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Items: 1 to 50 of 136

1.

Fast and accurate data collection for macromolecular crystallography using the JUNGFRAU detector.

Leonarski F, Redford S, Mozzanica A, Lopez-Cuenca C, Panepucci E, Nass K, Ozerov D, Vera L, Olieric V, Buntschu D, Schneider R, Tinti G, Froejdh E, Diederichs K, Bunk O, Schmitt B, Wang M.

Nat Methods. 2018 Oct;15(10):799-804. doi: 10.1038/s41592-018-0143-7. Epub 2018 Oct 1.

PMID:
30275593
2.

In situ serial crystallography for rapid de novo membrane protein structure determination.

Huang CY, Olieric V, Howe N, Warshamanage R, Weinert T, Panepucci E, Vogeley L, Basu S, Diederichs K, Caffrey M, Wang M.

Commun Biol. 2018 Aug 27;1:124. doi: 10.1038/s42003-018-0123-6. eCollection 2018.

3.

Snapshots of a modified nucleotide moving through the confines of a DNA polymerase.

Kropp HM, Dürr SL, Peter C, Diederichs K, Marx A.

Proc Natl Acad Sci U S A. 2018 Oct 2;115(40):9992-9997. doi: 10.1073/pnas.1811518115. Epub 2018 Sep 17.

4.

Crystal structures of ternary complexes of archaeal B-family DNA polymerases.

Kropp HM, Betz K, Wirth J, Diederichs K, Marx A.

PLoS One. 2017 Dec 6;12(12):e0188005. doi: 10.1371/journal.pone.0188005. eCollection 2017.

5.

Structural basis for the selective incorporation of an artificial nucleotide opposite a DNA adduct by a DNA polymerase.

Betz K, Nilforoushan A, Wyss LA, Diederichs K, Sturla SJ, Marx A.

Chem Commun (Camb). 2017 Nov 23;53(94):12704-12707. doi: 10.1039/c7cc07173f.

PMID:
29136072
6.

Structural Basis for Expansion of the Genetic Alphabet with an Artificial Nucleobase Pair.

Betz K, Kimoto M, Diederichs K, Hirao I, Marx A.

Angew Chem Int Ed Engl. 2017 Sep 18;56(39):12000-12003. doi: 10.1002/anie.201704190. Epub 2017 Jun 27.

PMID:
28594080
7.

Serial Synchrotron X-Ray Crystallography (SSX).

Diederichs K, Wang M.

Methods Mol Biol. 2017;1607:239-272. doi: 10.1007/978-1-4939-7000-1_10.

PMID:
28573576
8.

Dissecting random and systematic differences between noisy composite data sets.

Diederichs K.

Acta Crystallogr D Struct Biol. 2017 Apr 1;73(Pt 4):286-293. doi: 10.1107/S2059798317000699. Epub 2017 Mar 31.

9.

Crystal structure and mechanistic basis of a functional homolog of the antigen transporter TAP.

Nöll A, Thomas C, Herbring V, Zollmann T, Barth K, Mehdipour AR, Tomasiak TM, Brüchert S, Joseph B, Abele R, Oliéric V, Wang M, Diederichs K, Hummer G, Stroud RM, Pos KM, Tampé R.

Proc Natl Acad Sci U S A. 2017 Jan 24;114(4):E438-E447. doi: 10.1073/pnas.1620009114. Epub 2017 Jan 9.

10.

ContaMiner and ContaBase: a webserver and database for early identification of unwantedly crystallized protein contaminants.

Hungler A, Momin A, Diederichs K, Arold ST.

J Appl Crystallogr. 2016 Nov 2;49(Pt 6):2252-2258. eCollection 2016 Dec 1.

11.

Structural Basis for the KlenTaq DNA Polymerase Catalysed Incorporation of Alkene- versus Alkyne-Modified Nucleotides.

Hottin A, Betz K, Diederichs K, Marx A.

Chemistry. 2017 Feb 10;23(9):2109-2118. doi: 10.1002/chem.201604515. Epub 2017 Jan 18.

PMID:
27901305
12.

Bacterial flagellar capping proteins adopt diverse oligomeric states.

Postel S, Deredge D, Bonsor DA, Yu X, Diederichs K, Helmsing S, Vromen A, Friedler A, Hust M, Egelman EH, Beckett D, Wintrode PL, Sundberg EJ.

Elife. 2016 Sep 24;5. pii: e18857. doi: 10.7554/eLife.18857.

13.

A critical examination of the recently reported crystal structures of the human SMN protein.

Weiss MS, Diederichs K, Read RJ, Panjikar S, Van Duyne GD, Matera AG, Fischer U, Grimm C.

Hum Mol Genet. 2016 Aug 29;25(21):4717–4725. doi: 10.1093/hmg/ddw298.

14.

Identification of rogue datasets in serial crystallography.

Assmann G, Brehm W, Diederichs K.

J Appl Crystallogr. 2016 Apr 18;49(Pt 3):1021-1028. eCollection 2016 Jun 1.

15.

Recent developments in CrystFEL.

White TA, Mariani V, Brehm W, Yefanov O, Barty A, Beyerlein KR, Chervinskii F, Galli L, Gati C, Nakane T, Tolstikova A, Yamashita K, Yoon CH, Diederichs K, Chapman HN.

J Appl Crystallogr. 2016 Mar 29;49(Pt 2):680-689. eCollection 2016 Apr 1.

16.

Data publication with the structural biology data grid supports live analysis.

Meyer PA, Socias S, Key J, Ransey E, Tjon EC, Buschiazzo A, Lei M, Botka C, Withrow J, Neau D, Rajashankar K, Anderson KS, Baxter RH, Blacklow SC, Boggon TJ, Bonvin AM, Borek D, Brett TJ, Caflisch A, Chang CI, Chazin WJ, Corbett KD, Cosgrove MS, Crosson S, Dhe-Paganon S, Di Cera E, Drennan CL, Eck MJ, Eichman BF, Fan QR, Ferré-D'Amaré AR, Fromme JC, Garcia KC, Gaudet R, Gong P, Harrison SC, Heldwein EE, Jia Z, Keenan RJ, Kruse AC, Kvansakul M, McLellan JS, Modis Y, Nam Y, Otwinowski Z, Pai EF, Pereira PJ, Petosa C, Raman CS, Rapoport TA, Roll-Mecak A, Rosen MK, Rudenko G, Schlessinger J, Schwartz TU, Shamoo Y, Sondermann H, Tao YJ, Tolia NH, Tsodikov OV, Westover KD, Wu H, Foster I, Fraser JS, Maia FR, Gonen T, Kirchhausen T, Diederichs K, Crosas M, Sliz P.

Nat Commun. 2016 Mar 7;7:10882. doi: 10.1038/ncomms10882.

17.

In meso in situ serial X-ray crystallography of soluble and membrane proteins at cryogenic temperatures.

Huang CY, Olieric V, Ma P, Howe N, Vogeley L, Liu X, Warshamanage R, Weinert T, Panepucci E, Kobilka B, Diederichs K, Wang M, Caffrey M.

Acta Crystallogr D Struct Biol. 2016 Jan;72(Pt 1):93-112. doi: 10.1107/S2059798315021683. Epub 2016 Jan 1.

18.

Redox-coupled structural changes in nitrite reductase revealed by serial femtosecond and microfocus crystallography.

Fukuda Y, Tse KM, Suzuki M, Diederichs K, Hirata K, Nakane T, Sugahara M, Nango E, Tono K, Joti Y, Kameshima T, Song C, Hatsui T, Yabashi M, Nureki O, Matsumura H, Inoue T, Iwata S, Mizohata E.

J Biochem. 2016 May;159(5):527-38. doi: 10.1093/jb/mvv133. Epub 2016 Jan 14.

19.

Ternary structure reveals mechanism of a membrane diacylglycerol kinase.

Li D, Stansfeld PJ, Sansom MS, Keogh A, Vogeley L, Howe N, Lyons JA, Aragao D, Fromme P, Fromme R, Basu S, Grotjohann I, Kupitz C, Rendek K, Weierstall U, Zatsepin NA, Cherezov V, Liu W, Bandaru S, English NJ, Gati C, Barty A, Yefanov O, Chapman HN, Diederichs K, Messerschmidt M, Boutet S, Williams GJ, Marvin Seibert M, Caffrey M.

Nat Commun. 2015 Dec 17;6:10140. doi: 10.1038/ncomms10140.

20.

Crystallizing the 6S and 8S spliceosomal assembly intermediates: a complex project.

Pelz JP, Schindelin H, van Pee K, Kuper J, Kisker C, Diederichs K, Fischer U, Grimm C.

Acta Crystallogr D Biol Crystallogr. 2015 Oct;71(Pt 10):2040-53. doi: 10.1107/S1399004715014832. Epub 2015 Sep 26.

PMID:
26457428
21.

Response from Tanley et al. to Crystallography and chemistry should always go together: a cautionary tale of protein complexes with cisplatin and carboplatin.

Tanley SW, Diederichs K, Kroon-Batenburg LM, Levy C, Schreurs AM, Helliwell JR.

Acta Crystallogr D Biol Crystallogr. 2015 Sep;71(Pt 9):1982-3. doi: 10.1107/S1399004715014340. Epub 2015 Aug 28. No abstract available.

PMID:
26327388
22.

Structural Insights into Nonspecific Binding of DNA by TrmBL2, an Archaeal Chromatin Protein.

Ahmad MUD, Waege I, Hausner W, Thomm M, Boos W, Diederichs K, Welte W.

J Mol Biol. 2015 Oct 9;427(20):3216-3229. doi: 10.1016/j.jmb.2015.08.012. Epub 2015 Aug 20.

PMID:
26299937
23.

Chorismatase Mechanisms Reveal Fundamentally Different Types of Reaction in a Single Conserved Protein Fold.

Hubrich F, Juneja P, Müller M, Diederichs K, Welte W, Andexer JN.

J Am Chem Soc. 2015 Sep 2;137(34):11032-7. doi: 10.1021/jacs.5b05559. Epub 2015 Aug 19.

PMID:
26247872
24.

Crystallographic Data and Model Quality.

Diederichs K.

Methods Mol Biol. 2016;1320:147-73. doi: 10.1007/978-1-4939-2763-0_10.

PMID:
26227042
25.

Assessing and maximizing data quality in macromolecular crystallography.

Karplus PA, Diederichs K.

Curr Opin Struct Biol. 2015 Oct;34:60-8. doi: 10.1016/j.sbi.2015.07.003. Epub 2015 Jul 24. Review.

26.

Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser.

Kang Y, Zhou XE, Gao X, He Y, Liu W, Ishchenko A, Barty A, White TA, Yefanov O, Han GW, Xu Q, de Waal PW, Ke J, Tan MH, Zhang C, Moeller A, West GM, Pascal BD, Van Eps N, Caro LN, Vishnivetskiy SA, Lee RJ, Suino-Powell KM, Gu X, Pal K, Ma J, Zhi X, Boutet S, Williams GJ, Messerschmidt M, Gati C, Zatsepin NA, Wang D, James D, Basu S, Roy-Chowdhury S, Conrad CE, Coe J, Liu H, Lisova S, Kupitz C, Grotjohann I, Fromme R, Jiang Y, Tan M, Yang H, Li J, Wang M, Zheng Z, Li D, Howe N, Zhao Y, Standfuss J, Diederichs K, Dong Y, Potter CS, Carragher B, Caffrey M, Jiang H, Chapman HN, Spence JC, Fromme P, Weierstall U, Ernst OP, Katritch V, Gurevich VV, Griffin PR, Hubbell WL, Stevens RC, Cherezov V, Melcher K, Xu HE.

Nature. 2015 Jul 30;523(7562):561-7. doi: 10.1038/nature14656. Epub 2015 Jul 22.

27.

In meso in situ serial X-ray crystallography of soluble and membrane proteins.

Huang CY, Olieric V, Ma P, Panepucci E, Diederichs K, Wang M, Caffrey M.

Acta Crystallogr D Biol Crystallogr. 2015 Jun;71(Pt 6):1238-56. doi: 10.1107/S1399004715005210. Epub 2015 May 14.

28.

Integrin engagement by the helical RGD motif of the Helicobacter pylori CagL protein is regulated by pH-induced displacement of a neighboring helix.

Bonsor DA, Pham KT, Beadenkopf R, Diederichs K, Haas R, Beckett D, Fischer W, Sundberg EJ.

J Biol Chem. 2015 May 15;290(20):12929-40. doi: 10.1074/jbc.M115.641829. Epub 2015 Apr 2.

29.

Structure of the V. cholerae Na+-pumping NADH:quinone oxidoreductase.

Steuber J, Vohl G, Casutt MS, Vorburger T, Diederichs K, Fritz G.

Nature. 2014 Dec 4;516(7529):62-7. doi: 10.1038/nature14003.

PMID:
25471880
30.

Coupling of remote alternating-access transport mechanisms for protons and substrates in the multidrug efflux pump AcrB.

Eicher T, Seeger MA, Anselmi C, Zhou W, Brandstätter L, Verrey F, Diederichs K, Faraldo-Gómez JD, Pos KM.

Elife. 2014 Sep 19;3. doi: 10.7554/eLife.03145.

31.

Carboplatin binding to histidine.

Tanley SW, Diederichs K, Kroon-Batenburg LM, Levy C, Schreurs AM, Helliwell JR.

Acta Crystallogr F Struct Biol Commun. 2014 Sep;70(Pt 9):1135-42. doi: 10.1107/S2053230X14016161. Epub 2014 Aug 29. Erratum in: Acta Crystallogr F Struct Biol Commun. 2016 Mar 1;72(Pt 3):251-2.

32.

Crystallization and preliminary analysis of the NqrA and NqrC subunits of the Na+-translocating NADH:ubiquinone oxidoreductase from Vibrio cholerae.

Vohl G, Nedielkov R, Claussen B, Casutt MS, Vorburger T, Diederichs K, Möller HM, Steuber J, Fritz G.

Acta Crystallogr F Struct Biol Commun. 2014 Jul;70(Pt 7):987-92. doi: 10.1107/S2053230X14009881. Epub 2014 Jun 19.

33.

Structure of BamA, an essential factor in outer membrane protein biogenesis.

Albrecht R, Schütz M, Oberhettinger P, Faulstich M, Bermejo I, Rudel T, Diederichs K, Zeth K.

Acta Crystallogr D Biol Crystallogr. 2014 Jun;70(Pt 6):1779-89. doi: 10.1107/S1399004714007482. Epub 2014 May 30.

PMID:
24914988
34.

Crystallization and preliminary X-ray analysis of the C-type lectin domain of the spicule matrix protein SM50 from Strongylocentrotus purpuratus.

Juneja P, Rao A, Cölfen H, Diederichs K, Welte W.

Acta Crystallogr F Struct Biol Commun. 2014 Feb;70(Pt 2):260-2. doi: 10.1107/S2053230X14000880. Epub 2014 Jan 22.

35.

Breaking the indexing ambiguity in serial crystallography.

Brehm W, Diederichs K.

Acta Crystallogr D Biol Crystallogr. 2014 Jan;70(Pt 1):101-9. doi: 10.1107/S1399004713025431. Epub 2013 Dec 24.

PMID:
24419383
36.

Structural insights into DNA replication without hydrogen bonds.

Betz K, Malyshev DA, Lavergne T, Welte W, Diederichs K, Romesberg FE, Marx A.

J Am Chem Soc. 2013 Dec 11;135(49):18637-43. doi: 10.1021/ja409609j. Epub 2013 Nov 27.

37.

Experiences with archived raw diffraction images data: capturing cisplatin after chemical conversion of carboplatin in high salt conditions for a protein crystal.

Tanley SW, Diederichs K, Kroon-Batenburg LM, Schreurs AM, Helliwell JR.

J Synchrotron Radiat. 2013 Nov;20(Pt 6):880-3. doi: 10.1107/S0909049513020724. Epub 2013 Oct 1.

38.

Structure and function of an RNA-reading thermostable DNA polymerase.

Blatter N, Bergen K, Nolte O, Welte W, Diederichs K, Mayer J, Wieland M, Marx A.

Angew Chem Int Ed Engl. 2013 Nov 4;52(45):11935-9. doi: 10.1002/anie.201306655. Epub 2013 Sep 17. No abstract available.

PMID:
24106012
39.

Snapshot of a DNA polymerase while incorporating two consecutive C5-modified nucleotides.

Obeid S, Bußkamp H, Welte W, Diederichs K, Marx A.

J Am Chem Soc. 2013 Oct 23;135(42):15667-9. doi: 10.1021/ja405346s. Epub 2013 Oct 9.

PMID:
24090271
40.

Mechanistic implications for the chorismatase FkbO based on the crystal structure.

Juneja P, Hubrich F, Diederichs K, Welte W, Andexer JN.

J Mol Biol. 2014 Jan 9;426(1):105-15. doi: 10.1016/j.jmb.2013.09.006. Epub 2013 Sep 13.

PMID:
24036425
41.

Crystal structure of Ca2+/H+ antiporter protein YfkE reveals the mechanisms of Ca2+ efflux and its pH regulation.

Wu M, Tong S, Waltersperger S, Diederichs K, Wang M, Zheng L.

Proc Natl Acad Sci U S A. 2013 Jul 9;110(28):11367-72. doi: 10.1073/pnas.1302515110. Epub 2013 Jun 24.

42.

Better models by discarding data?

Diederichs K, Karplus PA.

Acta Crystallogr D Biol Crystallogr. 2013 Jul;69(Pt 7):1215-22. doi: 10.1107/S0907444913001121. Epub 2013 Jun 15.

43.

Structures of KOD and 9°N DNA polymerases complexed with primer template duplex.

Bergen K, Betz K, Welte W, Diederichs K, Marx A.

Chembiochem. 2013 Jun 17;14(9):1058-62. doi: 10.1002/cbic.201300175. Epub 2013 Jun 3.

PMID:
23733496
44.

The three-dimensional structure of TrmB, a transcriptional regulator of dual function in the hyperthermophilic archaeon Pyrococcus furiosus in complex with sucrose.

Krug M, Lee SJ, Boos W, Diederichs K, Welte W.

Protein Sci. 2013 Jun;22(6):800-8. doi: 10.1002/pro.2263. Epub 2013 May 8.

45.

Structural basis of assembly chaperone- mediated snRNP formation.

Grimm C, Chari A, Pelz JP, Kuper J, Kisker C, Diederichs K, Stark H, Schindelin H, Fischer U.

Mol Cell. 2013 Feb 21;49(4):692-703. doi: 10.1016/j.molcel.2012.12.009. Epub 2013 Jan 17.

46.

Structural and functional analysis of the NLRP4 pyrin domain.

Eibl C, Grigoriu S, Hessenberger M, Wenger J, Puehringer S, Pinheiro AS, Wagner RN, Proell M, Reed JC, Page R, Diederichs K, Peti W.

Biochemistry. 2012 Sep 18;51(37):7330-41. doi: 10.1021/bi3007059. Epub 2012 Sep 6.

47.

Interactions of non-polar and "Click-able" nucleotides in the confines of a DNA polymerase active site.

Obeid S, Busskamp H, Welte W, Diederichs K, Marx A.

Chem Commun (Camb). 2012 Aug 28;48(67):8320-2. doi: 10.1039/c2cc34181f. Epub 2012 Jul 6.

PMID:
22766607
48.

KlenTaq polymerase replicates unnatural base pairs by inducing a Watson-Crick geometry.

Betz K, Malyshev DA, Lavergne T, Welte W, Diederichs K, Dwyer TJ, Ordoukhanian P, Romesberg FE, Marx A.

Nat Chem Biol. 2012 Jul;8(7):612-4. doi: 10.1038/nchembio.966. Epub 2012 Jun 3.

49.

Linking crystallographic model and data quality.

Karplus PA, Diederichs K.

Science. 2012 May 25;336(6084):1030-3. doi: 10.1126/science.1218231.

50.

Structures of KlenTaq DNA polymerase caught while incorporating C5-modified pyrimidine and C7-modified 7-deazapurine nucleoside triphosphates.

Bergen K, Steck AL, Strütt S, Baccaro A, Welte W, Diederichs K, Marx A.

J Am Chem Soc. 2012 Jul 25;134(29):11840-3. doi: 10.1021/ja3017889. Epub 2012 Apr 11.

PMID:
22475415

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