Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 108

1.

Blood-brain barrier dysfunction in aging induces hyperactivation of TGFβ signaling and chronic yet reversible neural dysfunction.

Senatorov VV Jr, Friedman AR, Milikovsky DZ, Ofer J, Saar-Ashkenazy R, Charbash A, Jahan N, Chin G, Mihaly E, Lin JM, Ramsay HJ, Moghbel A, Preininger MK, Eddings CR, Harrison HV, Patel R, Shen Y, Ghanim H, Sheng H, Veksler R, Sudmant PH, Becker A, Hart B, Rogawski MA, Dillin A, Friedman A, Kaufer D.

Sci Transl Med. 2019 Dec 4;11(521). pii: eaaw8283. doi: 10.1126/scitranslmed.aaw8283.

PMID:
31801886
2.

The Hyaluronidase, TMEM2, Promotes ER Homeostasis and Longevity Independent of the UPRER.

Schinzel RT, Higuchi-Sanabria R, Shalem O, Moehle EA, Webster BM, Joe L, Bar-Ziv R, Frankino PA, Durieux J, Pender C, Kelet N, Kumar SS, Savalia N, Chi H, Simic M, Nguyen NT, Dillin A.

Cell. 2019 Nov 27;179(6):1306-1318.e18. doi: 10.1016/j.cell.2019.10.018. Epub 2019 Nov 21.

PMID:
31761535
3.

X Chromosome Domain Architecture Regulates Caenorhabditis elegans Lifespan but Not Dosage Compensation.

Anderson EC, Frankino PA, Higuchi-Sanabria R, Yang Q, Bian Q, Podshivalova K, Shin A, Kenyon C, Dillin A, Meyer BJ.

Dev Cell. 2019 Oct 21;51(2):192-207.e6. doi: 10.1016/j.devcel.2019.08.004. Epub 2019 Sep 5.

PMID:
31495695
4.

Evolutionary Comeuppance: Mitochondrial Stress Awakens the Remnants of Ancient Bacterial Warfare.

Frankino PA, Moehle EA, Dillin A.

Cell Metab. 2019 May 7;29(5):1015-1017. doi: 10.1016/j.cmet.2019.04.007.

PMID:
31067444
5.

Transient activation of the UPRER is an essential step in the acquisition of pluripotency during reprogramming.

Simic MS, Moehle EA, Schinzel RT, Lorbeer FK, Halloran JJ, Heydari K, Sanchez M, Jullié D, Hockemeyer D, Dillin A.

Sci Adv. 2019 Apr 10;5(4):eaaw0025. doi: 10.1126/sciadv.aaw0025. eCollection 2019 Apr.

6.

Intercellular communication is required for trap formation in the nematode-trapping fungus Duddingtonia flagrans.

Youssar L, Wernet V, Hensel N, Yu X, Hildebrand HG, Schreckenberger B, Kriegler M, Hetzer B, Frankino P, Dillin A, Fischer R.

PLoS Genet. 2019 Mar 27;15(3):e1008029. doi: 10.1371/journal.pgen.1008029. eCollection 2019 Mar.

7.

Vive ut Numquam Moriturus: Tweaking Translational Control to Regulate Longevity.

Bar-Ziv R, Nguyen NT, Dillin A.

Mol Cell. 2019 Feb 21;73(4):643-644. doi: 10.1016/j.molcel.2019.02.006.

PMID:
30794792
8.

Spatial regulation of the actin cytoskeleton by HSF-1 during aging.

Higuchi-Sanabria R, Paul JW 3rd, Durieux J, Benitez C, Frankino PA, Tronnes SU, Garcia G, Daniele JR, Monshietehadi S, Dillin A.

Mol Biol Cell. 2018 Oct 15;29(21):2522-2527. doi: 10.1091/mbc.E18-06-0362. Epub 2018 Aug 22.

9.

Cellular clearance of circulating transthyretin decreases cell-nonautonomous proteotoxicity in Caenorhabditis elegans.

Madhivanan K, Greiner ER, Alves-Ferreira M, Soriano-Castell D, Rouzbeh N, Aguirre CA, Paulsson JF, Chapman J, Jiang X, Ooi FK, Lemos C, Dillin A, Prahlad V, Kelly JW, Encalada SE.

Proc Natl Acad Sci U S A. 2018 Aug 14;115(33):E7710-E7719. doi: 10.1073/pnas.1801117115. Epub 2018 Jul 30. Erratum in: Proc Natl Acad Sci U S A. 2019 Feb 19;116(8):3338.

10.

The Mitochondrial Unfolded Protein Response Is Mediated Cell-Non-autonomously by Retromer-Dependent Wnt Signaling.

Zhang Q, Wu X, Chen P, Liu L, Xin N, Tian Y, Dillin A.

Cell. 2018 Aug 9;174(4):870-883.e17. doi: 10.1016/j.cell.2018.06.029. Epub 2018 Jul 26.

11.

Mitochondrial Subtype Identification and Characterization.

Daniele JR, Heydari K, Dillin A.

Curr Protoc Cytom. 2018 Jul;85(1):e41. doi: 10.1002/cpcy.41. Epub 2018 Jun 26.

12.

The Lysosome, Elixir of Neural Stem Cell Youth.

Simic MS, Dillin A.

Cell Stem Cell. 2018 May 3;22(5):619-620. doi: 10.1016/j.stem.2018.04.017.

13.

Mitochondrial proteostasis in the context of cellular and organismal health and aging.

Moehle EA, Shen K, Dillin A.

J Biol Chem. 2019 Apr 5;294(14):5396-5407. doi: 10.1074/jbc.TM117.000893. Epub 2018 Apr 5. Review.

14.

Visible light reduces C. elegans longevity.

De Magalhaes Filho CD, Henriquez B, Seah NE, Evans RM, Lapierre LR, Dillin A.

Nat Commun. 2018 Mar 2;9(1):927. doi: 10.1038/s41467-018-02934-5.

15.

A Futile Battle? Protein Quality Control and the Stress of Aging.

Higuchi-Sanabria R, Frankino PA, Paul JW 3rd, Tronnes SU, Dillin A.

Dev Cell. 2018 Jan 22;44(2):139-163. doi: 10.1016/j.devcel.2017.12.020. Review.

16.

"High-Throughput Characterization of Region-Specific Mitochondrial Function and Morphology".

Daniele JR, Esping DJ, Garcia G, Parsons LS, Arriaga EA, Dillin A.

Sci Rep. 2017 Jul 27;7(1):6749. doi: 10.1038/s41598-017-05152-z.

17.

DGAT1-Dependent Lipid Droplet Biogenesis Protects Mitochondrial Function during Starvation-Induced Autophagy.

Nguyen TB, Louie SM, Daniele JR, Tran Q, Dillin A, Zoncu R, Nomura DK, Olzmann JA.

Dev Cell. 2017 Jul 10;42(1):9-21.e5. doi: 10.1016/j.devcel.2017.06.003.

18.

The Sense of Smell Impacts Metabolic Health and Obesity.

Riera CE, Tsaousidou E, Halloran J, Follett P, Hahn O, Pereira MMA, Ruud LE, Alber J, Tharp K, Anderson CM, Brönneke H, Hampel B, Filho CDM, Stahl A, Brüning JC, Dillin A.

Cell Metab. 2017 Jul 5;26(1):198-211.e5. doi: 10.1016/j.cmet.2017.06.015.

19.

The UPRER: Sensor and Coordinator of Organismal Homeostasis.

Frakes AE, Dillin A.

Mol Cell. 2017 Jun 15;66(6):761-771. doi: 10.1016/j.molcel.2017.05.031. Review.

20.

Neuroendocrine Coordination of Mitochondrial Stress Signaling and Proteostasis.

Berendzen KM, Durieux J, Shao LW, Tian Y, Kim HE, Wolff S, Liu Y, Dillin A.

Cell. 2016 Sep 8;166(6):1553-1563.e10. doi: 10.1016/j.cell.2016.08.042.

21.

Lipid Biosynthesis Coordinates a Mitochondrial-to-Cytosolic Stress Response.

Kim HE, Grant AR, Simic MS, Kohnz RA, Nomura DK, Durieux J, Riera CE, Sanchez M, Kapernick E, Wolff S, Dillin A.

Cell. 2016 Sep 8;166(6):1539-1552.e16. doi: 10.1016/j.cell.2016.08.027.

22.

Mitochondrial UPR: A Double-Edged Sword.

Tian Y, Merkwirth C, Dillin A.

Trends Cell Biol. 2016 Aug;26(8):563-565. doi: 10.1016/j.tcb.2016.06.006. Epub 2016 Jul 6.

PMID:
27394966
23.

A Ribosomal Perspective on Proteostasis and Aging.

Steffen KK, Dillin A.

Cell Metab. 2016 Jun 14;23(6):1004-1012. doi: 10.1016/j.cmet.2016.05.013. Review.

24.

Signaling Networks Determining Life Span.

Riera CE, Merkwirth C, De Magalhaes Filho CD, Dillin A.

Annu Rev Biochem. 2016 Jun 2;85:35-64. doi: 10.1146/annurev-biochem-060815-014451. Review.

PMID:
27294438
25.

Identification and Characterization of Mitochondrial Subtypes in Caenorhabditis elegans via Analysis of Individual Mitochondria by Flow Cytometry.

Daniele JR, Heydari K, Arriaga EA, Dillin A.

Anal Chem. 2016 Jun 21;88(12):6309-16. doi: 10.1021/acs.analchem.6b00542. Epub 2016 Jun 7.

26.

Two Conserved Histone Demethylases Regulate Mitochondrial Stress-Induced Longevity.

Merkwirth C, Jovaisaite V, Durieux J, Matilainen O, Jordan SD, Quiros PM, Steffen KK, Williams EG, Mouchiroud L, Tronnes SU, Murillo V, Wolff SC, Shaw RJ, Auwerx J, Dillin A.

Cell. 2016 May 19;165(5):1209-1223. doi: 10.1016/j.cell.2016.04.012. Epub 2016 Apr 28.

27.

Mitochondrial Stress Induces Chromatin Reorganization to Promote Longevity and UPR(mt).

Tian Y, Garcia G, Bian Q, Steffen KK, Joe L, Wolff S, Meyer BJ, Dillin A.

Cell. 2016 May 19;165(5):1197-1208. doi: 10.1016/j.cell.2016.04.011. Epub 2016 Apr 28.

28.

Emerging Role of Sensory Perception in Aging and Metabolism.

Riera CE, Dillin A.

Trends Endocrinol Metab. 2016 May;27(5):294-303. doi: 10.1016/j.tem.2016.03.007. Epub 2016 Apr 8. Review.

PMID:
27067041
29.

Walking the tightrope: proteostasis and neurodegenerative disease.

Yerbury JJ, Ooi L, Dillin A, Saunders DN, Hatters DM, Beart PM, Cashman NR, Wilson MR, Ecroyd H.

J Neurochem. 2016 May;137(4):489-505. doi: 10.1111/jnc.13575. Epub 2016 Mar 8. Review.

30.

Autophagy-mediated longevity is modulated by lipoprotein biogenesis.

Seah NE, de Magalhaes Filho CD, Petrashen AP, Henderson HR, Laguer J, Gonzalez J, Dillin A, Hansen M, Lapierre LR.

Autophagy. 2016;12(2):261-72. doi: 10.1080/15548627.2015.1127464.

31.

Can aging be 'drugged'?

Riera CE, Dillin A.

Nat Med. 2015 Dec;21(12):1400-5. doi: 10.1038/nm.4005. Review.

PMID:
26646496
32.

Heterotypic Signals from Neural HSF-1 Separate Thermotolerance from Longevity.

Douglas PM, Baird NA, Simic MS, Uhlein S, McCormick MA, Wolff SC, Kennedy BK, Dillin A.

Cell Rep. 2015 Aug 18;12(7):1196-1204. doi: 10.1016/j.celrep.2015.07.026. Epub 2015 Aug 6.

33.

The Deubiquitylase MATH-33 Controls DAF-16 Stability and Function in Metabolism and Longevity.

Heimbucher T, Liu Z, Bossard C, McCloskey R, Carrano AC, Riedel CG, Tanasa B, Klammt C, Fonslow BR, Riera CE, Lillemeier BF, Kemphues K, Yates JR 3rd, O'Shea C, Hunter T, Dillin A.

Cell Metab. 2015 Jul 7;22(1):151-63. doi: 10.1016/j.cmet.2015.06.002.

34.

Tipping the metabolic scales towards increased longevity in mammals.

Riera CE, Dillin A.

Nat Cell Biol. 2015 Mar;17(3):196-203. doi: 10.1038/ncb3107. Review.

PMID:
25720959
35.

Endocrine aspects of organelle stress—cell non-autonomous signaling of mitochondria and the ER.

Schinzel R, Dillin A.

Curr Opin Cell Biol. 2015 Apr;33:102-10. doi: 10.1016/j.ceb.2015.01.006. Epub 2015 Feb 9. Review.

PMID:
25677685
36.

Phosphorylation of LC3 by the Hippo kinases STK3/STK4 is essential for autophagy.

Wilkinson DS, Jariwala JS, Anderson E, Mitra K, Meisenhelder J, Chang JT, Ideker T, Hunter T, Nizet V, Dillin A, Hansen M.

Mol Cell. 2015 Jan 8;57(1):55-68. doi: 10.1016/j.molcel.2014.11.019. Epub 2014 Dec 24.

37.

Meta-analysis of global metabolomic data identifies metabolites associated with life-span extension.

Patti GJ, Tautenhahn R, Johannsen D, Kalisiak E, Ravussin E, Brüning JC, Dillin A, Siuzdak G.

Metabolomics. 2014 Aug 1;10(4):737-743.

38.

The role of protein clearance mechanisms in organismal ageing and age-related diseases.

Vilchez D, Saez I, Dillin A.

Nat Commun. 2014 Dec 8;5:5659. doi: 10.1038/ncomms6659. Review.

PMID:
25482515
39.

Profile of Kazutoshi Mori and Peter Walter, 2014 Lasker Basic Medical Research awardees: The unfolded protein response.

Dillin A.

Proc Natl Acad Sci U S A. 2014 Dec 16;111(50):17696-7. doi: 10.1073/pnas.1419343111. Epub 2014 Dec 5. No abstract available. Erratum in: Proc Natl Acad Sci U S A. 2015 Apr 21;112(16):E2112.

40.

HSF-1-mediated cytoskeletal integrity determines thermotolerance and life span.

Baird NA, Douglas PM, Simic MS, Grant AR, Moresco JJ, Wolff SC, Yates JR 3rd, Manning G, Dillin A.

Science. 2014 Oct 17;346(6207):360-3. doi: 10.1126/science.1253168.

41.

Cell-nonautonomous control of the UPR: mastering energy homeostasis.

Mardones P, Dillin A, Hetz C.

Cell Metab. 2014 Sep 2;20(3):385-7. doi: 10.1016/j.cmet.2014.07.009.

42.

Mass spectrometry-based shotgun proteomic analysis of C. elegans protein complexes.

Fonslow BR, Moresco JJ, Tu PG, Aalto AP, Pasquinelli AE, Dillin AG, Yates JR 3rd.

WormBook. 2014 Jun 24:1-18. doi: 10.1895/wormbook.1.171.1. Review.

43.

TRPV1 pain receptors regulate longevity and metabolism by neuropeptide signaling.

Riera CE, Huising MO, Follett P, Leblanc M, Halloran J, Van Andel R, de Magalhaes Filho CD, Merkwirth C, Dillin A.

Cell. 2014 May 22;157(5):1023-36. doi: 10.1016/j.cell.2014.03.051.

44.
45.

Cell biology: The stressful influence of microbes.

Wolff S, Dillin A.

Nature. 2014 Apr 17;508(7496):328-9. doi: 10.1038/nature13220. Epub 2014 Apr 2. No abstract available.

PMID:
24695220
46.

Differential scales of protein quality control.

Wolff S, Weissman JS, Dillin A.

Cell. 2014 Mar 27;157(1):52-64. doi: 10.1016/j.cell.2014.03.007. Review.

47.

Systemic stress signalling: understanding the cell non-autonomous control of proteostasis.

Taylor RC, Berendzen KM, Dillin A.

Nat Rev Mol Cell Biol. 2014 Mar;15(3):211-7. doi: 10.1038/nrm3752.

48.

The good and the bad of being connected: the integrons of aging.

Dillin A, Gottschling DE, Nyström T.

Curr Opin Cell Biol. 2014 Feb;26:107-12. doi: 10.1016/j.ceb.2013.12.003. Epub 2013 Dec 30. Review.

49.

The disposable soma theory of aging in reverse.

Douglas PM, Dillin A.

Cell Res. 2014 Jan;24(1):7-8. doi: 10.1038/cr.2013.148. Epub 2013 Nov 5.

50.

Nutrition and the biology of human ageing: cognitive decline/food intake and caloric restriction.

le Coutre J, Mattson MP, Dillin A, Friedman J, Bistrian B.

J Nutr Health Aging. 2013;17(8):717-20. doi: 10.1007/s12603-013-0375-2. No abstract available.

PMID:
24097030

Supplemental Content

Loading ...
Support Center