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Items: 7


Fluoroquinolone Efficacy against Tuberculosis Is Driven by Penetration into Lesions and Activity against Resident Bacterial Populations.

Sarathy J, Blanc L, Alvarez-Cabrera N, O'Brien P, Dias-Freedman I, Mina M, Zimmerman M, Kaya F, Ho Liang HP, Prideaux B, Dietzold J, Salgame P, Savic RM, Linderman J, Kirschner D, Pienaar E, Dartois V.

Antimicrob Agents Chemother. 2019 Apr 25;63(5). pii: e02516-18. doi: 10.1128/AAC.02516-18. Print 2019 May.


Toll-like Receptor 2 Prevents Neutrophil-Driven Immunopathology during Infection with Mycobacterium tuberculosis by Curtailing CXCL5 Production.

Gopalakrishnan A, Dietzold J, Verma S, Bhagavathula M, Salgame P.

Infect Immun. 2019 Feb 21;87(3). pii: e00760-18. doi: 10.1128/IAI.00760-18. Print 2019 Mar.


Comparing efficacies of moxifloxacin, levofloxacin and gatifloxacin in tuberculosis granulomas using a multi-scale systems pharmacology approach.

Pienaar E, Sarathy J, Prideaux B, Dietzold J, Dartois V, Kirschner DE, Linderman JJ.

PLoS Comput Biol. 2017 Aug 17;13(8):e1005650. doi: 10.1371/journal.pcbi.1005650. eCollection 2017 Aug.


Ethambutol Partitioning in Tuberculous Pulmonary Lesions Explains Its Clinical Efficacy.

Zimmerman M, Lestner J, Prideaux B, O'Brien P, Dias-Freedman I, Chen C, Dietzold J, Daudelin I, Kaya F, Blanc L, Chen PY, Park S, Salgame P, Sarathy J, Dartois V.

Antimicrob Agents Chemother. 2017 Aug 24;61(9). pii: e00924-17. doi: 10.1128/AAC.00924-17. Print 2017 Sep.


Divergent Functions of TLR2 on Hematopoietic and Nonhematopoietic Cells during Chronic Mycobacterium tuberculosis Infection.

Konowich J, Gopalakrishnan A, Dietzold J, Verma S, Bhatt K, Rafi W, Salgame P.

J Immunol. 2017 Jan 15;198(2):741-748. doi: 10.4049/jimmunol.1601651. Epub 2016 Dec 5.


Vaccine-mediated immunity to experimental Mycobacterium tuberculosis is not impaired in the absence of Toll-like receptor 9.

Gopalakrishnan A, Dietzold J, Salgame P.

Cell Immunol. 2016 Apr;302:11-18. doi: 10.1016/j.cellimm.2015.12.009. Epub 2015 Dec 30.


Duality of lipid mediators in host response against Mycobacterium tuberculosis: good cop, bad cop.

Dietzold J, Gopalakrishnan A, Salgame P.

F1000Prime Rep. 2015 Mar 3;7:29. doi: 10.12703/P7-29. eCollection 2015. Review.

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