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Items: 44


The Euvichol story - Development and licensure of a safe, effective and affordable oral cholera vaccine through global public private partnerships.

Odevall L, Hong D, Digilio L, Sahastrabuddhe S, Mogasale V, Baik Y, Choi S, Kim JH, Lynch J.

Vaccine. 2018 Oct 29;36(45):6606-6614. doi: 10.1016/j.vaccine.2018.09.026. Epub 2018 Oct 9. Review.


A dominant dendrite phenotype caused by the disease-associated G253D mutation in doublecortin (DCX) is not due to its endocytosis defect.

Yap CC, Digilio L, Kruczek K, Roszkowska M, Fu XQ, Liu JS, Winckler B.

J Biol Chem. 2018 Dec 7;293(49):18890-18902. doi: 10.1074/jbc.RA118.004462. Epub 2018 Oct 5.


Degradation of dendritic cargos requires Rab7-dependent transport to somatic lysosomes.

Yap CC, Digilio L, McMahon LP, Garcia ADR, Winckler B.

J Cell Biol. 2018 Sep 3;217(9):3141-3159. doi: 10.1083/jcb.201711039. Epub 2018 Jun 15.


A randomized, observer-blinded, equivalence trial comparing two variations of Euvichol®, a bivalent killed whole-cell oral cholera vaccine, in healthy adults and children in the Philippines.

Russo P, Ligsay AD, Olveda R, Choi SK, Kim DR, Park JY, Park JY, Syed KA, Dey A, Kim YH, Lee SH, Kim J, Chon Y, Digilio L, Kim CW, Excler JL.

Vaccine. 2018 Jul 5;36(29):4317-4324. doi: 10.1016/j.vaccine.2018.05.102. Epub 2018 Jun 9.


Use of oral cholera vaccine as a vaccine probe to define the geographical dimensions of person-to-person transmission of cholera.

Ali M, Kim DR, Kanungo S, Sur D, Manna B, Digilio L, Dutta S, Marks F, Bhattacharya SK, Clemens J.

Int J Infect Dis. 2018 Jan;66:90-95. doi: 10.1016/j.ijid.2017.11.020. Epub 2017 Nov 22.


The endosomal neuronal proteins Nsg1/NEEP21 and Nsg2/P19 are itinerant, not resident proteins of dendritic endosomes.

Yap CC, Digilio L, McMahon L, Winckler B.

Sci Rep. 2017 Sep 5;7(1):10481. doi: 10.1038/s41598-017-07667-x.


Protection against cholera from killed whole-cell oral cholera vaccines: a systematic review and meta-analysis.

Bi Q, Ferreras E, Pezzoli L, Legros D, Ivers LC, Date K, Qadri F, Digilio L, Sack DA, Ali M, Lessler J, Luquero FJ, Azman AS; Oral Cholera Vaccine Working Group of The Global Task Force on Cholera Control.

Lancet Infect Dis. 2017 Oct;17(10):1080-1088. doi: 10.1016/S1473-3099(17)30359-6. Epub 2017 Jul 17. Review.


Lessons learnt from 12 oral cholera vaccine campaigns in resource-poor settings.

Hsiao A, Desai SN, Mogasale V, Excler JL, Digilio L.

Bull World Health Organ. 2017 Apr 1;95(4):303-312. doi: 10.2471/BLT.16.175166. Epub 2017 Feb 21.


Different Doublecortin (DCX) Patient Alleles Show Distinct Phenotypes in Cultured Neurons: EVIDENCE FOR DIVERGENT LOSS-OF-FUNCTION AND "OFF-PATHWAY" CELLULAR MECHANISMS.

Yap CC, Digilio L, McMahon L, Roszkowska M, Bott CJ, Kruczek K, Winckler B.

J Biol Chem. 2016 Dec 23;291(52):26613-26626. doi: 10.1074/jbc.M116.760777. Epub 2016 Oct 31.


Potential for Controlling Cholera Using a Ring Vaccination Strategy: Re-analysis of Data from a Cluster-Randomized Clinical Trial.

Ali M, Debes AK, Luquero FJ, Kim DR, Park JY, Digilio L, Manna B, Kanungo S, Dutta S, Sur D, Bhattacharya SK, Sack DA.

PLoS Med. 2016 Sep 13;13(9):e1002120. doi: 10.1371/journal.pmed.1002120. eCollection 2016 Sep.


Comparison of immune responses to a killed bivalent whole cell oral cholera vaccine between endemic and less endemic settings.

Desai SN, Akalu Z, Teferi M, Manna B, Teshome S, Park JY, Yang JS, Kim DR, Kanungo S, Digilio L.

Trop Med Int Health. 2016 Feb;21(2):194-201. doi: 10.1111/tmi.12641. Epub 2015 Dec 18.


Doublecortin (DCX) mediates endocytosis of neurofascin independently of microtubule binding.

Yap CC, Vakulenko M, Kruczek K, Motamedi B, Digilio L, Liu JS, Winckler B.

J Neurosci. 2012 May 30;32(22):7439-53. doi: 10.1523/JNEUROSCI.5318-11.2012.


Oocyte specific oolemmal SAS1B involved in sperm binding through intra-acrosomal SLLP1 during fertilization.

Sachdev M, Mandal A, Mulders S, Digilio LC, Panneerdoss S, Suryavathi V, Pires E, Klotz KL, Hermens L, Herrero MB, Flickinger CJ, van Duin M, Herr JC.

Dev Biol. 2012 Mar 1;363(1):40-51. doi: 10.1016/j.ydbio.2011.12.021. Epub 2011 Dec 20.


CABYR binds to AKAP3 and Ropporin in the human sperm fibrous sheath.

Li YF, He W, Mandal A, Kim YH, Digilio L, Klotz K, Flickinger CJ, Herr JC, Herr JC.

Asian J Androl. 2011 Mar;13(2):266-74. doi: 10.1038/aja.2010.149. Epub 2011 Jan 17.


CABYR isoforms expressed in late steps of spermiogenesis bind with AKAPs and ropporin in mouse sperm fibrous sheath.

Li YF, He W, Kim YH, Mandal A, Digilio L, Klotz K, Flickinger CJ, Herr JC.

Reprod Biol Endocrinol. 2010 Aug 23;8:101. doi: 10.1186/1477-7827-8-101.


Targeted deletion of Tssk1 and 2 causes male infertility due to haploinsufficiency.

Xu B, Hao Z, Jha KN, Zhang Z, Urekar C, Digilio L, Pulido S, Strauss JF 3rd, Flickinger CJ, Herr JC.

Dev Biol. 2008 Jul 15;319(2):211-22. doi: 10.1016/j.ydbio.2008.03.047. Epub 2008 Apr 23.


TSKS concentrates in spermatid centrioles during flagellogenesis.

Xu B, Hao Z, Jha KN, Zhang Z, Urekar C, Digilio L, Pulido S, Strauss JF 3rd, Flickinger CJ, Herr JC.

Dev Biol. 2008 Jul 15;319(2):201-10. doi: 10.1016/j.ydbio.2008.03.043. Epub 2008 Apr 11.


Biochemical and structural characterization of apolipoprotein A-I binding protein, a novel phosphoprotein with a potential role in sperm capacitation.

Jha KN, Shumilin IA, Digilio LC, Chertihin O, Zheng H, Schmitz G, Visconti PE, Flickinger CJ, Minor W, Herr JC.

Endocrinology. 2008 May;149(5):2108-20. doi: 10.1210/en.2007-0582. Epub 2008 Jan 17.


Distribution of RNA binding protein MOEP19 in the oocyte cortex and early embryo indicates pre-patterning related to blastomere polarity and trophectoderm specification.

Herr JC, Chertihin O, Digilio L, Jha KN, Vemuganti S, Flickinger CJ.

Dev Biol. 2008 Feb 15;314(2):300-16. doi: 10.1016/j.ydbio.2007.11.027. Epub 2007 Dec 4.


Equatorial segment protein (ESP) is a human alloantigen involved in sperm-egg binding and fusion.

Wolkowicz MJ, Digilio L, Klotz K, Shetty J, Flickinger CJ, Herr JC.

J Androl. 2008 May-Jun;29(3):272-82. Epub 2007 Oct 31.


FSCB, a novel protein kinase A-phosphorylated calcium-binding protein, is a CABYR-binding partner involved in late steps of fibrous sheath biogenesis.

Li YF, He W, Jha KN, Klotz K, Kim YH, Mandal A, Pulido S, Digilio L, Flickinger CJ, Herr JC.

J Biol Chem. 2007 Nov 23;282(47):34104-19. Epub 2007 Sep 12.


Immunogenicity of a multi-component recombinant human acrosomal protein vaccine in female Macaca fascicularis.

Kurth BE, Digilio L, Snow P, Bush LA, Wolkowicz M, Shetty J, Mandal A, Hao Z, Reddi PP, Flickinger CJ, Herr JC.

J Reprod Immunol. 2008 Apr;77(2):126-41. Epub 2007 Jul 23.


Validation of a testis specific serine/threonine kinase [TSSK] family and the substrate of TSSK1 & 2, TSKS, as contraceptive targets.

Xu B, Hao Z, Jha KN, Digilio L, Urekar C, Kim YH, Pulido S, Flickinger CJ, Herr JC.

Soc Reprod Fertil Suppl. 2007;63:87-101. Review.


Safety and immunogenicity of a measles, mumps, rubella and varicella vaccine given with combined Haemophilus influenzae type b conjugate/hepatitis B vaccines and combined diphtheria-tetanus-acellular pertussis vaccines.

Shinefield H, Black S, Thear M, Coury D, Reisinger K, Rothstein E, Xu J, Hartzel J, Evans B, Digilio L, Schödel F, Brown ML, Kuter B; 013 Study Group for ProQuad.

Pediatr Infect Dis J. 2006 Apr;25(4):287-92.


Evaluation of a quadrivalent measles, mumps, rubella and varicella vaccine in healthy children.

Shinefield H, Black S, Digilio L, Reisinger K, Blatter M, Gress JO, Brown ML, Eves KA, Klopfer SO, Schödel F, Kuter BJ.

Pediatr Infect Dis J. 2005 Aug;24(8):665-9.


Mouse SLLP1, a sperm lysozyme-like protein involved in sperm-egg binding and fertilization.

Herrero MB, Mandal A, Digilio LC, Coonrod SA, Maier B, Herr JC.

Dev Biol. 2005 Aug 1;284(1):126-42.


Dynamic alterations of specific histone modifications during early murine development.

Sarmento OF, Digilio LC, Wang Y, Perlin J, Herr JC, Allis CD, Coonrod SA.

J Cell Sci. 2004 Sep 1;117(Pt 19):4449-59. Epub 2004 Aug 17.


Oocyte proteomics: localisation of mouse zona pellucida protein 3 to the plasma membrane of ovulated mouse eggs.

Coonrod SA, Calvert ME, Reddi PP, Kasper EN, Digilio LC, Herr JC.

Reprod Fertil Dev. 2004;16(1-2):69-78.


SAMP14, a novel, acrosomal membrane-associated, glycosylphosphatidylinositol-anchored member of the Ly-6/urokinase-type plasminogen activator receptor superfamily with a role in sperm-egg interaction.

Shetty J, Wolkowicz MJ, Digilio LC, Klotz KL, Jayes FL, Diekman AB, Westbrook VA, Farris EM, Hao Z, Coonrod SA, Flickinger CJ, Herr JC.

J Biol Chem. 2003 Aug 15;278(33):30506-15. Epub 2003 Jun 4.


Parallel evolution of CCR5-null phenotypes in humans and in a natural host of simian immunodeficiency virus.

Palacios E, Digilio L, McClure HM, Chen Z, Marx PA, Goldsmith MA, Grant RM.

Curr Biol. 1998 Jul 30-Aug 13;8(16):943-6.


Sexual transmission of an HIV-1 variant resistant to multiple reverse-transcriptase and protease inhibitors.

Hecht FM, Grant RM, Petropoulos CJ, Dillon B, Chesney MA, Tian H, Hellmann NS, Bandrapalli NI, Digilio L, Branson B, Kahn JO.

N Engl J Med. 1998 Jul 30;339(5):307-11. No abstract available.


The simian T-lymphotropic/leukemia virus from Pan paniscus belongs to the type 2 family and infects Asian macaques.

Digilio L, Giri A, Cho N, Slattery J, Markham P, Franchini G.

J Virol. 1997 May;71(5):3684-92.


Biochemical response to interferon of chronic hepatitis in drug-addict patients infected with human immunodeficiency virus.

Nardiello S, Pizzella T, Gargiulo M, Gramenzi A, Digilio L, Di Ottavio L, Galanti B.

Infez Med. 1997 Mar;5(1):29-33.


Multiple extracellular elements of CCR5 and HIV-1 entry: dissociation from response to chemokines.

Atchison RE, Gosling J, Monteclaro FS, Franci C, Digilio L, Charo IF, Goldsmith MA.

Science. 1996 Dec 13;274(5294):1924-6.


The natural history and evolution of human and simian T cell leukemia/lymphotropic viruses.

Dekaban GA, Digilio L, Franchini G.

Curr Opin Genet Dev. 1995 Dec;5(6):807-13. Review.


Cytomegalovirus as a co-factor of disease progression in human immunodeficiency virus type 1 infection.

Nardiello S, Digilio L, Pizzella T, Galanti B.

Int J Clin Lab Res. 1994;24(2):86-9. Review.


Relation of changes in hepatitis B virus replication markers to the outcome of interferon treatment in patients with chronic hepatitis.

Nardiello S, Gargiulo M, Pizzella T, Digilio L, Di Ottavio L, Galanti B.

J Chemother. 1992 Apr;4(2):95-8.


Effect of prednisone priming followed by alfa-interferon in treatment of children with chronic hepatitis B: an interim analysis of a controlled trial.

Utili R, Sagnelli E, Giusti G, Ruggiero G, Piccinino F, Galanti B, Adinolfi LE, Aprea L, Cesaro G, Digilio L, et al.

Arch Virol Suppl. 1992;4:277-80.


Prolonged treatment of children with chronic hepatitis B with recombinant alpha 2a-interferon: a controlled, randomized study.

Utili R, Sagnelli E, Galanti B, Aprea L, Cesaro G, Digilio L, Filippini P, Felaco FM, Gaeta GB, Marrone A, et al.

Am J Gastroenterol. 1991 Mar;86(3):327-30.


Subclass characterization of IgG anti-S.typhi lipopolysaccharide antibodies with commercial monoclonal antibodies.

Nardiello S, Digilio L, Leva E, Pizzella T, Galanti B.

Boll Ist Sieroter Milan. 1989;68(3):234-40.


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