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Items: 1 to 50 of 133

1.

The Role of Extracellular Matrix Expression, ERK1/2 Signaling and Cell Cohesiveness for Cartilage Yield from iPSCs.

Buchert J, Diederichs S, Kreuser U, Merle C, Richter W.

Int J Mol Sci. 2019 Sep 2;20(17). pii: E4295. doi: 10.3390/ijms20174295.

2.

The Clinically Used Iron Chelator Deferasirox Is an Inhibitor of Epigenetic JumonjiC Domain-Containing Histone Demethylases.

Roatsch M, Hoffmann I, Abboud MI, Hancock RL, Tarhonskaya H, Hsu KF, Wilkins SE, Yeh TL, Lippl K, Serrer K, Moneke I, Ahrens TD, Robaa D, Wenzler S, Barthes NPF, Franz H, Sippl W, Lassmann S, Diederichs S, Schleicher E, Schofield CJ, Kawamura A, Schüle R, Jung M.

ACS Chem Biol. 2019 Aug 16;14(8):1737-1750. doi: 10.1021/acschembio.9b00289. Epub 2019 Jul 19.

PMID:
31287655
3.

FLASHForward: plasma wakefield accelerator science for high-average-power applications.

D'Arcy R, Aschikhin A, Bohlen S, Boyle G, Brümmer T, Chappell J, Diederichs S, Foster B, Garland MJ, Goldberg L, Gonzalez P, Karstensen S, Knetsch A, Kuang P, Libov V, Ludwig K, Martinez de la Ossa A, Marutzky F, Meisel M, Mehrling TJ, Niknejadi P, Põder K, Pourmoussavi P, Quast M, Röckemann JH, Schaper L, Schmidt B, Schröder S, Schwinkendorf JP, Sheeran B, Tauscher G, Wesch S, Wing M, Winkler P, Zeng M, Osterhoff J.

Philos Trans A Math Phys Eng Sci. 2019 Aug 12;377(2151):20180392. doi: 10.1098/rsta.2018.0392. Epub 2019 Jun 24.

PMID:
31230573
4.

A pan-cancer analysis of synonymous mutations.

Sharma Y, Miladi M, Dukare S, Boulay K, Caudron-Herger M, Groß M, Backofen R, Diederichs S.

Nat Commun. 2019 Jun 12;10(1):2569. doi: 10.1038/s41467-019-10489-2.

5.

R-DeeP: Proteome-wide and Quantitative Identification of RNA-Dependent Proteins by Density Gradient Ultracentrifugation.

Caudron-Herger M, Rusin SF, Adamo ME, Seiler J, Schmid VK, Barreau E, Kettenbach AN, Diederichs S.

Mol Cell. 2019 Jul 11;75(1):184-199.e10. doi: 10.1016/j.molcel.2019.04.018. Epub 2019 May 7.

PMID:
31076284
6.

Regulation of WNT5A and WNT11 during MSC in vitro chondrogenesis: WNT inhibition lowers BMP and hedgehog activity, and reduces hypertrophy.

Diederichs S, Tonnier V, März M, Dreher SI, Geisbüsch A, Richter W.

Cell Mol Life Sci. 2019 Oct;76(19):3875-3889. doi: 10.1007/s00018-019-03099-0. Epub 2019 Apr 12.

PMID:
30980110
7.

A high-throughput screen identifies the long non-coding RNA DRAIC as a regulator of autophagy.

Tiessen I, Abildgaard MH, Lubas M, Gylling HM, Steinhauer C, Pietras EJ, Diederichs S, Frankel LB, Lund AH.

Oncogene. 2019 Jun;38(26):5127-5141. doi: 10.1038/s41388-019-0783-9. Epub 2019 Mar 14.

PMID:
30872794
8.

LINC00261 and the Adjacent Gene FOXA2 Are Epithelial Markers and Are Suppressed during Lung Cancer Tumorigenesis and Progression.

Dhamija S, Becker AC, Sharma Y, Myacheva K, Seiler J, Diederichs S.

Noncoding RNA. 2018 Dec 28;5(1). pii: E2. doi: 10.3390/ncrna5010002.

9.

Correction: Generation of murine tumor cell lines deficient in MHC molecule surface expression using the CRISPR/Cas9 system.

Das K, Eisel D, Lenkl C, Goyal A, Diederichs S, Dickes E, Osen W, Eichmüller SB.

PLoS One. 2018 Dec 19;13(12):e0209719. doi: 10.1371/journal.pone.0209719. eCollection 2018.

10.

Targeting LINC00673 expression triggers cellular senescence in lung cancer.

Roth A, Boulay K, Groß M, Polycarpou-Schwarz M, Mallette FA, Regnier M, Bida O, Ginsberg D, Warth A, Schnabel PA, Muley T, Meister M, Zabeck H, Hoffmann H, Diederichs S.

RNA Biol. 2018;15(12):1499-1511. doi: 10.1080/15476286.2018.1553481. Epub 2018 Dec 7.

PMID:
30499379
11.

RNA motifs and combinatorial prediction of interactions, stability and localization of noncoding RNAs.

Gandhi M, Caudron-Herger M, Diederichs S.

Nat Struct Mol Biol. 2018 Dec;25(12):1070-1076. doi: 10.1038/s41594-018-0155-0. Epub 2018 Nov 12. Review.

PMID:
30420773
12.

StarPEG/heparin-hydrogel based in vivo engineering of stable bizonal cartilage with a calcified bottom layer.

Kunisch E, Knauf AK, Hesse E, Freudenberg U, Werner C, Bothe F, Diederichs S, Richter W.

Biofabrication. 2018 Oct 30;11(1):015001. doi: 10.1088/1758-5090/aae75a.

PMID:
30376451
13.

MIR100 host gene-encoded lncRNAs regulate cell cycle by modulating the interaction between HuR and its target mRNAs.

Sun Q, Tripathi V, Yoon JH, Singh DK, Hao Q, Min KW, Davila S, Zealy RW, Li XL, Polycarpou-Schwarz M, Lehrmann E, Zhang Y, Becker KG, Freier SM, Zhu Y, Diederichs S, Prasanth SG, Lal A, Gorospe M, Prasanth KV.

Nucleic Acids Res. 2018 Nov 2;46(19):10405-10416. doi: 10.1093/nar/gky696.

14.

Stimulation of calvarial bone healing with human bone marrow stromal cells versus inhibition with adipose-tissue stromal cells on nanostructured β-TCP-collagen.

Bothe F, Lotz B, Seebach E, Fischer J, Hesse E, Diederichs S, Richter W.

Acta Biomater. 2018 Aug;76:135-145. doi: 10.1016/j.actbio.2018.06.026. Epub 2018 Jun 20.

PMID:
29933108
15.

A novel long non-coding RNA from NBL2 pericentromeric macrosatellite forms a perinucleolar aggregate structure in colon cancer.

Dumbovic G, Biayna J, Banús J, Samuelsson J, Roth A, Diederichs S, Alonso S, Buschbeck M, Perucho M, Forcales SV.

Nucleic Acids Res. 2018 Jun 20;46(11):5504-5524. doi: 10.1093/nar/gky263.

16.

The Long Noncoding RNA Cancer Susceptibility 9 and RNA Binding Protein Heterogeneous Nuclear Ribonucleoprotein L Form a Complex and Coregulate Genes Linked to AKT Signaling.

Klingenberg M, Groß M, Goyal A, Polycarpou-Schwarz M, Miersch T, Ernst AS, Leupold J, Patil N, Warnken U, Allgayer H, Longerich T, Schirmacher P, Boutros M, Diederichs S.

Hepatology. 2018 Nov;68(5):1817-1832. doi: 10.1002/hep.30102. Epub 2018 Oct 12.

PMID:
29790588
17.

The cancer-associated microprotein CASIMO1 controls cell proliferation and interacts with squalene epoxidase modulating lipid droplet formation.

Polycarpou-Schwarz M, Groß M, Mestdagh P, Schott J, Grund SE, Hildenbrand C, Rom J, Aulmann S, Sinn HP, Vandesompele J, Diederichs S.

Oncogene. 2018 Aug;37(34):4750-4768. doi: 10.1038/s41388-018-0281-5. Epub 2018 May 16.

PMID:
29765154
18.

Designer epigenome modifiers enable robust and sustained gene silencing in clinically relevant human cells.

Mlambo T, Nitsch S, Hildenbeutel M, Romito M, Müller M, Bossen C, Diederichs S, Cornu TI, Cathomen T, Mussolino C.

Nucleic Acids Res. 2018 May 18;46(9):4456-4468. doi: 10.1093/nar/gky171.

19.

Online measurement of the respiratory activity in shake flasks enables the identification of cultivation phases and patterns indicating recombinant protein production in various Escherichia coli host strains.

Ihling N, Bittner N, Diederichs S, Schelden M, Korona A, Höfler GT, Fulton A, Jaeger KE, Honda K, Ohtake H, Büchs J.

Biotechnol Prog. 2018 Mar;34(2):315-327. doi: 10.1002/btpr.2600. Epub 2018 Jan 17.

PMID:
29314728
20.

Pulmonary metastasectomy for thyroid cancer as salvage therapy for radioactive iodine-refractory metastases.

Moneke I, Kaifi JT, Kloeser R, Samson P, Haager B, Wiesemann S, Diederichs S, Passlick B.

Eur J Cardiothorac Surg. 2018 Mar 1;53(3):625-630. doi: 10.1093/ejcts/ezx367.

PMID:
29092022
21.

Stimulation of a calcified cartilage connecting zone by GDF-5-augmented fibrin hydrogel in a novel layered ectopic in vivo model.

Diederichs S, Renz Y, Hagmann S, Lotz B, Seebach E, Richter W.

J Biomed Mater Res B Appl Biomater. 2018 Aug;106(6):2214-2224. doi: 10.1002/jbm.b.34027. Epub 2017 Oct 25.

PMID:
29068568
22.

Evaluation of fluorescence in situ hybridization techniques to study long non-coding RNA expression in cultured cells.

Soares RJ, Maglieri G, Gutschner T, Diederichs S, Lund AH, Nielsen BS, Holmstrøm K.

Nucleic Acids Res. 2018 Jan 9;46(1):e4. doi: 10.1093/nar/gkx946.

23.

A cautionary tale of sense-antisense gene pairs: independent regulation despite inverse correlation of expression.

Goyal A, Fiškin E, Gutschner T, Polycarpou-Schwarz M, Groß M, Neugebauer J, Gandhi M, Caudron-Herger M, Benes V, Diederichs S.

Nucleic Acids Res. 2017 Dec 1;45(21):12496-12508. doi: 10.1093/nar/gkx952.

24.

Mitochondrial mutations in human cancer: Curation of translation.

Caudron-Herger M, Diederichs S.

RNA Biol. 2018 Jan 2;15(1):62-69. doi: 10.1080/15476286.2017.1373239. Epub 2017 Sep 26.

25.

Tumor-derived exosomes modulate PD-L1 expression in monocytes.

Haderk F, Schulz R, Iskar M, Cid LL, Worst T, Willmund KV, Schulz A, Warnken U, Seiler J, Benner A, Nessling M, Zenz T, Göbel M, Dürig J, Diederichs S, Paggetti J, Moussay E, Stilgenbauer S, Zapatka M, Lichter P, Seiffert M.

Sci Immunol. 2017 Jul 28;2(13). pii: eaah5509. doi: 10.1126/sciimmunol.aah5509.

PMID:
28754746
26.

The long non-coding RNA LINC00152 is essential for cell cycle progression through mitosis in HeLa cells.

Nötzold L, Frank L, Gandhi M, Polycarpou-Schwarz M, Groß M, Gunkel M, Beil N, Erfle H, Harder N, Rohr K, Trendel J, Krijgsveld J, Longerich T, Schirmacher P, Boutros M, Erhardt S, Diederichs S.

Sci Rep. 2017 May 23;7(1):2265. doi: 10.1038/s41598-017-02357-0.

27.

Non-coding RNA in hepatocellular carcinoma: Mechanisms, biomarkers and therapeutic targets.

Klingenberg M, Matsuda A, Diederichs S, Patel T.

J Hepatol. 2017 Sep;67(3):603-618. doi: 10.1016/j.jhep.2017.04.009. Epub 2017 Apr 22. Review.

PMID:
28438689
28.

Generation of murine tumor cell lines deficient in MHC molecule surface expression using the CRISPR/Cas9 system.

Das K, Eisel D, Lenkl C, Goyal A, Diederichs S, Dickes E, Osen W, Eichmüller SB.

PLoS One. 2017 Mar 16;12(3):e0174077. doi: 10.1371/journal.pone.0174077. eCollection 2017. Erratum in: PLoS One. 2018 Dec 19;13(12):e0209719.

29.

Challenges of CRISPR/Cas9 applications for long non-coding RNA genes.

Goyal A, Myacheva K, Groß M, Klingenberg M, Duran Arqué B, Diederichs S.

Nucleic Acids Res. 2017 Feb 17;45(3):e12. doi: 10.1093/nar/gkw883.

30.

The lncRNA VELUCT strongly regulates viability of lung cancer cells despite its extremely low abundance.

Seiler J, Breinig M, Caudron-Herger M, Polycarpou-Schwarz M, Boutros M, Diederichs S.

Nucleic Acids Res. 2017 May 19;45(9):5458-5469. doi: 10.1093/nar/gkx076.

31.

Applying an ecological framework to understand transition pathways to post-secondary education for youth with physical disabilities.

Lindsay S, Duncanson M, Niles-Campbell N, McDougall C, Diederichs S, Menna-Dack D.

Disabil Rehabil. 2018 Feb;40(3):277-286. doi: 10.1080/09638288.2016.1250171. Epub 2016 Nov 20.

PMID:
27868448
32.

Epigenetic inactivation of the p53-induced long noncoding RNA TP53 target 1 in human cancer.

Diaz-Lagares A, Crujeiras AB, Lopez-Serra P, Soler M, Setien F, Goyal A, Sandoval J, Hashimoto Y, Martinez-Cardús A, Gomez A, Heyn H, Moutinho C, Espada J, Vidal A, Paúles M, Galán M, Sala N, Akiyama Y, Martínez-Iniesta M, Farré L, Villanueva A, Gross M, Diederichs S, Guil S, Esteller M.

Proc Natl Acad Sci U S A. 2016 Nov 22;113(47):E7535-E7544. Epub 2016 Nov 7.

33.

LIMT is a novel metastasis inhibiting lncRNA suppressed by EGF and downregulated in aggressive breast cancer.

Sas-Chen A, Aure MR, Leibovich L, Carvalho S, Enuka Y, Körner C, Polycarpou-Schwarz M, Lavi S, Nevo N, Kuznetsov Y, Yuan J, Azuaje F; Oslo Breast Cancer Research Consortium (OSBREAC)SauerTorillGeislerJürgenHofvindSolveigBathenTone FBorgenElinEngebråtenOlavFodstadØysteinGarredØysteinGeitvikGry AarumKåresenRolfNaumeBjørnMælandsmoGunhild MariRussnesHege GSchlichtingEllenSørlieThereseLingjærdeOle ChristianSahlbergKristine KleiviSkjervenHelle KristineFritzmanBritt, Ulitsky I, Diederichs S, Wiemann S, Yakhini Z, Kristensen VN, Børresen-Dale AL, Yarden Y.

EMBO Mol Med. 2016 Sep 1;8(9):1052-64. doi: 10.15252/emmm.201606198. Print 2016 Sep.

34.

Alternative splicing affects the subcellular localization of Drosha.

Link S, Grund SE, Diederichs S.

Nucleic Acids Res. 2016 Jun 20;44(11):5330-43. doi: 10.1093/nar/gkw400. Epub 2016 May 16.

35.

The dark matter of the cancer genome: aberrations in regulatory elements, untranslated regions, splice sites, non-coding RNA and synonymous mutations.

Diederichs S, Bartsch L, Berkmann JC, Fröse K, Heitmann J, Hoppe C, Iggena D, Jazmati D, Karschnia P, Linsenmeier M, Maulhardt T, Möhrmann L, Morstein J, Paffenholz SV, Röpenack P, Rückert T, Sandig L, Schell M, Steinmann A, Voss G, Wasmuth J, Weinberger ME, Wullenkord R.

EMBO Mol Med. 2016 May 2;8(5):442-57. doi: 10.15252/emmm.201506055. Print 2016 May. Review.

36.

Differential Regulation of SOX9 Protein During Chondrogenesis of Induced Pluripotent Stem Cells Versus Mesenchymal Stromal Cells: A Shortcoming for Cartilage Formation.

Diederichs S, Gabler J, Autenrieth J, Kynast KL, Merle C, Walles H, Utikal J, Richter W.

Stem Cells Dev. 2016 Apr 15;25(8):598-609. doi: 10.1089/scd.2015.0312. Epub 2016 Mar 23.

PMID:
26906619
37.

From junk to master regulators of invasion: lncRNA functions in migration, EMT and metastasis.

Dhamija S, Diederichs S.

Int J Cancer. 2016 Jul 15;139(2):269-80. doi: 10.1002/ijc.30039. Epub 2016 Mar 2. Review.

38.

Mitotic Diversity in Homeostatic Human Interfollicular Epidermis.

Nöske K, Stark HJ, Nevaril L, Berning M, Langbein L, Goyal A, Diederichs S, Boukamp P.

Int J Mol Sci. 2016 Jan 28;17(2). pii: E167. doi: 10.3390/ijms17020167.

39.

The expression of a viral microRNA is regulated by clustering to allow optimal B cell transformation.

Haar J, Contrant M, Bernhardt K, Feederle R, Diederichs S, Pfeffer S, Delecluse HJ.

Nucleic Acids Res. 2016 Feb 18;44(3):1326-41. doi: 10.1093/nar/gkv1330. Epub 2015 Dec 3.

40.

Stage-Specific miRs in Chondrocyte Maturation: Differentiation-Dependent and Hypertrophy-Related miR Clusters and the miR-181 Family.

Gabler J, Ruetze M, Kynast KL, Grossner T, Diederichs S, Richter W.

Tissue Eng Part A. 2015 Dec;21(23-24):2840-51. doi: 10.1089/ten.TEA.2015.0352. Epub 2015 Nov 13.

PMID:
26431739
41.

Long Noncoding RNAs in Lung Cancer.

Roth A, Diederichs S.

Curr Top Microbiol Immunol. 2016;394:57-110. doi: 10.1007/82_2015_444. Review.

PMID:
26037047
42.

Molecular biology: Rap and chirp about X inactivation.

Roth A, Diederichs S.

Nature. 2015 May 14;521(7551):170-1. doi: 10.1038/521170a. No abstract available.

PMID:
25971508
43.

Quantifying ligand-cell interactions and determination of the surface concentrations of ligands on hydrogel films: The measurement challenge.

Beer MV, Hahn K, Diederichs S, Fabry M, Singh S, Spencer SJ, Salber J, Möller M, Shard AG, Groll J.

Biointerphases. 2015 Jun 8;10(2):021007. doi: 10.1116/1.4919015.

PMID:
25956179
44.

Micro-terminator: 'Hasta la vista, lncRNA!'.

Diederichs S.

Nat Struct Mol Biol. 2015 Apr;22(4):279-81. doi: 10.1038/nsmb.3001.

PMID:
25837873
45.

microRNA-379 couples glucocorticoid hormones to dysfunctional lipid homeostasis.

de Guia RM, Rose AJ, Sommerfeld A, Seibert O, Strzoda D, Zota A, Feuchter Y, Krones-Herzig A, Sijmonsma T, Kirilov M, Sticht C, Gretz N, Dallinga-Thie G, Diederichs S, Klöting N, Blüher M, Berriel Diaz M, Herzig S.

EMBO J. 2015 Feb 3;34(3):344-60. doi: 10.15252/embj.201490464. Epub 2014 Dec 15.

46.

Phenotyping the quality of complex medium components by simple online-monitored shake flask experiments.

Diederichs S, Korona A, Staaden A, Kroutil W, Honda K, Ohtake H, Büchs J.

Microb Cell Fact. 2014 Nov 7;13:149. doi: 10.1186/s12934-014-0149-5.

47.

tRNAs: new tricks from old dogs.

Stoecklin G, Diederichs S.

EMBO J. 2014 Sep 17;33(18):1981-3. doi: 10.15252/embj.201489634. Epub 2014 Sep 12.

48.

Xenogeneic transplantation of articular chondrocytes into full-thickness articular cartilage defects in minipigs: fate of cells and the role of macrophages.

Niemietz T, Zass G, Hagmann S, Diederichs S, Gotterbarm T, Richter W.

Cell Tissue Res. 2014 Dec;358(3):749-61. doi: 10.1007/s00441-014-1982-x. Epub 2014 Aug 17.

PMID:
25129109
49.

Minireactor-based high-throughput temperature profiling for the optimization of microbial and enzymatic processes.

Kunze M, Lattermann C, Diederichs S, Kroutil W, Büchs J.

J Biol Eng. 2014 Aug 4;8:22. doi: 10.1186/1754-1611-8-22. eCollection 2014.

50.

Cross-section perimeter is a suitable parameter to describe the effects of different baffle geometries in shaken microtiter plates.

Lattermann C, Funke M, Hansen S, Diederichs S, Büchs J.

J Biol Eng. 2014 Jul 15;8:18. doi: 10.1186/1754-1611-8-18. eCollection 2014.

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