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Influence of Rainfall on Leptospira Infection and Disease in a Tropical Urban Setting, Brazil.

Hacker KP, Sacramento GA, Cruz JS, de Oliveira D, Nery N Jr, Lindow JC, Carvalho M, Hagan J, Diggle PJ, Begon M, Reis MG, Wunder EA Jr, Ko AI, Costa F.

Emerg Infect Dis. 2020 Feb;26(2):311-314. doi: 10.3201/eid2602.190102.


Design and Analysis of Elimination Surveys for Neglected Tropical Diseases.

Fronterre C, Amoah B, Giorgi E, Stanton MC, Diggle PJ.

J Infect Dis. 2020 Jan 13. pii: jiz554. doi: 10.1093/infdis/jiz554. [Epub ahead of print]


Childhood malaria case incidence in Malawi between 2004 and 2017: spatio-temporal modelling of climate and non-climate factors.

Chirombo J, Ceccato P, Lowe R, Terlouw DJ, Thomson MC, Gumbo A, Diggle PJ, Read JM.

Malar J. 2020 Jan 6;19(1):5. doi: 10.1186/s12936-019-3097-z.


Mapping species richness using opportunistic samples: a case study on ground-floor bryophyte species richness in the Belgian province of Limburg.

Neyens T, Diggle PJ, Faes C, Beenaerts N, Artois T, Giorgi E.

Sci Rep. 2019 Dec 13;9(1):19122. doi: 10.1038/s41598-019-55593-x.


Dynamic predictive probabilities to monitor rapid cystic fibrosis disease progression.

Szczesniak RD, Su W, Brokamp C, Keogh RH, Pestian JP, Seid M, Diggle PJ, Clancy JP.

Stat Med. 2020 Mar 15;39(6):740-756. doi: 10.1002/sim.8443. Epub 2019 Dec 9.


A real-time spatio-temporal syndromic surveillance system with application to small companion animals.

Hale AC, Sánchez-Vizcaíno F, Rowlingson B, Radford AD, Giorgi E, O'Brien SJ, Diggle PJ.

Sci Rep. 2019 Nov 28;9(1):17738. doi: 10.1038/s41598-019-53352-6.


Do pain, anxiety and depression influence quality of life for people with amyotrophic lateral sclerosis/motor neuron disease? A national study reconciling previous conflicting literature.

Edge R, Mills R, Tennant A, Diggle PJ, Young CA; TONiC study group.

J Neurol. 2020 Mar;267(3):607-615. doi: 10.1007/s00415-019-09615-3. Epub 2019 Nov 7. Erratum in: J Neurol. 2020 Jan 28;:.


Use of acoustic emission to identify novel candidate biomarkers for knee osteoarthritis (OA).

Schlüter DK, Spain L, Quan W, Southworth H, Platt N, Mercer J, Shark LK, Waterton JC, Bowes M, Diggle PJ, Dixon M, Huddleston J, Goodacre J.

PLoS One. 2019 Oct 16;14(10):e0223711. doi: 10.1371/journal.pone.0223711. eCollection 2019.


Apathy as a behavioural marker of cognitive impairment in Parkinson's disease: a longitudinal analysis.

Martin GP, McDonald KR, Allsop D, Diggle PJ, Leroi I.

J Neurol. 2020 Jan;267(1):214-227. doi: 10.1007/s00415-019-09538-z. Epub 2019 Oct 15.


Adjusting for spatial variation when assessing individual-level risk: A case-study in the epidemiology of snake-bite in Sri Lanka.

Ediriweera DS, Kasthuriratne A, Pathmeswaran A, Gunawardene NK, Jayamanne SF, Murray K, Iwamura T, Lalloo DG, de Silva HJ, Diggle PJ.

PLoS One. 2019 Oct 3;14(10):e0223021. doi: 10.1371/journal.pone.0223021. eCollection 2019.


A Fully Integrated Real-Time Detection, Diagnosis, and Control of Community Diarrheal Disease Clusters and Outbreaks (the INTEGRATE Project): Protocol for an Enhanced Surveillance System.

McIntyre KM, Bolton FJ, Christley RM, Cleary P, Deja E, Durie AE, Diggle PJ, Hughes DA, de Lusignan S, Orton L, Radford AD, Elliot AJ, Smith GE, Snape DA, Stanistreet D, Vivancos R, Winstanley C, O'Brien SJ.

JMIR Res Protoc. 2019 Sep 26;8(9):e13941. doi: 10.2196/13941.


A geostatistical framework for combining spatially referenced disease prevalence data from multiple diagnostics.

Amoah B, Diggle PJ, Giorgi E.

Biometrics. 2020 Mar;76(1):158-170. doi: 10.1111/biom.13142. Epub 2019 Oct 29.


Reassessment of the prevalence of soil-transmitted helminth infections in Sri Lanka to enable a more focused control programme: a cross-sectional national school survey with spatial modelling.

Ediriweera DS, Gunawardena S, Gunawardena NK, Iddawela D, Kannathasan S, Murugananthan A, Yahathugoda C, Pathmeswaran A, Diggle PJ, de Silva N.

Lancet Glob Health. 2019 Sep;7(9):e1237-e1246. doi: 10.1016/S2214-109X(19)30253-0. Epub 2019 Jul 19.


The influence of multiple episodes of acute kidney injury on survival and progression to end stage kidney disease in patients with chronic kidney disease.

Sykes L, Asar O, Ritchie J, Raman M, Vassallo D, Alderson HV, O'Donoghue DJ, Green D, Diggle PJ, Kalra PA.

PLoS One. 2019 Jul 18;14(7):e0219828. doi: 10.1371/journal.pone.0219828. eCollection 2019.


Domestic River Water Use and Risk of Typhoid Fever: Results From a Case-control Study in Blantyre, Malawi.

Gauld JS, Olgemoeller F, Nkhata R, Li C, Chirambo A, Morse T, Gordon MA, Read JM, Heyderman RS, Kennedy N, Diggle PJ, Feasey NA.

Clin Infect Dis. 2020 Mar 17;70(7):1278-1284. doi: 10.1093/cid/ciz405.


A Haemophilus sp. dominates the microbiota of sputum from UK adults with non-severe community acquired pneumonia and chronic lung disease.

Wootton DG, Cox MJ, Gloor GB, Litt D, Hoschler K, German E, Court J, Eneje O, Keogan L, Macfarlane L, Wilks S, Diggle PJ, Woodhead M, Moffatt MF, Cookson WOC, Gordon SB.

Sci Rep. 2019 Feb 20;9(1):2388. doi: 10.1038/s41598-018-38090-5.


Climate, human behaviour or environment: individual-based modelling of Campylobacter seasonality and strategies to reduce disease burden.

Rushton SP, Sanderson RA, Diggle PJ, Shirley MDF, Blain AP, Lake I, Maas JA, Reid WDK, Hardstaff J, Williams N, Jones NR, Rigby D, Strachan NJC, Forbes KJ, Hunter PR, Humphrey TJ, O'Brien SJ.

J Transl Med. 2019 Jan 21;17(1):34. doi: 10.1186/s12967-019-1781-y.


A pragmatic cluster randomised controlled trial of a tailored intervention to improve the initial management of suspected encephalitis.

Backman R, Foy R, Diggle PJ, Kneen R, Easton A, Defres S, McGill F, Michael BD, Solomon T; ENCEPH UK Programme Steering Committee.

PLoS One. 2018 Dec 6;13(12):e0202257. doi: 10.1371/journal.pone.0202257. eCollection 2018.


A spatial analysis of giardiasis and cryptosporidiosis in relation to public water supply distribution in North West England.

Reeve NF, Diggle PJ, Lamden K, Keegan T.

Spat Spatiotemporal Epidemiol. 2018 Nov;27:61-70. doi: 10.1016/j.sste.2018.09.002. Epub 2018 Oct 13.


Risk factors for social withdrawal in amyotrophic lateral sclerosis/motor neurone disease.

Schlüter DK, Tennant A, Mills R, Diggle PJ, Young CA.

Amyotroph Lateral Scler Frontotemporal Degener. 2018 Nov;19(7-8):591-598. doi: 10.1080/21678421.2018.1508477. Epub 2018 Nov 6.


Reducing contamination risk in cluster-randomized infectious disease-intervention trials.

McCann RS, van den Berg H, Takken W, Chetwynd AG, Giorgi E, Terlouw DJ, Diggle PJ.

Int J Epidemiol. 2018 Dec 1;47(6):2015-2024. doi: 10.1093/ije/dyy213.


Seasonal fluctuation of lung function in cystic fibrosis: A national register-based study in two northern European populations.

Qvist T, Schlüter DK, Rajabzadeh V, Diggle PJ, Pressler T, Carr SB, Taylor-Robinson D.

J Cyst Fibros. 2019 May;18(3):390-395. doi: 10.1016/j.jcf.2018.10.006. Epub 2018 Oct 19.


Evaluating temporal patterns of snakebite in Sri Lanka: the potential for higher snakebite burdens with climate change.

Ediriweera DS, Diggle PJ, Kasturiratne A, Pathmeswaran A, Gunawardena NK, Jayamanne SF, Isbister GK, Dawson A, Lalloo DG, de Silva HJ.

Int J Epidemiol. 2018 Dec 1;47(6):2049-2058. doi: 10.1093/ije/dyy188.


Fine-scale GPS tracking to quantify human movement patterns and exposure to leptospires in the urban slum environment.

Owers KA, Odetunde J, de Matos RB, Sacramento G, Carvalho M, Nery N Jr, Costa F, Reis MG, Childs JE, Hagan JE, Diggle PJ, Ko AI.

PLoS Negl Trop Dis. 2018 Aug 31;12(8):e0006752. doi: 10.1371/journal.pntd.0006752. eCollection 2018 Aug.


Impact of cystic fibrosis on birthweight: a population based study of children in Denmark and Wales.

Schlüter DK, Griffiths R, Adam A, Akbari A, Heaven ML, Paranjothy S, Nybo Andersen AM, Carr SB, Pressler T, Diggle PJ, Taylor-Robinson D.

Thorax. 2019 May;74(5):447-454. doi: 10.1136/thoraxjnl-2018-211706. Epub 2018 Jul 19.


A model for leptospire dynamics and control in the Norway rat (Rattus norvegicus) the reservoir host in urban slum environments.

Minter A, Diggle PJ, Costa F, Childs J, Ko AI, Begon M.

Epidemics. 2018 Dec;25:26-34. doi: 10.1016/j.epidem.2018.05.002. Epub 2018 May 5.


Quantification of Leptospira interrogans Survival in Soil and Water Microcosms.

Casanovas-Massana A, Pedra GG, Wunder EA Jr, Diggle PJ, Begon M, Ko AI.

Appl Environ Microbiol. 2018 Jun 18;84(13). pii: e00507-18. doi: 10.1128/AEM.00507-18. Print 2018 Jul 1.


Geostatistical modelling of the association between malaria and child growth in Africa.

Amoah B, Giorgi E, Heyes DJ, van Burren S, Diggle PJ.

Int J Health Geogr. 2018 Feb 27;17(1):7. doi: 10.1186/s12942-018-0127-y.


Spatial and temporal dynamics of pathogenic Leptospira in surface waters from the urban slum environment.

Casanovas-Massana A, Costa F, Riediger IN, Cunha M, de Oliveira D, Mota DC, Sousa E, Querino VA, Nery N Jr, Reis MG, Wunder EA Jr, Diggle PJ, Ko AI.

Water Res. 2018 Mar 1;130:176-184. doi: 10.1016/j.watres.2017.11.068. Epub 2017 Nov 30.


Spatial statistical modelling of capillary non-perfusion in the retina.

MacCormick IJC, Zheng Y, Czanner S, Zhao Y, Diggle PJ, Harding SP, Czanner G.

Sci Rep. 2017 Dec 1;7(1):16792. doi: 10.1038/s41598-017-16620-x.


Evidence of multiple intraspecific transmission routes for Leptospira acquisition in Norway rats (Rattus norvegicus).

Minter A, Diggle PJ, Costa F, Childs J, Ko AI, Begon M.

Epidemiol Infect. 2017 Dec;145(16):3438-3448. doi: 10.1017/S0950268817002539. Epub 2017 Nov 27.


The helminth community of a population of Rattus norvegicus from an urban Brazilian slum and the threat of zoonotic diseases.

Carvalho-Pereira T, Souza FN, Santos LRN, Walker R, Pertile AC, de Oliveira DS, Pedra GG, Minter A, Rodrigues MG, Bahiense TC, Reis MG, Diggle PJ, Ko AI, Childs JE, da Silva EM, Begon M, Costa F.

Parasitology. 2018 May;145(6):797-806. doi: 10.1017/S0031182017001755. Epub 2017 Nov 8.


Assessment of the effect of larval source management and house improvement on malaria transmission when added to standard malaria control strategies in southern Malawi: study protocol for a cluster-randomised controlled trial.

McCann RS, van den Berg H, Diggle PJ, van Vugt M, Terlouw DJ, Phiri KS, Di Pasquale A, Maire N, Gowelo S, Mburu MM, Kabaghe AN, Mzilahowa T, Chipeta MG, Takken W.

BMC Infect Dis. 2017 Sep 22;17(1):639. doi: 10.1186/s12879-017-2749-2.


Differences in survival among adults with HIV-associated Kaposi's sarcoma during routine HIV treatment initiation in Zomba district, Malawi: a retrospective cohort analysis.

Singogo E, Keegan TJ, Diggle PJ, van Lettow M, Matengeni A, van Oosterhout JJ, Sodhi S, Joshua M, Taylor BM.

Int Health. 2017 Sep 1;9(5):281-287. doi: 10.1093/inthealth/ihx027.


Surveillance in easy to access population subgroups as a tool for evaluating malaria control progress: A systematic review.

Sesay SSS, Giorgi E, Diggle PJ, Schellenberg D, Lalloo DG, Terlouw DJ.

PLoS One. 2017 Aug 16;12(8):e0183330. doi: 10.1371/journal.pone.0183330. eCollection 2017. Review.


Predicting Risk of Serious Bacterial Infections in Febrile Children in the Emergency Department.

Irwin AD, Grant A, Williams R, Kolamunnage-Dona R, Drew RJ, Paulus S, Jeffers G, Williams K, Breen R, Preston J, Appelbe D, Chesters C, Newland P, Marzouk O, McNamara PS, Diggle PJ, Carrol ED.

Pediatrics. 2017 Aug;140(2). pii: e20162853. doi: 10.1542/peds.2016-2853. Epub 2017 Jul 5.


A longitudinal modelling study estimates acute symptoms of community acquired pneumonia recover to baseline by 10 days.

Wootton DG, Dickinson L, Pertinez H, Court J, Eneje O, Keogan L, Macfarlane L, Wilks S, Gallagher J, Woodhead M, Gordon SB, Diggle PJ.

Eur Respir J. 2017 Jun 15;49(6). pii: 1602170. doi: 10.1183/13993003.02170-2016. Print 2017 Jun.


Modelling and forecasting spatio-temporal variation in the risk of chronic malnutrition among under-five children in Ghana.

Aheto JMK, Taylor BM, Keegan TJ, Diggle PJ.

Spat Spatiotemporal Epidemiol. 2017 Jun;21:37-46. doi: 10.1016/j.sste.2017.02.003. Epub 2017 Mar 2.


Web-based integrated bipolar parenting intervention for parents with bipolar disorder: a randomised controlled pilot trial.

Jones SH, Jovanoska J, Calam R, Wainwright LD, Vincent H, Asar O, Diggle PJ, Parker R, Long R, Sanders M, Lobban F.

J Child Psychol Psychiatry. 2017 Sep;58(9):1033-1041. doi: 10.1111/jcpp.12745. Epub 2017 May 16.


Modeling Seasonal and Spatiotemporal Variation: The Example of Respiratory Prescribing.

Sofianopoulou E, Pless-Mulloli T, Rushton S, Diggle PJ.

Am J Epidemiol. 2017 Jul 1;186(1):101-108. doi: 10.1093/aje/kww246.


Impact of metric and sample size on determining malaria hotspot boundaries.

Stresman GH, Giorgi E, Baidjoe A, Knight P, Odongo W, Owaga C, Shagari S, Makori E, Stevenson J, Drakeley C, Cox J, Bousema T, Diggle PJ.

Sci Rep. 2017 Apr 12;7:45849. doi: 10.1038/srep45849.


Assessing Feasibility and Acceptability of Web-Based Enhanced Relapse Prevention for Bipolar Disorder (ERPonline): A Randomized Controlled Trial.

Lobban F, Dodd AL, Sawczuk AP, Asar O, Dagnan D, Diggle PJ, Griffiths M, Honary M, Knowles D, Long R, Morriss R, Parker R, Jones S.

J Med Internet Res. 2017 Mar 24;19(3):e85. doi: 10.2196/jmir.7008.


A statistical model to describe longitudinal and correlated metabolic risk factors: the Whitehall II prospective study.

Breeze P, Squires H, Chilcott J, Stride C, Diggle PJ, Brunner E, Tabak A, Brennan A.

J Public Health (Oxf). 2016 Dec 2;38(4):679-687. doi: 10.1093/pubmed/fdv160. No abstract available.


The impact of Type 2 diabetes prevention programmes based on risk-identification and lifestyle intervention intensity strategies: a cost-effectiveness analysis.

Breeze PR, Thomas C, Squires H, Brennan A, Greaves C, Diggle PJ, Brunner E, Tabak A, Preston L, Chilcott J.

Diabet Med. 2017 May;34(5):632-640. doi: 10.1111/dme.13314. Epub 2017 Mar 10.


Using Community-Level Prevalence of Loa loa Infection to Predict the Proportion of Highly-Infected Individuals: Statistical Modelling to Support Lymphatic Filariasis and Onchocerciasis Elimination Programs.

Schlüter DK, Ndeffo-Mbah ML, Takougang I, Ukety T, Wanji S, Galvani AP, Diggle PJ.

PLoS Negl Trop Dis. 2016 Dec 1;10(12):e0005157. doi: 10.1371/journal.pntd.0005157. eCollection 2016 Dec.


Modeling of spatio-temporal variation in plague incidence in Madagascar from 1980 to 2007.

Giorgi E, Kreppel K, Diggle PJ, Caminade C, Ratsitorahina M, Rajerison M, Baylis M.

Spat Spatiotemporal Epidemiol. 2016 Nov;19:125-135. doi: 10.1016/j.sste.2016.10.001. Epub 2016 Oct 18.


Short-term and long-term effects of acute kidney injury in chronic kidney disease patients: A longitudinal analysis.

Asar Ö, Ritchie J, Kalra PA, Diggle PJ.

Biom J. 2016 Nov;58(6):1552-1566. doi: 10.1002/bimj.201500270. Epub 2016 Sep 14.


Safety of lumbar puncture in comatose children with clinical features of cerebral malaria.

Moxon CA, Zhao L, Li C, Seydel KB, MacCormick IJ, Diggle PJ, Mallewa M, Solomon T, Beare NA, Glover SJ, Harding SP, Lewallen S, Kampondeni S, Potchen MJ, Taylor TE, Postels DG.

Neurology. 2016 Nov 29;87(22):2355-2362. Epub 2016 Oct 28.


Recovery from pneumonia requires efferocytosis which is impaired in smokers and those with low body mass index and enhanced by statins.

Wootton DG, Diggle PJ, Court J, Eneje O, Keogan L, Macfarlane L, Wilks S, Woodhead M, Gordon SB.

Thorax. 2016 Nov;71(11):1052-1054. doi: 10.1136/thoraxjnl-2016-208505. Epub 2016 Jul 28.

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