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Items: 1 to 50 of 144

1.

Inducible epithelial resistance against acute Sendai virus infection prevents chronic asthma-like lung disease in mice.

Goldblatt DL, Flores JR, Valverde Ha G, Jaramillo AM, Tkachman S, Kirkpatrick CT, Wali S, Hernandez B, Ost DE, Scott BL, Chen J, Evans SE, Tuvim MJ, Dickey BF.

Br J Pharmacol. 2020 Jan 22. doi: 10.1111/bph.14977. [Epub ahead of print]

PMID:
31968123
2.

ILC2s mediate systemic innate protection by priming mucus production at distal mucosal sites.

Campbell L, Hepworth MR, Whittingham-Dowd J, Thompson S, Bancroft AJ, Hayes KS, Shaw TN, Dickey BF, Flamar AL, Artis D, Schwartz DA, Evans CM, Roberts IS, Thornton DJ, Grencis RK.

J Exp Med. 2019 Dec 2;216(12):2714-2723. doi: 10.1084/jem.20180610. Epub 2019 Oct 3.

3.

Refinement of estimates of mortality risk using the Radiologic Severity Index in hematologic malignancy patients with respiratory syncytial virus infection.

Sheshadri A, Karimipour M, Vakil E, Bashoura L, Godoy M, Arain MH, Evans SE, Dickey BF, Ost DE, Chemaly RF, Faiz SA.

Transpl Infect Dis. 2019 Aug;21(4):e13105. doi: 10.1111/tid.13105. Epub 2019 May 28.

PMID:
31081570
4.

Erratum for Kirkpatrick et al., "Inducible Lung Epithelial Resistance Requires Multisource Reactive Oxygen Species Generation To Protect against Viral Infections".

Kirkpatrick CT, Wang Y, Leiva Juarez MM, Shivshankar P, Pantaleón García J, Plumer AK, Kulkarni VV, Ware HH, Gulraiz F, Chavez Cavasos MA, Martinez Zayas G, Wali S, Rice AP, Liu H, Tour JM, Sikkema WKA, Cruz Solbes AS, Youker KA, Tuvim MJ, Dickey BF, Evans SE.

mBio. 2019 Apr 2;10(2). pii: e00496-19. doi: 10.1128/mBio.00496-19. No abstract available.

5.

Lipocalin-2 is dispensable in inflammation-induced sickness and depression-like behavior.

Vichaya EG, Gross PS, Estrada DJ, Cole SW, Grossberg AJ, Evans SE, Tuvim MJ, Dickey BF, Dantzer R.

Psychopharmacology (Berl). 2019 Oct;236(10):2975-2982. doi: 10.1007/s00213-019-05190-7. Epub 2019 Feb 26.

PMID:
30806746
6.

Different Munc18 proteins mediate baseline and stimulated airway mucin secretion.

Jaramillo AM, Piccotti L, Velasco WV, Delgado ASH, Azzegagh Z, Chung F, Nazeer U, Farooq J, Brenner J, Parker-Thornburg J, Scott BL, Evans CM, Adachi R, Burns AR, Kreda SM, Tuvim MJ, Dickey BF.

JCI Insight. 2019 Mar 21;4(6). pii: 124815. doi: 10.1172/jci.insight.124815. eCollection 2019 Mar 21.

7.

Pulmonary Impairment after Respiratory Viral Infections Is Associated with High Mortality in Allogeneic Hematopoietic Cell Transplant Recipients.

Sheshadri A, Chemaly RF, Alousi AM, Shah PK, Rondon G, Bashoura L, Kmeid J, Azzi J, Blanco DW, Kaous M, Dickey BF, Champlin RE, Shah DP.

Biol Blood Marrow Transplant. 2019 Apr;25(4):800-809. doi: 10.1016/j.bbmt.2018.11.022. Epub 2018 Dec 3.

PMID:
30521974
8.

What it takes for a cough to expel mucus from the airway.

Dickey BF.

Proc Natl Acad Sci U S A. 2018 Dec 4;115(49):12340-12342. doi: 10.1073/pnas.1817484115. Epub 2018 Nov 20. No abstract available.

9.

Chair's Summary: Secreted Mucins in Lung Diseases.

Dickey BF.

Ann Am Thorac Soc. 2018 Nov;15(Suppl 3):S140-S142. doi: 10.1513/AnnalsATS.201810-666AW. No abstract available.

10.

Airway Mucin Secretion.

Jaramillo AM, Azzegagh Z, Tuvim MJ, Dickey BF.

Ann Am Thorac Soc. 2018 Nov;15(Suppl 3):S164-S170. doi: 10.1513/AnnalsATS.201806-371AW. Review.

11.

Inflammation-induced upregulation of P2X4 expression augments mucin secretion in airway epithelia.

Winkelmann VE, Thompson KE, Neuland K, Jaramillo AM, Fois G, Schmidt H, Wittekindt OH, Han W, Tuvim MJ, Dickey BF, Dietl P, Frick M.

Am J Physiol Lung Cell Mol Physiol. 2019 Jan 1;316(1):L58-L70. doi: 10.1152/ajplung.00157.2018. Epub 2018 Oct 25.

12.

MyD88 controls airway epithelial Muc5ac expression during TLR activation conditions from agricultural organic dust exposure.

Dickinson JD, Sweeter JM, Staab EB, Nelson AJ, Bailey KL, Warren KJ, Jaramillo AM, Dickey BF, Poole JA.

Am J Physiol Lung Cell Mol Physiol. 2019 Feb 1;316(2):L334-L347. doi: 10.1152/ajplung.00206.2018. Epub 2018 Oct 25.

PMID:
30358438
13.

Dawn of a New Era in the Diagnosis and Treatment of Airway Mucus Dysfunction.

Kim V, Evans CM, Dickey BF.

Am J Respir Crit Care Med. 2019 Jan 15;199(2):133-134. doi: 10.1164/rccm.201808-1444ED. No abstract available.

PMID:
30252497
14.

COPD-Type lung inflammation promotes K-ras mutant lung cancer through epithelial HIF-1α mediated tumor angiogenesis and proliferation.

De la Garza MM, Cumpian AM, Daliri S, Castro-Pando S, Umer M, Gong L, Khosravi N, Caetano MS, Ramos-Castañeda M, Flores AG, Beltran EC, Tran HT, Tuvim MJ, Ostrin EJ, Dickey BF, Evans CM, Moghaddam SJ.

Oncotarget. 2018 Aug 31;9(68):32972-32983. doi: 10.18632/oncotarget.26030. eCollection 2018 Aug 31.

15.

Requirement for MUC5AC in KRAS-dependent lung carcinogenesis.

Bauer AK, Umer M, Richardson VL, Cumpian AM, Harder AQ, Khosravi N, Azzegagh Z, Hara NM, Ehre C, Mohebnasab M, Caetano MS, Merrick DT, van Bokhoven A, Wistuba II, Kadara H, Dickey BF, Velmurugan K, Mann PR, Lu X, Barón AE, Evans CM, Moghaddam SJ.

JCI Insight. 2018 Aug 9;3(15). pii: 120941. doi: 10.1172/jci.insight.120941. eCollection 2018 Aug 9.

16.

Progression of the Radiologic Severity Index predicts mortality in patients with parainfluenza virus-associated lower respiratory infections.

Sheshadri A, Shah DP, Godoy M, Erasmus JJ, Song J, Li L, Evans SE, Chemaly RF, Dickey BF, Ost DE.

PLoS One. 2018 May 17;13(5):e0197418. doi: 10.1371/journal.pone.0197418. eCollection 2018.

17.

Inducible Lung Epithelial Resistance Requires Multisource Reactive Oxygen Species Generation To Protect against Viral Infections.

Kirkpatrick CT, Wang Y, Leiva Juarez MM, Shivshankar P, Pantaleón García J, Plumer AK, Kulkarni VV, Ware HH, Gulraiz F, Chavez Cavasos MA, Martinez Zayas G, Wali S, Rice AP, Liu H, Tour JM, Sikkema WKA, Cruz Solbes AS, Youker KA, Tuvim MJ, Dickey BF, Evans SE.

mBio. 2018 May 15;9(3). pii: e00696-18. doi: 10.1128/mBio.00696-18. Erratum in: MBio. 2019 Apr 2;10(2):. Martinez Zayes, Gabriela [corrected to Martinez Zayas, Gabriela].

18.

Munc18-2, but not Munc18-1 or Munc18-3, controls compound and single-vesicle-regulated exocytosis in mast cells.

Gutierrez BA, Chavez MA, Rodarte AI, Ramos MA, Dominguez A, Petrova Y, Davalos AJ, Costa RM, Elizondo R, Tuvim MJ, Dickey BF, Burns AR, Heidelberger R, Adachi R.

J Biol Chem. 2018 May 11;293(19):7148-7159. doi: 10.1074/jbc.RA118.002455. Epub 2018 Mar 29.

19.

E-Cigarettes: Mucus Measurements Make Marks.

Evans CM, Dickey BF, Schwartz DA.

Am J Respir Crit Care Med. 2018 Feb 15;197(4):420-422. doi: 10.1164/rccm.201711-2157ED. No abstract available.

20.

Munc13 proteins control regulated exocytosis in mast cells.

Rodarte EM, Ramos MA, Davalos AJ, Moreira DC, Moreno DS, Cardenas EI, Rodarte AI, Petrova Y, Molina S, Rendon LE, Sanchez E, Breaux K, Tortoriello A, Manllo J, Gonzalez EA, Tuvim MJ, Dickey BF, Burns AR, Heidelberger R, Adachi R.

J Biol Chem. 2018 Jan 5;293(1):345-358. doi: 10.1074/jbc.M117.816884. Epub 2017 Nov 15.

21.

β2-Adrenoceptor signaling in airway epithelial cells promotes eosinophilic inflammation, mucous metaplasia, and airway contractility.

Nguyen LP, Al-Sawalha NA, Parra S, Pokkunuri I, Omoluabi O, Okulate AA, Windham Li E, Hazen M, Gonzalez-Granado JM, Daly CJ, McGrath JC, Tuvim MJ, Knoll BJ, Dickey BF, Bond RA.

Proc Natl Acad Sci U S A. 2017 Oct 24;114(43):E9163-E9171. doi: 10.1073/pnas.1710196114. Epub 2017 Oct 9.

22.

Combined aerosolized Toll-like receptor ligands are an effective therapeutic agent against influenza pneumonia when co-administered with oseltamivir.

Leiva-Juarez MM, Kirkpatrick CT, Gilbert BE, Scott B, Tuvim MJ, Dickey BF, Evans SE, Markesich D.

Eur J Pharmacol. 2018 Jan 5;818:191-197. doi: 10.1016/j.ejphar.2017.10.035. Epub 2017 Oct 21.

23.

Understanding Interstitial Lung Disease: It's in the Mucus.

Dickey BF, Whitsett JA.

Am J Respir Cell Mol Biol. 2017 Jul;57(1):12-14. doi: 10.1165/rcmb.2017-0116ED. No abstract available.

24.

Measuring Airway Mucin 2 in Patients with Severe Chronic Obstructive Pulmonary Disease with Bacterial Colonization.

Dickey BF, Fahy JV, Kesimer M, Boucher RC, Evans CM, Thornton D.

Ann Am Thorac Soc. 2016 Nov;13(11):2103-2104. No abstract available.

25.

SNAP23 is selectively expressed in airway secretory cells and mediates baseline and stimulated mucin secretion.

Ren B, Azzegagh Z, Jaramillo AM, Zhu Y, Pardo-Saganta A, Bagirzadeh R, Flores JR, Han W, Tang YJ, Tu J, Alanis DM, Evans CM, Guindani M, Roche PA, Rajagopal J, Chen J, Davis CW, Tuvim MJ, Dickey BF.

Biosci Rep. 2015 Apr 28;35(3). pii: e00220. doi: 10.1042/BSR20150004.

26.

Baseline Goblet Cell Mucin Secretion in the Airways Exceeds Stimulated Secretion over Extended Time Periods, and Is Sensitive to Shear Stress and Intracellular Mucin Stores.

Zhu Y, Abdullah LH, Doyle SP, Nguyen K, Ribeiro CM, Vasquez PA, Forest MG, Lethem MI, Dickey BF, Davis CW.

PLoS One. 2015 May 29;10(5):e0127267. doi: 10.1371/journal.pone.0127267. eCollection 2015.

27.

The polymeric mucin Muc5ac is required for allergic airway hyperreactivity.

Evans CM, Raclawska DS, Ttofali F, Liptzin DR, Fletcher AA, Harper DN, McGing MA, McElwee MM, Williams OW, Sanchez E, Roy MG, Kindrachuk KN, Wynn TA, Eltzschig HK, Blackburn MR, Tuvim MJ, Janssen WJ, Schwartz DA, Dickey BF.

Nat Commun. 2015 Feb 17;6:6281. doi: 10.1038/ncomms7281.

28.

Non-infectious respiratory disease in non-HIV immunocompromised patients.

Jose RJ, Faiz SA, Dickey BF, Brown JS.

Br J Hosp Med (Lond). 2014 Dec;75(12):691-7. doi: 10.12968/hmed.2014.75.12.691. Review.

PMID:
25488532
29.

Infectious respiratory disease in non-HIV immunocompromised patients.

Jose RJ, Dickey BF, Brown JS.

Br J Hosp Med (Lond). 2014 Dec;75(12):685-90. doi: 10.12968/hmed.2014.75.12.685. Review.

PMID:
25488531
30.

Safety, tolerability, and biomarkers of the treatment of mice with aerosolized Toll-like receptor ligands.

Alfaro VY, Goldblatt DL, Valverde GR, Munsell MF, Quinton LJ, Walker AK, Dantzer R, Varadhachary A, Scott BL, Evans SE, Tuvim MJ, Dickey BF.

Front Pharmacol. 2014 Feb 6;5:8. doi: 10.3389/fphar.2014.00008. eCollection 2014.

31.

Activation of lung toll-like receptors does not exacerbate sickness responses to lipopolysaccharide in mice.

Walker AK, Hsieh J, Luu KV, Radwan AA, Valverde GR, Dickey BF, Tuvim MJ, Dantzer R.

Brain Behav Immun. 2014 May;38:211-9. doi: 10.1016/j.bbi.2014.02.004. Epub 2014 Feb 15.

32.

Promoting effect of neutrophils on lung tumorigenesis is mediated by CXCR2 and neutrophil elastase.

Gong L, Cumpian AM, Caetano MS, Ochoa CE, De la Garza MM, Lapid DJ, Mirabolfathinejad SG, Dickey BF, Zhou Q, Moghaddam SJ.

Mol Cancer. 2013 Dec 9;12(1):154. doi: 10.1186/1476-4598-12-154.

33.

Muc5b is required for airway defence.

Roy MG, Livraghi-Butrico A, Fletcher AA, McElwee MM, Evans SE, Boerner RM, Alexander SN, Bellinghausen LK, Song AS, Petrova YM, Tuvim MJ, Adachi R, Romo I, Bordt AS, Bowden MG, Sisson JH, Woodruff PG, Thornton DJ, Rousseau K, De la Garza MM, Moghaddam SJ, Karmouty-Quintana H, Blackburn MR, Drouin SM, Davis CW, Terrell KA, Grubb BR, O'Neal WK, Flores SC, Cota-Gomez A, Lozupone CA, Donnelly JM, Watson AM, Hennessy CE, Keith RC, Yang IV, Barthel L, Henson PM, Janssen WJ, Schwartz DA, Boucher RC, Dickey BF, Evans CM.

Nature. 2014 Jan 16;505(7483):412-6. doi: 10.1038/nature12807. Epub 2013 Dec 8.

34.

Regulated mucin secretion from airway epithelial cells.

Adler KB, Tuvim MJ, Dickey BF.

Front Endocrinol (Lausanne). 2013 Sep 18;4:129. doi: 10.3389/fendo.2013.00129. Review.

35.

Pneumonia during remission induction chemotherapy in patients with acute leukemia.

Garcia JB, Lei X, Wierda W, Cortes JE, Dickey BF, Evans SE, Ost DE.

Ann Am Thorac Soc. 2013 Oct;10(5):432-40. doi: 10.1513/AnnalsATS.201304-097OC.

36.

Deletion of the gene encoding calcitonin and calcitonin gene-related peptide α does not affect the outcome of severe infection in mice.

Tuvim MJ, Clement CG, Huang ES, Cote GJ, Evans SE, Lei X, Deftos LJ, Gagel RF, Dickey BF.

Am J Respir Cell Mol Biol. 2013 Jul;49(1):151-5. doi: 10.1165/rcmb.2012-0489OC.

37.

Toll-like receptor-2/6 and Toll-like receptor-9 agonists suppress viral replication but not airway hyperreactivity in guinea pigs.

Drake MG, Evans SE, Dickey BF, Fryer AD, Jacoby DB.

Am J Respir Cell Mol Biol. 2013 Jun;48(6):790-6. doi: 10.1165/rcmb.2012-0498OC.

38.

β2-Adrenoceptor agonists are required for development of the asthma phenotype in a murine model.

Thanawala VJ, Forkuo GS, Al-Sawalha N, Azzegagh Z, Nguyen LP, Eriksen JL, Tuvim MJ, Lowder TW, Dickey BF, Knoll BJ, Walker JK, Bond RA.

Am J Respir Cell Mol Biol. 2013 Feb;48(2):220-9. doi: 10.1165/rcmb.2012-0364OC. Epub 2012 Nov 29.

39.

Biochemistry. Walking on solid ground.

Dickey BF.

Science. 2012 Aug 24;337(6097):924-5. doi: 10.1126/science.1227091. No abstract available. Erratum in: Science. 2012 Nov 2;338(6107):604.

40.

Munc18b is an essential gene in mice whose expression is limiting for secretion by airway epithelial and mast cells.

Kim K, Petrova YM, Scott BL, Nigam R, Agrawal A, Evans CM, Azzegagh Z, Gomez A, Rodarte EM, Olkkonen VM, Bagirzadeh R, Piccotti L, Ren B, Yoon JH, McNew JA, Adachi R, Tuvim MJ, Dickey BF.

Biochem J. 2012 Sep 15;446(3):383-94. doi: 10.1042/BJ20120057.

41.

Synergistic TLR2/6 and TLR9 activation protects mice against lethal influenza pneumonia.

Tuvim MJ, Gilbert BE, Dickey BF, Evans SE.

PLoS One. 2012;7(1):e30596. doi: 10.1371/journal.pone.0030596. Epub 2012 Jan 27.

42.

Assessment of intracellular mucin content in vivo.

Piccotti L, Dickey BF, Evans CM.

Methods Mol Biol. 2012;842:279-95. doi: 10.1007/978-1-61779-513-8_17.

43.

Enhancement of lung tumorigenesis in a Gprc5a Knockout mouse by chronic extrinsic airway inflammation.

Barta P, Van Pelt C, Men T, Dickey BF, Lotan R, Moghaddam SJ.

Mol Cancer. 2012 Jan 12;11:4. doi: 10.1186/1476-4598-11-4.

44.

Complementary anti-inflammatory effects of a β-blocker and a corticosteroid in an asthma model.

Nguyen LP, Singh B, Okulate AA, Alfaro VY, Tuvim MJ, Dickey BF, Bond RA.

Naunyn Schmiedebergs Arch Pharmacol. 2012 Feb;385(2):203-10. doi: 10.1007/s00210-011-0692-0. Epub 2011 Oct 2.

PMID:
21964666
45.

A common MUC5B promoter polymorphism and pulmonary fibrosis.

Seibold MA, Wise AL, Speer MC, Steele MP, Brown KK, Loyd JE, Fingerlin TE, Zhang W, Gudmundsson G, Groshong SD, Evans CM, Garantziotis S, Adler KB, Dickey BF, du Bois RM, Yang IV, Herron A, Kervitsky D, Talbert JL, Markin C, Park J, Crews AL, Slifer SH, Auerbach S, Roy MG, Lin J, Hennessy CE, Schwarz MI, Schwartz DA.

N Engl J Med. 2011 Apr 21;364(16):1503-12. doi: 10.1056/NEJMoa1013660.

46.

Muc5ac: a critical component mediating the rejection of enteric nematodes.

Hasnain SZ, Evans CM, Roy M, Gallagher AL, Kindrachuk KN, Barron L, Dickey BF, Wilson MS, Wynn TA, Grencis RK, Thornton DJ.

J Exp Med. 2011 May 9;208(5):893-900. doi: 10.1084/jem.20102057. Epub 2011 Apr 18.

47.

Synergistic interactions of TLR2/6 and TLR9 induce a high level of resistance to lung infection in mice.

Duggan JM, You D, Cleaver JO, Larson DT, Garza RJ, Guzmán Pruneda FA, Tuvim MJ, Zhang J, Dickey BF, Evans SE.

J Immunol. 2011 May 15;186(10):5916-26. doi: 10.4049/jimmunol.1002122. Epub 2011 Apr 11.

48.

Nontypeable Haemophilus influenzae in chronic obstructive pulmonary disease and lung cancer.

Moghaddam SJ, Ochoa CE, Sethi S, Dickey BF.

Int J Chron Obstruct Pulmon Dis. 2011;6:113-23. doi: 10.2147/COPD.S15417. Epub 2011 Jan 27. Review.

49.

Inhaled innate immune ligands to prevent pneumonia.

Evans SE, Tuvim MJ, Fox CJ, Sachdev N, Gibiansky L, Dickey BF.

Br J Pharmacol. 2011 May;163(1):195-206. doi: 10.1111/j.1476-5381.2011.01237.x. Review.

50.

Performance of a standardized bronchoalveolar lavage protocol in a comprehensive cancer center: a prospective 2-year study.

Sampsonas F, Kontoyiannis DP, Dickey BF, Evans SE.

Cancer. 2011 Aug 1;117(15):3424-33. doi: 10.1002/cncr.25905. Epub 2011 Jan 18.

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