PMID:
23937153
40.

Antibody polyreactivity in health and disease: statu variabilis.

Dimitrov JD, Planchais C, Roumenina LT, Vassilev TL, Kaveri SV, Lacroix-Desmazes S.

J Immunol. 2013 Aug 1;191(3):993-9. doi: 10.4049/jimmunol.1300880. Review.

41.

Longitudinal and integrative biomodeling of effector and memory immune compartments after inactivated influenza vaccination.

Bonduelle O, Yahia N, Siberil S, Benhabiles N, Carrat F, Krivine A, Rozenberg F, Dimitrov J, Kaveri SV, Curjol A, Tindel M, Louet M, Desert F, Launay O, Loulergue P, Badre G, Katlama C, Bricaire F, Samri A, Rousset D, van der Werf S, Jauréguiberry S, Combadiere B.

J Immunol. 2013 Jul 15;191(2):623-31. doi: 10.4049/jimmunol.1203483. Epub 2013 Jun 17.

42.

Development of inhibitory antibodies to therapeutic factor VIII in severe hemophilia A is associated with microsatellite polymorphisms in the HMOX1 promoter.

Repessé Y, Peyron I, Dimitrov JD, Dasgupta S, Moshai EF, Costa C, Borel-Derlon A, Guillet B, D'Oiron R, Aouba A, Rothschild C, Oldenburg J, Pavlova A, Kaveri SV, Lacroix-Desmazes S; ABIRISK consortium.

Haematologica. 2013 Oct;98(10):1650-5. doi: 10.3324/haematol.2013.084665. Epub 2013 May 28.

43.

Complement activation by heme as a secondary hit for atypical hemolytic uremic syndrome.

Frimat M, Tabarin F, Dimitrov JD, Poitou C, Halbwachs-Mecarelli L, Fremeaux-Bacchi V, Roumenina LT.

Blood. 2013 Jul 11;122(2):282-92. doi: 10.1182/blood-2013-03-489245. Epub 2013 May 21.

44.

Gain of function of immunoglobulins after partial unfolding or cofactor binding.

Dimitrov JD, Kaveri SV, Lacroix-Desmazes S.

Mol Immunol. 2013 Oct;55(3-4):195-6. doi: 10.1016/j.molimm.2013.03.009. Epub 2013 Apr 9.

PMID:
23582926
45.

Antibody-mediated catalysis: induction and therapeutic relevance.

Mahendra A, Sharma M, Rao DN, Peyron I, Planchais C, Dimitrov JD, Kaveri SV, Lacroix-Desmazes S.

Autoimmun Rev. 2013 Apr;12(6):648-52. doi: 10.1016/j.autrev.2012.10.009. Epub 2012 Nov 30. Review.

PMID:
23207286
46.

Antibody polyspecificity: what does it matter?

Dimitrov JD, Pashov AD, Vassilev TL.

Adv Exp Med Biol. 2012;750:213-26. doi: 10.1007/978-1-4614-3461-0_16.

PMID:
22903677
47.

Thermodynamic analysis of the interaction of factor VIII with von Willebrand factor.

Dimitrov JD, Christophe OD, Kang J, Repessé Y, Delignat S, Kaveri SV, Lacroix-Desmazes S.

Biochemistry. 2012 May 22;51(20):4108-16. doi: 10.1021/bi300232d. Epub 2012 May 14.

PMID:
22559004
48.

Comment on Enhancement of the catalytic activity of a 27 kDa subtilisin-like enzyme from Bacillus amyloliquefaciens CH51 by in vitro mutagenesis.

Viqar B, Gopinath A, Dimitrov JD, Kang J.

J Agric Food Chem. 2012 Apr 25;60(16):4170-2. doi: 10.1021/jf2050729. Epub 2012 Apr 4. No abstract available.

PMID:
22475247
49.

Heme binds to factor VIII and inhibits its interaction with activated factor IX.

Repessé Y, Dimitrov JD, Peyron I, Farrokhi Moshai E, Kiger L, Dasgupta S, Delignat S, Marden MC, Kaveri SV, Lacroix-Desmazes S.

J Thromb Haemost. 2012 Jun;10(6):1062-71. doi: 10.1111/j.1538-7836.2012.04724.x.

50.

Important parameters for evaluation of antibody avidity by immunosorbent assay.

Dimitrov JD, Lacroix-Desmazes S, Kaveri SV.

Anal Biochem. 2011 Nov 1;418(1):149-51. doi: 10.1016/j.ab.2011.07.007. Epub 2011 Jul 26.

PMID:
21803020

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