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Items: 1 to 50 of 60

1.

Tendon contains more stem cells than bone at the rotator cuff repair site.

Campbell TM, Lapner P, Dilworth FJ, Sheikh MA, Laneuville O, Uhthoff H, Trudel G.

J Shoulder Elbow Surg. 2019 Apr 26. pii: S1058-2746(19)30116-8. doi: 10.1016/j.jse.2019.02.008. [Epub ahead of print]

PMID:
31036422
2.

Polycomb/Trithorax Antagonism: Cellular Memory in Stem Cell Fate and Function.

Brand M, Nakka K, Zhu J, Dilworth FJ.

Cell Stem Cell. 2019 Apr 4;24(4):518-533. doi: 10.1016/j.stem.2019.03.005. Review.

PMID:
30951661
3.

Targeting the MTF2-MDM2 Axis Sensitizes Refractory Acute Myeloid Leukemia to Chemotherapy.

Maganti HB, Jrade H, Cafariello C, Manias Rothberg JL, Porter CJ, Yockell-Lelièvre J, Battaion HL, Khan ST, Howard JP, Li Y, Grzybowski AT, Sabri E, Ruthenburg AJ, Dilworth FJ, Perkins TJ, Sabloff M, Ito CY, Stanford WL.

Cancer Discov. 2018 Nov;8(11):1376-1389. doi: 10.1158/2159-8290.CD-17-0841. Epub 2018 Aug 16.

PMID:
30115703
4.

Diversification of the muscle proteome through alternative splicing.

Nakka K, Ghigna C, Gabellini D, Dilworth FJ.

Skelet Muscle. 2018 Mar 6;8(1):8. doi: 10.1186/s13395-018-0152-3. Review.

5.

Epigenetic Regulation of Adult Myogenesis.

Robinson DCL, Dilworth FJ.

Curr Top Dev Biol. 2018;126:235-284. doi: 10.1016/bs.ctdb.2017.08.002. Epub 2017 Sep 28. Review.

PMID:
29305001
6.

Activating transcription factor 3 promotes loss of the acinar cell phenotype in response to cerulein-induced pancreatitis in mice.

Fazio EN, Young CC, Toma J, Levy M, Berger KR, Johnson CL, Mehmood R, Swan P, Chu A, Cregan SP, Dilworth FJ, Howlett CJ, Pin CL.

Mol Biol Cell. 2017 Sep 1;28(18):2347-2359. doi: 10.1091/mbc.E17-04-0254. Epub 2017 Jul 12.

7.

Reprogramming progeria fibroblasts re-establishes a normal epigenetic landscape.

Chen Z, Chang WY, Etheridge A, Strickfaden H, Jin Z, Palidwor G, Cho JH, Wang K, Kwon SY, Doré C, Raymond A, Hotta A, Ellis J, Kandel RA, Dilworth FJ, Perkins TJ, Hendzel MJ, Galas DJ, Stanford WL.

Aging Cell. 2017 Aug;16(4):870-887. doi: 10.1111/acel.12621. Epub 2017 Jun 8.

8.

Splicing of Ezh1 gets muscle out of stressful situations.

Brand M, Dilworth FJ.

Nat Struct Mol Biol. 2017 May 4;24(5):435-437. doi: 10.1038/nsmb.3406. No abstract available.

PMID:
28471428
9.

Polycomb repressive complex 1 provides a molecular explanation for repeat copy number dependency in FSHD muscular dystrophy.

Casa V, Runfola V, Micheloni S, Aziz A, Dilworth FJ, Gabellini D.

Hum Mol Genet. 2017 Feb 15;26(4):753-767. doi: 10.1093/hmg/ddw426.

10.

UTX demethylase activity is required for satellite cell-mediated muscle regeneration.

Faralli H, Wang C, Nakka K, Benyoucef A, Sebastian S, Zhuang L, Chu A, Palii CG, Liu C, Camellato B, Brand M, Ge K, Dilworth FJ.

J Clin Invest. 2016 Apr 1;126(4):1555-65. doi: 10.1172/JCI83239. Epub 2016 Mar 21.

11.

Chromatin-wide and transcriptome profiling integration uncovers p38α MAPK as a global regulator of skeletal muscle differentiation.

Segalés J, Islam AB, Kumar R, Liu QC, Sousa-Victor P, Dilworth FJ, Ballestar E, Perdiguero E, Muñoz-Cánoves P.

Skelet Muscle. 2016 Mar 15;6:9. doi: 10.1186/s13395-016-0074-x. eCollection 2016.

12.

UTX inhibition as selective epigenetic therapy against TAL1-driven T-cell acute lymphoblastic leukemia.

Benyoucef A, Palii CG, Wang C, Porter CJ, Chu A, Dai F, Tremblay V, Rakopoulos P, Singh K, Huang S, Pflumio F, Hébert J, Couture JF, Perkins TJ, Ge K, Dilworth FJ, Brand M.

Genes Dev. 2016 Mar 1;30(5):508-21. doi: 10.1101/gad.276790.115.

13.

Compacting Chromatin to Ensure Muscle Satellite Cell Quiescence.

Li Y, Dilworth FJ.

Cell Stem Cell. 2016 Feb 4;18(2):162-4. doi: 10.1016/j.stem.2016.01.009.

14.

Nuclear matrix-associated protein SMAR1 regulates alternative splicing via HDAC6-mediated deacetylation of Sam68.

Nakka KK, Chaudhary N, Joshi S, Bhat J, Singh K, Chatterjee S, Malhotra R, De A, Santra MK, Dilworth FJ, Chattopadhyay S.

Proc Natl Acad Sci U S A. 2015 Jun 30;112(26):E3374-83. doi: 10.1073/pnas.1418603112. Epub 2015 Jun 15.

15.

A KAP1 phosphorylation switch controls MyoD function during skeletal muscle differentiation.

Singh K, Cassano M, Planet E, Sebastian S, Jang SM, Sohi G, Faralli H, Choi J, Youn HD, Dilworth FJ, Trono D.

Genes Dev. 2015 Mar 1;29(5):513-25. doi: 10.1101/gad.254532.114.

16.

Rbfox proteins regulate tissue-specific alternative splicing of Mef2D required for muscle differentiation.

Runfola V, Sebastian S, Dilworth FJ, Gabellini D.

J Cell Sci. 2015 Feb 15;128(4):631-7. doi: 10.1242/jcs.161059. Epub 2015 Jan 20.

17.

Noncoding RNAs as epigenetic mediators of skeletal muscle regeneration.

Sohi G, Dilworth FJ.

FEBS J. 2015 May;282(9):1630-46. doi: 10.1111/febs.13170. Epub 2015 Jan 12. Review.

18.

Trichostatin A enhances vascular repair by injected human endothelial progenitors through increasing the expression of TAL1-dependent genes.

Palii CG, Vulesevic B, Fraineau S, Pranckeviciene E, Griffith AJ, Chu A, Faralli H, Li Y, McNeill B, Sun J, Perkins TJ, Dilworth FJ, Perez-Iratxeta C, Suuronen EJ, Allan DS, Brand M.

Cell Stem Cell. 2014 May 1;14(5):644-57. doi: 10.1016/j.stem.2014.03.003.

19.

Dystrophic muscle environment induces changes in cell plasticity.

Faralli H, Dilworth FJ.

Genes Dev. 2014 Apr 15;28(8):809-11. doi: 10.1101/gad.241182.114.

20.

Six1 regulates MyoD expression in adult muscle progenitor cells.

Liu Y, Chakroun I, Yang D, Horner E, Liang J, Aziz A, Chu A, De Repentigny Y, Dilworth FJ, Kothary R, Blais A.

PLoS One. 2013 Jun 28;8(6):e67762. doi: 10.1371/journal.pone.0067762. Print 2013.

21.

Tissue-specific splicing of a ubiquitously expressed transcription factor is essential for muscle differentiation.

Sebastian S, Faralli H, Yao Z, Rakopoulos P, Palii C, Cao Y, Singh K, Liu QC, Chu A, Aziz A, Brand M, Tapscott SJ, Dilworth FJ.

Genes Dev. 2013 Jun 1;27(11):1247-59. doi: 10.1101/gad.215400.113. Epub 2013 May 30.

22.

Chaperoning RNA Polymerase II through repressive chromatin.

Faralli H, Dilworth FJ.

EMBO J. 2013 Apr 17;32(8):1067-8. doi: 10.1038/emboj.2013.64. Epub 2013 Mar 15. No abstract available.

23.

Differential modulation of cell cycle progression distinguishes members of the myogenic regulatory factor family of transcription factors.

Singh K, Dilworth FJ.

FEBS J. 2013 Sep;280(17):3991-4003. doi: 10.1111/febs.12188. Epub 2013 Mar 8. Review.

24.

Maintenance of gene silencing by the coordinate action of the H3K9 methyltransferase G9a/KMT1C and the H3K4 demethylase Jarid1a/KDM5A.

Chaturvedi CP, Somasundaram B, Singh K, Carpenedo RL, Stanford WL, Dilworth FJ, Brand M.

Proc Natl Acad Sci U S A. 2012 Nov 13;109(46):18845-50. doi: 10.1073/pnas.1213951109. Epub 2012 Oct 29.

25.

Comparative expression profiling identifies differential roles for Myogenin and p38α MAPK signaling in myogenesis.

Liu QC, Zha XH, Faralli H, Yin H, Louis-Jeune C, Perdiguero E, Pranckeviciene E, Muñoz-Cànoves P, Rudnicki MA, Brand M, Perez-Iratxeta C, Dilworth FJ.

J Mol Cell Biol. 2012 Dec;4(6):386-97. doi: 10.1093/jmcb/mjs045. Epub 2012 Jul 30.

26.

Turning on myogenin in muscle: a paradigm for understanding mechanisms of tissue-specific gene expression.

Faralli H, Dilworth FJ.

Comp Funct Genomics. 2012;2012:836374. doi: 10.1155/2012/836374. Epub 2012 Jun 28.

27.

GSK3 temporally regulates neurogenin 2 proneural activity in the neocortex.

Li S, Mattar P, Zinyk D, Singh K, Chaturvedi CP, Kovach C, Dixit R, Kurrasch DM, Ma YC, Chan JA, Wallace V, Dilworth FJ, Brand M, Schuurmans C.

J Neurosci. 2012 Jun 6;32(23):7791-805. doi: 10.1523/JNEUROSCI.1309-12.2012.

28.

The origin and fate of muscle satellite cells.

Aziz A, Sebastian S, Dilworth FJ.

Stem Cell Rev. 2012 Jun;8(2):609-22. doi: 10.1007/s12015-012-9352-0. Review.

PMID:
22278133
29.

Signal-dependent incorporation of MyoD-BAF60c into Brg1-based SWI/SNF chromatin-remodelling complex.

Forcales SV, Albini S, Giordani L, Malecova B, Cignolo L, Chernov A, Coutinho P, Saccone V, Consalvi S, Williams R, Wang K, Wu Z, Baranovskaya S, Miller A, Dilworth FJ, Puri PL.

EMBO J. 2012 Jan 18;31(2):301-16. doi: 10.1038/emboj.2011.391. Epub 2011 Nov 8.

30.

Redirecting traffic in the nucleus.

Singh K, Dilworth FJ.

Dev Cell. 2011 Sep 13;21(3):390-2. doi: 10.1016/j.devcel.2011.08.025.

31.

Teashirt-3, a novel regulator of muscle differentiation, associates with BRG1-associated factor 57 (BAF57) to inhibit myogenin gene expression.

Faralli H, Martin E, Coré N, Liu QC, Filippi P, Dilworth FJ, Caubit X, Fasano L.

J Biol Chem. 2011 Jul 1;286(26):23498-510. doi: 10.1074/jbc.M110.206003. Epub 2011 May 4.

32.

Epigenetic regulation of satellite cell activation during muscle regeneration.

Dilworth FJ, Blais A.

Stem Cell Res Ther. 2011 Apr 19;2(2):18. doi: 10.1186/scrt59. Review.

33.

Constitutive heterochromatin reorganization during somatic cell reprogramming.

Fussner E, Djuric U, Strauss M, Hotta A, Perez-Iratxeta C, Lanner F, Dilworth FJ, Ellis J, Bazett-Jones DP.

EMBO J. 2011 May 4;30(9):1778-89. doi: 10.1038/emboj.2011.96. Epub 2011 Apr 5.

34.

Differential genomic targeting of the transcription factor TAL1 in alternate haematopoietic lineages.

Palii CG, Perez-Iratxeta C, Yao Z, Cao Y, Dai F, Davison J, Atkins H, Allan D, Dilworth FJ, Gentleman R, Tapscott SJ, Brand M.

EMBO J. 2011 Feb 2;30(3):494-509. doi: 10.1038/emboj.2010.342. Epub 2010 Dec 21.

35.

Regulating a master regulator: establishing tissue-specific gene expression in skeletal muscle.

Aziz A, Liu QC, Dilworth FJ.

Epigenetics. 2010 Nov-Dec;5(8):691-5. doi: 10.4161/epi.5.8.13045. Epub 2010 Nov 1. Review.

36.

UTX mediates demethylation of H3K27me3 at muscle-specific genes during myogenesis.

Seenundun S, Rampalli S, Liu QC, Aziz A, Palii C, Hong S, Blais A, Brand M, Ge K, Dilworth FJ.

EMBO J. 2010 Apr 21;29(8):1401-11. doi: 10.1038/emboj.2010.37. Epub 2010 Mar 18.

37.

Caspase 3/caspase-activated DNase promote cell differentiation by inducing DNA strand breaks.

Larsen BD, Rampalli S, Burns LE, Brunette S, Dilworth FJ, Megeney LA.

Proc Natl Acad Sci U S A. 2010 Mar 2;107(9):4230-5. doi: 10.1073/pnas.0913089107. Epub 2010 Feb 16.

38.

Dual role for the methyltransferase G9a in the maintenance of beta-globin gene transcription in adult erythroid cells.

Chaturvedi CP, Hosey AM, Palii C, Perez-Iratxeta C, Nakatani Y, Ranish JA, Dilworth FJ, Brand M.

Proc Natl Acad Sci U S A. 2009 Oct 27;106(43):18303-8. doi: 10.1073/pnas.0906769106. Epub 2009 Oct 12.

39.

MyoD and E-protein heterodimers switch rhabdomyosarcoma cells from an arrested myoblast phase to a differentiated state.

Yang Z, MacQuarrie KL, Analau E, Tyler AE, Dilworth FJ, Cao Y, Diede SJ, Tapscott SJ.

Genes Dev. 2009 Mar 15;23(6):694-707. doi: 10.1101/gad.1765109.

40.
41.

Pax7 activates myogenic genes by recruitment of a histone methyltransferase complex.

McKinnell IW, Ishibashi J, Le Grand F, Punch VG, Addicks GC, Greenblatt JF, Dilworth FJ, Rudnicki MA.

Nat Cell Biol. 2008 Jan;10(1):77-84. Epub 2007 Dec 9.

42.

p38 MAPK signaling regulates recruitment of Ash2L-containing methyltransferase complexes to specific genes during differentiation.

Rampalli S, Li L, Mak E, Ge K, Brand M, Tapscott SJ, Dilworth FJ.

Nat Struct Mol Biol. 2007 Dec;14(12):1150-6. Epub 2007 Nov 18.

43.

Activator-mediated recruitment of the MLL2 methyltransferase complex to the beta-globin locus.

Demers C, Chaturvedi CP, Ranish JA, Juban G, Lai P, Morle F, Aebersold R, Dilworth FJ, Groudine M, Brand M.

Mol Cell. 2007 Aug 17;27(4):573-84.

44.

The RNA helicases p68/p72 and the noncoding RNA SRA are coregulators of MyoD and skeletal muscle differentiation.

Caretti G, Schiltz RL, Dilworth FJ, Di Padova M, Zhao P, Ogryzko V, Fuller-Pace FV, Hoffman EP, Tapscott SJ, Sartorelli V.

Dev Cell. 2006 Oct;11(4):547-60.

45.

PARP-1 determines specificity in a retinoid signaling pathway via direct modulation of mediator.

Pavri R, Lewis B, Kim TK, Dilworth FJ, Erdjument-Bromage H, Tempst P, de Murcia G, Evans R, Chambon P, Reinberg D.

Mol Cell. 2005 Apr 1;18(1):83-96.

46.

A MyoD-generated feed-forward circuit temporally patterns gene expression during skeletal muscle differentiation.

Penn BH, Bergstrom DA, Dilworth FJ, Bengal E, Tapscott SJ.

Genes Dev. 2004 Oct 1;18(19):2348-53.

47.

In vitro transcription system delineates the distinct roles of the coactivators pCAF and p300 during MyoD/E47-dependent transactivation.

Dilworth FJ, Seaver KJ, Fishburn AL, Htet SL, Tapscott SJ.

Proc Natl Acad Sci U S A. 2004 Aug 10;101(32):11593-8. Epub 2004 Aug 2.

48.

The novel transcription factor e(y)2 interacts with TAF(II)40 and potentiates transcription activation on chromatin templates.

Georgieva S, Nabirochkina E, Dilworth FJ, Eickhoff H, Becker P, Tora L, Georgiev P, Soldatov A.

Mol Cell Biol. 2001 Aug;21(15):5223-31.

50.

UV-damaged DNA-binding protein in the TFTC complex links DNA damage recognition to nucleosome acetylation.

Brand M, Moggs JG, Oulad-Abdelghani M, Lejeune F, Dilworth FJ, Stevenin J, Almouzni G, Tora L.

EMBO J. 2001 Jun 15;20(12):3187-96.

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