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Items: 1 to 50 of 163

1.

The lipid droplet-associated protein ABHD5 protects the heart through proteolysis of HDAC4.

Jebessa ZH, Shanmukha Kumar D, Dewenter M, Lehmann LH, Xu C, Schreiter F, Siede D, Gong XM, Worst BC, Federico G, Sauer SW, Fischer T, Wechselberger L, Müller OJ, Sossalla S, Dieterich C, Most P, Gröne HJ, Moro C, Oberer M, Haemmerle G, Katus HA, Tyedmers J, Backs J.

Nat Metab. 2019 Nov;1(11):1157-1167. doi: 10.1038/s42255-019-0138-4. Epub 2019 Nov 15.

PMID:
31742248
2.

A secreted microRNA disrupts autophagy in distinct tissues of Caenorhabditis elegans upon ageing.

Zhou Y, Wang X, Song M, He Z, Cui G, Peng G, Dieterich C, Antebi A, Jing N, Shen Y.

Nat Commun. 2019 Oct 23;10(1):4827. doi: 10.1038/s41467-019-12821-2.

3.

Future projections of record-breaking sea surface temperature and cyanobacteria bloom events in the Baltic Sea.

Meier HEM, Dieterich C, Eilola K, Gröger M, Höglund A, Radtke H, Saraiva S, Wåhlström I.

Ambio. 2019 Nov;48(11):1362-1376. doi: 10.1007/s13280-019-01235-5. Epub 2019 Sep 10.

PMID:
31506843
4.

MedEx - Data Analytics for Medical Domain Experts in Real-Time.

Kindermann A, Stepanova E, Hund H, Geis N, Malone B, Dieterich C.

Stud Health Technol Inform. 2019 Sep 3;267:142-149. doi: 10.3233/SHTI190818.

PMID:
31483266
5.

Deep Learning Approaches Outperform Conventional Strategies in De-Identification of German Medical Reports.

Richter-Pechanski P, Amr A, Katus HA, Dieterich C.

Stud Health Technol Inform. 2019 Sep 3;267:101-109. doi: 10.3233/SHTI190813.

PMID:
31483261
6.

Stable Redox-Cycling Nitroxide Tempol Has Antifungal and Immune-Modulatory Properties.

Hosseinzadeh A, Stylianou M, Lopes JP, Müller DC, Häggman A, Holmberg S, Grumaz C, Johansson A, Sohn K, Dieterich C, Urban CF.

Front Microbiol. 2019 Aug 20;10:1843. doi: 10.3389/fmicb.2019.01843. eCollection 2019.

7.

On the optimal design of metabolic RNA labeling experiments.

Uvarovskii A, Naarmann-de Vries IS, Dieterich C.

PLoS Comput Biol. 2019 Aug 7;15(8):e1007252. doi: 10.1371/journal.pcbi.1007252. eCollection 2019 Aug.

8.

The E3 ubiquitin ligase UBR5 interacts with the H/ACA ribonucleoprotein complex and regulates ribosomal RNA biogenesis in embryonic stem cells.

Saez I, Gerbracht JV, Koyuncu S, Lee HJ, Horn M, Kroef V, Denzel MS, Dieterich C, Gehring NH, Vilchez D.

FEBS Lett. 2019 Jul 31. doi: 10.1002/1873-3468.13559. [Epub ahead of print]

PMID:
31365120
9.

A protein-RNA interaction atlas of the ribosome biogenesis factor AATF.

Kaiser RWJ, Ignarski M, Van Nostrand EL, Frese CK, Jain M, Cukoski S, Heinen H, Schaechter M, Seufert L, Bunte K, Frommolt P, Keller P, Helm M, Bohl K, Höhne M, Schermer B, Benzing T, Höpker K, Dieterich C, Yeo GW, Müller RU, Fabretti F.

Sci Rep. 2019 Jul 30;9(1):11071. doi: 10.1038/s41598-019-47552-3.

10.

Monitoring Cell-Type-Specific Gene Expression Using Ribosome Profiling In Vivo During Cardiac Hemodynamic Stress.

Doroudgar S, Hofmann C, Boileau E, Malone B, Riechert E, Gorska AA, Jakobi T, Sandmann C, Jürgensen L, Kmietczyk V, Malovrh E, Burghaus J, Rettel M, Stein F, Younesi F, Friedrich UA, Mauz V, Backs J, Kramer G, Katus HA, Dieterich C, Völkers M.

Circ Res. 2019 Aug 2;125(4):431-448. doi: 10.1161/CIRCRESAHA.119.314817. Epub 2019 Jul 9.

11.

m6A-mRNA methylation regulates cardiac gene expression and cellular growth.

Kmietczyk V, Riechert E, Kalinski L, Boileau E, Malovrh E, Malone B, Gorska A, Hofmann C, Varma E, Jürgensen L, Kamuf-Schenk V, Altmüller J, Tappu R, Busch M, Most P, Katus HA, Dieterich C, Völkers M.

Life Sci Alliance. 2019 Apr 9;2(2). pii: e201800233. doi: 10.26508/lsa.201800233. Print 2019 Apr.

12.

Loss of genomic integrity induced by lysosphingolipid imbalance drives ageing in the heart.

Ahuja G, Bartsch D, Yao W, Geissen S, Frank S, Aguirre A, Russ N, Messling JE, Dodzian J, Lagerborg KA, Vargas NE, Muck JS, Brodesser S, Baldus S, Sachinidis A, Hescheler J, Dieterich C, Trifunovic A, Papantonis A, Petrascheck M, Klinke A, Jain M, Valenzano DR, Kurian L.

EMBO Rep. 2019 Apr;20(4). pii: e47407. doi: 10.15252/embr.201847407. Epub 2019 Mar 18.

PMID:
30886000
13.

The RNA-Protein Interactome of Differentiated Kidney Tubular Epithelial Cells.

Ignarski M, Rill C, Kaiser RWJ, Kaldirim M, Neuhaus R, Esmaillie R, Li X, Klein C, Bohl K, Petersen M, Frese CK, Höhne M, Atanassov I, Rinschen MM, Höpker K, Schermer B, Benzing T, Dieterich C, Fabretti F, Müller RU.

J Am Soc Nephrol. 2019 Apr;30(4):564-576. doi: 10.1681/ASN.2018090914. Epub 2019 Mar 13.

PMID:
30867249
14.

Computational approaches for circular RNA analysis.

Jakobi T, Dieterich C.

Wiley Interdiscip Rev RNA. 2019 May;10(3):e1528. doi: 10.1002/wrna.1528. Epub 2019 Feb 20. Review.

PMID:
30788906
15.

Deregulated Splicing Is a Major Mechanism of RNA-Induced Toxicity in Huntington's Disease.

Schilling J, Broemer M, Atanassov I, Duernberger Y, Vorberg I, Dieterich C, Dagane A, Dittmar G, Wanker E, van Roon-Mom W, Winter J, Krauß S.

J Mol Biol. 2019 Apr 19;431(9):1869-1877. doi: 10.1016/j.jmb.2019.01.034. Epub 2019 Jan 31.

16.

ATF6 Regulates Cardiac Hypertrophy by Transcriptional Induction of the mTORC1 Activator, Rheb.

Blackwood EA, Hofmann C, Santo Domingo M, Bilal AS, Sarakki A, Stauffer W, Arrieta A, Thuerauf DJ, Kolkhorst FW, Müller OJ, Jakobi T, Dieterich C, Katus HA, Doroudgar S, Glembotski CC.

Circ Res. 2019 Jan 4;124(1):79-93. doi: 10.1161/CIRCRESAHA.118.313854.

PMID:
30582446
17.

A placental mammal-specific microRNA cluster acts as a natural brake for sociability in mice.

Lackinger M, Sungur AÖ, Daswani R, Soutschek M, Bicker S, Stemmler L, Wüst T, Fiore R, Dieterich C, Schwarting RK, Wöhr M, Schratt G.

EMBO Rep. 2019 Feb;20(2). pii: e46429. doi: 10.15252/embr.201846429. Epub 2018 Dec 14.

PMID:
30552145
18.

RNA Modification Level Estimation with pulseR.

Boileau E, Dieterich C.

Genes (Basel). 2018 Dec 10;9(12). pii: E619. doi: 10.3390/genes9120619.

19.

Identification of Methylated Transcripts Using the TRIBE Approach.

Worpenberg L, Jakobi T, Dieterich C, Roignant JY.

Methods Mol Biol. 2019;1870:89-106. doi: 10.1007/978-1-4939-8808-2_7.

PMID:
30539549
20.

circtools-a one-stop software solution for circular RNA research.

Jakobi T, Uvarovskii A, Dieterich C.

Bioinformatics. 2019 Jul 1;35(13):2326-2328. doi: 10.1093/bioinformatics/bty948.

21.

Identification and regulation of the long non-coding RNA Heat2 in heart failure.

Boeckel JN, Perret MF, Glaser SF, Seeger T, Heumüller AW, Chen W, John D, Kokot KE, Katus HA, Haas J, Lackner MK, Kayvanpour E, Grabe N, Dieterich C, von Haehling S, Ebner N, Hünecke S, Leuschner F, Fichtlscherer S, Meder B, Zeiher AM, Dimmeler S, Keller T.

J Mol Cell Cardiol. 2019 Jan;126:13-22. doi: 10.1016/j.yjmcc.2018.11.004. Epub 2018 Nov 13.

PMID:
30445017
22.

Exon Junction Complexes Suppress Spurious Splice Sites to Safeguard Transcriptome Integrity.

Boehm V, Britto-Borges T, Steckelberg AL, Singh KK, Gerbracht JV, Gueney E, Blazquez L, Altmüller J, Dieterich C, Gehring NH.

Mol Cell. 2018 Nov 1;72(3):482-495.e7. doi: 10.1016/j.molcel.2018.08.030.

23.

Circular RNAs in the cardiovascular system.

Gomes CPC, Salgado-Somoza A, Creemers EE, Dieterich C, Lustrek M, Devaux Y; Cardiolinc™ network.

Noncoding RNA Res. 2018 Feb 25;3(1):1-11. doi: 10.1016/j.ncrna.2018.02.002. eCollection 2018 Mar. Review.

24.

De-Identification of German Medical Admission Notes.

Richter-Pechanski P, Riezler S, Dieterich C.

Stud Health Technol Inform. 2018;253:165-169.

PMID:
30147065
25.

HiGHmed - An Open Platform Approach to Enhance Care and Research across Institutional Boundaries.

Haarbrandt B, Schreiweis B, Rey S, Sax U, Scheithauer S, Rienhoff O, Knaup-Gregori P, Bavendiek U, Dieterich C, Brors B, Kraus I, Thoms CM, Jäger D, Ellenrieder V, Bergh B, Yahyapour R, Eils R, Consortium H, Marschollek M.

Methods Inf Med. 2018 Jul;57(S 01):e66-e81. doi: 10.3414/ME18-02-0002. Epub 2018 Jul 17.

26.

A Vastly Increased Chemical Variety of RNA Modifications Containing a Thioacetal Structure.

Dal Magro C, Keller P, Kotter A, Werner S, Duarte V, Marchand V, Ignarski M, Freiwald A, Müller RU, Dieterich C, Motorin Y, Butter F, Atta M, Helm M.

Angew Chem Int Ed Engl. 2018 Jun 25;57(26):7893-7897. doi: 10.1002/anie.201713188. Epub 2018 Apr 27.

PMID:
29624844
27.

Insights into the ubiquitin-proteasome system of human embryonic stem cells.

Saez I, Koyuncu S, Gutierrez-Garcia R, Dieterich C, Vilchez D.

Sci Rep. 2018 Mar 6;8(1):4092. doi: 10.1038/s41598-018-22384-9.

28.

Deep Computational Circular RNA Analytics from RNA-seq Data.

Jakobi T, Dieterich C.

Methods Mol Biol. 2018;1724:9-25. doi: 10.1007/978-1-4939-7562-4_2.

PMID:
29322437
29.

A post-transcriptional program coordinated by CSDE1 prevents intrinsic neural differentiation of human embryonic stem cells.

Ju Lee H, Bartsch D, Xiao C, Guerrero S, Ahuja G, Schindler C, Moresco JJ, Yates JR 3rd, Gebauer F, Bazzi H, Dieterich C, Kurian L, Vilchez D.

Nat Commun. 2017 Nov 13;8(1):1456. doi: 10.1038/s41467-017-01744-5.

30.

Clinical genetics and outcome of left ventricular non-compaction cardiomyopathy.

Sedaghat-Hamedani F, Haas J, Zhu F, Geier C, Kayvanpour E, Liss M, Lai A, Frese K, Pribe-Wolferts R, Amr A, Li DT, Samani OS, Carstensen A, Bordalo DM, Müller M, Fischer C, Shao J, Wang J, Nie M, Yuan L, Haßfeld S, Schwartz C, Zhou M, Zhou Z, Shu Y, Wang M, Huang K, Zeng Q, Cheng L, Fehlmann T, Ehlermann P, Keller A, Dieterich C, Streckfuß-Bömeke K, Liao Y, Gotthardt M, Katus HA, Meder B.

Eur Heart J. 2017 Dec 7;38(46):3449-3460. doi: 10.1093/eurheartj/ehx545.

PMID:
29029073
31.

pulseR: Versatile computational analysis of RNA turnover from metabolic labeling experiments.

Uvarovskii A, Dieterich C.

Bioinformatics. 2017 Oct 15;33(20):3305-3307. doi: 10.1093/bioinformatics/btx368.

PMID:
29028260
32.

Cellular heterogeneity contributes to subtype-specific expression of ZEB1 in human glioblastoma.

Euskirchen P, Radke J, Schmidt MS, Schulze Heuling E, Kadikowski E, Maricos M, Knab F, Grittner U, Zerbe N, Czabanka M, Dieterich C, Miletic H, Mørk S, Koch A, Endres M, Harms C.

PLoS One. 2017 Sep 25;12(9):e0185376. doi: 10.1371/journal.pone.0185376. eCollection 2017.

33.

A proteomic atlas of insulin signalling reveals tissue-specific mechanisms of longevity assurance.

Tain LS, Sehlke R, Jain C, Chokkalingam M, Nagaraj N, Essers P, Rassner M, Grönke S, Froelich J, Dieterich C, Mann M, Alic N, Beyer A, Partridge L.

Mol Syst Biol. 2017 Sep 15;13(9):939. doi: 10.15252/msb.20177663.

34.

Dual RNA-seq reveals no plastic transcriptional response of the coccidian parasite Eimeria falciformis to host immune defenses.

Ehret T, Spork S, Dieterich C, Lucius R, Heitlinger E.

BMC Genomics. 2017 Sep 5;18(1):686. doi: 10.1186/s12864-017-4095-6.

35.

The cardiac microenvironment uses non-canonical WNT signaling to activate monocytes after myocardial infarction.

Meyer IS, Jungmann A, Dieterich C, Zhang M, Lasitschka F, Werkmeister S, Haas J, Müller OJ, Boutros M, Nahrendorf M, Katus HA, Hardt SE, Leuschner F.

EMBO Mol Med. 2017 Sep;9(9):1279-1293. doi: 10.15252/emmm.201707565.

36.

Identification of circular RNAs with host gene-independent expression in human model systems for cardiac differentiation and disease.

Siede D, Rapti K, Gorska AA, Katus HA, Altmüller J, Boeckel JN, Meder B, Maack C, Völkers M, Müller OJ, Backs J, Dieterich C.

J Mol Cell Cardiol. 2017 Aug;109:48-56. doi: 10.1016/j.yjmcc.2017.06.015. Epub 2017 Jul 1.

PMID:
28676412
37.

Flexbar 3.0 - SIMD and multicore parallelization.

Roehr JT, Dieterich C, Reinert K.

Bioinformatics. 2017 Sep 15;33(18):2941-2942. doi: 10.1093/bioinformatics/btx330.

PMID:
28541403
38.

A microRNA-129-5p/Rbfox crosstalk coordinates homeostatic downscaling of excitatory synapses.

Rajman M, Metge F, Fiore R, Khudayberdiev S, Aksoy-Aksel A, Bicker S, Ruedell Reschke C, Raoof R, Brennan GP, Delanty N, Farrell MA, O'Brien DF, Bauer S, Norwood B, Veno MT, Krüger M, Braun T, Kjems J, Rosenow F, Henshall DC, Dieterich C, Schratt G.

EMBO J. 2017 Jun 14;36(12):1770-1787. doi: 10.15252/embj.201695748. Epub 2017 May 9.

39.

FUCHS-towards full circular RNA characterization using RNAseq.

Metge F, Czaja-Hasse LF, Reinhardt R, Dieterich C.

PeerJ. 2017 Feb 28;5:e2934. doi: 10.7717/peerj.2934. eCollection 2017.

40.

Spatio-temporal dynamics of a fish predator: Density-dependent and hydrographic effects on Baltic Sea cod population.

Bartolino V, Tian H, Bergström U, Jounela P, Aro E, Dieterich C, Meier HE, Cardinale M, Bland B, Casini M.

PLoS One. 2017 Feb 16;12(2):e0172004. doi: 10.1371/journal.pone.0172004. eCollection 2017.

41.

Prognostic Relevance of Tumor Purity and Interaction with MGMT Methylation in Glioblastoma.

Schulze Heuling E, Knab F, Radke J, Eskilsson E, Martinez-Ledesma E, Koch A, Czabanka M, Dieterich C, Verhaak RG, Harms C, Euskirchen P.

Mol Cancer Res. 2017 May;15(5):532-540. doi: 10.1158/1541-7786.MCR-16-0322. Epub 2017 Feb 1.

42.

Bayesian prediction of RNA translation from ribosome profiling.

Malone B, Atanassov I, Aeschimann F, Li X, Großhans H, Dieterich C.

Nucleic Acids Res. 2017 Apr 7;45(6):2960-2972. doi: 10.1093/nar/gkw1350.

43.

JACUSA: site-specific identification of RNA editing events from replicate sequencing data.

Piechotta M, Wyler E, Ohler U, Landthaler M, Dieterich C.

BMC Bioinformatics. 2017 Jan 3;18(1):7. doi: 10.1186/s12859-016-1432-8.

44.

Somatic increase of CCT8 mimics proteostasis of human pluripotent stem cells and extends C. elegans lifespan.

Noormohammadi A, Khodakarami A, Gutierrez-Garcia R, Lee HJ, Koyuncu S, König T, Schindler C, Saez I, Fatima A, Dieterich C, Vilchez D.

Nat Commun. 2016 Nov 28;7:13649. doi: 10.1038/ncomms13649.

45.

Reducing RBM20 activity improves diastolic dysfunction and cardiac atrophy.

Hinze F, Dieterich C, Radke MH, Granzier H, Gotthardt M.

J Mol Med (Berl). 2016 Dec;94(12):1349-1358. doi: 10.1007/s00109-016-1483-3. Epub 2016 Nov 26.

46.

Analysis of cerebral glucose metabolism in patients with post-operative cognitive dysfunction.

Herter JM, Brenscheid N, Nienhaus L, Dieterich C, Weckesser M, VAN Aken H.

Minerva Anestesiol. 2017 Mar;83(3):337 - 338. doi: 10.23736/S0375-9393.16.11717-1. Epub 2016 Nov 3. No abstract available.

47.

SPIRE, a modular pipeline for eQTL analysis of RNA-Seq data, reveals a regulatory hotspot controlling miRNA expression in C. elegans.

Kel I, Chang Z, Galluccio N, Romeo M, Beretta S, Diomede L, Mezzelani A, Milanesi L, Dieterich C, Merelli I.

Mol Biosyst. 2016 Oct 18;12(11):3447-3458.

PMID:
27722582
48.

Mechanical regulation of transcription controls Polycomb-mediated gene silencing during lineage commitment.

Le HQ, Ghatak S, Yeung CY, Tellkamp F, Günschmann C, Dieterich C, Yeroslaviz A, Habermann B, Pombo A, Niessen CM, Wickström SA.

Nat Cell Biol. 2016 Aug;18(8):864-75. doi: 10.1038/ncb3387. Epub 2016 Jul 11.

PMID:
27398909
49.

A Single Transcriptome of a Green Toad (Bufo viridis) Yields Candidate Genes for Sex Determination and -Differentiation and Non-Anonymous Population Genetic Markers.

Gerchen JF, Reichert SJ, Röhr JT, Dieterich C, Kloas W, Stöck M.

PLoS One. 2016 May 27;11(5):e0156419. doi: 10.1371/journal.pone.0156419. eCollection 2016.

50.

Profiling and Validation of the Circular RNA Repertoire in Adult Murine Hearts.

Jakobi T, Czaja-Hasse LF, Reinhardt R, Dieterich C.

Genomics Proteomics Bioinformatics. 2016 Aug;14(4):216-23. doi: 10.1016/j.gpb.2016.02.003. Epub 2016 Apr 27.

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