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Items: 1 to 50 of 70

1.

Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer.

Sahin U, Derhovanessian E, Miller M, Kloke BP, Simon P, Löwer M, Bukur V, Tadmor AD, Luxemburger U, Schrörs B, Omokoko T, Vormehr M, Albrecht C, Paruzynski A, Kuhn AN, Buck J, Heesch S, Schreeb KH, Müller F, Ortseifer I, Vogler I, Godehardt E, Attig S, Rae R, Breitkreuz A, Tolliver C, Suchan M, Martic G, Hohberger A, Sorn P, Diekmann J, Ciesla J, Waksmann O, Brück AK, Witt M, Zillgen M, Rothermel A, Kasemann B, Langer D, Bolte S, Diken M, Kreiter S, Nemecek R, Gebhardt C, Grabbe S, Höller C, Utikal J, Huber C, Loquai C, Türeci Ö.

Nature. 2017 Jul 13;547(7662):222-226. doi: 10.1038/nature23003. Epub 2017 Jul 5.

PMID:
28678784
2.

Studies on the contributions of smoke constituents, individually and in mixtures, in a range of in vitro bioactivity assays.

Stabbert R, Dempsey R, Diekmann J, Euchenhofer C, Hagemeister T, Haussmann HJ, Knorr A, Mueller BP, Pospisil P, Reininghaus W, Roemer E, Tewes FJ, Veltel DJ.

Toxicol In Vitro. 2017 Aug;42:222-246. doi: 10.1016/j.tiv.2017.04.003. Epub 2017 Apr 28.

3.

A novel clinical score (InterTAK Diagnostic Score) to differentiate takotsubo syndrome from acute coronary syndrome: results from the International Takotsubo Registry.

Ghadri JR, Cammann VL, Jurisic S, Seifert B, Napp LC, Diekmann J, Bataiosu DR, D'Ascenzo F, Ding KJ, Sarcon A, Kazemian E, Birri T, Ruschitzka F, Lüscher TF, Templin C; InterTAK co-investigators.

Eur J Heart Fail. 2017 Aug;19(8):1036-1042. doi: 10.1002/ejhf.683. Epub 2016 Dec 7.

4.

[Description of a Multidimensional Health Program for Informal Caregivers].

Hetzel C, Baumann R, Diekmann J, Froböse I.

Gesundheitswesen. 2018 Mar;80(S 02):S51-S56. doi: 10.1055/s-0042-112814. Epub 2016 Oct 18. German.

PMID:
27756085
5.

Hepatitis E in blood donors: investigation of the natural course of asymptomatic infection, Germany, 2011.

Vollmer T, Diekmann J, Eberhardt M, Knabbe C, Dreier J.

Euro Surveill. 2016 Sep 1;21(35). doi: 10.2807/1560-7917.ES.2016.21.35.30332.

6.
7.

Differences in the Clinical Profile and Outcomes of Typical and Atypical Takotsubo Syndrome: Data From the International Takotsubo Registry.

Ghadri JR, Cammann VL, Napp LC, Jurisic S, Diekmann J, Bataiosu DR, Seifert B, Jaguszewski M, Sarcon A, Neumann CA, Geyer V, Prasad A, Bax JJ, Ruschitzka F, Lüscher TF, Templin C; International Takotsubo (InterTAK) Registry.

JAMA Cardiol. 2016 Jun 1;1(3):335-40. doi: 10.1001/jamacardio.2016.0225.

8.

Safety and efficacy profile of bioresorbable-polylactide-polymer-biolimus-A9-eluting stents versus durable-polymer-everolimus- and zotarolimus-eluting stents in patients with acute coronary syndrome.

Jaguszewski M, Dörig M, Frangieh AH, Ghadri JR, Cammann VL, Diekmann J, Napp LC, D'Ascenzo F, Imori Y, Obeid S, Maier W, Lüscher TF, Templin C.

Catheter Cardiovasc Interv. 2016 Nov 15;88(6):E173-E182. doi: 10.1002/ccd.26617. Epub 2016 Jul 5.

PMID:
27377554
9.

[Homozygous hypercholesterolemia - new therapeutic options in cases with complete lack of LDL- receptor].

Mellwig KP, Farr M, Diekmann J, Horstkotte D, van Buuren F.

Dtsch Med Wochenschr. 2016 Jun;141(12):878-81. doi: 10.1055/s-0041-109013. Epub 2016 Jun 15. German.

PMID:
27305304
10.

Systemic RNA delivery to dendritic cells exploits antiviral defence for cancer immunotherapy.

Kranz LM, Diken M, Haas H, Kreiter S, Loquai C, Reuter KC, Meng M, Fritz D, Vascotto F, Hefesha H, Grunwitz C, Vormehr M, Hüsemann Y, Selmi A, Kuhn AN, Buck J, Derhovanessian E, Rae R, Attig S, Diekmann J, Jabulowsky RA, Heesch S, Hassel J, Langguth P, Grabbe S, Huber C, Türeci Ö, Sahin U.

Nature. 2016 Jun 16;534(7607):396-401. doi: 10.1038/nature18300. Epub 2016 Jun 1.

PMID:
27281205
11.

Happy heart syndrome: role of positive emotional stress in takotsubo syndrome.

Ghadri JR, Sarcon A, Diekmann J, Bataiosu DR, Cammann VL, Jurisic S, Napp LC, Jaguszewski M, Scherff F, Brugger P, Jäncke L, Seifert B, Bax JJ, Ruschitzka F, Lüscher TF, Templin C; InterTAK Co-investigators:.

Eur Heart J. 2016 Oct 1;37(37):2823-2829. Epub 2016 Mar 2.

12.

Heterocyclic aromatic amines and their contribution to the bacterial mutagenicity of the particulate phase of cigarette smoke.

Roemer E, Meisgen T, Diekmann J, Conroy L, Stabbert R.

Toxicol Lett. 2016 Jan 22;243:40-7. doi: 10.1016/j.toxlet.2015.12.008. Epub 2015 Dec 24.

13.

Examination of a biodegradable magnesium screw for the reconstruction of the anterior cruciate ligament: A pilot in vivo study in rabbits.

Diekmann J, Bauer S, Weizbauer A, Willbold E, Windhagen H, Helmecke P, Lucas A, Reifenrath J, Nolte I, Ezechieli M.

Mater Sci Eng C Mater Biol Appl. 2016 Feb;59:1100-1109. doi: 10.1016/j.msec.2015.11.037. Epub 2015 Nov 14.

PMID:
26652469
14.

A three-dimensional skin equivalent reflecting some aspects of in vivo aged skin.

Diekmann J, Alili L, Scholz O, Giesen M, Holtkötter O, Brenneisen P.

Exp Dermatol. 2016 Jan;25(1):56-61. doi: 10.1111/exd.12866. Epub 2015 Nov 23.

PMID:
26440058
15.

First N-Heterocyclic Carbenes Relying on the Triazolone Structural Motif: Syntheses, Modifications and Reactivity.

Jonek M, Diekmann J, Ganter C.

Chemistry. 2015 Oct 26;21(44):15759-68. doi: 10.1002/chem.201502685. Epub 2015 Sep 23.

PMID:
26395132
16.

Clinical Features and Outcomes of Takotsubo (Stress) Cardiomyopathy.

Templin C, Ghadri JR, Diekmann J, Napp LC, Bataiosu DR, Jaguszewski M, Cammann VL, Sarcon A, Geyer V, Neumann CA, Seifert B, Hellermann J, Schwyzer M, Eisenhardt K, Jenewein J, Franke J, Katus HA, Burgdorf C, Schunkert H, Moeller C, Thiele H, Bauersachs J, Tschöpe C, Schultheiss HP, Laney CA, Rajan L, Michels G, Pfister R, Ukena C, Böhm M, Erbel R, Cuneo A, Kuck KH, Jacobshagen C, Hasenfuss G, Karakas M, Koenig W, Rottbauer W, Said SM, Braun-Dullaeus RC, Cuculi F, Banning A, Fischer TA, Vasankari T, Airaksinen KE, Fijalkowski M, Rynkiewicz A, Pawlak M, Opolski G, Dworakowski R, MacCarthy P, Kaiser C, Osswald S, Galiuto L, Crea F, Dichtl W, Franz WM, Empen K, Felix SB, Delmas C, Lairez O, Erne P, Bax JJ, Ford I, Ruschitzka F, Prasad A, Lüscher TF.

N Engl J Med. 2015 Sep 3;373(10):929-38. doi: 10.1056/NEJMoa1406761.

17.

Transfusion of 1 and 2 units of red blood cells does not increase mortality and organ failure in patients undergoing isolated coronary artery bypass grafting.

Koster A, Zittermann A, Börgermann J, Knabbe C, Diekmann J, Schirmer U, Gummert JF.

Eur J Cardiothorac Surg. 2016 Mar;49(3):931-6. doi: 10.1093/ejcts/ezv252. Epub 2015 Jul 22.

PMID:
26201957
18.

Erratum: Mutant MHC class II epitopes drive therapeutic immune responses to cancer.

Kreiter S, Vormehr M, van de Roemer N, Diken M, Löwer M, Diekmann J, Boegel S, Schrörs B, Vascotto F, Castle JC, Tadmor AD, Schoenberger SP, Huber C, Türeci Ö, Sahin U.

Nature. 2015 Jul 16;523(7560):370. doi: 10.1038/nature14567. Epub 2015 Jun 3. No abstract available.

PMID:
26040715
19.

Magnesium-containing layered double hydroxides as orthopaedic implant coating materials--An in vitro and in vivo study.

Weizbauer A, Kieke M, Rahim MI, Angrisani GL, Willbold E, Diekmann J, Flörkemeier T, Windhagen H, Müller PP, Behrens P, Budde S.

J Biomed Mater Res B Appl Biomater. 2016 Apr;104(3):525-31. doi: 10.1002/jbm.b.33422. Epub 2015 May 1.

PMID:
25939995
20.

Mutant MHC class II epitopes drive therapeutic immune responses to cancer.

Kreiter S, Vormehr M, van de Roemer N, Diken M, Löwer M, Diekmann J, Boegel S, Schrörs B, Vascotto F, Castle JC, Tadmor AD, Schoenberger SP, Huber C, Türeci Ö, Sahin U.

Nature. 2015 Apr 30;520(7549):692-6. doi: 10.1038/nature14426. Epub 2015 Apr 22. Erratum in: Nature. 2015 Jul 16;523(7560):370.

21.

Serological evidence of increased susceptibility to varicella-zoster virus reactivation or reinfection in natalizumab-treated patients with multiple sclerosis.

Kohlmann R, Salmen A, Chan A, Knabbe C, Diekmann J, Brockmeyer N, Skaletz-Rorowski A, Michalik C, Gold R, Überla K.

Mult Scler. 2015 Dec;21(14):1823-32. doi: 10.1177/1352458515576984. Epub 2015 Mar 31.

PMID:
25828755
22.

Gender disparities in acute coronary syndrome: a closing gap in the short-term outcome.

Ghadri JR, Sarcon A, Jaguszewski M, Diekmann J, Bataiosu RD, Hellermann J, Csordas A, Baumann L, Schöni AA, Lüscher TF, Templin C.

J Cardiovasc Med (Hagerstown). 2015 May;16(5):355-62. doi: 10.2459/JCM.0000000000000248.

23.

Translation of genomics-guided RNA-based personalised cancer vaccines: towards the bedside.

Boisguérin V, Castle JC, Loewer M, Diekmann J, Mueller F, Britten CM, Kreiter S, Türeci Ö, Sahin U.

Br J Cancer. 2014 Oct 14;111(8):1469-75. doi: 10.1038/bjc.2013.820. Review.

24.

Feasibility of second-generation bioresorbable vascular scaffold implantation in complex anatomical and clinical scenarios.

Jaguszewski M, Ghadri JR, Zipponi M, Bataiosu DR, Diekmann J, Geyer V, Neumann CA, Huber MA, Hagl C, Erne P, Lüscher TF, Templin C.

Clin Res Cardiol. 2015 Feb;104(2):124-35. doi: 10.1007/s00392-014-0757-4. Epub 2014 Aug 31.

25.

Acute coronary syndromes in octogenarians referred for invasive evaluation: treatment profile and outcomes.

Jaguszewski M, Ghadri JR, Diekmann J, Bataiosu RD, Hellermann JP, Sarcon A, Siddique A, Baumann L, Stähli BE, Lüscher TF, Maier W, Templin C.

Clin Res Cardiol. 2015 Jan;104(1):51-8. doi: 10.1007/s00392-014-0756-5. Epub 2014 Aug 21.

PMID:
25142902
26.

A vaccine targeting mutant IDH1 induces antitumour immunity.

Schumacher T, Bunse L, Pusch S, Sahm F, Wiestler B, Quandt J, Menn O, Osswald M, Oezen I, Ott M, Keil M, Balß J, Rauschenbach K, Grabowska AK, Vogler I, Diekmann J, Trautwein N, Eichmüller SB, Okun J, Stevanović S, Riemer AB, Sahin U, Friese MA, Beckhove P, von Deimling A, Wick W, Platten M.

Nature. 2014 Aug 21;512(7514):324-7. doi: 10.1038/nature13387. Epub 2014 Jun 25.

PMID:
25043048
27.

A drug-induced accelerated senescence (DIAS) is a possibility to study aging in time lapse.

Alili L, Diekmann J, Giesen M, Holtkötter O, Brenneisen P.

Age (Dordr). 2014 Jun;36(3):9658. doi: 10.1007/s11357-014-9658-8. Epub 2014 May 16.

28.

mTOR inhibition improves antitumor effects of vaccination with antigen-encoding RNA.

Diken M, Kreiter S, Vascotto F, Selmi A, Attig S, Diekmann J, Huber C, Türeci Ö, Sahin U.

Cancer Immunol Res. 2013 Dec;1(6):386-92. doi: 10.1158/2326-6066.CIR-13-0046. Epub 2013 Sep 20.

29.

First case of atypical takotsubo cardiomyopathy in a bilateral lung-transplanted patient due to acute respiratory failure.

Ghadri JR, Bataisou RD, Diekmann J, Lüscher TF, Templin C.

Eur Heart J Acute Cardiovasc Care. 2015 Oct;4(5):482-5. doi: 10.1177/2048872614527836. Epub 2014 Mar 13.

PMID:
24627332
30.

Biodegradation of a magnesium alloy implant in the intercondylar femoral notch showed an appropriate response to the synovial membrane in a rabbit model in vivo.

Ezechieli M, Diekmann J, Weizbauer A, Becher C, Willbold E, Helmecke P, Lucas A, Schavan R, Windhagen H.

J Biomater Appl. 2014 Aug;29(2):291-302. Epub 2014 Feb 12.

PMID:
24522242
31.

Evaluating a Novel Class of Biomaterials: Magnesium-Containing Layered Double Hydroxides.

Kieke MD, Weizbauer A, Duda F, Badar M, Budde S, Flörkemeier T, Diekmann J, Prenzler N, Rahim MI, Müller PP, Hauser H, Behrens S, Dellinger P, Möhwald K, Lenarz T, Windhagen H, Behrens P.

Biomed Tech (Berl). 2013 Sep 7. pii: /j/bmte.2013.58.issue-s1-C/bmt-2013-4072/bmt-2013-4072.xml. doi: 10.1515/bmt-2013-4072. [Epub ahead of print] No abstract available.

PMID:
24042648
32.

Biodegradable magnesium-based screw clinically equivalent to titanium screw in hallux valgus surgery: short term results of the first prospective, randomized, controlled clinical pilot study.

Windhagen H, Radtke K, Weizbauer A, Diekmann J, Noll Y, Kreimeyer U, Schavan R, Stukenborg-Colsman C, Waizy H.

Biomed Eng Online. 2013 Jul 3;12:62. doi: 10.1186/1475-925X-12-62.

33.

Fulminate heparin-induced thrombocytopenia and surgery with deep hypothermic circulatory arrest using bivalirudin.

Koster A, Amin-Parsa M, Kaufmann M, Meyer-Jark T, Rudloff M, Diekmann J, Georg WM, Liebke M, Schirmer U, Gummert JF.

Ann Thorac Surg. 2013 Mar;95(3):1079-81. doi: 10.1016/j.athoracsur.2012.07.072.

PMID:
23438537
34.

In vivo study of a biodegradable orthopedic screw (MgYREZr-alloy) in a rabbit model for up to 12 months.

Waizy H, Diekmann J, Weizbauer A, Reifenrath J, Bartsch I, Neubert V, Schavan R, Windhagen H.

J Biomater Appl. 2014 Jan;28(5):667-75. doi: 10.1177/0885328212472215. Epub 2013 Jan 3.

PMID:
23292720
35.

Reduced exposure evaluation of an Electrically Heated Cigarette Smoking System. Part 2: Smoke chemistry and in vitro toxicological evaluation using smoking regimens reflecting human puffing behavior.

Zenzen V, Diekmann J, Gerstenberg B, Weber S, Wittke S, Schorp MK.

Regul Toxicol Pharmacol. 2012 Nov 1;64(2 Suppl):S11-34. doi: 10.1016/j.yrtph.2012.08.004. Epub 2012 Aug 23. Erratum in: Regul Toxicol Pharmacol. 2015 Mar;71(2):184.

36.

Novel approach for detection of hepatitis E virus infection in German blood donors.

Vollmer T, Diekmann J, Johne R, Eberhardt M, Knabbe C, Dreier J.

J Clin Microbiol. 2012 Aug;50(8):2708-13. doi: 10.1128/JCM.01119-12. Epub 2012 Jun 6.

37.

Exploiting the mutanome for tumor vaccination.

Castle JC, Kreiter S, Diekmann J, Löwer M, van de Roemer N, de Graaf J, Selmi A, Diken M, Boegel S, Paret C, Koslowski M, Kuhn AN, Britten CM, Huber C, Türeci O, Sahin U.

Cancer Res. 2012 Mar 1;72(5):1081-91. doi: 10.1158/0008-5472.CAN-11-3722. Epub 2012 Jan 11.

38.

FLT3 ligand enhances the cancer therapeutic potency of naked RNA vaccines.

Kreiter S, Diken M, Selmi A, Diekmann J, Attig S, Hüsemann Y, Koslowski M, Huber C, Türeci Ö, Sahin U.

Cancer Res. 2011 Oct 1;71(19):6132-42. doi: 10.1158/0008-5472.CAN-11-0291. Epub 2011 Aug 4.

39.

Portable microcoil NMR detection coupled to capillary electrophoresis.

Diekmann J, Adams KL, Klunder GL, Evans L, Steele P, Vogt C, Herberg JL.

Anal Chem. 2011 Feb 15;83(4):1328-35. doi: 10.1021/ac102389b. Epub 2011 Jan 14.

PMID:
21235258
40.

Processing of two latent membrane protein 1 MHC class I epitopes requires tripeptidyl peptidase II involvement.

Diekmann J, Adamopoulou E, Beck O, Rauser G, Lurati S, Tenzer S, Einsele H, Rammensee HG, Schild H, Topp MS.

J Immunol. 2009 Aug 1;183(3):1587-97. doi: 10.4049/jimmunol.0803441. Epub 2009 Jul 8.

41.

Effect of filtration by activated charcoal on the toxicological activity of cigarette mainstream smoke from experimental cigarettes.

Gaworski CL, Schramke H, Diekmann J, Meisgen TJ, Tewes FJ, Veltel DJ, Vanscheeuwijck PM, Rajendran N, Muzzio M, Haussmann HJ.

Inhal Toxicol. 2009 Jul;21(8):688-704. doi: 10.1080/08958370802406290.

PMID:
19555222
42.

Autologous blood donor screening indicated a lower prevalence of viral hepatitis in East vs West Germany: epidemiological benefit from established health resources.

Wiegand J, Luz B, Mengelkamp AK, Moog R, Koscielny J, Halm-Heinrich I, Susemihl C, Bentzien F, Diekmann J, Wernet D, Karger R, Angert K, Schmitt-Thomssen A, Kiefel V, Lutter K, Hesse R, Kätzel R, Opitz A, Luhm J, Barz D, Leib U, Matthes G, Tillmann HL.

J Viral Hepat. 2009 Oct;16(10):743-8. doi: 10.1111/j.1365-2893.2009.01132.x. Epub 2009 May 26.

PMID:
19486277
43.

Stratification for noninvasive coronary angiography: patient preselection considering atypical angina pectoris, conventional cardiovascular risk assessment, and calcium scoring.

Langer C, Wiemer M, Peterschröder A, Franzke K, Mellwig KP, van Buuren F, Koester-Eiserfunke W, Butz T, Diekmann J, Horstkotte D.

Eur J Cardiovasc Prev Rehabil. 2009 Apr;16(2):201-9. doi: 10.1097/HJR.0b013e32832776de.

PMID:
19305353
44.
45.

Human CD4+ T cells displaying viral epitopes elicit a functional virus-specific memory CD8+ T cell response.

Adamopoulou E, Diekmann J, Tolosa E, Kuntz G, Einsele H, Rammensee HG, Topp MS.

J Immunol. 2007 May 1;178(9):5465-72.

46.

Involvement of semiquinone radicals in the in vitro cytotoxicity of cigarette mainstream smoke.

Chouchane S, Wooten JB, Tewes FJ, Wittig A, Müller BP, Veltel D, Diekmann J.

Chem Res Toxicol. 2006 Dec;19(12):1602-10.

PMID:
17173373
47.
48.

Removing the threat of diclofenac to critically endangered Asian vultures.

Swan G, Naidoo V, Cuthbert R, Green RE, Pain DJ, Swarup D, Prakash V, Taggart M, Bekker L, Das D, Diekmann J, Diekmann M, Killian E, Meharg A, Patra RC, Saini M, Wolter K.

PLoS Biol. 2006 Mar;4(3):e66. Epub 2006 Jan 31.

49.

Hormonal counterregulation during severe hypoglycaemia under everyday conditions in patients with type 1 and insulin-treated type 2 diabetes mellitus.

Holstein A, Hammer C, Plaschke A, Ptak M, Kuhn J, Diekmann J, Kleesiek K, Egberts EH.

Exp Clin Endocrinol Diabetes. 2004 Sep;112(8):429-34.

PMID:
15372362
50.

Low-level viraemia of hepatitis B virus in an anti-HBc- and anti-HBs-positive blood donor.

Dreier J, Kröger M, Diekmann J, Götting C, Kleesiek K.

Transfus Med. 2004 Apr;14(2):97-103.

PMID:
15113374

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