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Items: 1 to 50 of 65

1.

The small GTPase Rab5c is a key regulator of trafficking of the CD93/Multimerin-2/β1 integrin complex in endothelial cell adhesion and migration.

Barbera S, Nardi F, Elia I, Realini G, Lugano R, Santucci A, Tosi GM, Dimberg A, Galvagni F, Orlandini M.

Cell Commun Signal. 2019 May 28;17(1):55. doi: 10.1186/s12964-019-0375-x.

2.

Vascular Targeting to Increase the Efficiency of Immune Checkpoint Blockade in Cancer.

Georganaki M, van Hooren L, Dimberg A.

Front Immunol. 2018 Dec 21;9:3081. doi: 10.3389/fimmu.2018.03081. eCollection 2018. Review.

3.

Osteoglycin - A switch from angiogenesis to T-cell recruitment?

Dimberg A.

EBioMedicine. 2018 Sep;35:22-23. doi: 10.1016/j.ebiom.2018.08.020. Epub 2018 Aug 17. No abstract available.

4.

Region-by-region analysis of PET, MRI, and histology in en bloc-resected oligodendrogliomas reveals intra-tumoral heterogeneity.

Roodakker KR, Alhuseinalkhudhur A, Al-Jaff M, Georganaki M, Zetterling M, Berntsson SG, Danfors T, Strand R, Edqvist PH, Dimberg A, Larsson EM, Smits A.

Eur J Nucl Med Mol Imaging. 2019 Mar;46(3):569-579. doi: 10.1007/s00259-018-4107-z. Epub 2018 Aug 14.

5.

Re-exploration for bleeding associated with increased incidence of the need for reintervention after coronary artery bypass graft surgery.

Dimberg A, Alström U, Janiec M.

Interact Cardiovasc Thorac Surg. 2019 Feb 1;28(2):214-221. doi: 10.1093/icvts/ivy245.

PMID:
30101308
6.

Bones in human CYP26B1 deficiency and rats with hypervitaminosis A phenocopy Vegfa overexpression.

Lind T, Lugano R, Gustafson AM, Norgård M, van Haeringen A, Dimberg A, Melhus H, Robertson SP, Andersson G.

Bone Rep. 2018 Jun 21;9:27-36. doi: 10.1016/j.bonr.2018.06.006. eCollection 2018 Dec.

7.

IDH mutation status is associated with distinct vascular gene expression signatures in lower-grade gliomas.

Zhang L, He L, Lugano R, Roodakker K, Bergqvist M, Smits A, Dimberg A.

Neuro Oncol. 2018 Oct 9;20(11):1505-1516. doi: 10.1093/neuonc/noy088.

8.

Higher Preoperative Plasma Thrombin Potential in Patients Undergoing Surgery for Aortic Stenosis Compared to Surgery for Stable Coronary Artery Disease.

Dimberg A, Alström U, Ståhle E, Christersson C.

Clin Appl Thromb Hemost. 2018 Nov;24(8):1282-1290. doi: 10.1177/1076029618776374. Epub 2018 May 16.

PMID:
29768939
9.

Consensus guidelines for the use and interpretation of angiogenesis assays.

Nowak-Sliwinska P, Alitalo K, Allen E, Anisimov A, Aplin AC, Auerbach R, Augustin HG, Bates DO, van Beijnum JR, Bender RHF, Bergers G, Bikfalvi A, Bischoff J, Böck BC, Brooks PC, Bussolino F, Cakir B, Carmeliet P, Castranova D, Cimpean AM, Cleaver O, Coukos G, Davis GE, De Palma M, Dimberg A, Dings RPM, Djonov V, Dudley AC, Dufton NP, Fendt SM, Ferrara N, Fruttiger M, Fukumura D, Ghesquière B, Gong Y, Griffin RJ, Harris AL, Hughes CCW, Hultgren NW, Iruela-Arispe ML, Irving M, Jain RK, Kalluri R, Kalucka J, Kerbel RS, Kitajewski J, Klaassen I, Kleinmann HK, Koolwijk P, Kuczynski E, Kwak BR, Marien K, Melero-Martin JM, Munn LL, Nicosia RF, Noel A, Nurro J, Olsson AK, Petrova TV, Pietras K, Pili R, Pollard JW, Post MJ, Quax PHA, Rabinovich GA, Raica M, Randi AM, Ribatti D, Ruegg C, Schlingemann RO, Schulte-Merker S, Smith LEH, Song JW, Stacker SA, Stalin J, Stratman AN, Van de Velde M, van Hinsbergh VWM, Vermeulen PB, Waltenberger J, Weinstein BM, Xin H, Yetkin-Arik B, Yla-Herttuala S, Yoder MC, Griffioen AW.

Angiogenesis. 2018 Aug;21(3):425-532. doi: 10.1007/s10456-018-9613-x. Review.

10.

CD93 promotes β1 integrin activation and fibronectin fibrillogenesis during tumor angiogenesis.

Lugano R, Vemuri K, Yu D, Bergqvist M, Smits A, Essand M, Johansson S, Dejana E, Dimberg A.

J Clin Invest. 2018 Aug 1;128(8):3280-3297. doi: 10.1172/JCI97459. Epub 2018 Jun 25.

11.

Erratum to: "No improvements in long-term outcome after coronary artery bypass grafting with arterial grafts as a second conduit: a Swedish nationwide registry study" [Eur J Cardiothorac Surg 2018;53(2):448-454].

Janiec M, Dimberg A, Nazari Shafti TZ, Lagerqvist B, Lindblom RPF.

Eur J Cardiothorac Surg. 2018 May 1;53(5):1098. doi: 10.1093/ejcts/ezy123. No abstract available.

PMID:
29534169
12.

Graft failure and recurrence of symptoms after coronary artery bypass grafting.

Janiec M, Nazari Shafti TZ, Dimberg A, Lagerqvist B, Lindblom RPF.

Scand Cardiovasc J. 2018 Jun;52(3):113-119. doi: 10.1080/14017431.2018.1442930. Epub 2018 Mar 6. Erratum in: Scand Cardiovasc J. 2018 Jun;52(3):170.

PMID:
29508655
13.

No improvements in long-term outcome after coronary artery bypass grafting with arterial grafts as a second conduit: a Swedish nationwide registry study.

Janiec M, Dimberg A, Nazari Shafti TZ, Lagerqvist B, Lindblom RPF.

Eur J Cardiothorac Surg. 2018 Feb 1;53(2):448-454. doi: 10.1093/ejcts/ezx280. Erratum in: Eur J Cardiothorac Surg. 2018 May 1;53(5):1098.

PMID:
28958083
14.

Pharmacological targeting of peptidylarginine deiminase 4 prevents cancer-associated kidney injury in mice.

Cedervall J, Dragomir A, Saupe F, Zhang Y, Ärnlöv J, Larsson E, Dimberg A, Larsson A, Olsson AK.

Oncoimmunology. 2017 Apr 20;6(8):e1320009. doi: 10.1080/2162402X.2017.1320009. eCollection 2017.

15.

Shaping the Tumor Stroma and Sparking Immune Activation by CD40 and 4-1BB Signaling Induced by an Armed Oncolytic Virus.

Eriksson E, Milenova I, Wenthe J, Ståhle M, Leja-Jarblad J, Ullenhag G, Dimberg A, Moreno R, Alemany R, Loskog A.

Clin Cancer Res. 2017 Oct 1;23(19):5846-5857. doi: 10.1158/1078-0432.CCR-17-0285. Epub 2017 May 23.

16.

The cancer-immunity cycle as rational design for synthetic cancer drugs: Novel DC vaccines and CAR T-cells.

Ramachandran M, Dimberg A, Essand M.

Semin Cancer Biol. 2017 Aug;45:23-35. doi: 10.1016/j.semcancer.2017.02.010. Epub 2017 Feb 28. Review.

17.

Pleiotrophin is a driver of vascular abnormalization in glioblastoma.

Zhang L, Dimberg A.

Mol Cell Oncol. 2016 Feb 18;3(6):e1141087. doi: 10.1080/23723556.2016.1141087. eCollection 2016.

18.

Activation of myeloid and endothelial cells by CD40L gene therapy supports T-cell expansion and migration into the tumor microenvironment.

Eriksson E, Moreno R, Milenova I, Liljenfeldt L, Dieterich LC, Christiansson L, Karlsson H, Ullenhag G, Mangsbo SM, Dimberg A, Alemany R, Loskog A.

Gene Ther. 2017 Feb;24(2):92-103. doi: 10.1038/gt.2016.80. Epub 2016 Dec 1.

19.

Local checkpoint inhibition of CTLA-4 as a monotherapy or in combination with anti-PD1 prevents the growth of murine bladder cancer.

van Hooren L, Sandin LC, Moskalev I, Ellmark P, Dimberg A, Black P, Tötterman TH, Mangsbo SM.

Eur J Immunol. 2017 Feb;47(2):385-393. doi: 10.1002/eji.201646583. Epub 2016 Dec 13.

20.

ANLN is a prognostic biomarker independent of Ki-67 and essential for cell cycle progression in primary breast cancer.

Magnusson K, Gremel G, Rydén L, Pontén V, Uhlén M, Dimberg A, Jirström K, Pontén F.

BMC Cancer. 2016 Nov 18;16(1):904.

21.

Pleiotrophin enhances PDGFB-induced gliomagenesis through increased proliferation of neural progenitor cells.

Zhang L, Laaniste L, Jiang Y, Alafuzoff I, Uhrbom L, Dimberg A.

Oncotarget. 2016 Dec 6;7(49):80382-80390. doi: 10.18632/oncotarget.12983.

22.

Safe and Effective Treatment of Experimental Neuroblastoma and Glioblastoma Using Systemically Delivered Triple MicroRNA-Detargeted Oncolytic Semliki Forest Virus.

Ramachandran M, Yu D, Dyczynski M, Baskaran S, Zhang L, Lulla A, Lulla V, Saul S, Nelander S, Dimberg A, Merits A, Leja-Jarblad J, Essand M.

Clin Cancer Res. 2017 Mar 15;23(6):1519-1530. doi: 10.1158/1078-0432.CCR-16-0925. Epub 2016 Sep 16.

23.

Heparanase Promotes Glioma Progression and Is Inversely Correlated with Patient Survival.

Kundu S, Xiong A, Spyrou A, Wicher G, Marinescu VD, Edqvist PD, Zhang L, Essand M, Dimberg A, Smits A, Ilan N, Vlodavsky I, Li JP, Forsberg-Nilsson K.

Mol Cancer Res. 2016 Dec;14(12):1243-1253. Epub 2016 Aug 26. Erratum in: Mol Cancer Res. 2018 Apr;16(4):740-741.

24.

Sunitinib enhances the antitumor responses of agonistic CD40-antibody by reducing MDSCs and synergistically improving endothelial activation and T-cell recruitment.

van Hooren L, Georganaki M, Huang H, Mangsbo SM, Dimberg A.

Oncotarget. 2016 Jul 1;7(31):50277-50289. doi: 10.18632/oncotarget.10364.

25.

Tumor-induced neutrophil extracellular traps-drivers of systemic inflammation and vascular dysfunction.

Cedervall J, Dimberg A, Olsson AK.

Oncoimmunology. 2015 Oct 29;5(3):e1098803. eCollection 2016 Mar.

26.

Tumor-Induced Local and Systemic Impact on Blood Vessel Function.

Cedervall J, Dimberg A, Olsson AK.

Mediators Inflamm. 2015;2015:418290. doi: 10.1155/2015/418290. Epub 2015 Dec 7. Review.

27.

Pleiotrophin promotes vascular abnormalization in gliomas and correlates with poor survival in patients with astrocytomas.

Zhang L, Kundu S, Feenstra T, Li X, Jin C, Laaniste L, El Hassan TE, Ohlin KE, Yu D, Olofsson T, Olsson AK, Pontén F, Magnusson PU, Nilsson KF, Essand M, Smits A, Dieterich LC, Dimberg A.

Sci Signal. 2015 Dec 8;8(406):ra125. doi: 10.1126/scisignal.aaa1690.

PMID:
26645582
28.

Elevated expression of the C-type lectin CD93 in the glioblastoma vasculature regulates cytoskeletal rearrangements that enhance vessel function and reduce host survival.

Langenkamp E, Zhang L, Lugano R, Huang H, Elhassan TE, Georganaki M, Bazzar W, Lööf J, Trendelenburg G, Essand M, Pontén F, Smits A, Dimberg A.

Cancer Res. 2015 Nov 1;75(21):4504-16. doi: 10.1158/0008-5472.CAN-14-3636. Epub 2015 Sep 11.

29.

Neutrophil Extracellular Traps Accumulate in Peripheral Blood Vessels and Compromise Organ Function in Tumor-Bearing Animals.

Cedervall J, Zhang Y, Huang H, Zhang L, Femel J, Dimberg A, Olsson AK.

Cancer Res. 2015 Jul 1;75(13):2653-62. doi: 10.1158/0008-5472.CAN-14-3299. Epub 2015 Jun 12.

30.

Next-generation pathology--surveillance of tumor microecology.

Koos B, Kamali-Moghaddam M, David L, Sobrinho-Simões M, Dimberg A, Nilsson M, Wählby C, Söderberg O.

J Mol Biol. 2015 Jun 5;427(11):2013-22. doi: 10.1016/j.jmb.2015.02.017. Epub 2015 Feb 26. Review.

31.

The glioblastoma vasculature as a target for cancer therapy.

Dimberg A.

Biochem Soc Trans. 2014 Dec;42(6):1647-52. doi: 10.1042/BST20140278. Review.

PMID:
25399584
32.

VEGF suppresses T-lymphocyte infiltration in the tumor microenvironment through inhibition of NF-κB-induced endothelial activation.

Huang H, Langenkamp E, Georganaki M, Loskog A, Fuchs PF, Dieterich LC, Kreuger J, Dimberg A.

FASEB J. 2015 Jan;29(1):227-38. doi: 10.1096/fj.14-250985. Epub 2014 Oct 31.

PMID:
25361735
33.

Therapeutic vaccination against fibronectin ED-A attenuates progression of metastatic breast cancer.

Femel J, Huijbers EJ, Saupe F, Cedervall J, Zhang L, Roswall P, Larsson E, Olofsson H, Pietras K, Dimberg A, Hellman L, Olsson AK.

Oncotarget. 2014 Dec 15;5(23):12418-27.

34.

CD40L gene therapy tilts the myeloid cell profile and promotes infiltration of activated T lymphocytes.

Liljenfeldt L, Dieterich LC, Dimberg A, Mangsbo SM, Loskog AS.

Cancer Gene Ther. 2014 Mar;21(3):95-102. doi: 10.1038/cgt.2014.2. Epub 2014 Jan 31.

PMID:
24481488
35.

Subtyping of gliomas of various WHO grades by the application of immunohistochemistry.

Popova SN, Bergqvist M, Dimberg A, Edqvist PH, Ekman S, Hesselager G, Ponten F, Smits A, Sooman L, Alafuzoff I.

Histopathology. 2014 Feb;64(3):365-79. doi: 10.1111/his.12252. Epub 2013 Nov 5.

36.

αB-crystallin/HspB5 regulates endothelial-leukocyte interactions by enhancing NF-κB-induced up-regulation of adhesion molecules ICAM-1, VCAM-1 and E-selectin.

Dieterich LC, Huang H, Massena S, Golenhofen N, Phillipson M, Dimberg A.

Angiogenesis. 2013 Oct;16(4):975-83. doi: 10.1007/s10456-013-9367-4. Epub 2013 Aug 9.

37.

VE-PTP regulates VEGFR2 activity in stalk cells to establish endothelial cell polarity and lumen formation.

Hayashi M, Majumdar A, Li X, Adler J, Sun Z, Vertuani S, Hellberg C, Mellberg S, Koch S, Dimberg A, Koh GY, Dejana E, Belting HG, Affolter M, Thurston G, Holmgren L, Vestweber D, Claesson-Welsh L.

Nat Commun. 2013;4:1672. doi: 10.1038/ncomms2683.

38.

αB-Crystallin regulates expansion of CD11b⁺Gr-1⁺ immature myeloid cells during tumor progression.

Dieterich LC, Schiller P, Huang H, Wawrousek EF, Loskog A, Wanders A, Moons L, Dimberg A.

FASEB J. 2013 Jan;27(1):151-62. doi: 10.1096/fj.12-213017. Epub 2012 Oct 2.

39.

Stat1 activation attenuates IL-6 induced Stat3 activity but does not alter apoptosis sensitivity in multiple myeloma.

Dimberg LY, Dimberg A, Ivarsson K, Fryknäs M, Rickardson L, Tobin G, Ekman S, Larsson R, Gullberg U, Nilsson K, Öberg F, Wiklund HJ.

BMC Cancer. 2012 Jul 28;12:318. doi: 10.1186/1471-2407-12-318.

40.

Transcriptional profiling of human glioblastoma vessels indicates a key role of VEGF-A and TGFβ2 in vascular abnormalization.

Dieterich LC, Mellberg S, Langenkamp E, Zhang L, Zieba A, Salomäki H, Teichert M, Huang H, Edqvist PH, Kraus T, Augustin HG, Olofsson T, Larsson E, Söderberg O, Molema G, Pontén F, Georgii-Hemming P, Alafuzoff I, Dimberg A.

J Pathol. 2012 Nov;228(3):378-90. doi: 10.1002/path.4072. Epub 2012 Aug 31.

PMID:
22786655
41.

GABA-A channel subunit expression in human glioma correlates with tumor histology and clinical outcome.

Smits A, Jin Z, Elsir T, Pedder H, Nistér M, Alafuzoff I, Dimberg A, Edqvist PH, Pontén F, Aronica E, Birnir B.

PLoS One. 2012;7(5):e37041. doi: 10.1371/journal.pone.0037041. Epub 2012 May 17.

42.

Paladin (X99384) is expressed in the vasculature and shifts from endothelial to vascular smooth muscle cells during mouse development.

Wallgard E, Nitzsche A, Larsson J, Guo X, Dieterich LC, Dimberg A, Olofsson T, Pontén FC, Mäkinen T, Kalén M, Hellström M.

Dev Dyn. 2012 Apr;241(4):770-86. doi: 10.1002/dvdy.23753. Epub 2012 Feb 21.

43.

Vascular endothelial growth factor receptor 2 (VEGFR-2) signalling activity in paediatric pilocytic astrocytoma is restricted to tumour endothelial cells.

Sikkema AH, de Bont ES, Molema G, Dimberg A, Zwiers PJ, Diks SH, Hoving EW, Kamps WA, Peppelenbosch MP, den Dunnen WF.

Neuropathol Appl Neurobiol. 2011 Aug;37(5):538-48. doi: 10.1111/j.1365-2990.2011.01160.x.

PMID:
21208252
44.

Chemokines in angiogenesis.

Dimberg A.

Curr Top Microbiol Immunol. 2010;341:59-80. doi: 10.1007/82_2010_21. Review.

PMID:
20373091
45.

Activated platelets provide a functional microenvironment for the antiangiogenic fragment of histidine-rich glycoprotein.

Thulin A, Ringvall M, Dimberg A, Kårehed K, Väisänen T, Väisänen MR, Hamad O, Wang J, Bjerkvig R, Nilsson B, Pihlajaniemi T, Akerud H, Pietras K, Jahnen-Dechent W, Siegbahn A, Olsson AK.

Mol Cancer Res. 2009 Nov;7(11):1792-802. doi: 10.1158/1541-7786.MCR-09-0094. Epub 2009 Nov 10.

46.

Transcriptional profiling reveals a critical role for tyrosine phosphatase VE-PTP in regulation of VEGFR2 activity and endothelial cell morphogenesis.

Mellberg S, Dimberg A, Bahram F, Hayashi M, Rennel E, Ameur A, Westholm JO, Larsson E, Lindahl P, Cross MJ, Claesson-Welsh L.

FASEB J. 2009 May;23(5):1490-502. doi: 10.1096/fj.08-123810. Epub 2009 Jan 9.

PMID:
19136612
47.

Ninein is expressed in the cytoplasm of angiogenic tip-cells and regulates tubular morphogenesis of endothelial cells.

Matsumoto T, Schiller P, Dieterich LC, Bahram F, Iribe Y, Hellman U, Wikner C, Chan G, Claesson-Welsh L, Dimberg A.

Arterioscler Thromb Vasc Biol. 2008 Dec;28(12):2123-30. doi: 10.1161/ATVBAHA.108.169128. Epub 2008 Sep 4.

PMID:
18772498
48.

alphaB-crystallin promotes tumor angiogenesis by increasing vascular survival during tube morphogenesis.

Dimberg A, Rylova S, Dieterich LC, Olsson AK, Schiller P, Wikner C, Bohman S, Botling J, Lukinius A, Wawrousek EF, Claesson-Welsh L.

Blood. 2008 Feb 15;111(4):2015-23. Epub 2007 Dec 6.

49.

FGFR-1 regulates angiogenesis through cytokines interleukin-4 and pleiotrophin.

Magnusson PU, Dimberg A, Mellberg S, Lukinius A, Claesson-Welsh L.

Blood. 2007 Dec 15;110(13):4214-22. Epub 2007 Sep 17.

50.

Lentiviral rescue of vascular endothelial growth factor receptor-2 expression in flk1-/- embryonic stem cells shows early priming of endothelial precursors.

Li X, Edholm D, Lanner F, Breier G, Farnebo F, Dimberg A, Claesson-Welsh L.

Stem Cells. 2007 Dec;25(12):2987-95. Epub 2007 Aug 16.

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