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Items: 22


Alternative Translation Initiation Generates a Functionally Distinct Isoform of the Stress-Activated Protein Kinase MK2.

Trulley P, Snieckute G, Bekker-Jensen D, Menon MB, Freund R, Kotlyarov A, Olsen JV, Diaz-Muñoz MD, Turner M, Bekker-Jensen S, Gaestel M, Tiedje C.

Cell Rep. 2019 Jun 4;27(10):2859-2870.e6. doi: 10.1016/j.celrep.2019.05.024.


Uncovering the Role of RNA-Binding Proteins in Gene Expression in the Immune System.

Díaz-Muñoz MD, Turner M.

Front Immunol. 2018 May 23;9:1094. doi: 10.3389/fimmu.2018.01094. eCollection 2018. Review.


R-Ras2 is required for germinal center formation to aid B cells during energetically demanding processes.

Mendoza P, Martínez-Martín N, Bovolenta ER, Reyes-Garau D, Hernansanz-Agustín P, Delgado P, Diaz-Muñoz MD, Oeste CL, Fernández-Pisonero I, Castellano E, Martínez-Ruiz A, Alonso-Lopez D, Santos E, Bustelo XR, Kurosaki T, Alarcón B.

Sci Signal. 2018 May 29;11(532). pii: eaal1506. doi: 10.1126/scisignal.aal1506.


The RNA-binding protein PTBP1 is necessary for B cell selection in germinal centers.

Monzón-Casanova E, Screen M, Díaz-Muñoz MD, Coulson RMR, Bell SE, Lamers G, Solimena M, Smith CWJ, Turner M.

Nat Immunol. 2018 Mar;19(3):267-278. doi: 10.1038/s41590-017-0035-5. Epub 2018 Jan 22.


RNA-binding proteins control gene expression and cell fate in the immune system.

Turner M, Díaz-Muñoz MD.

Nat Immunol. 2018 Feb;19(2):120-129. doi: 10.1038/s41590-017-0028-4. Epub 2018 Jan 18. Review.


Tia1 dependent regulation of mRNA subcellular location and translation controls p53 expression in B cells.

Díaz-Muñoz MD, Kiselev VY, Le Novère N, Curk T, Ule J, Turner M.

Nat Commun. 2017 Sep 13;8(1):530. doi: 10.1038/s41467-017-00454-2.


Characterization of the B Cell Transcriptome Bound by RNA-Binding Proteins with iCLIP.

Díaz-Muñoz MD, Monzón-Casanova E, Turner M.

Methods Mol Biol. 2017;1623:159-179. doi: 10.1007/978-1-4939-7095-7_14.


The RNA-binding protein TTP is a global post-transcriptional regulator of feedback control in inflammation.

Tiedje C, Diaz-Muñoz MD, Trulley P, Ahlfors H, Laaß K, Blackshear PJ, Turner M, Gaestel M.

Nucleic Acids Res. 2016 Sep 6;44(15):7418-40. doi: 10.1093/nar/gkw474. Epub 2016 May 24.


RNA-binding proteins ZFP36L1 and ZFP36L2 promote cell quiescence.

Galloway A, Saveliev A, Łukasiak S, Hodson DJ, Bolland D, Balmanno K, Ahlfors H, Monzón-Casanova E, Mannurita SC, Bell LS, Andrews S, Díaz-Muñoz MD, Cook SJ, Corcoran A, Turner M.

Science. 2016 Apr 22;352(6284):453-9. doi: 10.1126/science.aad5978.


Dose-dependent effects of prostaglandin E2 in macrophage adhesion and migration.

Osma-Garcia IC, Punzón C, Fresno M, Díaz-Muñoz MD.

Eur J Immunol. 2016 Mar;46(3):677-88. doi: 10.1002/eji.201545629. Epub 2015 Dec 28.


Generation of functionally distinct isoforms of PTBP3 by alternative splicing and translation initiation.

Tan LY, Whitfield P, Llorian M, Monzon-Casanova E, Diaz-Munoz MD, Turner M, Smith CW.

Nucleic Acids Res. 2015 Jun 23;43(11):5586-600. doi: 10.1093/nar/gkv429. Epub 2015 May 4.


The RNA-binding protein HuR is essential for the B cell antibody response.

Diaz-Muñoz MD, Bell SE, Fairfax K, Monzon-Casanova E, Cunningham AF, Gonzalez-Porta M, Andrews SR, Bunik VI, Zarnack K, Curk T, Heggermont WA, Heymans S, Gibson GE, Kontoyiannis DL, Ule J, Turner M.

Nat Immunol. 2015 Apr;16(4):415-25. doi: 10.1038/ni.3115. Epub 2015 Feb 23.


Deletion of AU-rich elements within the Bcl2 3'UTR reduces protein expression and B cell survival in vivo.

Díaz-Muñoz MD, Bell SE, Turner M.

PLoS One. 2015 Feb 13;10(2):e0116899. doi: 10.1371/journal.pone.0116899. eCollection 2015.


Cyclooxygenase-2 deficiency in macrophages leads to defective p110γ PI3K signaling and impairs cell adhesion and migration.

Díaz-Muñoz MD, Osma-García IC, Iñiguez MA, Fresno M.

J Immunol. 2013 Jul 1;191(1):395-406. doi: 10.4049/jimmunol.1202002. Epub 2013 Jun 3.


Involvement of PGE2 and the cAMP signalling pathway in the up-regulation of COX-2 and mPGES-1 expression in LPS-activated macrophages.

Díaz-Muñoz MD, Osma-García IC, Fresno M, Iñiguez MA.

Biochem J. 2012 Apr 15;443(2):451-61. doi: 10.1042/BJ20111052.


Cyclooxygenase-independent inhibitory effects on T cell activation of novel 4,5-dihydro-3 trifluoromethyl pyrazole cyclooxygenase-2 inhibitors.

Iñiguez MA, Punzón C, Cacheiro-Llaguno C, Díaz-Muñoz MD, Duque J, Cuberes R, Alvarez I, Andrés EM, Buxens J, Buschmann H, Vela JM, Fresno M.

Int Immunopharmacol. 2010 Oct;10(10):1295-304. doi: 10.1016/j.intimp.2010.07.013. Epub 2010 Aug 10.


Coordinated up-regulation of cyclooxygenase-2 and microsomal prostaglandin E synthase 1 transcription by nuclear factor kappa B and early growth response-1 in macrophages.

Díaz-Muñoz MD, Osma-García IC, Cacheiro-Llaguno C, Fresno M, Iñiguez MA.

Cell Signal. 2010 Oct;22(10):1427-36. doi: 10.1016/j.cellsig.2010.05.011. Epub 2010 May 21.


A role for stroma-derived annexin A1 as mediator in the control of genetic susceptibility to T-cell lymphoblastic malignancies through prostaglandin E2 secretion.

Santos J, González-Sánchez L, Matabuena-Deyzaguirre M, Villa-Morales M, Cozar P, López-Nieva P, Fernández-Navarro P, Fresno M, Díaz-Muñoz MD, Guenet JL, Montagutelli X, Fernández-Piqueras J.

Cancer Res. 2009 Mar 15;69(6):2577-87. doi: 10.1158/0008-5472.CAN-08-1821. Epub 2009 Feb 24.


Role of peroxisome proliferator-activated receptor alpha in the control of cyclooxygenase 2 and vascular endothelial growth factor: involvement in tumor growth.

Grau R, Díaz-Muñoz MD, Cacheiro-Llaguno C, Fresno M, Iñiguez MA.

PPAR Res. 2008;2008:352437. doi: 10.1155/2008/352437.


Prostanoid function and cardiovascular disease.

Iñiguez MA, Cacheiro-Llaguno C, Cuesta N, Díaz-Muñoz MD, Fresno M.

Arch Physiol Biochem. 2008 Jul;114(3):201-9. doi: 10.1080/13813450802180882 . Review.


Requirement of tumor necrosis factor alpha and nuclear factor-kappaB in the induction by IFN-gamma of inducible nitric oxide synthase in macrophages.

Vila-del Sol V, Díaz-Muñoz MD, Fresno M.

J Leukoc Biol. 2007 Jan;81(1):272-83. Epub 2006 Oct 11.


Up-regulation of cyclooxygenase-2 by interleukin-1beta in colon carcinoma cells.

Duque J, Díaz-Muñoz MD, Fresno M, Iñiguez MA.

Cell Signal. 2006 Aug;18(8):1262-9. Epub 2005 Dec 2.


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