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Items: 25

1.
2.
3.

Targeting Alzheimer's Disease Neuro-Metabolic Dysfunction with a Small Molecule Nuclear Receptor Agonist (T3D-959) Reverses Disease Pathologies.

Tong M, Dominguez C, Didsbury J, de la Monte SM.

J Alzheimers Dis Parkinsonism. 2016 Jun;6(3). pii: 238. Epub 2016 Jun 3.

4.

T3D-959: A Multi-Faceted Disease Remedial Drug Candidate for the Treatment of Alzheimer's Disease.

Tong M, Deochand C, Didsbury J, de la Monte SM.

J Alzheimers Dis. 2016;51(1):123-38. doi: 10.3233/JAD-151013.

5.

NF-kappaB activation provides the potential link between inflammation and hyperplasia in the arthritic joint.

Miagkov AV, Kovalenko DV, Brown CE, Didsbury JR, Cogswell JP, Stimpson SA, Baldwin AS, Makarov SS.

Proc Natl Acad Sci U S A. 1998 Nov 10;95(23):13859-64.

6.

Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-alpha.

Moss ML, Jin SL, Milla ME, Bickett DM, Burkhart W, Carter HL, Chen WJ, Clay WC, Didsbury JR, Hassler D, Hoffman CR, Kost TA, Lambert MH, Leesnitzer MA, McCauley P, McGeehan G, Mitchell J, Moyer M, Pahel G, Rocque W, Overton LK, Schoenen F, Seaton T, Su JL, Becherer JD, et al.

Nature. 1997 Feb 20;385(6618):733-6. Erratum in: Nature 1997 Apr 17;386(6626):738.

PMID:
9034191
7.

Cross-desensitization of receptors for peptide chemoattractants. Characterization of a new form of leukocyte regulation.

Tomhave ED, Richardson RM, Didsbury JR, Menard L, Snyderman R, Ali H.

J Immunol. 1994 Oct 1;153(7):3267-75.

PMID:
8089498
8.

Differences in phosphorylation of formylpeptide and C5a chemoattractant receptors correlate with differences in desensitization.

Ali H, Richardson RM, Tomhave ED, Didsbury JR, Snyderman R.

J Biol Chem. 1993 Nov 15;268(32):24247-54.

9.

Rac1, a low-molecular-mass GTP-binding-protein with high intrinsic GTPase activity and distinct biochemical properties.

Ménard L, Tomhave E, Casey PJ, Uhing RJ, Snyderman R, Didsbury JR.

Eur J Biochem. 1992 Jun 1;206(2):537-46.

10.

Purification and characterization of an ADP-ribosyltransferase produced by Clostridium limosum.

Just I, Mohr C, Schallehn G, Menard L, Didsbury JR, Vandekerckhove J, van Damme J, Aktories K.

J Biol Chem. 1992 May 25;267(15):10274-80.

11.

Differential regulation of cAMP by endogenous versus transfected formylpeptide chemoattractant receptors: implications for Gi-coupled receptor signaling.

Uhing RJ, Gettys TW, Tomhave E, Snyderman R, Didsbury JR.

Biochem Biophys Res Commun. 1992 Mar 31;183(3):1033-9.

PMID:
1314571
12.

Functional high efficiency expression of cloned leukocyte chemoattractant receptor cDNAs.

Didsbury JR, Uhing RJ, Tomhave E, Gerard C, Gerard N, Snyderman R.

FEBS Lett. 1992 Feb 10;297(3):275-9.

13.

Both stimulatory and inhibitory GDP/GTP exchange proteins, smg GDS and rho GDI, are active on multiple small GTP-binding proteins.

Hiraoka K, Kaibuchi K, Ando S, Musha T, Takaishi K, Mizuno T, Asada M, Ménard L, Tomhave E, Didsbury J, et al.

Biochem Biophys Res Commun. 1992 Jan 31;182(2):921-30.

PMID:
1734890
14.

Receptor class desensitization of leukocyte chemoattractant receptors.

Didsbury JR, Uhing RJ, Tomhave E, Gerard C, Gerard N, Snyderman R.

Proc Natl Acad Sci U S A. 1991 Dec 15;88(24):11564-8.

15.

Molecular mechanisms of leukocyte activation by chemoattractants.

Snyderman R, Didsbury J.

Agents Actions Suppl. 1991;35:3-8. Review.

PMID:
1664188
16.

Isoprenylation of the low molecular mass GTP-binding proteins rac 1 and rac 2: possible role in membrane localization.

Didsbury JR, Uhing RJ, Snyderman R.

Biochem Biophys Res Commun. 1990 Sep 14;171(2):804-12.

PMID:
2119580
18.

rac, a novel ras-related family of proteins that are botulinum toxin substrates.

Didsbury J, Weber RF, Bokoch GM, Evans T, Snyderman R.

J Biol Chem. 1989 Oct 5;264(28):16378-82.

19.

Identification of the ral and rac1 gene products, low molecular mass GTP-binding proteins from human platelets.

Polakis PG, Weber RF, Nevins B, Didsbury JR, Evans T, Snyderman R.

J Biol Chem. 1989 Oct 5;264(28):16383-9.

20.
22.

Human Gi protein alpha-subunit: deduction of amino acid structure from a cloned cDNA.

Didsbury JR, Ho YS, Snyderman R.

FEBS Lett. 1987 Jan 26;211(2):160-4.

23.

Molecular cloning of a novel human GTP-binding protein and its potential role in chemoattractant stimulus-response coupling.

Didsbury JR, Snyderman R.

Trans Assoc Am Physicians. 1987;100:99-108. No abstract available.

PMID:
3137710
25.

Binding and uptake of diphtheria toxin by toxin-resistant Chinese hamster ovary and mouse cells.

Didsbury JR, Moehring JM, Moehring TJ.

Mol Cell Biol. 1983 Jul;3(7):1283-94.

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