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Items: 1 to 50 of 112

1.

1,2,4-Triazole-3-thione Compounds as Inhibitors of Dizinc Metallo-β-lactamases.

Sevaille L, Gavara L, Bebrone C, De Luca F, Nauton L, Achard M, Mercuri P, Tanfoni S, Borgianni L, Guyon C, Lonjon P, Turan-Zitouni G, Dzieciolowski J, Becker K, Bénard L, Condon C, Maillard L, Martinez J, Frère JM, Dideberg O, Galleni M, Docquier JD, Hernandez JF.

ChemMedChem. 2017 Jun 21;12(12):972-985. doi: 10.1002/cmdc.201700186. Epub 2017 Jun 12.

PMID:
28505394
2.

The Inactivation of a New Peptidoglycan Hydrolase Pmp23 Leads to Abnormal Septum Formation in Streptococcus pneumoniae.

E P, B D, C F, O D, T V, Am DG.

Open Microbiol J. 2008;2:107-14. doi: 10.2174/1874285800802010107. Epub 2008 Aug 22.

3.

Structural basis for the broad-spectrum inhibition of metallo-beta-lactamases by thiols.

Liénard BM, Garau G, Horsfall L, Karsisiotis AI, Damblon C, Lassaux P, Papamicael C, Roberts GC, Galleni M, Dideberg O, Frère JM, Schofield CJ.

Org Biomol Chem. 2008 Jul 7;6(13):2282-94. doi: 10.1039/b802311e. Epub 2008 May 7.

PMID:
18563261
4.

Mutational analysis of the zinc- and substrate-binding sites in the CphA metallo-beta-lactamase from Aeromonas hydrophila.

Bebrone C, Anne C, Kerff F, Garau G, De Vriendt K, Lantin R, Devreese B, Van Beeumen J, Dideberg O, Frère JM, Galleni M.

Biochem J. 2008 Aug 15;414(1):151-9. doi: 10.1042/BJ20080375.

5.

Trapping of an acyl-enzyme intermediate in a penicillin-binding protein (PBP)-catalyzed reaction.

Macheboeuf P, Lemaire D, Teller N, Martins Ados S, Luxen A, Dideberg O, Jamin M, Dessen A.

J Mol Biol. 2008 Feb 15;376(2):405-13. Epub 2007 Nov 1. Erratum in: J Mol Biol. 2008 Aug 1;381(1):248. Teller, Nathalie [added]; Luxen, André [added].

PMID:
18155726
6.

The three-dimensional structure of VIM-2, a Zn-beta-lactamase from Pseudomonas aeruginosa in its reduced and oxidised form.

Garcia-Saez I, Docquier JD, Rossolini GM, Dideberg O.

J Mol Biol. 2008 Jan 18;375(3):604-11. Epub 2007 Nov 13.

PMID:
18061205
7.

Structural insights into the design of inhibitors for the L1 metallo-beta-lactamase from Stenotrophomonas maltophilia.

Nauton L, Kahn R, Garau G, Hernandez JF, Dideberg O.

J Mol Biol. 2008 Jan 4;375(1):257-69. Epub 2007 Oct 22.

PMID:
17999929
8.

Structure-based design of small peptide inhibitors of protein kinase CK2 subunit interaction.

Laudet B, Barette C, Dulery V, Renaudet O, Dumy P, Metz A, Prudent R, Deshiere A, Dideberg O, Filhol O, Cochet C.

Biochem J. 2007 Dec 15;408(3):363-73.

9.

Competitive inhibitors of the CphA metallo-beta-lactamase from Aeromonas hydrophila.

Horsfall LE, Garau G, Liénard BM, Dideberg O, Schofield CJ, Frère JM, Galleni M.

Antimicrob Agents Chemother. 2007 Jun;51(6):2136-42. Epub 2007 Feb 16.

10.

Penicillin binding proteins: key players in bacterial cell cycle and drug resistance processes.

Macheboeuf P, Contreras-Martel C, Job V, Dideberg O, Dessen A.

FEMS Microbiol Rev. 2006 Sep;30(5):673-91. Review.

11.

Crystal structure of penicillin-binding protein 1a (PBP1a) reveals a mutational hotspot implicated in beta-lactam resistance in Streptococcus pneumoniae.

Contreras-Martel C, Job V, Di Guilmi AM, Vernet T, Dideberg O, Dessen A.

J Mol Biol. 2006 Jan 27;355(4):684-96. Epub 2005 Nov 9.

PMID:
16316661
12.

Identical penicillin-binding domains in penicillin-binding proteins of Streptococcus pneumoniae clinical isolates with different levels of beta-lactam resistance.

Chesnel L, Carapito R, Croizé J, Dideberg O, Vernet T, Zapun A.

Antimicrob Agents Chemother. 2005 Jul;49(7):2895-902.

14.

Is it necessary to change the classification of {beta}-lactamases?

Frère JM, Galleni M, Bush K, Dideberg O.

J Antimicrob Chemother. 2005 Jun;55(6):1051-3. Epub 2005 May 10. No abstract available.

15.
16.

In vitro reconstitution of a trimeric complex of DivIB, DivIC and FtsL, and their transient co-localization at the division site in Streptococcus pneumoniae.

Noirclerc-Savoye M, Le Gouëllec A, Morlot C, Dideberg O, Vernet T, Zapun A.

Mol Microbiol. 2005 Jan;55(2):413-24.

17.

Active site restructuring regulates ligand recognition in class A penicillin-binding proteins.

Macheboeuf P, Di Guilmi AM, Job V, Vernet T, Dideberg O, Dessen A.

Proc Natl Acad Sci U S A. 2005 Jan 18;102(3):577-82. Epub 2005 Jan 6.

18.

Crystal structure of a peptidoglycan synthesis regulatory factor (PBP3) from Streptococcus pneumoniae.

Morlot C, Pernot L, Le Gouellec A, Di Guilmi AM, Vernet T, Dideberg O, Dessen A.

J Biol Chem. 2005 Apr 22;280(16):15984-91. Epub 2004 Dec 13.

19.

A metallo-beta-lactamase enzyme in action: crystal structures of the monozinc carbapenemase CphA and its complex with biapenem.

Garau G, Bebrone C, Anne C, Galleni M, Frère JM, Dideberg O.

J Mol Biol. 2005 Jan 28;345(4):785-95.

20.

Crystal structure of human otubain 2.

Nanao MH, Tcherniuk SO, Chroboczek J, Dideberg O, Dessen A, Balakirev MY.

EMBO Rep. 2004 Aug;5(8):783-8. Epub 2004 Jul 16.

21.

Update of the standard numbering scheme for class B beta-lactamases.

Garau G, García-Sáez I, Bebrone C, Anne C, Mercuri P, Galleni M, Frère JM, Dideberg O.

Antimicrob Agents Chemother. 2004 Jul;48(7):2347-9. No abstract available.

22.

Probing the specificity of the subclass B3 FEZ-1 metallo-beta-lactamase by site-directed mutagenesis.

Mercuri PS, García-Sáez I, De Vriendt K, Thamm I, Devreese B, Van Beeumen J, Dideberg O, Rossolini GM, Frère JM, Galleni M.

J Biol Chem. 2004 Aug 6;279(32):33630-8. Epub 2004 May 24.

23.

Biochemical characterization of Streptococcus pneumoniae penicillin-binding protein 2b and its implication in beta-lactam resistance.

Pagliero E, Chesnel L, Hopkins J, Croizé J, Dideberg O, Vernet T, Di Guilmi AM.

Antimicrob Agents Chemother. 2004 May;48(5):1848-55.

24.

The D,D-carboxypeptidase PBP3 organizes the division process of Streptococcus pneumoniae.

Morlot C, Noirclerc-Savoye M, Zapun A, Dideberg O, Vernet T.

Mol Microbiol. 2004 Mar;51(6):1641-8.

25.

A PBP2x from a clinical isolate of Streptococcus pneumoniae exhibits an alternative mechanism for reduction of susceptibility to beta-lactam antibiotics.

Pernot L, Chesnel L, Le Gouellec A, Croizé J, Vernet T, Dideberg O, Dessen A.

J Biol Chem. 2004 Apr 16;279(16):16463-70. Epub 2004 Jan 20.

26.

The structural bases of the processive degradation of iota-carrageenan, a main cell wall polysaccharide of red algae.

Michel G, Helbert W, Kahn R, Dideberg O, Kloareg B.

J Mol Biol. 2003 Nov 28;334(3):421-33.

PMID:
14623184
27.
28.
29.

The structural modifications induced by the M339F substitution in PBP2x from Streptococcus pneumoniae further decreases the susceptibility to beta-lactams of resistant strains.

Chesnel L, Pernot L, Lemaire D, Champelovier D, Croizé J, Dideberg O, Vernet T, Zapun A.

J Biol Chem. 2003 Nov 7;278(45):44448-56. Epub 2003 Aug 15.

30.
31.

Structural studies of the transpeptidase domain of PBP1a from Streptococcus pneumoniae.

Job V, Di Guilmi AM, Martin L, Vernet T, Dideberg O, Dessen A.

Acta Crystallogr D Biol Crystallogr. 2003 Jun;59(Pt 6):1067-9. Epub 2003 May 23.

PMID:
12777776
32.

The 1.5-A structure of Chryseobacterium meningosepticum zinc beta-lactamase in complex with the inhibitor, D-captopril.

García-Saez I, Hopkins J, Papamicael C, Franceschini N, Amicosante G, Rossolini GM, Galleni M, Frère JM, Dideberg O.

J Biol Chem. 2003 Jun 27;278(26):23868-73. Epub 2003 Apr 8.

33.

Functional characterization of penicillin-binding protein 1b from Streptococcus pneumoniae.

Di Guilmi AM, Dessen A, Dideberg O, Vernet T.

J Bacteriol. 2003 Mar;185(5):1650-8.

34.

Three-dimensional structure of FEZ-1, a monomeric subclass B3 metallo-beta-lactamase from Fluoribacter gormanii, in native form and in complex with D-captopril.

García-Sáez I, Mercuri PS, Papamicael C, Kahn R, Frère JM, Galleni M, Rossolini GM, Dideberg O.

J Mol Biol. 2003 Jan 24;325(4):651-60.

PMID:
12507470
35.

Molecular mechanisms of antibiotic resistance in gram-positive pathogens.

Dessen A, Di Guilmi AM, Vernet T, Dideberg O.

Curr Drug Targets Infect Disord. 2001 May;1(1):63-77. Review.

PMID:
12455234
36.

Bifunctional penicillin-binding proteins: focus on the glycosyltransferase domain and its specific inhibitor moenomycin.

Di Guilmi AM, Dessen A, Dideberg O, Vernet T.

Curr Pharm Biotechnol. 2002 Jun;3(2):63-75. Review.

PMID:
12022260
37.
38.

Evidence of a functional requirement for a carbamoylated lysine residue in MurD, MurE and MurF synthetases as established by chemical rescue experiments.

Dementin S, Bouhss A, Auger G, Parquet C, Mengin-Lecreulx D, Dideberg O, van Heijenoort J, Blanot D.

Eur J Biochem. 2001 Nov;268(22):5800-7.

39.

Crystal structure of PBP2x from a highly penicillin-resistant Streptococcus pneumoniae clinical isolate: a mosaic framework containing 83 mutations.

Dessen A, Mouz N, Gordon E, Hopkins J, Dideberg O.

J Biol Chem. 2001 Nov 30;276(48):45106-12. Epub 2001 Sep 11.

40.

The iota-carrageenase of Alteromonas fortis. A beta-helix fold-containing enzyme for the degradation of a highly polyanionic polysaccharide.

Michel G, Chantalat L, Fanchon E, Henrissat B, Kloareg B, Dideberg O.

J Biol Chem. 2001 Oct 26;276(43):40202-9. Epub 2001 Aug 7.

41.

The kappa-carrageenase of P. carrageenovora features a tunnel-shaped active site: a novel insight in the evolution of Clan-B glycoside hydrolases.

Michel G, Chantalat L, Duee E, Barbeyron T, Henrissat B, Kloareg B, Dideberg O.

Structure. 2001 Jun;9(6):513-25.

42.

Standard numbering scheme for class B beta-lactamases.

Galleni M, Lamotte-Brasseur J, Rossolini GM, Spencer J, Dideberg O, Frère JM; Metallo-beta-lactamases Working Group.

Antimicrob Agents Chemother. 2001 Mar;45(3):660-3. No abstract available.

43.

Crystal structure of UDP-N-acetylmuramoyl-L-alanyl-D-glutamate: meso-diaminopimelate ligase from Escherichia coli.

Gordon E, Flouret B, Chantalat L, van Heijenoort J, Mengin-Lecreulx D, Dideberg O.

J Biol Chem. 2001 Apr 6;276(14):10999-1006. Epub 2000 Dec 20.

44.

"Open" structures of MurD: domain movements and structural similarities with folylpolyglutamate synthetase.

Bertrand JA, Fanchon E, Martin L, Chantalat L, Auger G, Blanot D, van Heijenoort J, Dideberg O.

J Mol Biol. 2000 Sep 1;301(5):1257-66.

PMID:
10966819
45.
46.

Crystal structure of human survivin reveals a bow tie-shaped dimer with two unusual alpha-helical extensions.

Chantalat L, Skoufias DA, Kleman JP, Jung B, Dideberg O, Margolis RL.

Mol Cell. 2000 Jul;6(1):183-9.

47.

Structural effects of the active site mutation cysteine to serine in Bacillus cereus zinc-beta-lactamase.

Chantalat L, Duée E, Galleni M, Frère JM, Dideberg O.

Protein Sci. 2000 Jul;9(7):1402-6.

48.
49.

Expression, purification, crystallization and preliminary X-ray analysis of the iota-carrageenase from Alteromonas fortis.

Michel G, Flament D, Barbeyron T, Vernet T, Kloareg B, Dideberg O.

Acta Crystallogr D Biol Crystallogr. 2000 Jun;56(Pt 6):766-8.

PMID:
10818359
50.

Preference of Cd(II) and Zn(II) for the two metal sites in Bacillus cereus beta-lactamase II: A perturbed angular correlation of gamma-rays spectroscopic study.

Paul-Soto R, Zeppezauer M, Adolph HW, Galleni M, Frere JM, Carfi A, Dideberg O, Wouters J, Hemmingsen L, Bauer R.

Biochemistry. 1999 Dec 14;38(50):16500-6.

PMID:
10600111

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