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Items: 47

1.

Radiation-inducible caspase-8 gene therapy for malignant brain tumors.

Tsurushima H, Yuan X, Dillehay LE, Leong KW.

Int J Radiat Oncol Biol Phys. 2008 Jun 1;71(2):517-25. doi: 10.1016/j.ijrobp.2008.02.002. Epub 2008 Apr 11.

PMID:
18407431
2.

Radioresponsive tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) gene therapy for malignant brain tumors.

Tsurushima H, Yuan X, Dillehay LE, Leong KW.

Cancer Gene Ther. 2007 Aug;14(8):706-16. Epub 2007 Jun 1.

PMID:
17541421
3.

ABT-888, an orally active poly(ADP-ribose) polymerase inhibitor that potentiates DNA-damaging agents in preclinical tumor models.

Donawho CK, Luo Y, Luo Y, Penning TD, Bauch JL, Bouska JJ, Bontcheva-Diaz VD, Cox BF, DeWeese TL, Dillehay LE, Ferguson DC, Ghoreishi-Haack NS, Grimm DR, Guan R, Han EK, Holley-Shanks RR, Hristov B, Idler KB, Jarvis K, Johnson EF, Kleinberg LR, Klinghofer V, Lasko LM, Liu X, Marsh KC, McGonigal TP, Meulbroek JA, Olson AM, Palma JP, Rodriguez LE, Shi Y, Stavropoulos JA, Tsurutani AC, Zhu GD, Rosenberg SH, Giranda VL, Frost DJ.

Clin Cancer Res. 2007 May 1;13(9):2728-37.

4.

Radio-responsive gene therapy for malignant glioma cells without the radiosensitive promoter: Caspase-3 gene therapy combined with radiation.

Tsurushima H, Yuan X, Dillehay LE, Leong KW.

Cancer Lett. 2007 Feb 8;246(1-2):318-23. Epub 2006 Apr 27.

PMID:
16644107
5.

Evasion of early cellular response mechanisms following low level radiation-induced DNA damage.

Collis SJ, Schwaninger JM, Ntambi AJ, Keller TW, Nelson WG, Dillehay LE, Deweese TL.

J Biol Chem. 2004 Nov 26;279(48):49624-32. Epub 2004 Sep 17.

6.

Hematopoietic progenitor stem cell homing in mice lethally irradiated with ionizing radiation at differing dose rates.

Collis SJ, Neutzel S, Thompson TL, Swartz MJ, Dillehay LE, Collector MI, Sharkis SJ, DeWeese TL.

Radiat Res. 2004 Jul;162(1):48-55.

PMID:
15222777
7.

IUdR polymers for combined continuous low-dose rate and high-dose rate sensitization of experimental human malignant gliomas.

Yuan X, Dillehay LE, Williams JR, Shastri VR, Williams JA.

Int J Cancer. 2001 Apr 20;96(2):118-25. Erratum in: Int J Cancer 2002 Feb 20;97(6):878.

8.

Synthetic, implantable polymers for IUdR radiosensitization of experimental human malignant glioma.

Yuan X, Dillehay LE, Williams JR, Williams JA.

Cancer Biother Radiopharm. 1999 Jun;14(3):187-202.

PMID:
10850303
9.

Regulation of tumor angiogenesis by p53-induced degradation of hypoxia-inducible factor 1alpha.

Ravi R, Mookerjee B, Bhujwalla ZM, Sutter CH, Artemov D, Zeng Q, Dillehay LE, Madan A, Semenza GL, Bedi A.

Genes Dev. 2000 Jan 1;14(1):34-44.

10.

Predicting cancer rates in astronauts from animal carcinogenesis studies and cellular markers.

Williams JR, Zhang Y, Zhou H, Osman M, Cha D, Kavet R, Cuccinotta F, Dicello JF, Dillehay LE.

Mutat Res. 1999 Dec 6;430(2):255-69.

PMID:
10631340
11.

Retinoic acid-mediated growth inhibition of small cell lung cancer cells is associated with reduced myc and increased p27Kip1 expression.

Weber E, Ravi RK, Knudsen ES, Williams JR, Dillehay LE, Nelkin BD, Kalemkerian GP, Feramisco JR, Mabry M.

Int J Cancer. 1999 Mar 15;80(6):935-43.

12.

Raf-1-induced cell cycle arrest in LNCaP human prostate cancer cells.

Ravi RK, McMahon M, Yangang Z, Williams JR, Dillehay LE, Nelkin BD, Mabry M.

J Cell Biochem. 1999 Mar 15;72(4):458-69.

PMID:
10022606
13.

Protracted exposure radiosensitization of experimental human malignant glioma.

Williams JA, Williams JR, Yuan X, Dillehay LE.

Radiat Oncol Investig. 1998;6(6):255-63.

PMID:
9885941
14.
15.

Synthetic, implantable polymers for local delivery of IUdR to experimental human malignant glioma.

Williams JA, Yuan X, Dillehay LE, Shastri VR, Brem H, Williams JR.

Int J Radiat Oncol Biol Phys. 1998 Oct 1;42(3):631-9.

PMID:
9806525
16.

Sensitivity of human prostatic carcinoma cell lines to low dose rate radiation exposure.

DeWeese TL, Shipman JM, Dillehay LE, Nelson WG.

J Urol. 1998 Feb;159(2):591-8.

PMID:
9649298
17.

Effect of interstitial and/or systemic delivery of tirapazamine on the radiosensitivity of human glioblastoma multiforme in nude mice.

Cardinale RM, Dillehay LE, Williams JA, Tabassi K, Brem H, Lee DJ.

Radiat Oncol Investig. 1998;6(2):63-70.

PMID:
9572682
18.

Activated Raf-1 causes growth arrest in human small cell lung cancer cells.

Ravi RK, Weber E, McMahon M, Williams JR, Baylin S, Mal A, Harter ML, Dillehay LE, Claudio PP, Giordano A, Nelkin BD, Mabry M.

J Clin Invest. 1998 Jan 1;101(1):153-9.

19.

Implantable biodegradable polymers for IUdR radiosensitization of experimental human malignant glioma.

Williams JA, Dillehay LE, Tabassi K, Sipos E, Fahlman C, Brem H.

J Neurooncol. 1997 May;32(3):181-92.

PMID:
9049879
20.

Decreasing resistance during fast infusion of a subcutaneous tumor.

Dillehay LE.

Anticancer Res. 1997 Jan-Feb;17(1A):461-6.

PMID:
9066695
21.

Human papillomavirus E6 and E7 oncoproteins alter cell cycle progression but not radiosensitivity of carcinoma cells treated with low-dose-rate radiation.

DeWeese TL, Walsh JC, Dillehay LE, Kessis TD, Hedrick L, Cho KR, Nelson WG.

Int J Radiat Oncol Biol Phys. 1997 Jan 1;37(1):145-54.

PMID:
9054890
22.

Prediction of tumor response to experimental radioimmunotherapy with 90Y in nude mice.

Dillehay LE, Mayer R, Zhang YG, Shao Y, Song SY, Mackensen DG, Williams JR.

Int J Radiat Oncol Biol Phys. 1995 Sep 30;33(2):417-27.

PMID:
7673029
23.

Direct measurement of intratumor dose-rate distributions in experimental xenografts treated with 90Y-labeled radioimmunotherapy.

Mayer R, Dillehay LE, Shao Y, Zhang YG, Song S, Bartholomew RM, Mackenson DG, Williams JR.

Int J Radiat Oncol Biol Phys. 1995 Apr 30;32(1):147-57.

PMID:
7721611
24.

The effect of polyamine depletion on the cytotoxic response to PUVA, gamma rays and UVC in V79 cells in vitro.

Williams JR, Casero RA, Dillehay LE.

Biochem Biophys Res Commun. 1994 May 30;201(1):1-7.

PMID:
8198560
25.

Use of bremsstrahlung radiation to monitor Y-90 tumor and whole body activities during experimental radioimmunotherapy in mice.

Dillehay LE, Mayer R, Zhang YG, Song SY, Shao Y, Mackensen DG, Williams JR.

Cancer. 1994 Feb 1;73(3 Suppl):945-50.

PMID:
8306283
26.

A new method for determining dose rate distribution from radioimmuno-therapy using radiochromic media.

Mayer R, Dillehay LE, Shao Y, Song S, Zhang YG, Bartholomew RM, Williams JR.

Int J Radiat Oncol Biol Phys. 1994 Jan 15;28(2):505-13.

PMID:
8276668
27.

Quantitative comparison of radiolabeled antibody therapy and external beam radiotherapy in the treatment of human glioma xenografts.

Williams JA, Edwards JA, Dillehay LE.

Int J Radiat Oncol Biol Phys. 1992;24(1):111-7.

PMID:
1512146
28.

Sensitization processes in human tumor cells during protracted irradiation: possible exploitation in the clinic.

Williams JR, Zhang YG, Dillehay LE.

Int J Radiat Oncol Biol Phys. 1992;24(4):699-704.

PMID:
1429094
29.

Response of glioblastoma cell lines to low dose rate irradiation.

Marin LA, Smith CE, Langston MY, Quashie D, Dillehay LE.

Int J Radiat Oncol Biol Phys. 1991 Jul;21(2):397-402.

PMID:
2061116
31.
32.

Targeting and therapy of human glioma xenografts in vivo using radiolabeled antibodies.

Williams JA, Edwards JA, Wessels BW, Dillehay LE, Wanek PM, Poggenburg JK, Wharam MD, Order SE, Klein JL.

Int J Radiat Oncol Biol Phys. 1990 Sep;19(3):633-42.

PMID:
2170301
33.

Radiobiology of dose-rate patterns achievable in radioimmunoglobulin therapy.

Dillehay LE, Williams JR.

Front Radiat Ther Oncol. 1990;24:96-103; discussion 121-2. Review. No abstract available.

PMID:
2160409
34.

Yttrium-90 and iodine-131 radioimmunoglobulin therapy of an experimental human hepatoma.

Klein JL, Nguyen TH, Laroque P, Kopher KA, Williams JR, Wessels BW, Dillehay LE, Frincke J, Order SE, Leichner PK.

Cancer Res. 1989 Nov 15;49(22):6383-9.

35.

DNA topoisomerases and models of sister-chromatid exchange.

Dillehay LE, Jacobson-Kram D, Williams JR.

Mutat Res. 1989 Nov;215(1):15-23.

PMID:
2554135
36.

Heritable hypersensitivity to induced mutagenesis in the progeny of cell populations exposed to UVC (254 nm).

D'Arpa P, Dillehay LE, Opishinski JW, Jacobson-Kram D, Williams JR.

Radiat Res. 1989 Jan;117(1):163-9.

PMID:
2521533
37.
38.

Low-dose-rate radiation sensitivity of a human hepatoma cell line.

Dillehay LE, Cathers LE.

NCI Monogr. 1987;(3):43-6.

PMID:
3029603
39.
40.
41.

Enhanced susceptibility to HPD-sensitized phototoxicity and correlated resistance to trypsin detachment in SV40 transformed IMR-90 cells.

Denstman SC, Dillehay LE, Williams JR.

Photochem Photobiol. 1986 Feb;43(2):145-7. No abstract available.

PMID:
3010344
42.

DNA-strand breaks associated with halogenated pyrimidine incorporation.

Dillehay LE, Thompson LH, Carrano AV.

Mutat Res. 1984 Mar-Apr;131(3-4):129-36.

PMID:
6717468
43.

Cytogenetic characterization of the Chinese hamster ovary mutant EM9.

Dillehay LE, Thompson LH, Carrano AV.

Basic Life Sci. 1984;29 Pt A:103-7. No abstract available.

PMID:
6532414
44.

The relationship between sister-chromatid exchange and perturbations in DNA replication in mutant EM9 and normal CHO cells.

Dillehay LE, Thompson LH, Minkler JL, Carrano AV.

Mutat Res. 1983 May;109(2):283-96.

PMID:
6843572
45.

Hypersensitivity to mutation and sister-chromatid-exchange induction in CHO cell mutants defective in incising DNA containing UV lesions.

Thompson LH, Brookman KW, Dillehay LE, Mooney CL, Carrano AV.

Somatic Cell Genet. 1982 Nov;8(6):759-73.

PMID:
7163954
46.

A CHO-cell strain having hypersensitivity to mutagens, a defect in DNA strand-break repair, and an extraordinary baseline frequency of sister-chromatid exchange.

Thompson LH, Brookman KW, Dillehay LE, Carrano AV, Mazrimas JA, Mooney CL, Minkler JL.

Mutat Res. 1982 Aug;95(2-3):427-40.

PMID:
6889677
47.

Role of DNA repair in mutagenesis of Chinese hamster ovary cells by 7-bromomethylbenz[a]anthracene.

Thompson LH, Brookman KW, Carrano AV, Dillehay LE.

Proc Natl Acad Sci U S A. 1982 Jan;79(2):534-8.

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