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Items: 1 to 50 of 71

1.

Steroid-Responsive Relapsing-Remitting Neutrophilic Encephalitis: A Case Report.

Ungerer MN, Diem R, Wrede A, Huang K, Hähnel S, Wick W, Winkler F.

J Neuropathol Exp Neurol. 2018 Nov 1;77(11):993-996. doi: 10.1093/jnen/nly088.

PMID:
30299484
2.

Early auto-immune targeting of photoreceptor ribbon synapses in mouse models of multiple sclerosis.

Dembla M, Kesharwani A, Natarajan S, Fecher-Trost C, Fairless R, Williams SK, Flockerzi V, Diem R, Schwarz K, Schmitz F.

EMBO Mol Med. 2018 Sep 28. pii: e8926. doi: 10.15252/emmm.201808926. [Epub ahead of print]

3.

Anti-TNFR1 targeting in humanized mice ameliorates disease in a model of multiple sclerosis.

Williams SK, Fairless R, Maier O, Liermann PC, Pichi K, Fischer R, Eisel ULM, Kontermann R, Herrmann A, Weksler B, Romero N, Couraud PO, Pfizenmaier K, Diem R.

Sci Rep. 2018 Sep 11;8(1):13628. doi: 10.1038/s41598-018-31957-7.

4.

Selective Vulnerability of αOFF Retinal Ganglion Cells during Onset of Autoimmune Optic Neuritis.

Mayer C, Bruehl C, Salt EL, Diem R, Draguhn A, Fairless R.

Neuroscience. 2018 Aug 1. pii: S0306-4522(18)30515-3. doi: 10.1016/j.neuroscience.2018.07.040. [Epub ahead of print]

PMID:
30075244
5.

Gd contrast administration is dispensable in patients with MS without new T2 lesions on follow-up MRI.

Karimian-Jazi K, Wildemann B, Diem R, Schwarz D, Hielscher T, Wick W, Bendszus M, Breckwoldt MO.

Neurol Neuroimmunol Neuroinflamm. 2018 Jul 16;5(5):e480. doi: 10.1212/NXI.0000000000000480. eCollection 2018 Sep.

6.

Early Nodal and Paranodal Disruption in Autoimmune Optic Neuritis.

Stojic A, Bojcevski J, Williams SK, Diem R, Fairless R.

J Neuropathol Exp Neurol. 2018 May 1;77(5):361-373. doi: 10.1093/jnen/nly011.

PMID:
29444299
7.

Peripheral nerve involvement in multiple sclerosis: Demonstration by magnetic resonance neurography.

Jende JME, Hauck GH, Diem R, Weiler M, Heiland S, Wildemann B, Korporal-Kuhnke M, Wick W, Hayes JM, Pfaff J, Pham M, Bendszus M, Kollmer J.

Ann Neurol. 2017 Nov;82(5):676-685. doi: 10.1002/ana.25068. Epub 2017 Oct 26.

PMID:
29023976
8.

Failure of alemtuzumab therapy to control MOG encephalomyelitis.

Wildemann B, Jarius S, Schwarz A, Diem R, Viehöver A, Hähnel S, Reindl M, Korporal-Kuhnke M.

Neurology. 2017 Jul 11;89(2):207-209. doi: 10.1212/WNL.0000000000004087. Epub 2017 Jun 9. No abstract available.

PMID:
28600462
9.

Tryptophan-2,3-Dioxygenase (TDO) deficiency is associated with subclinical neuroprotection in a mouse model of multiple sclerosis.

Lanz TV, Williams SK, Stojic A, Iwantscheff S, Sonner JK, Grabitz C, Becker S, Böhler LI, Mohapatra SR, Sahm F, Küblbeck G, Nakamura T, Funakoshi H, Opitz CA, Wick W, Diem R, Platten M.

Sci Rep. 2017 Jan 24;7:41271. doi: 10.1038/srep41271.

10.

Murine Autoimmune Optic Neuritis Is Not Phenotypically Altered by the Retinal Degeneration 8 Mutation.

Stojic A, Fairless R, Beck SC, Sothilingam V, Weissgerber P, Wissenbach U, Gimmy V, Seeliger MW, Flockerzi V, Diem R, Williams SK.

Invest Ophthalmol Vis Sci. 2017 Jan 1;58(1):318-328. doi: 10.1167/iovs.16-20419.

PMID:
28114593
11.

Increasing the sensitivity of MRI for the detection of multiple sclerosis lesions by long axial coverage of the spinal cord: a prospective study in 119 patients.

Breckwoldt MO, Gradl J, Hähnel S, Hielscher T, Wildemann B, Diem R, Platten M, Wick W, Heiland S, Bendszus M.

J Neurol. 2017 Feb;264(2):341-349. doi: 10.1007/s00415-016-8353-3. Epub 2016 Dec 1.

PMID:
27909801
12.

Disease Activity and Conversion into Multiple Sclerosis after Optic Neuritis Is Treated with Erythropoietin.

Sühs KW, Papanagiotou P, Hein K, Pul R, Scholz K, Heesen C, Diem R.

Int J Mol Sci. 2016 Sep 30;17(10). pii: E1666.

13.

Brain Metabolite Changes in Patients with Relapsing-Remitting and Secondary Progressive Multiple Sclerosis: A Two-Year Follow-Up Study.

Obert D, Helms G, Sättler MB, Jung K, Kretzschmar B, Bähr M, Dechent P, Diem R, Hein K.

PLoS One. 2016 Sep 16;11(9):e0162583. doi: 10.1371/journal.pone.0162583. eCollection 2016.

14.

Sodium MRI in Multiple Sclerosis is Compatible with Intracellular Sodium Accumulation and Inflammation-Induced Hyper-Cellularity of Acute Brain Lesions.

Biller A, Pflugmann I, Badde S, Diem R, Wildemann B, Nagel AM, Jordan J, Benkhedah N, Kleesiek J.

Sci Rep. 2016 Aug 10;6:31269. doi: 10.1038/srep31269.

15.

[Immunomodulation and neuroprotection in optic neuritis].

Beisse F, Diem R.

Ophthalmologe. 2016 May;113(5):398-401. doi: 10.1007/s00347-016-0264-2. Review. German.

PMID:
27165274
16.

Treatment of optic neuritis with erythropoietin (TONE): a randomised, double-blind, placebo-controlled trial-study protocol.

Diem R, Molnar F, Beisse F, Gross N, Drüschler K, Heinrich SP, Joachimsen L, Rauer S, Pielen A, Sühs KW, Linker RA, Huchzermeyer C, Albrecht P, Hassenstein A, Aktas O, Guthoff T, Tonagel F, Kernstock C, Hartmann K, Kümpfel T, Hein K, van Oterendorp C, Grotejohann B, Ihorst G, Maurer J, Müller M, Volkmann M, Wildemann B, Platten M, Wick W, Heesen C, Schiefer U, Wolf S, Lagrèze WA.

BMJ Open. 2016 Mar 1;6(3):e010956. doi: 10.1136/bmjopen-2015-010956.

17.

[New aspects in the therapy of multiple sclerosis and optic neuritis].

Lagrèze W, Diem R.

Ophthalmologe. 2014 Aug;111(8):709-14. doi: 10.1007/s00347-013-2987-7. German.

PMID:
25063544
18.

N-methyl-D-aspartate receptor blockade is neuroprotective in experimental autoimmune optic neuritis.

Sühs KW, Fairless R, Williams SK, Heine K, Cavalié A, Diem R.

J Neuropathol Exp Neurol. 2014 Jun;73(6):507-18. doi: 10.1097/NEN.0000000000000073.

PMID:
24806299
19.

Antibody-mediated inhibition of TNFR1 attenuates disease in a mouse model of multiple sclerosis.

Williams SK, Maier O, Fischer R, Fairless R, Hochmeister S, Stojic A, Pick L, Haar D, Musiol S, Storch MK, Pfizenmaier K, Diem R.

PLoS One. 2014 Feb 28;9(2):e90117. doi: 10.1371/journal.pone.0090117. eCollection 2014.

20.

Risk factors for oxygen toxicity seizures in hyperbaric oxygen therapy: case reports from multiple institutions.

Seidel R, Carroll C, Thompson D, Diem RG, Yeboah K, Hayes AJ, Hall B, Whelan HT.

Undersea Hyperb Med. 2013 Nov-Dec;40(6):515-9.

PMID:
24377194
21.

Dysfunction of neuronal calcium signalling in neuroinflammation and neurodegeneration.

Fairless R, Williams SK, Diem R.

Cell Tissue Res. 2014 Aug;357(2):455-62. doi: 10.1007/s00441-013-1758-8. Epub 2013 Dec 11. Review.

PMID:
24326615
22.

[Clinically isolated syndrome].

Platten M, Lanz T, Bendszus M, Diem R.

Nervenarzt. 2013 Oct;84(10):1247-59. doi: 10.1007/s00115-013-3845-1. Review. German.

PMID:
24081277
23.

Neurological deficits caused by tissue hypoxia in neuroinflammatory disease.

Davies AL, Desai RA, Bloomfield PS, McIntosh PR, Chapple KJ, Linington C, Fairless R, Diem R, Kasti M, Murphy MP, Smith KJ.

Ann Neurol. 2013 Dec;74(6):815-25. doi: 10.1002/ana.24006. Epub 2013 Oct 17.

PMID:
24038279
24.

Calcium influx and calpain activation mediate preclinical retinal neurodegeneration in autoimmune optic neuritis.

Hoffmann DB, Williams SK, Bojcevski J, Müller A, Stadelmann C, Naidoo V, Bahr BA, Diem R, Fairless R.

J Neuropathol Exp Neurol. 2013 Aug;72(8):745-57. doi: 10.1097/NEN.0b013e31829c7370.

PMID:
23860028
25.

Comprehensive analysis of microRNA profiles in multiple sclerosis including next-generation sequencing.

Keller A, Leidinger P, Steinmeyer F, Stähler C, Franke A, Hemmrich-Stanisak G, Kappel A, Wright I, Dörr J, Paul F, Diem R, Tocariu-Krick B, Meder B, Backes C, Meese E, Ruprecht K.

Mult Scler. 2014 Mar;20(3):295-303. doi: 10.1177/1352458513496343. Epub 2013 Jul 8.

PMID:
23836875
26.

Membrane potential measurements of isolated neurons using a voltage-sensitive dye.

Fairless R, Beck A, Kravchenko M, Williams SK, Wissenbach U, Diem R, Cavalié A.

PLoS One. 2013;8(3):e58260. doi: 10.1371/journal.pone.0058260. Epub 2013 Mar 13.

27.

Retinal nerve fibre layer thinning in patients with clinically isolated optic neuritis and early treatment with interferon-beta.

Sühs KW, Hein K, Pehlke JR, Käsmann-Kellner B, Diem R.

PLoS One. 2012;7(12):e51645. doi: 10.1371/journal.pone.0051645. Epub 2012 Dec 13.

28.

A randomized, double-blind, phase 2 study of erythropoietin in optic neuritis.

Sühs KW, Hein K, Sättler MB, Görlitz A, Ciupka C, Scholz K, Käsmann-Kellner B, Papanagiotou P, Schäffler N, Restemeyer C, Bittersohl D, Hassenstein A, Seitz B, Reith W, Fassbender K, Hilgers R, Heesen C, Bähr M, Diem R.

Ann Neurol. 2012 Aug;72(2):199-210. doi: 10.1002/ana.23573.

PMID:
22926853
29.

Neuroinflammation by cytotoxic T-lymphocytes impairs retrograde axonal transport in an oligodendrocyte mutant mouse.

Ip CW, Kroner A, Groh J, Huber M, Klein D, Spahn I, Diem R, Williams SK, Nave KA, Edgar JM, Martini R.

PLoS One. 2012;7(8):e42554. doi: 10.1371/journal.pone.0042554. Epub 2012 Aug 8.

30.

Preclinical retinal neurodegeneration in a model of multiple sclerosis: The Journal of Neuroscience 2012; 32(16):5585-5597.

Fairless R, Williams SK, Hoffmann DB, Stojic A, Hochmeister S, Schmitz F, Storch MK, Diem R.

Ann Neurosci. 2012 Jul;19(3):121-2. doi: 10.5214/ans.0972.7531.190307. No abstract available.

31.

Mesenchymal stem cells protect CNS neurons against glutamate excitotoxicity by inhibiting glutamate receptor expression and function.

Voulgari-Kokota A, Fairless R, Karamita M, Kyrargyri V, Tseveleki V, Evangelidou M, Delorme B, Charbord P, Diem R, Probert L.

Exp Neurol. 2012 Jul;236(1):161-70. doi: 10.1016/j.expneurol.2012.04.011. Epub 2012 Apr 25.

PMID:
22561409
32.

Preclinical retinal neurodegeneration in a model of multiple sclerosis.

Fairless R, Williams SK, Hoffmann DB, Stojic A, Hochmeister S, Schmitz F, Storch MK, Diem R.

J Neurosci. 2012 Apr 18;32(16):5585-97. doi: 10.1523/JNEUROSCI.5705-11.2012.

33.

Impaired CD4+ cell recovery during antiretroviral therapy in patients with HIV resistance mutations.

Sühs KW, Stoll M, Diem R, Schmidt RE, Heiken H.

Arch Virol. 2012 Mar;157(3):433-40. doi: 10.1007/s00705-011-1191-9. Epub 2011 Dec 18.

PMID:
22179846
34.

An optical coherence tomography study on degeneration of retinal nerve fiber layer in rats with autoimmune optic neuritis.

Hein K, Gadjanski I, Kretzschmar B, Lange K, Diem R, Sättler MB, Bähr M.

Invest Ophthalmol Vis Sci. 2012 Jan 20;53(1):157-63. doi: 10.1167/iovs.11-8092.

PMID:
22131393
35.

Neuroprotective effects of the cellular prion protein in autoimmune optic neuritis.

Williams SK, Fairless R, Weise J, Kalinke U, Schulz-Schaeffer W, Diem R.

Am J Pathol. 2011 Jun;178(6):2823-31. doi: 10.1016/j.ajpath.2011.02.046.

36.

Correlation of optical coherence tomography with clinical and histopathological findings in experimental autoimmune uveoretinitis.

Gadjanski I, Williams SK, Hein K, Sättler MB, Bähr M, Diem R.

Exp Eye Res. 2011 Jul;93(1):82-90. doi: 10.1016/j.exer.2011.04.012. Epub 2011 May 11.

PMID:
21586286
37.

Anti-inflammatory effects of FTY720 do not prevent neuronal cell loss in a rat model of optic neuritis.

Rau CR, Hein K, Sättler MB, Kretzschmar B, Hillgruber C, McRae BL, Diem R, Bähr M.

Am J Pathol. 2011 Apr;178(4):1770-81. doi: 10.1016/j.ajpath.2011.01.003. Epub 2011 Feb 26.

38.

Role of n-type voltage-dependent calcium channels in autoimmune optic neuritis.

Gadjanski I, Boretius S, Williams SK, Lingor P, Knöferle J, Sättler MB, Fairless R, Hochmeister S, Sühs KW, Michaelis T, Frahm J, Storch MK, Bähr M, Diem R.

Ann Neurol. 2009 Jul;66(1):81-93. doi: 10.1002/ana.21668.

PMID:
19670438
39.

Flupirtine as neuroprotective add-on therapy in autoimmune optic neuritis.

Sättler MB, Williams SK, Neusch C, Otto M, Pehlke JR, Bähr M, Diem R.

Am J Pathol. 2008 Nov;173(5):1496-507. doi: 10.2353/ajpath.2008.080491. Epub 2008 Oct 2.

40.

Autoimmune optic neuritis in the common marmoset monkey: comparison of visual evoked potentials with MRI and histopathology.

Diem R, Demmer I, Boretius S, Merkler D, Schmelting B, Williams SK, Sättler MB, Bähr M, Michaelis T, Frahm J, Brück W, Fuchs E.

Invest Ophthalmol Vis Sci. 2008 Aug;49(8):3707-14. doi: 10.1167/iovs.08-1896. Epub 2008 Apr 30.

PMID:
18450589
41.

MRI of optic neuritis in a rat model.

Boretius S, Gadjanski I, Demmer I, Bähr M, Diem R, Michaelis T, Frahm J.

Neuroimage. 2008 Jun;41(2):323-34. doi: 10.1016/j.neuroimage.2008.02.021. Epub 2008 Feb 29.

PMID:
18394926
42.

Biological markers for axonal degeneration in CSF and blood of patients with the first event indicative for multiple sclerosis.

Hein Née Maier K, Köhler A, Diem R, Sättler MB, Demmer I, Lange P, Bähr M, Otto M.

Neurosci Lett. 2008 May 2;436(1):72-6. doi: 10.1016/j.neulet.2008.02.064. Epub 2008 Mar 5.

PMID:
18359164
43.

Strain-specific susceptibility for neurodegeneration in a rat model of autoimmune optic neuritis.

Sättler MB, Togni M, Gadjanski I, Sühs KW, Meyer N, Bähr M, Diem R.

J Neuroimmunol. 2008 Jan;193(1-2):77-86. Epub 2007 Nov 26.

PMID:
18037506
44.

Multiple neuroprotective mechanisms of minocycline in autoimmune CNS inflammation.

Maier K, Merkler D, Gerber J, Taheri N, Kuhnert AV, Williams SK, Neusch C, Bähr M, Diem R.

Neurobiol Dis. 2007 Mar;25(3):514-25. Epub 2007 Jan 18.

PMID:
17239606
45.

Neurodegeneration and -protection in autoimmune CNS inflammation.

Diem R, Sättler MB, Bähr M.

J Neuroimmunol. 2007 Mar;184(1-2):27-36. Epub 2006 Dec 26. Review.

PMID:
17188756
46.

Effects of glatiramer acetate and interferon-beta on neurodegeneration in a model of multiple sclerosis: a comparative study.

Maier K, Kuhnert AV, Taheri N, Sättler MB, Storch MK, Williams SK, Bähr M, Diem R.

Am J Pathol. 2006 Oct;169(4):1353-64.

47.

Effects of interferon-beta-1a on neuronal survival under autoimmune inflammatory conditions.

Sättler MB, Demmer I, Williams SK, Maier K, Merkler D, Gadjanski I, Stadelmann C, Bähr M, Diem R.

Exp Neurol. 2006 Sep;201(1):172-81. Epub 2006 Jun 9.

PMID:
16764858
48.

The LPS receptor, CD14, in experimental autoimmune encephalomyelitis and multiple sclerosis.

Walter S, Doering A, Letiembre M, Liu Y, Hao W, Diem R, Bernreuther C, Glatzel M, Engelhardt B, Fassbender K.

Cell Physiol Biochem. 2006;17(3-4):167-72. Epub 2006 Mar 14.

49.

Tau, phospho-tau, and S-100B in the cerebrospinal fluid of children with multiple sclerosis.

Rostasy K, Withut E, Pohl D, Lange P, Ciesielcyk B, Diem R, Gärtner J, Otto M.

J Child Neurol. 2005 Oct;20(10):822-5.

PMID:
16417878
50.

[Recent advances in pathogenesis and therapy of multiple sclerosis].

Linker RA, Stadelmann C, Diem R, Bähr M, Brück W, Gold R.

Fortschr Neurol Psychiatr. 2005 Dec;73(12):715-27. Review. German.

PMID:
16355314

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