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Items: 1 to 50 of 709

1.

The Natural History of Advanced Fibrosis Due to Nonalcoholic Steatohepatitis: Data From the Simtuzumab Trials.

Sanyal AJ, Harrison SA, Ratziu V, Abdelmalek MF, Diehl AM, Caldwell S, Shiffman ML, Aguilar Schall R, Jia C, McColgan B, Djedjos CS, McHutchison JG, Subramanian GM, Myers RP, Younossi Z, Muir AJ, Afdhal NH, Bosch J, Goodman Z.

Hepatology. 2019 Apr 16. doi: 10.1002/hep.30664. [Epub ahead of print]

PMID:
30993748
2.

Disease pathways and molecular mechanisms of nonalcoholic steatohepatitis.

Wegermann K, Diehl AM, Moylan CA.

Clin Liver Dis (Hoboken). 2018 Apr 20;11(4):87-91. doi: 10.1002/cld.709. eCollection 2018 Apr. Review. No abstract available.

3.

The companion of cellulose synthase 1 confers salt tolerance through a Tau-like mechanism in plants.

Kesten C, Wallmann A, Schneider R, McFarlane HE, Diehl A, Khan GA, van Rossum BJ, Lampugnani ER, Szymanski WG, Cremer N, Schmieder P, Ford KL, Seiter F, Heazlewood JL, Sanchez-Rodriguez C, Oschkinat H, Persson S.

Nat Commun. 2019 Feb 20;10(1):857. doi: 10.1038/s41467-019-08780-3.

4.

MicroRNA-375 Suppresses the Growth and Invasion of Fibrolamellar Carcinoma.

Dinh TA, Jewell ML, Kanke M, Francisco A, Sritharan R, Turnham RE, Lee S, Kastenhuber ER, Wauthier E, Guy CD, Yeung RS, Lowe SW, Reid LM, Scott JD, Diehl AM, Sethupathy P.

Cell Mol Gastroenterol Hepatol. 2019;7(4):803-817. doi: 10.1016/j.jcmgh.2019.01.008. Epub 2019 Feb 11.

5.

Dysregulated activation of fetal liver programme in acute liver failure.

Hyun J, Oh SH, Premont RT, Guy CD, Berg CL, Diehl AM.

Gut. 2019 Jun;68(6):1076-1087. doi: 10.1136/gutjnl-2018-317603. Epub 2019 Jan 22.

6.

Depressive symptoms and factors associated with depression and suicidal behavior in substances user in treatment: Focus on suicidal behavior and psychological problems.

Pillon SC, Vedana KGG, Teixeira JA, Dos Santos LA, de Souza RM, Diehl A, Rassool GH, Miasso AI.

Arch Psychiatr Nurs. 2019 Feb;33(1):70-76. doi: 10.1016/j.apnu.2018.11.005. Epub 2018 Nov 20.

PMID:
30663628
7.

Early childhood maltreatment experience and later sexual behavior in Brazilian adults undergoing treatment for substance dependence.

Diehl A, Clemente J, Pillon SC, Santana PRH, da Silva CJ, Mari JJ.

Braz J Psychiatry. 2019 May-Jun;41(3):199-207. doi: 10.1590/1516-4446-2017-0020. Epub 2018 Dec 6.

8.

Hepatocyte Notch activation induces liver fibrosis in nonalcoholic steatohepatitis.

Zhu C, Kim K, Wang X, Bartolome A, Salomao M, Dongiovanni P, Meroni M, Graham MJ, Yates KP, Diehl AM, Schwabe RF, Tabas I, Valenti L, Lavine JE, Pajvani UB.

Sci Transl Med. 2018 Nov 21;10(468). pii: eaat0344. doi: 10.1126/scitranslmed.aat0344.

PMID:
30463916
9.

Validation of Serum Test for Advanced Liver Fibrosis in Patients With Nonalcoholic Steatohepatitis.

Loomba R, Jain A, Diehl AM, Guy CD, Portenier D, Sudan R, Singh S, Faulkner C, Richards L, Hester KD, Okada L, Li XJ, Mimms L, Abdelmalek MF.

Clin Gastroenterol Hepatol. 2018 Nov 15. pii: S1542-3565(18)31247-3. doi: 10.1016/j.cgh.2018.11.004. [Epub ahead of print]

PMID:
30448594
10.

Microbial nitrogen limitation in the mammalian large intestine.

Reese AT, Pereira FC, Schintlmeister A, Berry D, Wagner M, Hale LP, Wu A, Jiang S, Durand HK, Zhou X, Premont RT, Diehl AM, O'Connell TM, Alberts SC, Kartzinel TR, Pringle RM, Dunn RR, Wright JP, David LA.

Nat Microbiol. 2018 Dec;3(12):1441-1450. doi: 10.1038/s41564-018-0267-7. Epub 2018 Oct 29.

11.

Developmental Morphogens & Recovery from Alcoholic Liver Disease.

Diehl AM.

Adv Exp Med Biol. 2018;1032:145-151. doi: 10.1007/978-3-319-98788-0_11. Review.

PMID:
30362097
12.

Branched chain amino acid transaminase 1 (BCAT1) is overexpressed and hypomethylated in patients with non-alcoholic fatty liver disease who experience adverse clinical events: A pilot study.

Wegermann K, Henao R, Diehl AM, Murphy SK, Abdelmalek MF, Moylan CA.

PLoS One. 2018 Sep 28;13(9):e0204308. doi: 10.1371/journal.pone.0204308. eCollection 2018. Erratum in: PLoS One. 2019 Feb 5;14(2):e0212144.

13.

Effect of varying prepartum dietary cation-anion difference and calcium concentration on postpartum mineral and metabolite status and milk production of multiparous cows.

Diehl AL, Bernard JK, Tao S, Smith TN, Kirk DJ, McLean DJ, Chapman JD.

J Dairy Sci. 2018 Nov;101(11):9915-9925. doi: 10.3168/jds.2018-14828. Epub 2018 Sep 13.

PMID:
30219430
14.

Sparstolonin B (SsnB) attenuates liver fibrosis via a parallel conjugate pathway involving P53-P21 axis, TGF-beta signaling and focal adhesion that is TLR4 dependent.

Dattaroy D, Seth RK, Sarkar S, Kimono D, Albadrani M, Chandrashekaran V, Hasson FA, Singh UP, Fan D, Nagarkatti M, Nagarkatti P, Diehl AM, Chatterjee S.

Eur J Pharmacol. 2018 Dec 15;841:33-48. doi: 10.1016/j.ejphar.2018.08.040. Epub 2018 Sep 5.

PMID:
30194936
15.

The conundrum of cryptogenic cirrhosis: Adverse outcomes without treatment options.

Younossi Z, Stepanova M, Sanyal AJ, Harrison SA, Ratziu V, Abdelmalek MF, Diehl AM, Caldwell S, Shiffman ML, Schall RA, McColgan B, Subramanian GM, Myers RP, Muir A, Afdhal NH, Bosch J, Goodman Z.

J Hepatol. 2018 Dec;69(6):1365-1370. doi: 10.1016/j.jhep.2018.08.013. Epub 2018 Aug 23.

PMID:
30144554
16.

Iron-Sulfur Cluster Biosynthesis in Algae with Complex Plastids.

Grosche C, Diehl A, Rensing SA, Maier UG.

Genome Biol Evol. 2018 Aug 1;10(8):2061-2071. doi: 10.1093/gbe/evy156.

17.

Short communication: Blood mineral and gas concentrations of calves born to cows fed prepartum diets differing in dietary cation-anion difference and calcium concentration.

Diehl AL, Bernard JK, Tao S, Smith TN, Marins T, Kirk DJ, McLean DJ, Chapman JD.

J Dairy Sci. 2018 Oct;101(10):9048-9051. doi: 10.3168/jds.2018-14829. Epub 2018 Aug 1.

PMID:
30077447
18.

RNA Binding Proteins Control Transdifferentiation of Hepatic Stellate Cells into Myofibroblasts.

Wang S, Jung Y, Hyun J, Friedersdorf M, Oh SH, Kim J, Premont RT, Keene JD, Diehl AM.

Cell Physiol Biochem. 2018;48(3):1215-1229. doi: 10.1159/000491987. Epub 2018 Jul 25.

19.

Markers of Tissue Repair and Cellular Aging Are Increased in the Liver Tissue of Patients With HIV Infection Regardless of Presence of HCV Coinfection.

Naggie S, Swiderska-Syn M, Choi S, Lusk S, Lan A, Ferrari G, Syn WK, Guy CD, Diehl AM.

Open Forum Infect Dis. 2018 Jun 11;5(7):ofy138. doi: 10.1093/ofid/ofy138. eCollection 2018 Jul.

20.

Simtuzumab Is Ineffective for Patients With Bridging Fibrosis or Compensated Cirrhosis Caused by Nonalcoholic Steatohepatitis.

Harrison SA, Abdelmalek MF, Caldwell S, Shiffman ML, Diehl AM, Ghalib R, Lawitz EJ, Rockey DC, Schall RA, Jia C, McColgan BJ, McHutchison JG, Subramanian GM, Myers RP, Younossi Z, Ratziu V, Muir AJ, Afdhal NH, Goodman Z, Bosch J, Sanyal AJ; GS-US-321-0105 and GS-US-321-0106 Investigators.

Gastroenterology. 2018 Oct;155(4):1140-1153. doi: 10.1053/j.gastro.2018.07.006. Epub 2018 Jul 7.

PMID:
29990488
21.

Towards a definite mouse model of NAFLD.

Castro RE, Diehl AM.

J Hepatol. 2018 Aug;69(2):272-274. doi: 10.1016/j.jhep.2018.05.002. Epub 2018 May 29. No abstract available.

PMID:
29858042
22.

The protofilament architecture of a de novo designed coiled coil-based amyloidogenic peptide.

de Freitas MS, Rezaei Araghi R, Brandenburg E, Leiterer J, Emmerling F, Folmert K, Gerling-Driessen UIM, Bardiaux B, Böttcher C, Pagel K, Diehl A, Berlepsch HV, Oschkinat H, Koksch B.

J Struct Biol. 2018 Sep;203(3):263-272. doi: 10.1016/j.jsb.2018.05.009. Epub 2018 May 29.

23.

Liver regeneration requires Yap1-TGFβ-dependent epithelial-mesenchymal transition in hepatocytes.

Oh SH, Swiderska-Syn M, Jewell ML, Premont RT, Diehl AM.

J Hepatol. 2018 Aug;69(2):359-367. doi: 10.1016/j.jhep.2018.05.008. Epub 2018 May 23.

24.

Prometheus revisited.

Chen KY, Shen X, Diehl AM.

J Clin Invest. 2018 Jun 1;128(6):2192-2193. doi: 10.1172/JCI120933. Epub 2018 Apr 30.

25.

High circulatory leptin mediated NOX-2-peroxynitrite-miR21 axis activate mesangial cells and promotes renal inflammatory pathology in nonalcoholic fatty liver disease.

Alhasson F, Seth RK, Sarkar S, Kimono DA, Albadrani MS, Dattaroy D, Chandrashekaran V, Scott GI, Raychoudhury S, Nagarkatti M, Nagarkatti P, Diehl AM, Chatterjee S.

Redox Biol. 2018 Jul;17:1-15. doi: 10.1016/j.redox.2018.04.002. Epub 2018 Apr 7.

26.

Cell type discovery using single-cell transcriptomics: implications for ontological representation.

Aevermann BD, Novotny M, Bakken T, Miller JA, Diehl AD, Osumi-Sutherland D, Lasken RS, Lein ES, Scheuermann RH.

Hum Mol Genet. 2018 May 1;27(R1):R40-R47. doi: 10.1093/hmg/ddy100.

27.

The hedgehog pathway in nonalcoholic fatty liver disease.

Verdelho Machado M, Diehl AM.

Crit Rev Biochem Mol Biol. 2018 Jun;53(3):264-278. doi: 10.1080/10409238.2018.1448752. Epub 2018 Mar 20. Review.

28.

Structural changes of TasA in biofilm formation of Bacillus subtilis.

Diehl A, Roske Y, Ball L, Chowdhury A, Hiller M, Molière N, Kramer R, Stöppler D, Worth CL, Schlegel B, Leidert M, Cremer N, Erdmann N, Lopez D, Stephanowitz H, Krause E, van Rossum BJ, Schmieder P, Heinemann U, Turgay K, Akbey Ü, Oschkinat H.

Proc Natl Acad Sci U S A. 2018 Mar 27;115(13):3237-3242. doi: 10.1073/pnas.1718102115. Epub 2018 Mar 12.

29.

Nonalcoholic Steatohepatitis.

Diehl AM, Day C.

N Engl J Med. 2018 Feb 22;378(8):781. doi: 10.1056/NEJMc1716786. No abstract available.

PMID:
29466150
30.

Fructose and sugar: A major mediator of non-alcoholic fatty liver disease.

Jensen T, Abdelmalek MF, Sullivan S, Nadeau KJ, Green M, Roncal C, Nakagawa T, Kuwabara M, Sato Y, Kang DH, Tolan DR, Sanchez-Lozada LG, Rosen HR, Lanaspa MA, Diehl AM, Johnson RJ.

J Hepatol. 2018 May;68(5):1063-1075. doi: 10.1016/j.jhep.2018.01.019. Epub 2018 Feb 2. Review.

31.

Relationships between lymphocyte counts and treatment-related toxicities and clinical responses in patients with solid tumors treated with PD-1 checkpoint inhibitors.

Diehl A, Yarchoan M, Hopkins A, Jaffee E, Grossman SA.

Oncotarget. 2017 Dec 14;8(69):114268-114280. doi: 10.18632/oncotarget.23217. eCollection 2017 Dec 26.

32.

DNA methylation signatures reflect aging in patients with nonalcoholic steatohepatitis.

Loomba R, Gindin Y, Jiang Z, Lawitz E, Caldwell S, Djedjos CS, Xu R, Chung C, Myers RP, Subramanian GM, Goodman Z, Charlton M, Afdhal NH, Diehl AM.

JCI Insight. 2018 Jan 25;3(2). pii: 96685. doi: 10.1172/jci.insight.96685. eCollection 2018 Jan 25.

33.

Erectile Dysfunction Symptoms in Polydrug Abusers Seeking Treatment.

Clemente J, Diehl A, Santana PROH, da Silva CJ, Pillon SC, Mari JJ.

Subst Use Misuse. 2018 Mar 21;53(4):704. doi: 10.1080/10826084.2017.1413116. Epub 2018 Jan 24. No abstract available.

PMID:
29364759
34.

Conserved and species-specific transcription factor co-binding patterns drive divergent gene regulation in human and mouse.

Diehl AG, Boyle AP.

Nucleic Acids Res. 2018 Feb 28;46(4):1878-1894. doi: 10.1093/nar/gky018.

35.

Cells in experimental life sciences - challenges and solution to the rapid evolution of knowledge.

Sarntivijai S, Diehl AD, He Y.

BMC Bioinformatics. 2017 Dec 21;18(Suppl 17):560. doi: 10.1186/s12859-017-1976-2.

36.

Hedgehog-YAP Signaling Pathway Regulates Glutaminolysis to Control Activation of Hepatic Stellate Cells.

Du K, Hyun J, Premont RT, Choi SS, Michelotti GA, Swiderska-Syn M, Dalton GD, Thelen E, Rizi BS, Jung Y, Diehl AM.

Gastroenterology. 2018 Apr;154(5):1465-1479.e13. doi: 10.1053/j.gastro.2017.12.022. Epub 2018 Jan 3.

37.

Abortion and sex-related conditions in substance-dependent Brazilian patients.

Diehl A, Pillon SC, Santos MAD, Laranjeira R.

Cad Saude Publica. 2017 Nov 21;33(11):e00143416. doi: 10.1590/0102-311X00143416.

38.

Cause, Pathogenesis, and Treatment of Nonalcoholic Steatohepatitis.

Diehl AM, Day C.

N Engl J Med. 2017 Nov 23;377(21):2063-2072. doi: 10.1056/NEJMra1503519. Review. No abstract available.

PMID:
29166236
39.

Association Between Cytokines and Liver Histology in Children with Nonalcoholic Fatty Liver Disease.

Perito ER, Ajmera V, Bass NM, Rosenthal P, Lavine JE, Schwimmer JB, Yates KP, Diehl AM, Molleston JP, Murray KF, Scheimann A, Gill R, Glidden D, Aouizerat B.

Hepatol Commun. 2017 Sep;1(7):609-622. doi: 10.1002/hep4.1068. Epub 2017 Jul 17.

40.

Pump head thrombosis in extracorporeal membrane oxygenation (ECMO).

Diehl A, Gantner D.

Intensive Care Med. 2018 Mar;44(3):376-377. doi: 10.1007/s00134-017-4976-9. Epub 2017 Nov 6. No abstract available.

PMID:
29110033
41.

Hedgehog signalling in liver pathophysiology.

Machado MV, Diehl AM.

J Hepatol. 2018 Mar;68(3):550-562. doi: 10.1016/j.jhep.2017.10.017. Epub 2017 Oct 26. Review.

42.

Metabolic Syndrome and Associated Diseases: From the Bench to the Clinic.

Mendrick DL, Diehl AM, Topor LS, Dietert RR, Will Y, La Merrill MA, Bouret S, Varma V, Hastings KL, Schug TT, Emeigh Hart SG, Burleson FG.

Toxicol Sci. 2018 Mar 1;162(1):36-42. doi: 10.1093/toxsci/kfx233. Review.

43.

The ASK1 inhibitor selonsertib in patients with nonalcoholic steatohepatitis: A randomized, phase 2 trial.

Loomba R, Lawitz E, Mantry PS, Jayakumar S, Caldwell SH, Arnold H, Diehl AM, Djedjos CS, Han L, Myers RP, Subramanian GM, McHutchison JG, Goodman ZD, Afdhal NH, Charlton MR; GS-US-384-1497 Investigators.

Hepatology. 2017 Sep 11. doi: 10.1002/hep.29514. [Epub ahead of print] Erratum in: Hepatology. 2018 May;67(5):2063.

44.

Paraphilic Thoughts, Behaviors and Sex Addiction in a Sample of Persons Who Use Drugs: A Cross-Sectional Study.

Clemente J, Pillon SC, Mari JJ, da Silva CJ, Santana PRH, Diehl A.

J Addict Med. 2017 Sep/Oct;11(5):377-385. doi: 10.1097/ADM.0000000000000337.

PMID:
28727662
45.

Sexual addiction in drug addicts: The impact of drug of choice and poly-addiction.

Antonio N, Diehl A, Niel M, Pillon S, Ratto L, Pinheiro MC, Silveira D, Otani TZ, Otani V, Cordeiro Q, Ushida R.

Rev Assoc Med Bras (1992). 2017 May;63(5):414-421. doi: 10.1590/1806-9282.63.05.414.

46.

Thymosin beta-4 regulates activation of hepatic stellate cells via hedgehog signaling.

Kim J, Hyun J, Wang S, Lee C, Lee JW, Moon EY, Cha H, Diehl AM, Jung Y.

Sci Rep. 2017 Jun 19;7(1):3815. doi: 10.1038/s41598-017-03782-x.

47.

Social stigma, legal and public health barriers faced by the third gender phenomena in Brazil, India and Mexico: Travestis, hijras and muxes.

Diehl A, Vieira DL, Zaneti MM, Fanganiello A, Sharan P, Robles R, de Jesus Mari J.

Int J Soc Psychiatry. 2017 Aug;63(5):389-399. doi: 10.1177/0020764017706989. Epub 2017 May 29. Review.

PMID:
28552025
48.

HMGB1-RAGE pathway drives peroxynitrite signaling-induced IBD-like inflammation in murine nonalcoholic fatty liver disease.

Chandrashekaran V, Seth RK, Dattaroy D, Alhasson F, Ziolenka J, Carson J, Berger FG, Kalyanaraman B, Diehl AM, Chatterjee S.

Redox Biol. 2017 Oct;13:8-19. doi: 10.1016/j.redox.2017.05.005. Epub 2017 May 10.

49.

Reply.

Yang JD, Abdelmalek MF, Guy CD, Diehl AM, Suzuki A.

Clin Gastroenterol Hepatol. 2018 Oct;16(10):1684. doi: 10.1016/j.cgh.2017.05.003. Epub 2017 May 11. No abstract available.

PMID:
28502788
50.

Erectile Dysfunction Symptoms in Polydrug Dependents Seeking Treatment.

Clemente J, Diehl A, Santana PROH, da Silva CJ, Pillon SC, Mari JJ.

Subst Use Misuse. 2017 Oct 15;52(12):1565-1574. doi: 10.1080/10826084.2017.1290114. Epub 2017 May 4. Erratum in: Subst Use Misuse. 2018 Mar 21;53(4):704.

PMID:
28471320

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