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Protection of healthcare workers against transmission of Mycobacterium tuberculosis in hospitals: a review of the evidence.

Diel R, Nienhaus A, Witte P, Ziegler R.

ERJ Open Res. 2020 Mar 16;6(1). pii: 00317-2019. doi: 10.1183/23120541.00317-2019. eCollection 2020 Jan. Review.


Is adding fluoroquinolones to regimens for treating isoniazid-resistant tuberculosis necessary?

Diel R, Schluger NW.

Eur Respir J. 2019 Oct 10;54(4). pii: 1901494. doi: 10.1183/13993003.01494-2019. Print 2019 Oct. No abstract available.


Intersectoral Cost of Treating Pulmonary Non-Tuberculosis Mycobacterial Disease (NTM-PD) in Germany-A Change of Perspective in Disease Management.

Diel R, Mertsch P.

Int J Environ Res Public Health. 2019 Oct 9;16(20). pii: E3795. doi: 10.3390/ijerph16203795.


Accuracy of whole-genome sequencing to determine recent tuberculosis transmission: an 11-year population-based study in Hamburg, Germany.

Diel R, Kohl TA, Maurer FP, Merker M, Meywald Walter K, Hannemann J, Nienhaus A, Supply P, Niemann S.

Eur Respir J. 2019 Nov 28;54(5). pii: 1901154. doi: 10.1183/13993003.01154-2019. Print 2019 Nov. No abstract available.


Increasing bronchiectasis prevalence in Germany, 2009-2017: a population-based cohort study.

Ringshausen FC, Rademacher J, Pink I, de Roux A, Hickstein L, Ploner T, Welte T, Diel R.

Eur Respir J. 2019 Dec 4;54(6). pii: 1900499. doi: 10.1183/13993003.00499-2019. Print 2019 Dec. No abstract available.


Cost-Benefit Analysis of Real-Time Influenza Testing for Patients in German Emergency Rooms.

Diel R, Nienhaus A.

Int J Environ Res Public Health. 2019 Jul 3;16(13). pii: E2368. doi: 10.3390/ijerph16132368.


[Joint Statement on the New WHO Recommendations for Treatment of Multidrug- and Rifampicin-Resistant Tuberculosis].

Maurer FP, Bauer T, Diel R, Häcker B, Lange C, Niemann S, Otto-Knapp R, Schönfeld N.

Pneumologie. 2019 May;73(5):270-273. doi: 10.1055/a-0880-9987. Epub 2019 May 13. German. No abstract available.


Incidence of patients with non-cystic fibrosis bronchiectasis in Germany - A healthcare insurance claims data analysis.

Diel R, Ewig S, Blaas S, Jacob C, Juelich F, Korfmann G, Sohrab S, Sutharsan S, Rademacher J.

Respir Med. 2019 May;151:121-127. doi: 10.1016/j.rmed.2019.04.007. Epub 2019 Apr 9.


Individuals with migraine have a different dry eye symptom profile than individuals without migraine.

Farhangi M, Diel RJ, Buse DC, Huang AM, Levitt RC, Sarantopoulos CD, Felix ER, Galor A.

Br J Ophthalmol. 2020 Feb;104(2):260-264. doi: 10.1136/bjophthalmol-2018-313471. Epub 2019 Apr 30.


The economic burden of bronchiectasis - known and unknown: a systematic review.

Goeminne PC, Hernandez F, Diel R, Filonenko A, Hughes R, Juelich F, Solomon GM, Upton A, Wichmann K, Xu W, Chalmers JD.

BMC Pulm Med. 2019 Feb 28;19(1):54. doi: 10.1186/s12890-019-0818-6.


SNP-IT Tool for Identifying Subspecies and Associated Lineages of Mycobacterium tuberculosis Complex.

Lipworth S, Jajou R, de Neeling A, Bradley P, van der Hoek W, Maphalala G, Bonnet M, Sanchez-Padilla E, Diel R, Niemann S, Iqbal Z, Smith G, Peto T, Crook D, Walker T, van Soolingen D.

Emerg Infect Dis. 2019 Mar;25(3):482-488. doi: 10.3201/eid2503.180894.


Economic burden of bronchiectasis in Germany.

Diel R, Chalmers JD, Rabe KF, Nienhaus A, Loddenkemper R, Ringshausen FC.

Eur Respir J. 2019 Feb 28;53(2). pii: 1802033. doi: 10.1183/13993003.02033-2018. Print 2019 Feb.


Compensatory evolution drives multidrug-resistant tuberculosis in Central Asia.

Merker M, Barbier M, Cox H, Rasigade JP, Feuerriegel S, Kohl TA, Diel R, Borrell S, Gagneux S, Nikolayevskyy V, Andres S, Nübel U, Supply P, Wirth T, Niemann S.

Elife. 2018 Oct 30;7. pii: e38200. doi: 10.7554/eLife.38200.


Escaping the Plato's cave of latent tuberculosis testing: a path for developers of predictive tests for risk of tuberculosis.

Ruhwald M, Diel R.

Eur Respir J. 2018 Oct 25;52(4). pii: 1801616. doi: 10.1183/13993003.01616-2018. Print 2018 Oct. No abstract available.


Prediction of Susceptibility to First-Line Tuberculosis Drugs by DNA Sequencing.

CRyPTIC Consortium and the 100,000 Genomes Project, Allix-Béguec C, Arandjelovic I, Bi L, Beckert P, Bonnet M, Bradley P, Cabibbe AM, Cancino-Muñoz I, Caulfield MJ, Chaiprasert A, Cirillo DM, Clifton DA, Comas I, Crook DW, De Filippo MR, de Neeling H, Diel R, Drobniewski FA, Faksri K, Farhat MR, Fleming J, Fowler P, Fowler TA, Gao Q, Gardy J, Gascoyne-Binzi D, Gibertoni-Cruz AL, Gil-Brusola A, Golubchik T, Gonzalo X, Grandjean L, He G, Guthrie JL, Hoosdally S, Hunt M, Iqbal Z, Ismail N, Johnston J, Khanzada FM, Khor CC, Kohl TA, Kong C, Lipworth S, Liu Q, Maphalala G, Martinez E, Mathys V, Merker M, Miotto P, Mistry N, Moore DAJ, Murray M, Niemann S, Omar SV, Ong RT, Peto TEA, Posey JE, Prammananan T, Pym A, Rodrigues C, Rodrigues M, Rodwell T, Rossolini GM, Sánchez Padilla E, Schito M, Shen X, Shendure J, Sintchenko V, Sloutsky A, Smith EG, Snyder M, Soetaert K, Starks AM, Supply P, Suriyapol P, Tahseen S, Tang P, Teo YY, Thuong TNT, Thwaites G, Tortoli E, van Soolingen D, Walker AS, Walker TM, Wilcox M, Wilson DJ, Wyllie D, Yang Y, Zhang H, Zhao Y, Zhu B.

N Engl J Med. 2018 Oct 11;379(15):1403-1415. doi: 10.1056/NEJMoa1800474. Epub 2018 Sep 26.


Photophobia and sensations of dryness in patients with migraine occur independent of baseline tear volume and improve following botulinum toxin A injections.

Diel RJ, Hwang J, Kroeger ZA, Levitt RC, Sarantopoulos CD, Sered H, Felix ER, Martinez-Barrizonte J, Galor A.

Br J Ophthalmol. 2019 Aug;103(8):1024-1029. doi: 10.1136/bjophthalmol-2018-312649. Epub 2018 Sep 29.


The cost of Mycobacterium avium complex lung disease in Canada, France, Germany, and the United Kingdom: a nationally representative observational study.

Goring SM, Wilson JB, Risebrough NR, Gallagher J, Carroll S, Heap KJ, Obradovic M, Loebinger MR, Diel R.

BMC Health Serv Res. 2018 Sep 10;18(1):700. doi: 10.1186/s12913-018-3489-8.


Harmonized Genome Wide Typing of Tubercle Bacilli Using a Web-Based Gene-By-Gene Nomenclature System.

Kohl TA, Harmsen D, Rothgänger J, Walker T, Diel R, Niemann S.

EBioMedicine. 2018 Aug;34:131-138. doi: 10.1016/j.ebiom.2018.07.030. Epub 2018 Aug 13.


High mortality in patients with Mycobacterium avium complex lung disease: a systematic review.

Diel R, Lipman M, Hoefsloot W.

BMC Infect Dis. 2018 May 3;18(1):206. doi: 10.1186/s12879-018-3113-x.


Risk of tuberculosis transmission among healthcare workers.

Diel R, Niemann S, Nienhaus A.

ERJ Open Res. 2018 Apr 9;4(2). pii: 00161-2017. doi: 10.1183/23120541.00161-2017. eCollection 2018 Apr.


Adolescents and young adults: a neglected population group for tuberculosis surveillance.

García-Basteiro AL, Schaaf HS, Diel R, Migliori GB.

Eur Respir J. 2018 Feb 21;51(2). pii: 1800176. doi: 10.1183/13993003.00176-2018. Print 2018 Feb. No abstract available.


Microbiologic Outcome of Interventions Against Mycobacterium avium Complex Pulmonary Disease: A Systematic Review.

Diel R, Nienhaus A, Ringshausen FC, Richter E, Welte T, Rabe KF, Loddenkemper R.

Chest. 2018 Apr;153(4):888-921. doi: 10.1016/j.chest.2018.01.024. Epub 2018 Feb 2.


Botulinum Toxin A for the Treatment of Photophobia and Dry Eye.

Diel RJ, Kroeger ZA, Levitt RC, Sarantopoulos C, Sered H, Martinez-Barrizonte J, Galor A.

Ophthalmology. 2018 Jan;125(1):139-140. doi: 10.1016/j.ophtha.2017.09.031. Epub 2017 Oct 27. No abstract available.


Role of Alanine Racemase Mutations in Mycobacterium tuberculosis d-Cycloserine Resistance.

Nakatani Y, Opel-Reading HK, Merker M, Machado D, Andres S, Kumar SS, Moradigaravand D, Coll F, Perdigão J, Portugal I, Schön T, Nair D, Devi KRU, Kohl TA, Beckert P, Clark TG, Maphalala G, Khumalo D, Diel R, Klaos K, Aung HL, Cook GM, Parkhill J, Peacock SJ, Swaminathan S, Viveiros M, Niemann S, Krause KL, Köser CU.

Antimicrob Agents Chemother. 2017 Nov 22;61(12). pii: e01575-17. doi: 10.1128/AAC.01575-17. Print 2017 Dec.


Pulmonary disease by non-tuberculous mycobacteria - clinical management, unmet needs and future perspectives.

Larsson LO, Polverino E, Hoefsloot W, Codecasa LR, Diel R, Jenkins SG, Loebinger MR.

Expert Rev Respir Med. 2017 Dec;11(12):977-989. doi: 10.1080/17476348.2017.1386563. Epub 2017 Oct 10. Review.


Long-term Effect of Bacille Calmette-Guérin Vaccination in Tuberculin Skin Testing: A New Reality for TB Prevention.

Diel R.

Chest. 2017 Aug;152(2):235-236. doi: 10.1016/j.chest.2017.03.011. No abstract available.


[Tuberculosis Guideline for Adults - Guideline for Diagnosis and Treatment of Tuberculosis including LTBI Testing and Treatment of the German Central Committee (DZK) and the German Respiratory Society (DGP)].

Schaberg T, Bauer T, Brinkmann F, Diel R, Feiterna-Sperling C, Haas W, Hartmann P, Hauer B, Heyckendorf J, Lange C, Nienhaus A, Otto-Knapp R, Priwitzer M, Richter E, Rumetshofer R, Schenkel K, Schoch OD, Schönfeld N, Stahlmann R.

Pneumologie. 2017 Jun;71(6):325-397. doi: 10.1055/s-0043-105954. Epub 2017 Jun 26. German.


Microbiological and Clinical Outcomes of Treating Non-Mycobacterium Avium Complex Nontuberculous Mycobacterial Pulmonary Disease: A Systematic Review and Meta-Analysis.

Diel R, Ringshausen F, Richter E, Welker L, Schmitz J, Nienhaus A.

Chest. 2017 Jul;152(1):120-142. doi: 10.1016/j.chest.2017.04.166. Epub 2017 Apr 28. Review.


Burden of non-tuberculous mycobacterial pulmonary disease in Germany.

Diel R, Jacob J, Lampenius N, Loebinger M, Nienhaus A, Rabe KF, Ringshausen FC.

Eur Respir J. 2017 Apr 26;49(4). pii: 1602109. doi: 10.1183/13993003.02109-2016. Print 2017 Apr.


Screening for Methicillin-resistant Staphylococcus aureus in a residence home for elderly in Germany.

Becker J, Diel R.

J Occup Med Toxicol. 2017 Feb 3;12:3. doi: 10.1186/s12995-017-0149-6. eCollection 2017.


Some Synonymous and Nonsynonymous gyrA Mutations in Mycobacterium tuberculosis Lead to Systematic False-Positive Fluoroquinolone Resistance Results with the Hain GenoType MTBDRsl Assays.

Ajileye A, Alvarez N, Merker M, Walker TM, Akter S, Brown K, Moradigaravand D, Schön T, Andres S, Schleusener V, Omar SV, Coll F, Huang H, Diel R, Ismail N, Parkhill J, de Jong BC, Peto TE, Crook DW, Niemann S, Robledo J, Smith EG, Peacock SJ, Köser CU.

Antimicrob Agents Chemother. 2017 Mar 24;61(4). pii: e02169-16. doi: 10.1128/AAC.02169-16. Print 2017 Apr.


Yield of chest X-ray tuberculosis screening of immigrants during the European refugee crisis of 2015: a single-centre experience.

Weinrich JM, Diel R, Sauer M, Henes FO, Meywald-Walter K, Adam G, Schön G, Bannas P.

Eur Radiol. 2017 Aug;27(8):3244-3248. doi: 10.1007/s00330-016-4684-9. Epub 2017 Jan 3.


Risk for latent and active tuberculosis in Germany.

Herzmann C, Sotgiu G, Bellinger O, Diel R, Gerdes S, Goetsch U, Heykes-Uden H, Schaberg T, Lange C; TB or not TB consortium.

Infection. 2017 Jun;45(3):283-290. doi: 10.1007/s15010-016-0963-2. Epub 2016 Nov 19.


Mycobacterium tuberculosis lineage 4 comprises globally distributed and geographically restricted sublineages.

Stucki D, Brites D, Jeljeli L, Coscolla M, Liu Q, Trauner A, Fenner L, Rutaihwa L, Borrell S, Luo T, Gao Q, Kato-Maeda M, Ballif M, Egger M, Macedo R, Mardassi H, Moreno M, Tudo Vilanova G, Fyfe J, Globan M, Thomas J, Jamieson F, Guthrie JL, Asante-Poku A, Yeboah-Manu D, Wampande E, Ssengooba W, Joloba M, Henry Boom W, Basu I, Bower J, Saraiva M, Vaconcellos SEG, Suffys P, Koch A, Wilkinson R, Gail-Bekker L, Malla B, Ley SD, Beck HP, de Jong BC, Toit K, Sanchez-Padilla E, Bonnet M, Gil-Brusola A, Frank M, Penlap Beng VN, Eisenach K, Alani I, Wangui Ndung'u P, Revathi G, Gehre F, Akter S, Ntoumi F, Stewart-Isherwood L, Ntinginya NE, Rachow A, Hoelscher M, Cirillo DM, Skenders G, Hoffner S, Bakonyte D, Stakenas P, Diel R, Crudu V, Moldovan O, Al-Hajoj S, Otero L, Barletta F, Jane Carter E, Diero L, Supply P, Comas I, Niemann S, Gagneux S.

Nat Genet. 2016 Dec;48(12):1535-1543. doi: 10.1038/ng.3704. Epub 2016 Oct 31.


Prevalence of Nontuberculous Mycobacterial Pulmonary Disease, Germany, 2009-2014.

Ringshausen FC, Wagner D, de Roux A, Diel R, Hohmann D, Hickstein L, Welte T, Rademacher J.

Emerg Infect Dis. 2016 Jun;22(6):1102-5. doi: 10.3201/eid2206.151642.


Corrigendum: Rapid antibiotic-resistance predictions from genome sequence data for Staphylococcus aureus and Mycobacterium tuberculosis.

Bradley P, Gordon NC, Walker TM, Dunn L, Heys S, Huang B, Earle S, Pankhurst LJ, Anson L, de Cesare M, Piazza P, Votintseva AA, Golubchik T, Wilson DJ, Wyllie DH, Diel R, Niemann S, Feuerriegel S, Kohl TA, Ismail N, Omar SV, Smith EG, Buck D, McVean G, Walker AS, Peto TE, Crook DW, Iqbal Z.

Nat Commun. 2016 Apr 20;7:11465. doi: 10.1038/ncomms11465. No abstract available.


Consequences of tuberculosis among asylum seekers for health care workers in Germany.

Diel R, Loddenkemper R, Nienhaus A.

J Occup Med Toxicol. 2016 Feb 16;11:4. doi: 10.1186/s12995-016-0093-x. eCollection 2016.


[Tuberculosis and Tobacco Smoking].

Loddenkemper R, Brönnecke M, Castell S, Diel R.

Pneumologie. 2016 Jan;70(1):17-22. doi: 10.1055/s-0041-109601. Epub 2016 Jan 20. Review. German.


Rapid antibiotic-resistance predictions from genome sequence data for Staphylococcus aureus and Mycobacterium tuberculosis.

Bradley P, Gordon NC, Walker TM, Dunn L, Heys S, Huang B, Earle S, Pankhurst LJ, Anson L, de Cesare M, Piazza P, Votintseva AA, Golubchik T, Wilson DJ, Wyllie DH, Diel R, Niemann S, Feuerriegel S, Kohl TA, Ismail N, Omar SV, Smith EG, Buck D, McVean G, Walker AS, Peto TE, Crook DW, Iqbal Z.

Nat Commun. 2015 Dec 21;6:10063. doi: 10.1038/ncomms10063. Erratum in: Nat Commun. 2016;7:11465.


Cost-benefit analysis of Xpert MTB/RIF for tuberculosis suspects in German hospitals.

Diel R, Nienhaus A, Hillemann D, Richter E.

Eur Respir J. 2016 Feb;47(2):575-87. doi: 10.1183/13993003.01333-2015. Epub 2015 Dec 2.


Cost-effectiveness of incorporating bedaquiline into a treatment regimen for MDR/XDR-TB in Germany.

Wolfson LJ, Gibbert J, Wirth D, Diel R.

Eur Respir J. 2015 Dec;46(6):1826-9. doi: 10.1183/13993003.00811-2015. Epub 2015 Oct 22. No abstract available.


Bronchiectasis in Germany: a population-based estimation of disease prevalence.

Ringshausen FC, de Roux A, Diel R, Hohmann D, Welte T, Rademacher J.

Eur Respir J. 2015 Dec;46(6):1805-7. doi: 10.1183/13993003.00954-2015. Epub 2015 Aug 20. No abstract available.


Whole-genome sequencing for prediction of Mycobacterium tuberculosis drug susceptibility and resistance: a retrospective cohort study.

Walker TM, Kohl TA, Omar SV, Hedge J, Del Ojo Elias C, Bradley P, Iqbal Z, Feuerriegel S, Niehaus KE, Wilson DJ, Clifton DA, Kapatai G, Ip CLC, Bowden R, Drobniewski FA, Allix-Béguec C, Gaudin C, Parkhill J, Diel R, Supply P, Crook DW, Smith EG, Walker AS, Ismail N, Niemann S, Peto TEA; Modernizing Medical Microbiology (MMM) Informatics Group.

Lancet Infect Dis. 2015 Oct;15(10):1193-1202. doi: 10.1016/S1473-3099(15)00062-6. Epub 2015 Jun 23. Erratum in: Lancet Infect Dis. 2017 Nov 21;:.


[Current Issues Arising from Tuberculosis Screening with Interferon-Gamma-Release Assays (IGRAs)].

Diel R, Nienhaus A.

Pneumologie. 2015 May;69(5):271-5. doi: 10.1055/s-0034-1391919. Epub 2015 May 13. Review. German.


Cost effectiveness of treating multi-drug resistant tuberculosis by adding Deltyba™ to background regimens in Germany.

Diel R, Hittel N, Schaberg T.

Respir Med. 2015 May;109(5):632-41. doi: 10.1016/j.rmed.2015.01.017. Epub 2015 Feb 4.


Towards tuberculosis elimination: an action framework for low-incidence countries.

Lönnroth K, Migliori GB, Abubakar I, D'Ambrosio L, de Vries G, Diel R, Douglas P, Falzon D, Gaudreau MA, Goletti D, González Ochoa ER, LoBue P, Matteelli A, Njoo H, Solovic I, Story A, Tayeb T, van der Werf MJ, Weil D, Zellweger JP, Abdel Aziz M, Al Lawati MR, Aliberti S, Arrazola de Oñate W, Barreira D, Bhatia V, Blasi F, Bloom A, Bruchfeld J, Castelli F, Centis R, Chemtob D, Cirillo DM, Colorado A, Dadu A, Dahle UR, De Paoli L, Dias HM, Duarte R, Fattorini L, Gaga M, Getahun H, Glaziou P, Goguadze L, Del Granado M, Haas W, Järvinen A, Kwon GY, Mosca D, Nahid P, Nishikiori N, Noguer I, O'Donnell J, Pace-Asciak A, Pompa MG, Popescu GG, Robalo Cordeiro C, Rønning K, Ruhwald M, Sculier JP, Simunović A, Smith-Palmer A, Sotgiu G, Sulis G, Torres-Duque CA, Umeki K, Uplekar M, van Weezenbeek C, Vasankari T, Vitillo RJ, Voniatis C, Wanlin M, Raviglione MC.

Eur Respir J. 2015 Apr;45(4):928-52. doi: 10.1183/09031936.00214014. Review.


Cost Effectiveness of Preventive Treatment for Tuberculosis in Special High-Risk Populations.

Diel R, Lampenius N, Nienhaus A.

Pharmacoeconomics. 2015 Aug;33(8):783-809. doi: 10.1007/s40273-015-0267-x. Review.


Evolutionary history and global spread of the Mycobacterium tuberculosis Beijing lineage.

Merker M, Blin C, Mona S, Duforet-Frebourg N, Lecher S, Willery E, Blum MG, Rüsch-Gerdes S, Mokrousov I, Aleksic E, Allix-Béguec C, Antierens A, Augustynowicz-Kopeć E, Ballif M, Barletta F, Beck HP, Barry CE 3rd, Bonnet M, Borroni E, Campos-Herrero I, Cirillo D, Cox H, Crowe S, Crudu V, Diel R, Drobniewski F, Fauville-Dufaux M, Gagneux S, Ghebremichael S, Hanekom M, Hoffner S, Jiao WW, Kalon S, Kohl TA, Kontsevaya I, Lillebæk T, Maeda S, Nikolayevskyy V, Rasmussen M, Rastogi N, Samper S, Sanchez-Padilla E, Savic B, Shamputa IC, Shen A, Sng LH, Stakenas P, Toit K, Varaine F, Vukovic D, Wahl C, Warren R, Supply P, Niemann S, Wirth T.

Nat Genet. 2015 Mar;47(3):242-9. doi: 10.1038/ng.3195. Epub 2015 Jan 19.


Cost of multi drug resistance tuberculosis in Germany.

Diel R, Nienhaus A, Lampenius N, Rüsch-Gerdes S, Richter E.

Respir Med. 2014 Nov;108(11):1677-87. doi: 10.1016/j.rmed.2014.09.021. Epub 2014 Oct 15.


Costs and Effectiveness of Combination Therapy with Bedaquiline and other Anti-Tuberculosis Drugs in Patients with Multi- and Extensively Drug-Resistant Tuberculosis in Germany.

Wolfson L, Wirth D, Jibbert J, Diel R, Rutz S.

Value Health. 2014 Nov;17(7):A674-5. doi: 10.1016/j.jval.2014.08.2503. Epub 2014 Oct 26. No abstract available.

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