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Items: 31


A comparison of interferon gene expression induced by influenza A virus infection of human airway epithelial cells from two different donors.

Ilyushina NA, Dickensheets H, Donnelly RP.

Virus Res. 2019 Apr 15;264:1-7. doi: 10.1016/j.virusres.2019.02.002. Epub 2019 Feb 16.


The Interleukin-13 Receptor-α1 Chain Is Essential for Induction of the Alternative Macrophage Activation Pathway by IL-13 but Not IL-4.

Sheikh F, Dickensheets H, Pedras-Vasconcelos J, Ramalingam T, Helming L, Gordon S, Donnelly RP.

J Innate Immun. 2015;7(5):494-505. doi: 10.1159/000376579. Epub 2015 Mar 7.


An essential role for IFN-β in the induction of IFN-stimulated gene expression by LPS in macrophages.

Sheikh F, Dickensheets H, Gamero AM, Vogel SN, Donnelly RP.

J Leukoc Biol. 2014 Oct;96(4):591-600. doi: 10.1189/jlb.2A0414-191R. Epub 2014 Jul 14.


A variant upstream of IFNL3 (IL28B) creating a new interferon gene IFNL4 is associated with impaired clearance of hepatitis C virus.

Prokunina-Olsson L, Muchmore B, Tang W, Pfeiffer RM, Park H, Dickensheets H, Hergott D, Porter-Gill P, Mumy A, Kohaar I, Chen S, Brand N, Tarway M, Liu L, Sheikh F, Astemborski J, Bonkovsky HL, Edlin BR, Howell CD, Morgan TR, Thomas DL, Rehermann B, Donnelly RP, O'Brien TR.

Nat Genet. 2013 Feb;45(2):164-71. doi: 10.1038/ng.2521. Epub 2013 Jan 6.


Interferon-lambda (IFN-λ) induces signal transduction and gene expression in human hepatocytes, but not in lymphocytes or monocytes.

Dickensheets H, Sheikh F, Park O, Gao B, Donnelly RP.

J Leukoc Biol. 2013 Mar;93(3):377-85. doi: 10.1189/jlb.0812395. Epub 2012 Dec 20.


Interferon-lambda and therapy for chronic hepatitis C virus infection.

Donnelly RP, Dickensheets H, O'Brien TR.

Trends Immunol. 2011 Sep;32(9):443-50. doi: 10.1016/ Epub 2011 Aug 5. Review.


Interleukin-26: an IL-10-related cytokine produced by Th17 cells.

Donnelly RP, Sheikh F, Dickensheets H, Savan R, Young HA, Walter MR.

Cytokine Growth Factor Rev. 2010 Oct;21(5):393-401. doi: 10.1016/j.cytogfr.2010.09.001. Epub 2010 Oct 14. Review.


Tuning sensitivity to IL-4 and IL-13: differential expression of IL-4Ralpha, IL-13Ralpha1, and gammac regulates relative cytokine sensitivity.

Junttila IS, Mizukami K, Dickensheets H, Meier-Schellersheim M, Yamane H, Donnelly RP, Paul WE.

J Exp Med. 2008 Oct 27;205(11):2595-608. doi: 10.1084/jem.20080452. Epub 2008 Oct 13.


Suppressor of cytokine signaling-1 is an IL-4-inducible gene in macrophages and feedback inhibits IL-4 signaling.

Dickensheets H, Vazquez N, Sheikh F, Gingras S, Murray PJ, Ryan JJ, Donnelly RP.

Genes Immun. 2007 Jan;8(1):21-7. Epub 2006 Nov 9.


Alpha and lambda interferon together mediate suppression of CD4 T cells induced by respiratory syncytial virus.

Chi B, Dickensheets HL, Spann KM, Alston MA, Luongo C, Dumoutier L, Huang J, Renauld JC, Kotenko SV, Roederer M, Beeler JA, Donnelly RP, Collins PL, Rabin RL.

J Virol. 2006 May;80(10):5032-40.


Characterization of the mouse IFN-lambda ligand-receptor system: IFN-lambdas exhibit antitumor activity against B16 melanoma.

Lasfar A, Lewis-Antes A, Smirnov SV, Anantha S, Abushahba W, Tian B, Reuhl K, Dickensheets H, Sheikh F, Donnelly RP, Raveche E, Kotenko SV.

Cancer Res. 2006 Apr 15;66(8):4468-77.


Autoantibodies and autoantigens in the urine of SLE patients.

Sciascia SA, Dickensheets H, Picking W, Robson K, Wang D, Ye BH, Zhu L, Stetler DA.

Autoimmunity. 2004 Sep-Nov;37(6-7):503-14.


The expanded family of class II cytokines that share the IL-10 receptor-2 (IL-10R2) chain.

Donnelly RP, Sheikh F, Kotenko SV, Dickensheets H.

J Leukoc Biol. 2004 Aug;76(2):314-21. Epub 2004 May 3. Review.


Human interleukin-19 and its receptor: a potential role in the induction of Th2 responses.

Gallagher G, Eskdale J, Jordan W, Peat J, Campbell J, Boniotto M, Lennon GP, Dickensheets H, Donnelly RP.

Int Immunopharmacol. 2004 May;4(5):615-26. Review.


Cutting edge: IL-26 signals through a novel receptor complex composed of IL-20 receptor 1 and IL-10 receptor 2.

Sheikh F, Baurin VV, Lewis-Antes A, Shah NK, Smirnov SV, Anantha S, Dickensheets H, Dumoutier L, Renauld JC, Zdanov A, Donnelly RP, Kotenko SV.

J Immunol. 2004 Feb 15;172(4):2006-10.


IFN-lambdas mediate antiviral protection through a distinct class II cytokine receptor complex.

Kotenko SV, Gallagher G, Baurin VV, Lewis-Antes A, Shen M, Shah NK, Langer JA, Sheikh F, Dickensheets H, Donnelly RP.

Nat Immunol. 2003 Jan;4(1):69-77. Epub 2002 Dec 16.


Regulation of the dephosphorylation of Stat6. Participation of Tyr-713 in the interleukin-4 receptor alpha, the tyrosine phosphatase SHP-1, and the proteasome.

Hanson EM, Dickensheets H, Qu CK, Donnelly RP, Keegan AD.

J Biol Chem. 2003 Feb 7;278(6):3903-11. Epub 2002 Nov 28.


Identification, cloning, and characterization of a novel soluble receptor that binds IL-22 and neutralizes its activity.

Kotenko SV, Izotova LS, Mirochnitchenko OV, Esterova E, Dickensheets H, Donnelly RP, Pestka S.

J Immunol. 2001 Jun 15;166(12):7096-103.


Cloning, expression and initial characterization of interleukin-19 (IL-19), a novel homologue of human interleukin-10 (IL-10).

Gallagher G, Dickensheets H, Eskdale J, Izotova LS, Mirochnitchenko OV, Peat JD, Vazquez N, Pestka S, Donnelly RP, Kotenko SV.

Genes Immun. 2000 Oct;1(7):442-50.


Interleukin-12 differentially regulates expression of IFN-gamma and interleukin-2 in human T lymphoblasts.

Dickensheets HL, Freeman SL, Donnelly RP.

J Interferon Cytokine Res. 2000 Oct;20(10):897-905.


Differential responses of human monocytes and macrophages to IL-4 and IL-13.

Hart PH, Bonder CS, Balogh J, Dickensheets HL, Donnelly RP, Finlay-Jones JJ.

J Leukoc Biol. 1999 Oct;66(4):575-8. Review.


Interferons inhibit activation of STAT6 by interleukin 4 in human monocytes by inducing SOCS-1 gene expression.

Dickensheets HL, Venkataraman C, Schindler U, Donnelly RP.

Proc Natl Acad Sci U S A. 1999 Sep 14;96(19):10800-5.


The interleukin-10 signal transduction pathway and regulation of gene expression in mononuclear phagocytes.

Donnelly RP, Dickensheets H, Finbloom DS.

J Interferon Cytokine Res. 1999 Jun;19(6):563-73. Review.


Diminished responses to IL-13 by human monocytes differentiated in vitro: role of the IL-13Ralpha1 chain and STAT6.

Hart PH, Bonder CS, Balogh J, Dickensheets HL, Vazquez N, Davies KV, Finlay-Jones JJ, Donnelly RP.

Eur J Immunol. 1999 Jul;29(7):2087-97.


Inhibition of IL-4-inducible gene expression in human monocytes by type I and type II interferons.

Dickensheets HL, Donnelly RP.

J Leukoc Biol. 1999 Mar;65(3):307-12. Review.


Interleukin-10 inhibits expression of both interferon alpha- and interferon gamma- induced genes by suppressing tyrosine phosphorylation of STAT1.

Ito S, Ansari P, Sakatsume M, Dickensheets H, Vazquez N, Donnelly RP, Larner AC, Finbloom DS.

Blood. 1999 Mar 1;93(5):1456-63.


Involvement of the IL-2 receptor gamma-chain (gammac) in the control by IL-4 of human monocyte and macrophage proinflammatory mediator production.

Bonder CS, Dickensheets HL, Finlay-Jones JJ, Donnelly RP, Hart PH.

J Immunol. 1998 Apr 15;160(8):4048-56.


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