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Items: 1 to 50 of 58


Cerebrovascular miRNAs correlate with the clearance of Aβ through perivascular route in younger 3xTg-AD mice.

Fu L, Jiang G, Weng H, Dick GM, Chang Y, Kassab GS.

Brain Pathol. 2020 Jan;30(1):92-105. doi: 10.1111/bpa.12759. Epub 2019 Jul 4.


Local metabolic hypothesis is not sufficient to explain coronary autoregulatory behavior.

Kiel AM, Goodwill AG, Baker HE, Dick GM, Tune JD.

Basic Res Cardiol. 2018 Aug 2;113(5):33. doi: 10.1007/s00395-018-0691-0.


Role of Coronary Myogenic Response in Pressure-Flow Autoregulation in Swine: A Meta-Analysis With Coronary Flow Modeling.

Dick GM, Namani R, Patel B, Kassab GS.

Front Physiol. 2018 May 23;9:580. doi: 10.3389/fphys.2018.00580. eCollection 2018.


Dynamic Regulation of the Subunit Composition of BK Channels in Smooth Muscle.

Dick GM, Tune JD.

Circ Res. 2017 Sep 1;121(6):594-595. doi: 10.1161/CIRCRESAHA.117.311723. No abstract available.


Regulation of Coronary Blood Flow.

Goodwill AG, Dick GM, Kiel AM, Tune JD.

Compr Physiol. 2017 Mar 16;7(2):321-382. doi: 10.1002/cphy.c160016. Review.


Critical contribution of KV1 channels to the regulation of coronary blood flow.

Goodwill AG, Noblet JN, Sassoon D, Fu L, Kassab GS, Schepers L, Herring BP, Rottgen TS, Tune JD, Dick GM.

Basic Res Cardiol. 2016 Sep;111(5):56. doi: 10.1007/s00395-016-0575-0. Epub 2016 Aug 5.


Differential regulation of TRPV1 channels by H2O2: implications for diabetic microvascular dysfunction.

DelloStritto DJ, Connell PJ, Dick GM, Fancher IS, Klarich B, Fahmy JN, Kang PT, Chen YR, Damron DS, Thodeti CK, Bratz IN.

Basic Res Cardiol. 2016 Mar;111(2):21. doi: 10.1007/s00395-016-0539-4. Epub 2016 Feb 24.


KV7 channels contribute to paracrine, but not metabolic or ischemic, regulation of coronary vascular reactivity in swine.

Goodwill AG, Fu L, Noblet JN, Casalini ED, Sassoon D, Berwick ZC, Kassab GS, Tune JD, Dick GM.

Am J Physiol Heart Circ Physiol. 2016 Mar 15;310(6):H693-704. doi: 10.1152/ajpheart.00688.2015. Epub 2016 Jan 29.


Early detection of cardiac dysfunction in the type 1 diabetic heart using speckle-tracking based strain imaging.

Shepherd DL, Nichols CE, Croston TL, McLaughlin SL, Petrone AB, Lewis SE, Thapa D, Long DM, Dick GM, Hollander JM.

J Mol Cell Cardiol. 2016 Jan;90:74-83. doi: 10.1016/j.yjmcc.2015.12.001. Epub 2015 Dec 3.


Diphenyl phosphine oxide-1-sensitive K(+) channels contribute to the vascular tone and reactivity of resistance arteries from brain and skeletal muscle.

Fancher IS, Butcher JT, Brooks SD, Rottgen TS, Skaff PR, Frisbee JC, Dick GM.

Microcirculation. 2015 May;22(4):315-25. doi: 10.1111/micc.12201.


Chronic and selective inhibition of basolateral membrane Na-K-ATPase uniquely regulates brush border membrane Na absorption in intestinal epithelial cells.

Manoharan P, Gayam S, Arthur S, Palaniappan B, Singh S, Dick GM, Sundaram U.

Am J Physiol Cell Physiol. 2015 Apr 15;308(8):C650-6. doi: 10.1152/ajpcell.00355.2014. Epub 2015 Feb 4.


Bisphenol A activates BK channels through effects on α and β1 subunits.

Rottgen TS, Fancher IS, Asano S, Widlanski TS, Dick GM.

Channels (Austin). 2014;8(3):249-57.


Contribution of electromechanical coupling between Kv and Ca v1.2 channels to coronary dysfunction in obesity.

Berwick ZC, Dick GM, O'Leary HA, Bender SB, Goodwill AG, Moberly SP, Owen MK, Miller SJ, Obukhov AG, Tune JD.

Basic Res Cardiol. 2013 Sep;108(5):370. doi: 10.1007/s00395-013-0370-0. Epub 2013 Jul 16.


Interactions between A(2A) adenosine receptors, hydrogen peroxide, and KATP channels in coronary reactive hyperemia.

Sharifi-Sanjani M, Zhou X, Asano S, Tilley S, Ledent C, Teng B, Dick GM, Mustafa SJ.

Am J Physiol Heart Circ Physiol. 2013 May 15;304(10):H1294-301. doi: 10.1152/ajpheart.00637.2012. Epub 2013 Mar 22.


Adenosine A1 receptors link to smooth muscle contraction via CYP4a, protein kinase C-α, and ERK1/2.

Kunduri SS, Mustafa SJ, Ponnoth DS, Dick GM, Nayeem MA.

J Cardiovasc Pharmacol. 2013 Jul;62(1):78-83. doi: 10.1097/FJC.0b013e3182919591.


Diabetes mellitus reduces the function and expression of ATP-dependent K⁺ channels in cardiac mitochondria.

Fancher IS, Dick GM, Hollander JM.

Life Sci. 2013 Mar 28;92(11):664-8. doi: 10.1016/j.lfs.2012.11.019. Epub 2012 Dec 19.


Penitrem A as a tool for understanding the role of large conductance Ca(2+)/voltage-sensitive K(+) channels in vascular function.

Asano S, Bratz IN, Berwick ZC, Fancher IS, Tune JD, Dick GM.

J Pharmacol Exp Ther. 2012 Aug;342(2):453-60. doi: 10.1124/jpet.111.191072. Epub 2012 May 11.


Contribution of voltage-dependent K+ and Ca2+ channels to coronary pressure-flow autoregulation.

Berwick ZC, Moberly SP, Kohr MC, Morrical EB, Kurian MM, Dick GM, Tune JD.

Basic Res Cardiol. 2012 May;107(3):264. doi: 10.1007/s00395-012-0264-6. Epub 2012 Mar 31.


Contribution of voltage-dependent K⁺ channels to metabolic control of coronary blood flow.

Berwick ZC, Dick GM, Moberly SP, Kohr MC, Sturek M, Tune JD.

J Mol Cell Cardiol. 2012 Apr;52(4):912-9. doi: 10.1016/j.yjmcc.2011.07.004. Epub 2011 Jul 12.


Heart of the matter: coronary dysfunction in metabolic syndrome.

Berwick ZC, Dick GM, Tune JD.

J Mol Cell Cardiol. 2012 Apr;52(4):848-56. doi: 10.1016/j.yjmcc.2011.06.025. Epub 2011 Jul 13. Review.


Contribution of adenosine A(2A) and A(2B) receptors to ischemic coronary dilation: role of K(V) and K(ATP) channels.

Berwick ZC, Payne GA, Lynch B, Dick GM, Sturek M, Tune JD.

Microcirculation. 2010 Nov;17(8):600-7. doi: 10.1111/j.1549-8719.2010.00054.x.


Role of potassium channels in coronary vasodilation.

Dick GM, Tune JD.

Exp Biol Med (Maywood). 2010 Jan;235(1):10-22. doi: 10.1258/ebm.2009.009201. Review.


Bisphenol A activates Maxi-K (K(Ca)1.1) channels in coronary smooth muscle.

Asano S, Tune JD, Dick GM.

Br J Pharmacol. 2010 May;160(1):160-70. doi: 10.1111/j.1476-5381.2010.00687.x. Epub 2010 Mar 19.


Metabolic syndrome reduces the contribution of K+ channels to ischemic coronary vasodilation.

Borbouse L, Dick GM, Payne GA, Berwick ZC, Neeb ZP, Alloosh M, Bratz IN, Sturek M, Tune JD.

Am J Physiol Heart Circ Physiol. 2010 Apr;298(4):H1182-9. doi: 10.1152/ajpheart.00888.2009. Epub 2010 Jan 29.


Contribution of BK(Ca) channels to local metabolic coronary vasodilation: Effects of metabolic syndrome.

Borbouse L, Dick GM, Payne GA, Payne BD, Svendsen MC, Neeb ZP, Alloosh M, Bratz IN, Sturek M, Tune JD.

Am J Physiol Heart Circ Physiol. 2010 Mar;298(3):H966-73. doi: 10.1152/ajpheart.00876.2009. Epub 2009 Dec 31.


Impaired function of coronary BK(Ca) channels in metabolic syndrome.

Borbouse L, Dick GM, Asano S, Bender SB, Dincer UD, Payne GA, Neeb ZP, Bratz IN, Sturek M, Tune JD.

Am J Physiol Heart Circ Physiol. 2009 Nov;297(5):H1629-37. doi: 10.1152/ajpheart.00466.2009. Epub 2009 Sep 11.


Aging and muscle fiber type alter K+ channel contributions to the myogenic response in skeletal muscle arterioles.

Kang LS, Kim S, Dominguez JM 2nd, Sindler AL, Dick GM, Muller-Delp JM.

J Appl Physiol (1985). 2009 Aug;107(2):389-98. doi: 10.1152/japplphysiol.91245.2008. Epub 2009 Apr 30.


Endogenous adipose-derived factors diminish coronary endothelial function via inhibition of nitric oxide synthase.

Payne GA, Borbouse L, Bratz IN, Roell WC, Bohlen HG, Dick GM, Tune JD.

Microcirculation. 2008 Jul;15(5):417-26. doi: 10.1080/10739680701858447.


Impaired capsaicin-induced relaxation of coronary arteries in a porcine model of the metabolic syndrome.

Bratz IN, Dick GM, Tune JD, Edwards JM, Neeb ZP, Dincer UD, Sturek M.

Am J Physiol Heart Circ Physiol. 2008 Jun;294(6):H2489-96. doi: 10.1152/ajpheart.01191.2007. Epub 2008 Apr 4.


Voltage-dependent K+ channels regulate the duration of reactive hyperemia in the canine coronary circulation.

Dick GM, Bratz IN, Borbouse L, Payne GA, Dincer UD, Knudson JD, Rogers PA, Tune JD.

Am J Physiol Heart Circ Physiol. 2008 May;294(5):H2371-81. doi: 10.1152/ajpheart.01279.2007. Epub 2008 Mar 28.


Adenosine A1 receptors in neointimal hyperplasia and in-stent stenosis in Ossabaw miniature swine.

Edwards JM, Alloosh MA, Long XL, Dick GM, Lloyd PG, Mokelke EA, Sturek M.

Coron Artery Dis. 2008 Feb;19(1):27-31. doi: 10.1097/MCA.0b013e3282f262b4.


Redox-dependent coronary metabolic dilation.

Saitoh S, Kiyooka T, Rocic P, Rogers PA, Zhang C, Swafford A, Dick GM, Viswanathan C, Park Y, Chilian WM.

Am J Physiol Heart Circ Physiol. 2007 Dec;293(6):H3720-5. Epub 2007 Oct 26.


Mechanisms of coronary dysfunction in obesity and insulin resistance.

Knudson JD, Dincer UD, Bratz IN, Sturek M, Dick GM, Tune JD.

Microcirculation. 2007 Jun-Jul;14(4-5):317-38. Review.


Adipokines and coronary vasomotor dysfunction.

Knudson JD, Dick GM, Tune JD.

Exp Biol Med (Maywood). 2007 Jun;232(6):727-36. Review.


Knockout mice reveal that the angiotensin II type 1B receptor links to smooth muscle contraction.

Swafford AN Jr, Harrison-Bernard LM, Dick GM.

Am J Hypertens. 2007 Mar;20(3):335-7.


Restoration of coronary endothelial function in obese Zucker rats by a low-carbohydrate diet.

Focardi M, Dick GM, Picchi A, Zhang C, Chilian WM.

Am J Physiol Heart Circ Physiol. 2007 May;292(5):H2093-9. Epub 2007 Jan 12.


H2O2 activates redox- and 4-aminopyridine-sensitive Kv channels in coronary vascular smooth muscle.

Rogers PA, Chilian WM, Bratz IN, Bryan RM Jr, Dick GM.

Am J Physiol Heart Circ Physiol. 2007 Mar;292(3):H1404-11. Epub 2006 Oct 27.


Hydrogen peroxide: a feed-forward dilator that couples myocardial metabolism to coronary blood flow.

Saitoh S, Zhang C, Tune JD, Potter B, Kiyooka T, Rogers PA, Knudson JD, Dick GM, Swafford A, Chilian WM.

Arterioscler Thromb Vasc Biol. 2006 Dec;26(12):2614-21. Epub 2006 Oct 5.


Resistin impairs endothelium-dependent dilation to bradykinin, but not acetylcholine, in the coronary circulation.

Dick GM, Katz PS, Farias M 3rd, Morris M, James J, Knudson JD, Tune JD.

Am J Physiol Heart Circ Physiol. 2006 Dec;291(6):H2997-3002. Epub 2006 Aug 11.


H2O2-induced redox-sensitive coronary vasodilation is mediated by 4-aminopyridine-sensitive K+ channels.

Rogers PA, Dick GM, Knudson JD, Focardi M, Bratz IN, Swafford AN Jr, Saitoh S, Tune JD, Chilian WM.

Am J Physiol Heart Circ Physiol. 2006 Nov;291(5):H2473-82. Epub 2006 Jun 2.


Coronary vasomotor reactivity to endothelin-1 in the prediabetic metabolic syndrome.

Knudson JD, Rogers PA, Dincer UD, Bratz IN, Araiza AG, Dick GM, Tune JD.

Microcirculation. 2006 Apr-May;13(3):209-18.


Leptin resistance extends to the coronary vasculature in prediabetic dogs and provides a protective adaptation against endothelial dysfunction.

Knudson JD, Dincer UD, Dick GM, Shibata H, Akahane R, Saito M, Tune JD.

Am J Physiol Heart Circ Physiol. 2005 Sep;289(3):H1038-46. Epub 2005 May 13.


Reduced functional expression of K(+) channels in vascular smooth muscle cells from rats made hypertensive with N{omega}-nitro-L-arginine.

Bratz IN, Swafford AN Jr, Kanagy NL, Dick GM.

Am J Physiol Heart Circ Physiol. 2005 Sep;289(3):H1284-90. Epub 2005 May 6.


Reduced molecular expression of K(+) channel proteins in vascular smooth muscle from rats made hypertensive with N{omega}-nitro-L-arginine.

Bratz IN, Dick GM, Partridge LD, Kanagy NL.

Am J Physiol Heart Circ Physiol. 2005 Sep;289(3):H1277-83. Epub 2005 Mar 25.


Leptin receptors are expressed in coronary arteries, and hyperleptinemia causes significant coronary endothelial dysfunction.

Knudson JD, Dincer UD, Zhang C, Swafford AN Jr, Koshida R, Picchi A, Focardi M, Dick GM, Tune JD.

Am J Physiol Heart Circ Physiol. 2005 Jul;289(1):H48-56. Epub 2005 Mar 4.


C-reactive protein does not relax vascular smooth muscle: effects mediated by sodium azide in commercially available preparations.

Swafford AN Jr, Bratz IN, Knudson JD, Rogers PA, Timmerman JM, Tune JD, Dick GM.

Am J Physiol Heart Circ Physiol. 2005 Apr;288(4):H1786-95. Epub 2004 Nov 24.


Phosphatidylinositol 3-kinase inhibitors reveal a unique mechanism of enhancing insulin secretion in 832/13 rat insulinoma cells.

Collier JJ, White SM, Dick GM, Scott DK.

Biochem Biophys Res Commun. 2004 Nov 19;324(3):1018-23.


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