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Items: 47


Erratum for Sehrawat et al., "Cancer-Associated Eukaryotic Translation Initiation Factor 1A Mutants Impair Rps3 and Rps10 Binding and Enhance Scanning of Cell Cycle Genes".

Sehrawat U, Koning F, Ashkenazi S, Stelzer G, Leshkowitz D, Dikstein R.

Mol Cell Biol. 2019 Mar 1;39(6). pii: e00049-19. doi: 10.1128/MCB.00049-19. Print 2019 Mar 15. No abstract available.


Cancer-Associated Eukaryotic Translation Initiation Factor 1A Mutants Impair Rps3 and Rps10 Binding and Enhance Scanning of Cell Cycle Genes.

Sehrawat U, Koning F, Ashkenazi S, Stelzer G, Leshkowitz D, Dikstein R.

Mol Cell Biol. 2019 Jan 16;39(3). pii: e00441-18. doi: 10.1128/MCB.00441-18. Print 2019 Feb 1. Erratum in: Mol Cell Biol. 2019 Mar 1;39(6):.


Dynamic Interaction of Eukaryotic Initiation Factor 4G1 (eIF4G1) with eIF4E and eIF1 Underlies Scanning-Dependent and -Independent Translation.

Haimov O, Sehrawat U, Tamarkin-Ben Harush A, Bahat A, Uzonyi A, Will A, Hiraishi H, Asano K, Dikstein R.

Mol Cell Biol. 2018 Aug 28;38(18). pii: e00139-18. doi: 10.1128/MCB.00139-18. Print 2018 Sep 15.


Efficient and Accurate Translation Initiation Directed by TISU Involves RPS3 and RPS10e Binding and Differential Eukaryotic Initiation Factor 1A Regulation.

Haimov O, Sinvani H, Martin F, Ulitsky I, Emmanuel R, Tamarkin-Ben-Harush A, Vardy A, Dikstein R.

Mol Cell Biol. 2017 Jul 14;37(15). pii: e00150-17. doi: 10.1128/MCB.00150-17. Print 2017 Aug 1.


Effective cell-free drug screening protocol for protein-protein interaction.

Ashkenazi S, Plotnikov A, Bahat A, Dikstein R.

Anal Biochem. 2017 Sep 1;532:53-59. doi: 10.1016/j.ab.2017.05.030. Epub 2017 Jun 1.


Cap-proximal nucleotides via differential eIF4E binding and alternative promoter usage mediate translational response to energy stress.

Tamarkin-Ben-Harush A, Vasseur JJ, Debart F, Ulitsky I, Dikstein R.

Elife. 2017 Feb 8;6. pii: e21907. doi: 10.7554/eLife.21907.


The elongation factor Spt5 facilitates transcription initiation for rapid induction of inflammatory-response genes.

Diamant G, Bahat A, Dikstein R.

Nat Commun. 2016 May 16;7:11547. doi: 10.1038/ncomms11547.


Analysis of Subcellular RNA Fractions Revealed a Transcription-Independent Effect of Tumor Necrosis Factor Alpha on Splicing, Mediated by Spt5.

Diamant G, Eisenbaum T, Leshkowitz D, Dikstein R.

Mol Cell Biol. 2016 Apr 15;36(9):1342-53. doi: 10.1128/MCB.01117-15. Print 2016 May.


A Novel Allosteric Mechanism of NF-κB Dimerization and DNA Binding Targeted by an Anti-Inflammatory Drug.

Ashkenazi S, Plotnikov A, Bahat A, Ben-Zeev E, Warszawski S, Dikstein R.

Mol Cell Biol. 2016 Mar 31;36(8):1237-47. doi: 10.1128/MCB.00895-15. Print 2016 Apr.


DTIE, a novel core promoter element that directs start site selection in TATA-less genes.

Marbach-Bar N, Bahat A, Ashkenazi S, Golan-Mashiach M, Haimov O, Wu SY, Chiang CM, Puzio-Kuter A, Hirshfield KM, Levine AJ, Dikstein R.

Nucleic Acids Res. 2016 Feb 18;44(3):1080-94. doi: 10.1093/nar/gkv1032. Epub 2015 Oct 12.


Cap-dependent, scanning-free translation initiation mechanisms.

Haimov O, Sinvani H, Dikstein R.

Biochim Biophys Acta. 2015 Nov;1849(11):1313-8. doi: 10.1016/j.bbagrm.2015.09.006. Epub 2015 Sep 14. Review.


Translational tolerance of mitochondrial genes to metabolic energy stress involves TISU and eIF1-eIF4GI cooperation in start codon selection.

Sinvani H, Haimov O, Svitkin Y, Sonenberg N, Tamarkin-Ben-Harush A, Viollet B, Dikstein R.

Cell Metab. 2015 Mar 3;21(3):479-92. doi: 10.1016/j.cmet.2015.02.010.


Co-occurrence of transcription and translation gene regulatory features underlies coordinated mRNA and protein synthesis.

Tamarkin-Ben-Harush A, Schechtman E, Dikstein R.

BMC Genomics. 2014 Aug 19;15:688. doi: 10.1186/1471-2164-15-688.


Disparity between microRNA levels and promoter strength is associated with initiation rate and Pol II pausing.

Marbach-Bar N, Ben-Noon A, Ashkenazi S, Tamarkin-Ben Harush A, Avnit-Sagi T, Walker MD, Dikstein R.

Nat Commun. 2013;4:2118. doi: 10.1038/ncomms3118.


Transcriptional control by NF-κB: elongation in focus.

Diamant G, Dikstein R.

Biochim Biophys Acta. 2013 Sep;1829(9):937-45. doi: 10.1016/j.bbagrm.2013.04.007. Epub 2013 Apr 25. Review.


TAF4b and TAF4 differentially regulate mouse embryonic stem cells maintenance and proliferation.

Bahat A, Kedmi R, Gazit K, Richardo-Lax I, Ainbinder E, Dikstein R.

Genes Cells. 2013 Mar;18(3):225-37. doi: 10.1111/gtc.12030. Epub 2013 Jan 27.


DSIF restricts NF-κB signaling by coordinating elongation with mRNA processing of negative feedback genes.

Diamant G, Amir-Zilberstein L, Yamaguchi Y, Handa H, Dikstein R.

Cell Rep. 2012 Oct 25;2(4):722-31. doi: 10.1016/j.celrep.2012.08.041. Epub 2012 Oct 4.


The unexpected traits associated with core promoter elements.

Dikstein R.

Transcription. 2011 Sep-Oct;2(5):201-6. doi: 10.4161/trns.2.5.17271. Review.


Identification of CTCF as a master regulator of the clustered protocadherin genes.

Golan-Mashiach M, Grunspan M, Emmanuel R, Gibbs-Bar L, Dikstein R, Shapiro E.

Nucleic Acids Res. 2012 Apr;40(8):3378-91. doi: 10.1093/nar/gkr1260. Epub 2011 Dec 30.


Transcription and translation in a package deal: the TISU paradigm.

Dikstein R.

Gene. 2012 Jan 1;491(1):1-4. doi: 10.1016/j.gene.2011.09.013. Epub 2011 Oct 1. Review.


Unique translation initiation of mRNAs-containing TISU element.

Elfakess R, Sinvani H, Haimov O, Svitkin Y, Sonenberg N, Dikstein R.

Nucleic Acids Res. 2011 Sep 1;39(17):7598-609. doi: 10.1093/nar/gkr484. Epub 2011 Jun 25.


miR-22 forms a regulatory loop in PTEN/AKT pathway and modulates signaling kinetics.

Bar N, Dikstein R.

PLoS One. 2010 May 27;5(5):e10859. doi: 10.1371/journal.pone.0010859.


TAF4b and Jun/activating protein-1 collaborate to regulate the expression of integrin alpha6 and cancer cell migration properties.

Kalogeropoulou M, Voulgari A, Kostourou V, Sandaltzopoulos R, Dikstein R, Davidson I, Tora L, Pintzas A.

Mol Cancer Res. 2010 Apr;8(4):554-68. doi: 10.1158/1541-7786.MCR-09-0159. Epub 2010 Mar 30.


TAF4/4b x TAF12 displays a unique mode of DNA binding and is required for core promoter function of a subset of genes.

Gazit K, Moshonov S, Elfakess R, Sharon M, Mengus G, Davidson I, Dikstein R.

J Biol Chem. 2009 Sep 25;284(39):26286-96. doi: 10.1074/jbc.M109.011486. Epub 2009 Jul 27.


Characterization of sINR, a strict version of the Initiator core promoter element.

Yarden G, Elfakess R, Gazit K, Dikstein R.

Nucleic Acids Res. 2009 Jul;37(13):4234-46. doi: 10.1093/nar/gkp315. Epub 2009 May 13.


A translation initiation element specific to mRNAs with very short 5'UTR that also regulates transcription.

Elfakess R, Dikstein R.

PLoS One. 2008 Aug 28;3(8):e3094. doi: 10.1371/journal.pone.0003094.


Links between core promoter and basic gene features influence gene expression.

Moshonov S, Elfakess R, Golan-Mashiach M, Sinvani H, Dikstein R.

BMC Genomics. 2008 Feb 25;9:92. doi: 10.1186/1471-2164-9-92.


Interplay between E-box and NF-kappaB in regulation of A20 gene by DRB sensitivity-inducing factor (DSIF).

Amir-Zilberstein L, Dikstein R.

J Biol Chem. 2008 Jan 18;283(3):1317-23. Epub 2007 Oct 25.


CD74 induces TAp63 expression leading to B-cell survival.

Lantner F, Starlets D, Gore Y, Flaishon L, Yamit-Hezi A, Dikstein R, Leng L, Bucala R, Machluf Y, Oren M, Shachar I.

Blood. 2007 Dec 15;110(13):4303-11. Epub 2007 Sep 10.


Differential regulation of NF-kappaB by elongation factors is determined by core promoter type.

Amir-Zilberstein L, Ainbinder E, Toube L, Yamaguchi Y, Handa H, Dikstein R.

Mol Cell Biol. 2007 Jul;27(14):5246-59. Epub 2007 May 14.


Core promoter binding by histone-like TAF complexes.

Shao H, Revach M, Moshonov S, Tzuman Y, Gazit K, Albeck S, Unger T, Dikstein R.

Mol Cell Biol. 2005 Jan;25(1):206-19.


Elongation inhibition by DRB sensitivity-inducing factor is regulated by the A20 promoter via a novel negative element and NF-kappaB.

Ainbinder E, Amir-Zilberstein L, Yamaguchi Y, Handa H, Dikstein R.

Mol Cell Biol. 2004 Mar;24(6):2444-54.


Mechanism of rapid transcriptional induction of tumor necrosis factor alpha-responsive genes by NF-kappaB.

Ainbinder E, Revach M, Wolstein O, Moshonov S, Diamant N, Dikstein R.

Mol Cell Biol. 2002 Sep;22(18):6354-62.


NF-kappa B DNA-binding activity in embryos responding to a teratogen, cyclophosphamide.

Torchinsky A, Lishanski L, Wolstein O, Shepshelovich J, Orenstein H, Savion S, Zaslavsky Z, Carp H, Brill A, Dikstein R, Toder V, Fein A.

BMC Dev Biol. 2002;2:2. Epub 2002 Feb 5.


Enhanced apoptosis of B and T lymphocytes in TAFII105 dominant-negative transgenic mice is linked to nuclear factor-kappa B.

Silkov A, Wolstein O, Shachar I, Dikstein R.

J Biol Chem. 2002 May 17;277(20):17821-9. Epub 2002 Feb 20.


A composite nuclear export signal in the TBP-associated factor TAFII105.

Rashevsky-Finkel A, Silkov A, Dikstein R.

J Biol Chem. 2001 Nov 30;276(48):44963-9. Epub 2001 Sep 20.


Invariant chain induces B cell maturation by activating a TAF(II)105-NF-kappaB-dependent transcription program.

Matza D, Wolstein O, Dikstein R, Shachar I.

J Biol Chem. 2001 Jul 20;276(29):27203-6. Epub 2001 May 22.


Interaction of TAFII105 with selected p65/RelA dimers is associated with activation of subset of NF-kappa B genes.

Yamit-Hezi A, Nir S, Wolstein O, Dikstein R.

J Biol Chem. 2000 Jun 16;275(24):18180-7.


Specific interaction of TAFII105 with OCA-B is involved in activation of octamer-dependent transcription.

Wolstein O, Silkov A, Revach M, Dikstein R.

J Biol Chem. 2000 Jun 2;275(22):16459-65.


TAFII105 mediates activation of anti-apoptotic genes by NF-kappaB.

Yamit-Hezi A, Dikstein R.

EMBO J. 1998 Sep 1;17(17):5161-9.


Human TAFII 105 is a cell type-specific TFIID subunit related to hTAFII130.

Dikstein R, Zhou S, Tjian R.

Cell. 1996 Oct 4;87(1):137-46.


p140/c-Abl that binds DNA is preferentially phosphorylated at tyrosine residues.

Dikstein R, Agami R, Heffetz D, Shaul Y.

Proc Natl Acad Sci U S A. 1996 Mar 19;93(6):2387-91.


c-abl has a sequence-specific enhancer binding activity.

Dikstein R, Heffetz D, Ben-Neriah Y, Shaul Y.

Cell. 1992 May 29;69(5):751-7.


Functional organization of the hepatitis B virus enhancer.

Dikstein R, Faktor O, Ben-Levy R, Shaul Y.

Mol Cell Biol. 1990 Jul;10(7):3683-9.


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