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Cellular redox state constrains serine synthesis and nucleotide production to impact cell proliferation.

Diehl FF, Lewis CA, Fiske BP, Vander Heiden MG.

Nat Metab. 2019 Sep;1(9):861-867. doi: 10.1038/s42255-019-0108-x. Epub 2019 Sep 16.


[Nosocomial urinary tract infection: an analysis beyond urinary catheterization].

Baenas DF, Saad EJ, Diehl FA, Musso D, González JG, Russo V, Vilaró M, Albertini RA.

Rev Chilena Infectol. 2018;35(3):246-252. doi: 10.4067/s0716-10182018000300246. Spanish.


PIB: A Score to Select Sorafenib Treatment Candidates for Hepatocellular Carcinoma in Resource-Limited Settings.

Leathers JS, Balderramo D, Prieto J, Diehl F, Gonzalez-Ballerga E, Ferreiro MR, Carrera E, Barreyro F, Diaz-Ferrer J, Singh D, Mattos AZ, Carrilho F, Debes JD.

Hepat Mon. 2018 Oct;18(10). pii: e82345. doi: 10.5812/hepatmon.82345. Epub 2018 Oct 21. No abstract available.


Repeated mutKRAS ctDNA measurements represent a novel and promising tool for early response prediction and therapy monitoring in advanced pancreatic cancer.

Kruger S, Heinemann V, Ross C, Diehl F, Nagel D, Ormanns S, Liebmann S, Prinz-Bravin I, Westphalen CB, Haas M, Jung A, Kirchner T, von Bergwelt-Baildon M, Boeck S, Holdenrieder S.

Ann Oncol. 2018 Dec 1;29(12):2348-2355. doi: 10.1093/annonc/mdy417.


Modulation of CrbS-Dependent Activation of the Acetate Switch in Vibrio cholerae.

Muzhingi I, Prado C, Sylla M, Diehl FF, Nguyen DK, Servos MM, Flores Ramos S, Purdy AE.

J Bacteriol. 2018 Nov 6;200(23). pii: e00380-18. doi: 10.1128/JB.00380-18. Print 2018 Dec 1.


Serine Synthesis via PHGDH Is Essential for Heme Production in Endothelial Cells.

Vandekeere S, Dubois C, Kalucka J, Sullivan MR, García-Caballero M, Goveia J, Chen R, Diehl FF, Bar-Lev L, Souffreau J, Pircher A, Kumar S, Vinckier S, Hirabayashi Y, Furuya S, Schoonjans L, Eelen G, Ghesquière B, Keshet E, Li X, Vander Heiden MG, Dewerchin M, Carmeliet P.

Cell Metab. 2018 Oct 2;28(4):573-587.e13. doi: 10.1016/j.cmet.2018.06.009. Epub 2018 Jul 12.


Sorafenib for Treatment of Hepatocellular Carcinoma: A Survival Analysis From the South American Liver Research Network.

Leathers JS, Balderramo D, Prieto J, Diehl F, Gonzalez-Ballerga E, Ferreiro MR, Carrera E, Barreyro F, Diaz-Ferrer J, Singh D, Mattos AZ, Carrilho F, Debes JD.

J Clin Gastroenterol. 2019 Jul;53(6):464-469. doi: 10.1097/MCG.0000000000001085.


Aspartate is an endogenous metabolic limitation for tumour growth.

Sullivan LB, Luengo A, Danai LV, Bush LN, Diehl FF, Hosios AM, Lau AN, Elmiligy S, Malstrom S, Lewis CA, Vander Heiden MG.

Nat Cell Biol. 2018 Jul;20(7):782-788. doi: 10.1038/s41556-018-0125-0. Epub 2018 Jun 25.


Hepatitis E virus infection in hemodialysis patients: A prospective analysis.

Pisano MB, Leathers J, Balderramo DC, Diehl F, Bolomo A, Fernández P, Martínez-Wassaf M, Cristani C, Di Cola G, De la Fuente J, Debes JD, E Ré V.

Semin Dial. 2018 Sep;31(5):528-529. doi: 10.1111/sdi.12722. Epub 2018 Jun 12. No abstract available.


Derivation and validation of a preoperative risk model for postoperative mortality (SAMPE model): An approach to care stratification.

Stefani LC, Gutierrez CS, Castro SMJ, Zimmer RL, Diehl FP, Meyer LE, Caumo W.

PLoS One. 2017 Oct 30;12(10):e0187122. doi: 10.1371/journal.pone.0187122. eCollection 2017.


1-week versus 2-week interval for endoscopic eradication of esophageal varices.

Diehl F, Balderramo D.

Dig Liver Dis. 2017 Feb;49(2):230-231. doi: 10.1016/j.dld.2016.12.017. Epub 2016 Dec 21. No abstract available.


Performance of Streck cfDNA Blood Collection Tubes for Liquid Biopsy Testing.

Medina Diaz I, Nocon A, Mehnert DH, Fredebohm J, Diehl F, Holtrup F.

PLoS One. 2016 Nov 10;11(11):e0166354. doi: 10.1371/journal.pone.0166354. eCollection 2016.


Academia Meets Industry.

Schäfer C, Paprotka T, Heitzer E, Eccleston M, Noe J, Holdenrieder S, Diehl F, Thierry A.

Adv Exp Med Biol. 2016;924:201-215.


Detection and Quantification of KIT Mutations in ctDNA by Plasma Safe-SeqS.

Fredebohm J, Mehnert DH, Löber AK, Holtrup F, van Rahden V, Angenendt P, Diehl F.

Adv Exp Med Biol. 2016;924:187-189.


Kikuchi-Fujimoto disease and systemic lupus erythematosus.

Baenas DF, Diehl FA, Haye Salinas MJ, Riva V, Diller A, Lemos PA.

Int Med Case Rep J. 2016 Jun 29;9:163-7. doi: 10.2147/IMCRJ.S106396. eCollection 2016.


Behavioral alterations induced by repeated saxitoxin exposure in drinking water.

Diehl F, Ramos PB, Dos Santos JM, Barros DM, Yunes JS.

J Venom Anim Toxins Incl Trop Dis. 2016 May 17;22:18. doi: 10.1186/s40409-016-0072-9. eCollection 2016.


Novel learning accelerates systems consolidation of a contextual fear memory.

Haubrich J, Cassini LF, Diehl F, Santana F, Fürstenau de Oliveira L, de Oliveira Alvares L, Quillfeldt JA.

Hippocampus. 2016 Jul;26(7):924-32. doi: 10.1002/hipo.22575. Epub 2016 Mar 11.


Erratum: Actionable mutations in plasma cell-free DNA in patients with advanced cancers referred for experimental targeted therapies.

Janku F, Angenendt P, Tsimberidou AM, Fu S, Naing A, Falchook GS, Hong DS, Holley VR, Cabrilo G, Wheler JJ, Piha-Paul SA, Zinner RG, Bedikian AY, Overman MJ, Kee BK, Kim KB, Kopetz ES, Luthra R, Diehl F, Meric-Bernstam F, Kurzrock R.

Oncotarget. 2015 Sep 15;6(27):24581.


Actionable mutations in plasma cell-free DNA in patients with advanced cancers referred for experimental targeted therapies.

Janku F, Angenendt P, Tsimberidou AM, Fu S, Naing A, Falchook GS, Hong DS, Holley VR, Cabrilo G, Wheler JJ, Piha-Paul SA, Zinner RG, Bedikian AY, Overman MJ, Kee BK, Kim KB, Kopetz ES, Luthra R, Diehl F, Meric-Bernstam F, Kurzrock R.

Oncotarget. 2015 May 20;6(14):12809-21. Erratum in: Oncotarget. 2015 Sep 15;6(27):24581.


Characterizing the patterns of clonal selection in circulating tumor DNA from patients with colorectal cancer refractory to anti-EGFR treatment.

Morelli MP, Overman MJ, Dasari A, Kazmi SM, Mazard T, Vilar E, Morris VK, Lee MS, Herron D, Eng C, Morris J, Kee BK, Janku F, Deaton FL, Garrett C, Maru D, Diehl F, Angenendt P, Kopetz S.

Ann Oncol. 2015 Apr;26(4):731-6. doi: 10.1093/annonc/mdv005. Epub 2015 Jan 26.


Sec24 is a coincidence detector that simultaneously binds two signals to drive ER export.

Pagant S, Wu A, Edwards S, Diehl F, Miller EA.

Curr Biol. 2015 Feb 16;25(4):403-12. doi: 10.1016/j.cub.2014.11.070. Epub 2015 Jan 22.


Multiple and antagonistic effects of water on intrinsic physical properties of model Fischer-Tropsch cobalt catalysts evidenced by in situ X-ray diffraction.

Scalbert J, Legens C, Clémençon I, Taleb AL, Sorbier L, Diehl F.

Chem Commun (Camb). 2014 Jul 25;50(58):7866-9. doi: 10.1039/c4cc00947a.


Emergence of Coherence through Variation of Intermolecular Distances in a Series of Molecular Dimers.

Diehl FP, Roos C, Duymaz A, Lunkenheimer B, Köhn A, Basché T.

J Phys Chem Lett. 2014 Jan 16;5(2):262-9. doi: 10.1021/jz402512g. Epub 2013 Dec 26.


Motor circuit-specific burst patterns drive different muscle and behavior patterns.

Diehl F, White RS, Stein W, Nusbaum MP.

J Neurosci. 2013 Jul 17;33(29):12013-29. doi: 10.1523/JNEUROSCI.1060-13.2013.


Combined targeting of AKT and mTOR using MK-2206 and RAD001 is synergistic in the treatment of cholangiocarcinoma.

Ewald F, Grabinski N, Grottke A, Windhorst S, Nörz D, Carstensen L, Staufer K, Hofmann BT, Diehl F, David K, Schumacher U, Nashan B, Jücker M.

Int J Cancer. 2013 Nov;133(9):2065-76. doi: 10.1002/ijc.28214. Epub 2013 May 29.


The stomatogastric nervous system as a model for studying sensorimotor interactions in real-time closed-loop conditions.

Daur N, Diehl F, Mader W, Stein W.

Front Comput Neurosci. 2012 Mar 14;6:13. doi: 10.3389/fncom.2012.00013. eCollection 2012.


Detection of tumor PIK3CA status in metastatic breast cancer using peripheral blood.

Higgins MJ, Jelovac D, Barnathan E, Blair B, Slater S, Powers P, Zorzi J, Jeter SC, Oliver GR, Fetting J, Emens L, Riley C, Stearns V, Diehl F, Angenendt P, Huang P, Cope L, Argani P, Murphy KM, Bachman KE, Greshock J, Wolff AC, Park BH.

Clin Cancer Res. 2012 Jun 15;18(12):3462-9. doi: 10.1158/1078-0432.CCR-11-2696. Epub 2012 Mar 15.


Nephronectin regulates atrioventricular canal differentiation via Bmp4-Has2 signaling in zebrafish.

Patra C, Diehl F, Ferrazzi F, van Amerongen MJ, Novoyatleva T, Schaefer L, Mühlfeld C, Jungblut B, Engel FB.

Development. 2011 Oct;138(20):4499-509. doi: 10.1242/dev.067454.


β-Cyclodextrin for design of alumina supported cobalt catalysts efficient in Fischer-Tropsch synthesis.

Jean-Marie A, Griboval-Constant A, Khodakov AY, Monflier E, Diehl F.

Chem Commun (Camb). 2011 Oct 14;47(38):10767-9. doi: 10.1039/c1cc13800f. Epub 2011 Aug 26.


Detection of tumor DNA at the margins of colorectal cancer liver metastasis.

Holdhoff M, Schmidt K, Diehl F, Aggrawal N, Angenendt P, Romans K, Edelstein DL, Torbenson M, Kinzler KW, Vogelstein B, Choti MA, Diaz LA Jr.

Clin Cancer Res. 2011 Jun 1;17(11):3551-7. doi: 10.1158/1078-0432.CCR-10-3087. Epub 2011 Apr 29.


Gastric and pyloric motor pattern control by a modulatory projection neuron in the intact crab Cancer pagurus.

Hedrich UB, Diehl F, Stein W.

J Neurophysiol. 2011 Apr;105(4):1671-80. doi: 10.1152/jn.01105.2010. Epub 2011 Feb 16.


[Clinical and epidemiological profile of HIV-infected pregnant women in a service in south Brazil].

Konopka CK, Beck ST, Wiggers D, da Silva AK, Diehl FP, Santos FG.

Rev Bras Ginecol Obstet. 2010 Apr;32(4):184-90. Portuguese.


Development of personalized tumor biomarkers using massively parallel sequencing.

Leary RJ, Kinde I, Diehl F, Schmidt K, Clouser C, Duncan C, Antipova A, Lee C, McKernan K, De La Vega FM, Kinzler KW, Vogelstein B, Diaz LA Jr, Velculescu VE.

Sci Transl Med. 2010 Feb 24;2(20):20ra14. doi: 10.1126/scitranslmed.3000702.


Stress response recruits the hippocampal endocannabinoid system for the modulation of fear memory.

de Oliveira Alvares L, Engelke DS, Diehl F, Scheffer-Teixeira R, Haubrich J, de Freitas Cassini L, Molina VA, Quillfeldt JA.

Learn Mem. 2010 Mar 26;17(4):202-9. doi: 10.1101/lm.1721010. Print 2010 Apr.


Cardiac deletion of Smyd2 is dispensable for mouse heart development.

Diehl F, Brown MA, van Amerongen MJ, Novoyatleva T, Wietelmann A, Harriss J, Ferrazzi F, Böttger T, Harvey RP, Tucker PW, Engel FB.

PLoS One. 2010 Mar 17;5(3):e9748. doi: 10.1371/journal.pone.0009748.


Combined experimental and theoretical study of the vibronic spectra of perylenecarboximides.

Diehl FP, Roos C, Jankowiak HC, Berger R, Köhn A, Diezemann G, Basché T.

J Phys Chem B. 2010 Feb 4;114(4):1638-47. doi: 10.1021/jp909862x.


E2F4 is required for cardiomyocyte proliferation.

van Amerongen MJ, Diehl F, Novoyatleva T, Patra C, Engel FB.

Cardiovasc Res. 2010 Apr 1;86(1):92-102. doi: 10.1093/cvr/cvp383. Epub 2009 Dec 2.


TWEAK is a positive regulator of cardiomyocyte proliferation.

Novoyatleva T, Diehl F, van Amerongen MJ, Patra C, Ferrazzi F, Bellazzi R, Engel FB.

Cardiovasc Res. 2010 Mar 1;85(4):681-90. doi: 10.1093/cvr/cvp360. Epub 2009 Nov 2.


Sensitive digital quantification of DNA methylation in clinical samples.

Li M, Chen WD, Papadopoulos N, Goodman SN, Bjerregaard NC, Laurberg S, Levin B, Juhl H, Arber N, Moinova H, Durkee K, Schmidt K, He Y, Diehl F, Velculescu VE, Zhou S, Diaz LA Jr, Kinzler KW, Markowitz SD, Vogelstein B.

Nat Biotechnol. 2009 Sep;27(9):858-63. doi: 10.1038/nbt.1559. Epub 2009 Aug 16.


HDAC5 is a repressor of angiogenesis and determines the angiogenic gene expression pattern of endothelial cells.

Urbich C, Rössig L, Kaluza D, Potente M, Boeckel JN, Knau A, Diehl F, Geng JG, Hofmann WK, Zeiher AM, Dimmeler S.

Blood. 2009 May 28;113(22):5669-79. doi: 10.1182/blood-2009-01-196485. Epub 2009 Apr 7.


Circulating mutant DNA to assess tumor dynamics.

Diehl F, Schmidt K, Choti MA, Romans K, Goodman S, Li M, Thornton K, Agrawal N, Sokoll L, Szabo SA, Kinzler KW, Vogelstein B, Diaz LA Jr.

Nat Med. 2008 Sep;14(9):985-90. doi: 10.1038/nm.1789. Epub 2007 Jul 31.


Analysis of mutations in DNA isolated from plasma and stool of colorectal cancer patients.

Diehl F, Schmidt K, Durkee KH, Moore KJ, Goodman SN, Shuber AP, Kinzler KW, Vogelstein B.

Gastroenterology. 2008 Aug;135(2):489-98. doi: 10.1053/j.gastro.2008.05.039. Epub 2008 May 15.


Opposite action of hippocampal CB1 receptors in memory reconsolidation and extinction.

de Oliveira Alvares L, Pasqualini Genro B, Diehl F, Molina VA, Quillfeldt JA.

Neuroscience. 2008 Jul 17;154(4):1648-55. doi: 10.1016/j.neuroscience.2008.05.005. Epub 2008 May 10.


Genetic proof-of-concept for cardiac gene expression in human circulating blood-derived progenitor cells.

Rupp S, Koyanagi M, Iwasaki M, Diehl F, Bushoven P, Schranz D, Zeiher AM, Dimmeler S.

J Am Coll Cardiol. 2008 Jun 10;51(23):2289-90. doi: 10.1016/j.jacc.2008.01.062. No abstract available.


Differential role of the hippocampal endocannabinoid system in the memory consolidation and retrieval mechanisms.

De Oliveira Alvares L, Genro BP, Diehl F, Quillfeldt JA.

Neurobiol Learn Mem. 2008 Jul;90(1):1-9. doi: 10.1016/j.nlm.2008.01.009. Epub 2008 Mar 14.


Comparative lesion sequencing provides insights into tumor evolution.

Jones S, Chen WD, Parmigiani G, Diehl F, Beerenwinkel N, Antal T, Traulsen A, Nowak MA, Siegel C, Velculescu VE, Kinzler KW, Vogelstein B, Willis J, Markowitz SD.

Proc Natl Acad Sci U S A. 2008 Mar 18;105(11):4283-8. doi: 10.1073/pnas.0712345105. Epub 2008 Mar 12.


[Experiences with certification of practices].

Asmuth J, Diel F, Thoma E.

Chirurg. 2007 Jul;Suppl:229-30. German. No abstract available. Erratum in: Chirurg. 2007 Sep;Suppl:294. Diehl, F [corrected to Diel, F].


Serial assessment of human tumor burdens in mice by the analysis of circulating DNA.

Rago C, Huso DL, Diehl F, Karim B, Liu G, Papadopoulos N, Samuels Y, Velculescu VE, Vogelstein B, Kinzler KW, Diaz LA Jr.

Cancer Res. 2007 Oct 1;67(19):9364-70.


A blood-based DNA test for colorectal cancer screening.

Schmidt K, Diehl F.

Discov Med. 2007 Feb;7(37):7-12.


Facilitatory effect of the intra-hippocampal pre-test administration of MT3 in the inhibitory avoidance task.

Diehl F, Fürstenau de Oliveira L, Sánchez G, Camboim C, de Oliveira Alvares L, Lanziotti VB, Cerveñansky C, Kornisiuk E, Jerusalinky D, Quillfeldt JA.

Behav Brain Res. 2007 Feb 27;177(2):227-31. Epub 2006 Dec 19.


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