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Items: 34


Application of carbon nanotubes in cancer vaccines: Achievements, challenges and chances.

Hassan HAFM, Diebold SS, Smyth LA, Walters AA, Lombardi G, Al-Jamal KT.

J Control Release. 2019 Mar 10;297:79-90. doi: 10.1016/j.jconrel.2019.01.017. Epub 2019 Jan 16. Review.


Macrophages are exploited from an innate wound healing response to facilitate cancer metastasis.

Muliaditan T, Caron J, Okesola M, Opzoomer JW, Kosti P, Georgouli M, Gordon P, Lall S, Kuzeva DM, Pedro L, Shields JD, Gillett CE, Diebold SS, Sanz-Moreno V, Ng T, Hoste E, Arnold JN.

Nat Commun. 2018 Jul 27;9(1):2951. doi: 10.1038/s41467-018-05346-7.


Myosin II Synergizes with F-Actin to Promote DNGR-1-Dependent Cross-Presentation of Dead Cell-Associated Antigens.

Schulz O, Hanč P, Böttcher JP, Hoogeboom R, Diebold SS, Tolar P, Reis E Sousa C.

Cell Rep. 2018 Jul 10;24(2):419-428. doi: 10.1016/j.celrep.2018.06.038.


Repurposing Tin Mesoporphyrin as an Immune Checkpoint Inhibitor Shows Therapeutic Efficacy in Preclinical Models of Cancer.

Muliaditan T, Opzoomer JW, Caron J, Okesola M, Kosti P, Lall S, Van Hemelrijck M, Dazzi F, Tutt A, Grigoriadis A, Gillett CE, Madden SF, Burchell JM, Kordasti S, Diebold SS, Spicer JF, Arnold JN.

Clin Cancer Res. 2018 Apr 1;24(7):1617-1628. doi: 10.1158/1078-0432.CCR-17-2587. Epub 2018 Jan 16.


Interleukin-10 and prostaglandin E2 have complementary but distinct suppressive effects on Toll-like receptor-mediated dendritic cell activation in ovarian carcinoma.

Brencicova E, Jagger AL, Evans HG, Georgouli M, Laios A, Attard Montalto S, Mehra G, Spencer J, Ahmed AA, Raju-Kankipati S, Taams LS, Diebold SS.

PLoS One. 2017 Apr 14;12(4):e0175712. doi: 10.1371/journal.pone.0175712. eCollection 2017.


Antibody-mediated depletion of immunosuppressive factors from ovarian carcinoma-associated ascites for investigation of paracrine versus autocrine effects.

Brencicova E, Diebold SS.

J Immunol Methods. 2017 Apr;443:18-25. doi: 10.1016/j.jim.2017.01.008. Epub 2017 Jan 31.


Dual stimulation of antigen presenting cells using carbon nanotube-based vaccine delivery system for cancer immunotherapy.

Hassan HA, Smyth L, Wang JT, Costa PM, Ratnasothy K, Diebold SS, Lombardi G, Al-Jamal KT.

Biomaterials. 2016 Oct;104:310-22. doi: 10.1016/j.biomaterials.2016.07.005. Epub 2016 Jul 14.


Carbon nanotubes' surface chemistry determines their potency as vaccine nanocarriers in vitro and in vivo.

Hassan HA, Smyth L, Rubio N, Ratnasothy K, Wang JT, Bansal SS, Summers HD, Diebold SS, Lombardi G, Al-Jamal KT.

J Control Release. 2016 Mar 10;225:205-16. doi: 10.1016/j.jconrel.2016.01.030. Epub 2016 Jan 21.


Plant virus particles carrying tumour antigen activate TLR7 and Induce high levels of protective antibody.

Jobsri J, Allen A, Rajagopal D, Shipton M, Kanyuka K, Lomonossoff GP, Ottensmeier C, Diebold SS, Stevenson FK, Savelyeva N.

PLoS One. 2015 Feb 18;10(2):e0118096. doi: 10.1371/journal.pone.0118096. eCollection 2015.


Nucleic acids and endosomal pattern recognition: how to tell friend from foe?

Brencicova E, Diebold SS.

Front Cell Infect Microbiol. 2013 Jul 30;3:37. doi: 10.3389/fcimb.2013.00037. eCollection 2013. Review.


Antibody-antigen-adjuvant conjugates enable co-delivery of antigen and adjuvant to dendritic cells in cis but only have partial targeting specificity.

Kreutz M, Giquel B, Hu Q, Abuknesha R, Uematsu S, Akira S, Nestle FO, Diebold SS.

PLoS One. 2012;7(7):e40208. doi: 10.1371/journal.pone.0040208. Epub 2012 Jul 10.


Monitoring of in vivo function of superparamagnetic iron oxide labelled murine dendritic cells during anti-tumour vaccination.

Tavaré R, Sagoo P, Varama G, Tanriver Y, Warely A, Diebold SS, Southworth R, Schaeffter T, Lechler RI, Razavi R, Lombardi G, Mullen GE.

PLoS One. 2011;6(5):e19662. doi: 10.1371/journal.pone.0019662. Epub 2011 May 27.


Plasmacytoid dendritic cell-derived type I interferon is crucial for the adjuvant activity of Toll-like receptor 7 agonists.

Rajagopal D, Paturel C, Morel Y, Uematsu S, Akira S, Diebold SS.

Blood. 2010 Mar 11;115(10):1949-57. doi: 10.1182/blood-2009-08-238543. Epub 2010 Jan 11.


PolyI:C-induced reduction in uptake of soluble antigen is independent of dendritic cell activation.

Tirapu I, Giquel B, Alexopoulou L, Uematsu S, Flavell R, Akira S, Diebold SS.

Int Immunol. 2009 Jul;21(7):871-9. doi: 10.1093/intimm/dxp053. Epub 2009 Jun 7.


Role of TLR3 in the immunogenicity of replicon plasmid-based vaccines.

Diebold SS, Schulz O, Alexopoulou L, Leitner WW, Flavell RA, Reis e Sousa C.

Gene Ther. 2009 Mar;16(3):359-66. doi: 10.1038/gt.2008.164. Epub 2008 Dec 4.


Activation of dendritic cells by toll-like receptors and C-type lectins.

Diebold SS.

Handb Exp Pharmacol. 2009;(188):3-30. doi: 10.1007/978-3-540-71029-5_1. Review.


Freeze-and-thaw-disrupted tumour cells impair the responsiveness of DC to TLR stimulation.

Tirapu I, Lewis A, Kreutz M, McLinden H, Diebold SS.

Eur J Immunol. 2008 Oct;38(10):2740-50. doi: 10.1002/eji.200838284.


Determination of T-cell fate by dendritic cells.

Diebold SS.

Immunol Cell Biol. 2008 Jul;86(5):389-97. doi: 10.1038/icb.2008.26. Epub 2008 Apr 1. Review.


Recognition of viral single-stranded RNA by Toll-like receptors.

Diebold SS.

Adv Drug Deliv Rev. 2008 Apr 29;60(7):813-23. doi: 10.1016/j.addr.2007.11.004. Epub 2007 Dec 27. Review.


Nucleic acid agonists for Toll-like receptor 7 are defined by the presence of uridine ribonucleotides.

Diebold SS, Massacrier C, Akira S, Paturel C, Morel Y, Reis e Sousa C.

Eur J Immunol. 2006 Dec;36(12):3256-67.


Tubulovesicular structures within vesicular stomatitis virus G protein-pseudotyped lentiviral vector preparations carry DNA and stimulate antiviral responses via Toll-like receptor 9.

Pichlmair A, Diebold SS, Gschmeissner S, Takeuchi Y, Ikeda Y, Collins MK, Reis e Sousa C.

J Virol. 2007 Jan;81(2):539-47. Epub 2006 Nov 1.


Toll-like receptor 3 promotes cross-priming to virus-infected cells.

Schulz O, Diebold SS, Chen M, Näslund TI, Nolte MA, Alexopoulou L, Azuma YT, Flavell RA, Liljeström P, Reis e Sousa C.

Nature. 2005 Feb 24;433(7028):887-92. Epub 2005 Feb 13.


Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA.

Diebold SS, Kaisho T, Hemmi H, Akira S, Reis e Sousa C.

Science. 2004 Mar 5;303(5663):1529-31. Epub 2004 Feb 19.


Viral infection switches non-plasmacytoid dendritic cells into high interferon producers.

Diebold SS, Montoya M, Unger H, Alexopoulou L, Roy P, Haswell LE, Al-Shamkhani A, Flavell R, Borrow P, Reis e Sousa C.

Nature. 2003 Jul 17;424(6946):324-8. Epub 2003 Jun 22.


Mannose receptor-mediated gene delivery into antigen presenting dendritic cells.

Diebold SS, Plank C, Cotten M, Wagner E, Zenke M.

Somat Cell Mol Genet. 2002 Nov;27(1-6):65-74. Review.


Toll-like receptor expression in murine DC subsets: lack of TLR7 expression by CD8 alpha+ DC correlates with unresponsiveness to imidazoquinolines.

Edwards AD, Diebold SS, Slack EM, Tomizawa H, Hemmi H, Kaisho T, Akira S, Reis e Sousa C.

Eur J Immunol. 2003 Apr;33(4):827-33.


Microbial recognition via Toll-like receptor-dependent and -independent pathways determines the cytokine response of murine dendritic cell subsets to CD40 triggering.

Edwards AD, Manickasingham SP, Spörri R, Diebold SS, Schulz O, Sher A, Kaisho T, Akira S, Reis e Sousa C.

J Immunol. 2002 Oct 1;169(7):3652-60.


The impact of c-met/scatter factor receptor on dendritic cell migration.

Kurz SM, Diebold SS, Hieronymus T, Gust TC, Bartunek P, Sachs M, Birchmeier W, Zenke M.

Eur J Immunol. 2002 Jul;32(7):1832-8.


MHC class II presentation of endogenously expressed antigens by transfected dendritic cells.

Diebold SS, Cotten M, Koch N, Zenke M.

Gene Ther. 2001 Mar;8(6):487-93.


Mannose polyethylenimine conjugates for targeted DNA delivery into dendritic cells.

Diebold SS, Kursa M, Wagner E, Cotten M, Zenke M.

J Biol Chem. 1999 Jul 2;274(27):19087-94.


Polarised expression pattern of focal contact proteins in highly motile antigen presenting dendritic cells.

Madruga J, Koritschoner NP, Diebold SS, Kurz SM, Zenke M.

J Cell Sci. 1999 Jun;112 ( Pt 11):1685-96.


Efficient gene delivery into human dendritic cells by adenovirus polyethylenimine and mannose polyethylenimine transfection.

Diebold SS, Lehrmann H, Kursa M, Wagner E, Cotten M, Zenke M.

Hum Gene Ther. 1999 Mar 20;10(5):775-86.


Gene-modified dendritic cells by receptor-mediated transfection.

Diebold SS, Cotten M, Wagner E, Zenke M.

Adv Exp Med Biol. 1998;451:449-55. No abstract available.


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