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Items: 1 to 50 of 157

1.

Activity of mefloquine and mefloquine derivatives against Echinococcus multilocularis.

Rufener R, Ritler D, Zielinski J, Dick L, da Silva ET, da Silva Araujo A, Joekel DE, Czock D, Goepfert C, Moraes AM, de Souza MVN, Müller J, Mevissen M, Hemphill A, Lundström-Stadelmann B.

Int J Parasitol Drugs Drug Resist. 2018 Aug;8(2):331-340. doi: 10.1016/j.ijpddr.2018.06.004. Epub 2018 Jun 15.

2.

Direct Li+ incorporation during the anodic formation of compact TiO2 layers.

Peñafiel-Castro JA, Hahn B, Maltez RL, Knörnschild G, Allongue P, Dick LFP.

Chem Commun (Camb). 2018 Mar 27;54(26):3251-3254. doi: 10.1039/c8cc00829a.

PMID:
29537052
3.

A small-molecule inhibitor of the ubiquitin activating enzyme for cancer treatment.

Hyer ML, Milhollen MA, Ciavarri J, Fleming P, Traore T, Sappal D, Huck J, Shi J, Gavin J, Brownell J, Yang Y, Stringer B, Griffin R, Bruzzese F, Soucy T, Duffy J, Rabino C, Riceberg J, Hoar K, Lublinsky A, Menon S, Sintchak M, Bump N, Pulukuri SM, Langston S, Tirrell S, Kuranda M, Veiby P, Newcomb J, Li P, Wu JT, Powe J, Dick LR, Greenspan P, Galvin K, Manfredi M, Claiborne C, Amidon BS, Bence NF.

Nat Med. 2018 Feb;24(2):186-193. doi: 10.1038/nm.4474. Epub 2018 Jan 15.

PMID:
29334375
4.

Benefit of social media on patient engagement and satisfaction: Results of a 9-month, qualitative pilot study using Facebook.

Dhar VK, Kim Y, Graff JT, Jung AD, Garrett J, Dick LE, Harris J, Shah SA.

Surgery. 2018 Mar;163(3):565-570. doi: 10.1016/j.surg.2017.09.056. Epub 2017 Nov 29.

PMID:
29195735
5.

Probing the roles of SUMOylation in cancer cell biology by using a selective SAE inhibitor.

He X, Riceberg J, Soucy T, Koenig E, Minissale J, Gallery M, Bernard H, Yang X, Liao H, Rabino C, Shah P, Xega K, Yan ZH, Sintchak M, Bradley J, Xu H, Duffey M, England D, Mizutani H, Hu Z, Guo J, Chau R, Dick LR, Brownell JE, Newcomb J, Langston S, Lightcap ES, Bence N, Pulukuri SM.

Nat Chem Biol. 2017 Nov;13(11):1164-1171. doi: 10.1038/nchembio.2463. Epub 2017 Sep 11.

PMID:
28892090
6.

First to help, but last in line.

Dick L.

Nurs Stand. 2017 Jul 5;31(45):32. doi: 10.7748/ns.31.45.32.s28.

PMID:
28677440
7.

Re: Bacteriological study in perianal abscess is not useful and not cost-effective.

Bisset CN, Dick L, Chin YR, Summers L, Renwick A.

ANZ J Surg. 2017 May;87(5):420-421. doi: 10.1111/ans.13878. No abstract available.

PMID:
28470701
8.

Enterobius vermicularis presentation during laparoscopic cholecystectomy.

Dick L, Hannay J.

J Surg Case Rep. 2017 Jan 17;2017(1). pii: rjw239. doi: 10.1093/jscr/rjw239.

9.

Reduced nicotine content cigarettes and use of alternative nicotine products: exploratory trial.

Hatsukami DK, Luo X, Dick L, Kangkum M, Allen SS, Murphy SE, Hecht SS, Shields PG, al'Absi M.

Addiction. 2017 Jan;112(1):156-167. doi: 10.1111/add.13603. Epub 2016 Nov 2.

10.

Risk Management for Materials and Components Used in Orally Inhaled and Nasal Drug Products.

Stults CL, Reckzuegel G, Bailey A, Petersen J, Dick L, Feinberg T, Feilden A, Miller S, Connors J, Nagao LM.

Pharm Res. 2016 Jan;33(1):1-17. doi: 10.1007/s11095-015-1770-7. Epub 2015 Sep 3. Review. No abstract available.

PMID:
26334501
11.

Label-free quantitative mass spectrometry for analysis of protein antigens in a meningococcal group B outer membrane vesicle vaccine.

Dick LW Jr, Mehl JT, Loughney JW, Mach A, Rustandi RR, Ha S, Zhang L, Przysiecki CT, Dieter L, Hoang VM.

Hum Vaccin Immunother. 2015;11(6):1518-25. doi: 10.1080/21645515.2015.1016678.

12.

Soluble Human Cytomegalovirus gH/gL/pUL128-131 Pentameric Complex, but Not gH/gL, Inhibits Viral Entry to Epithelial Cells and Presents Dominant Native Neutralizing Epitopes.

Loughney JW, Rustandi RR, Wang D, Troutman MC, Dick LW Jr, Li G, Liu Z, Li F, Freed DC, Price CE, Hoang VM, Culp TD, DePhillips PA, Fu TM, Ha S.

J Biol Chem. 2015 Jun 26;290(26):15985-95. doi: 10.1074/jbc.M115.652230. Epub 2015 May 6.

13.

Characterization of the loss of SUMO pathway function on cancer cells and tumor proliferation.

He X, Riceberg J, Pulukuri SM, Grossman S, Shinde V, Shah P, Brownell JE, Dick L, Newcomb J, Bence N.

PLoS One. 2015 Apr 10;10(4):e0123882. doi: 10.1371/journal.pone.0123882. eCollection 2015.

14.

Cleavage Specificity of Mycobacterium tuberculosis ClpP1P2 Protease and Identification of Novel Peptide Substrates and Boronate Inhibitors with Anti-bacterial Activity.

Akopian T, Kandror O, Tsu C, Lai JH, Wu W, Liu Y, Zhao P, Park A, Wolf L, Dick LR, Rubin EJ, Bachovchin W, Goldberg AL.

J Biol Chem. 2015 Apr 24;290(17):11008-20. doi: 10.1074/jbc.M114.625640. Epub 2015 Mar 10.

15.

Deficiency in lymphotoxin β receptor protects from atherosclerosis in apoE-deficient mice.

Grandoch M, Feldmann K, Göthert JR, Dick LS, Homann S, Klatt C, Bayer JK, Waldheim JN, Rabausch B, Nagy N, Oberhuber A, Deenen R, Köhrer K, Lehr S, Homey B, Pfeffer K, Fischer JW.

Circ Res. 2015 Apr 10;116(8):e57-68. doi: 10.1161/CIRCRESAHA.116.305723. Epub 2015 Mar 4.

16.

Identification of potent and selective non-covalent inhibitors of the Plasmodium falciparum proteasome.

Li H, Tsu C, Blackburn C, Li G, Hales P, Dick L, Bogyo M.

J Am Chem Soc. 2014 Oct 1;136(39):13562-5. doi: 10.1021/ja507692y. Epub 2014 Sep 19.

17.

Mechanistic study of Uba5 enzyme and the Ufm1 conjugation pathway.

Gavin JM, Hoar K, Xu Q, Ma J, Lin Y, Chen J, Chen W, Bruzzese FJ, Harrison S, Mallender WD, Bump NJ, Sintchak MD, Bence NF, Li P, Dick LR, Gould AE, Chen JJ.

J Biol Chem. 2014 Aug 15;289(33):22648-58. doi: 10.1074/jbc.M114.573972. Epub 2014 Jun 25.

18.

Autoubiquitination of the 26S proteasome on Rpn13 regulates breakdown of ubiquitin conjugates.

Besche HC, Sha Z, Kukushkin NV, Peth A, Hock EM, Kim W, Gygi S, Gutierrez JA, Liao H, Dick L, Goldberg AL.

EMBO J. 2014 May 16;33(10):1159-76. doi: 10.1002/embj.201386906. Epub 2014 May 8.

19.

"On the scene": Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.

Hoying C, Lecher WT, Mosko DD, Roberto N, Mason C, Murphy SW, Taylor J, Cortina S, Mathison E, Dick L, Schoettker PJ, Britto MT.

Nurs Adm Q. 2014 Jan-Mar;38(1):27-54. doi: 10.1097/NAQ.0000000000000002.

PMID:
24317030
20.

Elimination of the antimicrobial action of the organoarsenical cancer therapeutic, 4-(N-(S-glutathionylacetyl)amino) phenylarsonous acid, before finished product sterility testing.

Dick LJ, Gray A, Ram A, Hume A, Parris C, Hogg PJ, Elliott MA, Ford SJ, Halbert GW.

J Pharm Pharmacol. 2013 Nov;65(11):1664-9. doi: 10.1111/jphp.12143. Epub 2013 Sep 18.

PMID:
24102542
21.

N,C-Capped dipeptides with selectivity for mycobacterial proteasome over human proteasomes: role of S3 and S1 binding pockets.

Lin G, Chidawanyika T, Tsu C, Warrier T, Vaubourgeix J, Blackburn C, Gigstad K, Sintchak M, Dick L, Nathan C.

J Am Chem Soc. 2013 Jul 10;135(27):9968-71. doi: 10.1021/ja400021x. Epub 2013 Jun 25.

22.

Absolute quantification of E1, ubiquitin-like proteins and Nedd8-MLN4924 adduct by mass spectrometry.

Yang X, Brownell JE, Xu Q, Zhu F, Ma J, Loke HK, Rollins N, Soucy TA, Minissale JJ, Thomas MP, Mallender WD, Dick LR, Li P, Liao H.

Cell Biochem Biophys. 2013 Sep;67(1):139-47. doi: 10.1007/s12013-013-9625-5.

PMID:
23754621
23.

Evaluating the occurrence of host-specific , general fecal indicators, and bacterial pathogens in a mixed-use watershed.

Drozd M, Merrick NN, Sanad YM, Dick LK, Dick WA, Rajashekara G.

J Environ Qual. 2013 May-Jun;42(3):713-25. doi: 10.2134/jeq2012.0359.

PMID:
23673938
24.

Quantifiable analysis of cellular pathway inhibition of a Nedd8-activating enzyme inhibitor, MLN4924, using AlphaScreen.

Yan ZH, Burkhardt A, Loke HK, Chen J, Xu Q, Brauer P, Ma J, Lin Y, Garcia K, Dick LR, Bembenek ME.

Anal Biochem. 2013 Aug 15;439(2):109-15. doi: 10.1016/j.ab.2013.04.016. Epub 2013 Apr 25.

PMID:
23624319
25.

Improved pharmaceutical stability of a boronphenylalanine mannitol formulation for boron neutron capture therapy.

Halbert G, Elliott M, Ford S, Dick L, Schmidt E.

Eur J Pharm Sci. 2013 Mar 12;48(4-5):735-9. doi: 10.1016/j.ejps.2013.01.008. Epub 2013 Jan 23.

PMID:
23354152
26.

Sulfidated TiO2 nanotubes: a potential 3D cathode material for Li-ion micro batteries.

Kyeremateng NA, Plylahan N, dos Santos AC, Taveira LV, Dick LF, Djenizian T.

Chem Commun (Camb). 2013 May 14;49(39):4205-7. doi: 10.1039/c2cc36857a. Epub 2012 Nov 20.

PMID:
23165523
27.

Treatment-emergent mutations in NAEβ confer resistance to the NEDD8-activating enzyme inhibitor MLN4924.

Milhollen MA, Thomas MP, Narayanan U, Traore T, Riceberg J, Amidon BS, Bence NF, Bolen JB, Brownell J, Dick LR, Loke HK, McDonald AA, Ma J, Manfredi MG, Sells TB, Sintchak MD, Yang X, Xu Q, Koenig EM, Gavin JM, Smith PG.

Cancer Cell. 2012 Mar 20;21(3):388-401. doi: 10.1016/j.ccr.2012.02.009.

28.

Mechanistic studies on activation of ubiquitin and di-ubiquitin-like protein, FAT10, by ubiquitin-like modifier activating enzyme 6, Uba6.

Gavin JM, Chen JJ, Liao H, Rollins N, Yang X, Xu Q, Ma J, Loke HK, Lingaraj T, Brownell JE, Mallender WD, Gould AE, Amidon BS, Dick LR.

J Biol Chem. 2012 May 4;287(19):15512-22. doi: 10.1074/jbc.M111.336198. Epub 2012 Mar 15.

29.

Pharmaceutical development of the novel arsenical based cancer therapeutic GSAO for Phase I clinical trial.

Elliott MA, Ford SJ, Prasad E, Dick LJ, Farmer H, Hogg PJ, Halbert GW.

Int J Pharm. 2012 Apr 15;426(1-2):67-75. doi: 10.1016/j.ijpharm.2012.01.024. Epub 2012 Jan 21.

PMID:
22286018
30.

Genetic markers for rapid PCR-based identification of gull, Canada goose, duck, and chicken fecal contamination in water.

Green HC, Dick LK, Gilpin B, Samadpour M, Field KG.

Appl Environ Microbiol. 2012 Jan;78(2):503-10. doi: 10.1128/AEM.05734-11. Epub 2011 Nov 11.

31.

Changes in the ratio of free NEDD8 to ubiquitin triggers NEDDylation by ubiquitin enzymes.

Hjerpe R, Thomas Y, Chen J, Zemla A, Curran S, Shpiro N, Dick LR, Kurz T.

Biochem J. 2012 Feb 1;441(3):927-36. doi: 10.1042/BJ20111671.

32.

Mechanistic studies of substrate-assisted inhibition of ubiquitin-activating enzyme by adenosine sulfamate analogues.

Chen JJ, Tsu CA, Gavin JM, Milhollen MA, Bruzzese FJ, Mallender WD, Sintchak MD, Bump NJ, Yang X, Ma J, Loke HK, Xu Q, Li P, Bence NF, Brownell JE, Dick LR.

J Biol Chem. 2011 Nov 25;286(47):40867-77. doi: 10.1074/jbc.M111.279984. Epub 2011 Oct 3.

33.

The NEDD8 Conjugation Pathway and Its Relevance in Cancer Biology and Therapy.

Soucy TA, Dick LR, Smith PG, Milhollen MA, Brownell JE.

Genes Cancer. 2010 Jul;1(7):708-16. doi: 10.1177/1947601910382898.

34.

Boron phenylalanine and related impurities: HPLC analysis, stability profile and degradation pathways.

Dick L, Dooley N, Elliott MA, Ford SJ, Gordon MR, Halbert GW, Kerr WJ.

J Pharm Biomed Anal. 2011 Nov 1;56(3):633-6. doi: 10.1016/j.jpba.2011.06.025. Epub 2011 Jul 1.

PMID:
21775086
35.

Preclinical evaluation of the antitumor activity of bortezomib in combination with vitamin C or with epigallocatechin gallate, a component of green tea.

Bannerman B, Xu L, Jones M, Tsu C, Yu J, Hales P, Monbaliu J, Fleming P, Dick L, Manfredi M, Claiborne C, Bolen J, Kupperman E, Berger A.

Cancer Chemother Pharmacol. 2011 Nov;68(5):1145-54. doi: 10.1007/s00280-011-1591-2. Epub 2011 Mar 13.

36.

Demonstrating β-glucan and yeast peptide clearance in biopharmaceutical downstream processes.

Jiang C, Scherfner S, Dick LW Jr, Mahon D, Qiu D, Cheng KC, Shukla AA.

Biotechnol Prog. 2011 Mar-Apr;27(2):442-50. doi: 10.1002/btpr.568. Epub 2011 Mar 1. Erratum in: Biotechnol Prog. 2011 Jul-Aug;27(4):1195. Dick, Lawrence W Jr [added]; Mahon, David [added]; Qiu, Difei [added]; Cheng, Kuang-Chuan [added].

PMID:
21365784
37.

Integrative analysis of the Caenorhabditis elegans genome by the modENCODE project.

Gerstein MB, Lu ZJ, Van Nostrand EL, Cheng C, Arshinoff BI, Liu T, Yip KY, Robilotto R, Rechtsteiner A, Ikegami K, Alves P, Chateigner A, Perry M, Morris M, Auerbach RK, Feng X, Leng J, Vielle A, Niu W, Rhrissorrakrai K, Agarwal A, Alexander RP, Barber G, Brdlik CM, Brennan J, Brouillet JJ, Carr A, Cheung MS, Clawson H, Contrino S, Dannenberg LO, Dernburg AF, Desai A, Dick L, Dosé AC, Du J, Egelhofer T, Ercan S, Euskirchen G, Ewing B, Feingold EA, Gassmann R, Good PJ, Green P, Gullier F, Gutwein M, Guyer MS, Habegger L, Han T, Henikoff JG, Henz SR, Hinrichs A, Holster H, Hyman T, Iniguez AL, Janette J, Jensen M, Kato M, Kent WJ, Kephart E, Khivansara V, Khurana E, Kim JK, Kolasinska-Zwierz P, Lai EC, Latorre I, Leahey A, Lewis S, Lloyd P, Lochovsky L, Lowdon RF, Lubling Y, Lyne R, MacCoss M, Mackowiak SD, Mangone M, McKay S, Mecenas D, Merrihew G, Miller DM 3rd, Muroyama A, Murray JI, Ooi SL, Pham H, Phippen T, Preston EA, Rajewsky N, Rätsch G, Rosenbaum H, Rozowsky J, Rutherford K, Ruzanov P, Sarov M, Sasidharan R, Sboner A, Scheid P, Segal E, Shin H, Shou C, Slack FJ, Slightam C, Smith R, Spencer WC, Stinson EO, Taing S, Takasaki T, Vafeados D, Voronina K, Wang G, Washington NL, Whittle CM, Wu B, Yan KK, Zeller G, Zha Z, Zhong M, Zhou X; modENCODE Consortium, Ahringer J, Strome S, Gunsalus KC, Micklem G, Liu XS, Reinke V, Kim SK, Hillier LW, Henikoff S, Piano F, Snyder M, Stein L, Lieb JD, Waterston RH.

Science. 2010 Dec 24;330(6012):1775-87. doi: 10.1126/science.1196914. Epub 2010 Dec 22. Erratum in: Science. 2011 Jan 7;331(6013):30.

38.

Serum cardiac troponin I concentrations transiently increase in rats given rosiglitazone.

Mikaelian I, Buness A, Hirkaler G, Fernandes R, Coluccio D, Geng W, Visalli T, Bachynsky MO, Berkofsky-Fessler W, Kanwal C, Hilton H, Nicklaus R, Hoflack JC, Dunn M, Sanders M, Giron M, Boyle BW, Singer T, Dick LS.

Toxicol Lett. 2011 Mar 5;201(2):110-5. doi: 10.1016/j.toxlet.2010.12.012. Epub 2010 Dec 21.

PMID:
21172411
39.

Ubiquitin-like protein conjugation and the ubiquitin-proteasome system as drug targets.

Bedford L, Lowe J, Dick LR, Mayer RJ, Brownell JE.

Nat Rev Drug Discov. 2011 Jan;10(1):29-46. doi: 10.1038/nrd3321. Epub 2010 Dec 10. Review.

PMID:
21151032
40.

Optimization of a series of dipeptides with a P3 threonine residue as non-covalent inhibitors of the chymotrypsin-like activity of the human 20S proteasome.

Blackburn C, Barrett C, Blank JL, Bruzzese FJ, Bump N, Dick LR, Fleming P, Garcia K, Hales P, Hu Z, Jones M, Liu JX, Sappal DS, Sintchak MD, Tsu C, Gigstad KM.

Bioorg Med Chem Lett. 2010 Nov 15;20(22):6581-6. doi: 10.1016/j.bmcl.2010.09.032. Epub 2010 Sep 15.

PMID:
20875739
41.

Characterization of a new series of non-covalent proteasome inhibitors with exquisite potency and selectivity for the 20S beta5-subunit.

Blackburn C, Gigstad KM, Hales P, Garcia K, Jones M, Bruzzese FJ, Barrett C, Liu JX, Soucy TA, Sappal DS, Bump N, Olhava EJ, Fleming P, Dick LR, Tsu C, Sintchak MD, Blank JL.

Biochem J. 2010 Sep 15;430(3):461-76. doi: 10.1042/BJ20100383. Erratum in: Biochem J. 2010 Oct 11;431(3):433.

42.

A simple reversed phase high-performance liquid chromatography method for polysorbate 80 quantitation in monoclonal antibody drug products.

Adamo M, Dick LW Jr, Qiu D, Lee AH, Devincentis J, Cheng KC.

J Chromatogr B Analyt Technol Biomed Life Sci. 2010 Jul 1;878(21):1865-70. doi: 10.1016/j.jchromb.2010.04.039. Epub 2010 May 4.

PMID:
20537600
43.

MLN4924, a NEDD8-activating enzyme inhibitor, is active in diffuse large B-cell lymphoma models: rationale for treatment of NF-{kappa}B-dependent lymphoma.

Milhollen MA, Traore T, Adams-Duffy J, Thomas MP, Berger AJ, Dang L, Dick LR, Garnsey JJ, Koenig E, Langston SP, Manfredi M, Narayanan U, Rolfe M, Staudt LM, Soucy TA, Yu J, Zhang J, Bolen JB, Smith PG.

Blood. 2010 Sep 2;116(9):1515-23. doi: 10.1182/blood-2010-03-272567. Epub 2010 Jun 4.

44.

Improving observation status in a hospital.

Fleischner N, Gershwin RJ, Dick L.

Physician Exec. 2010 Mar-Apr;36(2):34-7. No abstract available.

PMID:
20411844
45.

Novel inorganic host layered double hydroxides intercalated with guest organic inhibitors for anticorrosion applications.

Poznyak SK, Tedim J, Rodrigues LM, Salak AN, Zheludkevich ML, Dick LF, Ferreira MG.

ACS Appl Mater Interfaces. 2009 Oct;1(10):2353-62. doi: 10.1021/am900495r.

PMID:
20355873
46.

Relative decay of Bacteroidales microbial source tracking markers and cultivated Escherichia coli in freshwater microcosms.

Dick LK, Stelzer EA, Bertke EE, Fong DL, Stoeckel DM.

Appl Environ Microbiol. 2010 May;76(10):3255-62. doi: 10.1128/AEM.02636-09. Epub 2010 Mar 26.

47.

Evaluation of the proteasome inhibitor MLN9708 in preclinical models of human cancer.

Kupperman E, Lee EC, Cao Y, Bannerman B, Fitzgerald M, Berger A, Yu J, Yang Y, Hales P, Bruzzese F, Liu J, Blank J, Garcia K, Tsu C, Dick L, Fleming P, Yu L, Manfredi M, Rolfe M, Bolen J.

Cancer Res. 2010 Mar 1;70(5):1970-80. doi: 10.1158/0008-5472.CAN-09-2766. Epub 2010 Feb 16. Erratum in: Cancer Res. 2010 May 1;70(9):3853. Hales, Paul [added].

48.

Substrate-assisted inhibition of ubiquitin-like protein-activating enzymes: the NEDD8 E1 inhibitor MLN4924 forms a NEDD8-AMP mimetic in situ.

Brownell JE, Sintchak MD, Gavin JM, Liao H, Bruzzese FJ, Bump NJ, Soucy TA, Milhollen MA, Yang X, Burkhardt AL, Ma J, Loke HK, Lingaraj T, Wu D, Hamman KB, Spelman JJ, Cullis CA, Langston SP, Vyskocil S, Sells TB, Mallender WD, Visiers I, Li P, Claiborne CF, Rolfe M, Bolen JB, Dick LR.

Mol Cell. 2010 Jan 15;37(1):102-11. doi: 10.1016/j.molcel.2009.12.024.

49.

Building on bortezomib: second-generation proteasome inhibitors as anti-cancer therapy.

Dick LR, Fleming PE.

Drug Discov Today. 2010 Mar;15(5-6):243-9. doi: 10.1016/j.drudis.2010.01.008. Epub 2010 Jan 29. Review.

PMID:
20116451
50.

The C. elegans dosage compensation complex propagates dynamically and independently of X chromosome sequence.

Ercan S, Dick LL, Lieb JD.

Curr Biol. 2009 Nov 17;19(21):1777-87. doi: 10.1016/j.cub.2009.09.047. Epub 2009 Oct 22.

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