Sort by
Items per page

Send to

Choose Destination

Search results

Items: 49


IL-4 and IL-17A Cooperatively Promote Hydrogen Peroxide Production, Oxidative DNA Damage, and Upregulation of Dual Oxidase 2 in Human Colon and Pancreatic Cancer Cells.

Wu Y, Konaté MM, Lu J, Makhlouf H, Chuaqui R, Antony S, Meitzler JL, Difilippantonio MJ, Liu H, Juhasz A, Jiang G, Dahan I, Roy K, Doroshow JH.

J Immunol. 2019 Nov 1;203(9):2532-2544. doi: 10.4049/jimmunol.1800469. Epub 2019 Sep 23.


Patterns of Chromosomal Aberrations in Solid Tumors.

Grade M, Difilippantonio MJ, Camps J.

Recent Results Cancer Res. 2015;200:115-42. doi: 10.1007/978-3-319-20291-4_6. Review.


Aneuploidy, oncogene amplification and epithelial to mesenchymal transition define spontaneous transformation of murine epithelial cells.

Padilla-Nash HM, McNeil NE, Yi M, Nguyen QT, Hu Y, Wangsa D, Mack DL, Hummon AB, Case C, Cardin E, Stephens R, Difilippantonio MJ, Ried T.

Carcinogenesis. 2013 Aug;34(8):1929-39. doi: 10.1093/carcin/bgt138. Epub 2013 Apr 25.


Genetic amplification of the NOTCH modulator LNX2 upregulates the WNT/β-catenin pathway in colorectal cancer.

Camps J, Pitt JJ, Emons G, Hummon AB, Case CM, Grade M, Jones TL, Nguyen QT, Ghadimi BM, Beissbarth T, Difilippantonio MJ, Caplen NJ, Ried T.

Cancer Res. 2013 Mar 15;73(6):2003-13. doi: 10.1158/0008-5472.CAN-12-3159. Epub 2013 Jan 14.


Exon 1 disruption alters tissue-specific expression of mouse p53 and results in selective development of B cell lymphomas.

Chiang YJ, Difilippantonio MJ, Tessarollo L, Morse HC, Hodes RJ.

PLoS One. 2012;7(11):e49305. doi: 10.1371/journal.pone.0049305. Epub 2012 Nov 14.


The rectal cancer microRNAome--microRNA expression in rectal cancer and matched normal mucosa.

Gaedcke J, Grade M, Camps J, Søkilde R, Kaczkowski B, Schetter AJ, Difilippantonio MJ, Harris CC, Ghadimi BM, Møller S, Beissbarth T, Ried T, Litman T.

Clin Cancer Res. 2012 Sep 15;18(18):4919-30. Epub 2012 Jul 31.


The consequences of chromosomal aneuploidy on the transcriptome of cancer cells.

Ried T, Hu Y, Difilippantonio MJ, Ghadimi BM, Grade M, Camps J.

Biochim Biophys Acta. 2012 Jul;1819(7):784-93. doi: 10.1016/j.bbagrm.2012.02.020. Epub 2012 Mar 6. Review.


Systems-wide RNAi analysis of CASP8AP2/FLASH shows transcriptional deregulation of the replication-dependent histone genes and extensive effects on the transcriptome of colorectal cancer cells.

Hummon AB, Pitt JJ, Camps J, Emons G, Skube SB, Huppi K, Jones TL, Beissbarth T, Kramer F, Grade M, Difilippantonio MJ, Ried T, Caplen NJ.

Mol Cancer. 2012 Jan 4;11:1. doi: 10.1186/1476-4598-11-1.


Decreased microRNA-214 levels in breast cancer cells coincides with increased cell proliferation, invasion and accumulation of the Polycomb Ezh2 methyltransferase.

Derfoul A, Juan AH, Difilippantonio MJ, Palanisamy N, Ried T, Sartorelli V.

Carcinogenesis. 2011 Nov;32(11):1607-14. doi: 10.1093/carcin/bgr184. Epub 2011 Aug 8.


HDAC2 and TXNL1 distinguish aneuploid from diploid colorectal cancers.

Gemoll T, Roblick UJ, Szymczak S, Braunschweig T, Becker S, Igl BW, Bruch HP, Ziegler A, Hellman U, Difilippantonio MJ, Ried T, Jörnvall H, Auer G, Habermann JK.

Cell Mol Life Sci. 2011 Oct;68(19):3261-74. doi: 10.1007/s00018-011-0628-3. Epub 2011 Feb 3.


A genomic strategy for the functional validation of colorectal cancer genes identifies potential therapeutic targets.

Grade M, Hummon AB, Camps J, Emons G, Spitzner M, Gaedcke J, Hoermann P, Ebner R, Becker H, Difilippantonio MJ, Ghadimi BM, Beissbarth T, Caplen NJ, Ried T.

Int J Cancer. 2011 Mar 1;128(5):1069-79. doi: 10.1002/ijc.25453.


Evaluating annotations of an Agilent expression chip suggests that many features cannot be interpreted.

Gertz EM, Sengupta K, Difilippantonio MJ, Ried T, Schäffer AA.

BMC Genomics. 2009 Nov 30;10:566. doi: 10.1186/1471-2164-10-566.


Definitive molecular cytogenetic characterization of 15 colorectal cancer cell lines.

Knutsen T, Padilla-Nash HM, Wangsa D, Barenboim-Stapleton L, Camps J, McNeil N, Difilippantonio MJ, Ried T.

Genes Chromosomes Cancer. 2010 Mar;49(3):204-23. doi: 10.1002/gcc.20730.


Nucleation capacity and presence of centrioles define a distinct category of centrosome abnormalities that induces multipolar mitoses in cancer cells.

Difilippantonio MJ, Ghadimi BM, Howard T, Camps J, Nguyen QT, Ferris DK, Sackett DL, Ried T.

Environ Mol Mutagen. 2009 Oct;50(8):672-96. doi: 10.1002/em.20532.


Integrative genomics reveals mechanisms of copy number alterations responsible for transcriptional deregulation in colorectal cancer.

Camps J, Nguyen QT, Padilla-Nash HM, Knutsen T, McNeil NE, Wangsa D, Hummon AB, Grade M, Ried T, Difilippantonio MJ.

Genes Chromosomes Cancer. 2009 Nov;48(11):1002-17. doi: 10.1002/gcc.20699.


Chromosomal copy number changes of locally advanced rectal cancers treated with preoperative chemoradiotherapy.

Grade M, Gaedcke J, Wangsa D, Varma S, Beckmann J, Liersch T, Hess C, Becker H, Difilippantonio MJ, Ried T, Ghadimi BM.

Cancer Genet Cytogenet. 2009 Aug;193(1):19-28. doi: 10.1016/j.cancergencyto.2009.03.016.


Chimeric IgH-TCRalpha/delta translocations in T lymphocytes mediated by RAG.

Callén E, Bunting S, Huang CY, Difilippantonio MJ, Wong N, Khor B, Mahowald G, Kruhlak MJ, Ried T, Sleckman BP, Nussenzweig A.

Cell Cycle. 2009 Aug;8(15):2408-12. Epub 2009 Aug 21.


Preoperative chemoradiotherapy in locally advanced rectal cancer: correlation of a gene expression-based response signature with recurrence.

Liersch T, Grade M, Gaedcke J, Varma S, Difilippantonio MJ, Langer C, Hess CF, Becker H, Ried T, Ghadimi BM.

Cancer Genet Cytogenet. 2009 Apr 15;190(2):57-65. doi: 10.1016/j.cancergencyto.2008.11.011.


Position of human chromosomes is conserved in mouse nuclei indicating a species-independent mechanism for maintaining genome organization.

Sengupta K, Camps J, Mathews P, Barenboim-Stapleton L, Nguyen QT, Difilippantonio MJ, Ried T.

Chromosoma. 2008 Oct;117(5):499-509. doi: 10.1007/s00412-008-0171-7. Epub 2008 Jun 18.


Microscopy and image analysis.

McNamara G, Difilippantonio MJ, Ried T.

Curr Protoc Hum Genet. 2005 Aug;Chapter 4:Unit 4.4. doi: 10.1002/0471142905.hg0404s46.


Chromosomal breakpoints in primary colon cancer cluster at sites of structural variants in the genome.

Camps J, Grade M, Nguyen QT, Hörmann P, Becker S, Hummon AB, Rodriguez V, Chandrasekharappa S, Chen Y, Difilippantonio MJ, Becker H, Ghadimi BM, Ried T.

Cancer Res. 2008 Mar 1;68(5):1284-95. doi: 10.1158/0008-5472.CAN-07-2864.


Beta-catenin expression results in p53-independent DNA damage and oncogene-induced senescence in prelymphomagenic thymocytes in vivo.

Xu M, Yu Q, Subrahmanyam R, Difilippantonio MJ, Ried T, Sen JM.

Mol Cell Biol. 2008 Mar;28(5):1713-23. Epub 2007 Dec 26.


Distinct domains in Nbs1 regulate irradiation-induced checkpoints and apoptosis.

Difilippantonio S, Celeste A, Kruhlak MJ, Lee Y, Difilippantonio MJ, Feigenbaum L, Jackson SP, McKinnon PJ, Nussenzweig A.

J Exp Med. 2007 May 14;204(5):1003-11. Epub 2007 May 3.


Spectral karyotyping analysis of human and mouse chromosomes.

Padilla-Nash HM, Barenboim-Stapleton L, Difilippantonio MJ, Ried T.

Nat Protoc. 2006;1(6):3129-42.


The XIST noncoding RNA functions independently of BRCA1 in X inactivation.

Xiao C, Sharp JA, Kawahara M, Davalos AR, Difilippantonio MJ, Hu Y, Li W, Cao L, Buetow K, Ried T, Chadwick BP, Deng CX, Panning B.

Cell. 2007 Mar 9;128(5):977-89.


Artificially introduced aneuploid chromosomes assume a conserved position in colon cancer cells.

Sengupta K, Upender MB, Barenboim-Stapleton L, Nguyen QT, Wincovitch SM Sr, Garfield SH, Difilippantonio MJ, Ried T.

PLoS One. 2007 Feb 7;2(2):e199.


Gene expression profiling reveals a massive, aneuploidy-dependent transcriptional deregulation and distinct differences between lymph node-negative and lymph node-positive colon carcinomas.

Grade M, Hörmann P, Becker S, Hummon AB, Wangsa D, Varma S, Simon R, Liersch T, Becker H, Difilippantonio MJ, Ghadimi BM, Ried T.

Cancer Res. 2007 Jan 1;67(1):41-56.


Autoreactive B cell responses to RNA-related antigens due to TLR7 gene duplication.

Pisitkun P, Deane JA, Difilippantonio MJ, Tarasenko T, Satterthwaite AB, Bolland S.

Science. 2006 Jun 16;312(5780):1669-72. Epub 2006 May 18.


Aneuploidy-dependent massive deregulation of the cellular transcriptome and apparent divergence of the Wnt/beta-catenin signaling pathway in human rectal carcinomas.

Grade M, Ghadimi BM, Varma S, Simon R, Wangsa D, Barenboim-Stapleton L, Liersch T, Becker H, Ried T, Difilippantonio MJ.

Cancer Res. 2006 Jan 1;66(1):267-82.


Two distinct activities contribute to human papillomavirus 16 E6's oncogenic potential.

Simonson SJ, Difilippantonio MJ, Lambert PF.

Cancer Res. 2005 Sep 15;65(18):8266-73.


A comprehensive continuous-time model for the appearance of CGH signal due to chromosomal missegregations during mitosis.

Desper R, Difilippantonio MJ, Ried T, Schäffer AA.

Math Biosci. 2005 Sep;197(1):67-87.


Effectiveness of gene expression profiling for response prediction of rectal adenocarcinomas to preoperative chemoradiotherapy.

Ghadimi BM, Grade M, Difilippantonio MJ, Varma S, Simon R, Montagna C, Füzesi L, Langer C, Becker H, Liersch T, Ried T.

J Clin Oncol. 2005 Mar 20;23(9):1826-38.


Molecular cytogenetics of mouse models of breast cancer.

Ried T, Dorritie K, Weaver Z, Wangsa D, Difilippantonio MJ, Montagna C.

Breast Dis. 2004;19:59-67. No abstract available.


Chromosome transfer induced aneuploidy results in complex dysregulation of the cellular transcriptome in immortalized and cancer cells.

Upender MB, Habermann JK, McShane LM, Korn EL, Barrett JC, Difilippantonio MJ, Ried T.

Cancer Res. 2004 Oct 1;64(19):6941-9.


Advanced molecular cytogenetics in human and mouse.

Dorritie K, Montagna C, Difilippantonio MJ, Ried T.

Expert Rev Mol Diagn. 2004 Sep;4(5):663-76. Review.


E6 and E7 oncoproteins induce distinct patterns of chromosomal aneuploidy in skin tumors from transgenic mice.

Schaeffer AJ, Nguyen M, Liem A, Lee D, Montagna C, Lambert PF, Ried T, Difilippantonio MJ.

Cancer Res. 2004 Jan 15;64(2):538-46.


H2AX haploinsufficiency modifies genomic stability and tumor susceptibility.

Celeste A, Difilippantonio S, Difilippantonio MJ, Fernandez-Capetillo O, Pilch DR, Sedelnikova OA, Eckhaus M, Ried T, Bonner WM, Nussenzweig A.

Cell. 2003 Aug 8;114(3):371-383.


Involvement of Crm1 in hepatitis B virus X protein-induced aberrant centriole replication and abnormal mitotic spindles.

Forgues M, Difilippantonio MJ, Linke SP, Ried T, Nagashima K, Feden J, Valerie K, Fukasawa K, Wang XW.

Mol Cell Biol. 2003 Aug;23(15):5282-92.


Evidence for replicative repair of DNA double-strand breaks leading to oncogenic translocation and gene amplification.

Difilippantonio MJ, Petersen S, Chen HT, Johnson R, Jasin M, Kanaar R, Ried T, Nussenzweig A.

J Exp Med. 2002 Aug 19;196(4):469-80.


In TH2 cells the Il4 gene has a series of accessibility states associated with distinctive probabilities of IL-4 production.

Guo L, Hu-Li J, Zhu J, Watson CJ, Difilippantonio MJ, Pannetier C, Paul WE.

Proc Natl Acad Sci U S A. 2002 Aug 6;99(16):10623-8. Epub 2002 Jul 29.


Genomic instability in mice lacking histone H2AX.

Celeste A, Petersen S, Romanienko PJ, Fernandez-Capetillo O, Chen HT, Sedelnikova OA, Reina-San-Martin B, Coppola V, Meffre E, Difilippantonio MJ, Redon C, Pilch DR, Olaru A, Eckhaus M, Camerini-Otero RD, Tessarollo L, Livak F, Manova K, Bonner WM, Nussenzweig MC, Nussenzweig A.

Science. 2002 May 3;296(5569):922-7. Epub 2002 Apr 4.


AID is required to initiate Nbs1/gamma-H2AX focus formation and mutations at sites of class switching.

Petersen S, Casellas R, Reina-San-Martin B, Chen HT, Difilippantonio MJ, Wilson PC, Hanitsch L, Celeste A, Muramatsuk M, Pilch DR, Redon C, Ried T, Bonner WM, Honjo T, Nussenzweig MC, Nussenzweig A.

Nature. 2001 Dec 6;414(6864):660-665. doi: 10.1038/414660a.


Response to RAG-mediated VDJ cleavage by NBS1 and gamma-H2AX.

Chen HT, Bhandoola A, Difilippantonio MJ, Zhu J, Brown MJ, Tai X, Rogakou EP, Brotz TM, Bonner WM, Ried T, Nussenzweig A.

Science. 2000 Dec 8;290(5498):1962-5.


DNA repair protein Ku80 suppresses chromosomal aberrations and malignant transformation.

Difilippantonio MJ, Zhu J, Chen HT, Meffre E, Nussenzweig MC, Max EE, Ried T, Nussenzweig A.

Nature. 2000 Mar 30;404(6777):510-4.


Centrosome amplification and instability occurs exclusively in aneuploid, but not in diploid colorectal cancer cell lines, and correlates with numerical chromosomal aberrations.

Ghadimi BM, Sackett DL, Difilippantonio MJ, Schröck E, Neumann T, Jauho A, Auer G, Ried T.

Genes Chromosomes Cancer. 2000 Feb;27(2):183-90.


A basic motif in the N-terminal region of RAG1 enhances V(D)J recombination activity.

McMahan CJ, Difilippantonio MJ, Rao N, Spanopoulou E, Schatz DG.

Mol Cell Biol. 1997 Aug;17(8):4544-52.


RAG1 mediates signal sequence recognition and recruitment of RAG2 in V(D)J recombination.

Difilippantonio MJ, McMahan CJ, Eastman QM, Spanopoulou E, Schatz DG.

Cell. 1996 Oct 18;87(2):253-62.


Physical and genetic maps for chromosome 10.

Lichter JB, Difilippantonio MJ, Pakstis AJ, Goodfellow PJ, Ward DC, Kidd KK.

Genomics. 1993 May;16(2):320-4.


Supplemental Content

Loading ...
Support Center