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Items: 1 to 50 of 96

1.

Glycosylated diphyllin as a broad-spectrum antiviral agent against Zika virus.

Martinez-Lopez A, Persaud M, Chavez MP, Zhang H, Rong L, Liu S, Wang TT, Sarafianos SG, Diaz-Griffero F.

EBioMedicine. 2019 Sep;47:269-283. doi: 10.1016/j.ebiom.2019.08.060. Epub 2019 Sep 6.

2.

SAMHD1 Modulates Early Steps during Human Cytomegalovirus Infection by Limiting NF-κB Activation.

Kim ET, Roche KL, Kulej K, Spruce LA, Seeholzer SH, Coen DM, Diaz-Griffero F, Murphy EA, Weitzman MD.

Cell Rep. 2019 Jul 9;28(2):434-448.e6. doi: 10.1016/j.celrep.2019.06.027.

3.

K63-Linked Ubiquitin Is Required for Restriction of HIV-1 Reverse Transcription and Capsid Destabilization by Rhesus TRIM5α.

Imam S, Kömürlü S, Mattick J, Selyutina A, Talley S, Eddins A, Diaz-Griffero F, Campbell EM.

J Virol. 2019 Jun 28;93(14). pii: e00558-19. doi: 10.1128/JVI.00558-19. Print 2019 Jul 15.

PMID:
31068426
4.

The ability of SAMHD1 to block HIV-1 but not SIV requires expression of MxB.

Buffone C, Kutzner J, Opp S, Martinez-Lopez A, Selyutina A, Coggings SA, Studdard LR, Ding L, Kim B, Spearman P, Schaller T, Diaz-Griffero F.

Virology. 2019 May;531:260-268. doi: 10.1016/j.virol.2019.03.018. Epub 2019 Mar 30.

5.

IL-15 regulates susceptibility of CD4+ T cells to HIV infection.

Manganaro L, Hong P, Hernandez MM, Argyle D, Mulder LCF, Potla U, Diaz-Griffero F, Lee B, Fernandez-Sesma A, Simon V.

Proc Natl Acad Sci U S A. 2018 Oct 9;115(41):E9659-E9667. doi: 10.1073/pnas.1806695115. Epub 2018 Sep 26.

6.

SAMHD1 deficient human monocytes autonomously trigger type I interferon.

Martinez-Lopez A, Martin-Fernandez M, Buta S, Kim B, Bogunovic D, Diaz-Griffero F.

Mol Immunol. 2018 Sep;101:450-460. doi: 10.1016/j.molimm.2018.08.005. Epub 2018 Aug 9.

7.

Binding of host factors to stabilized HIV-1 capsid tubes.

Selyutina A, Bulnes-Ramos A, Diaz-Griffero F.

Virology. 2018 Oct;523:1-5. doi: 10.1016/j.virol.2018.07.019. Epub 2018 Jul 26.

8.

Functionality of Redox-Active Cysteines Is Required for Restriction of Retroviral Replication by SAMHD1.

Wang Z, Bhattacharya A, White T, Buffone C, McCabe A, Nguyen LA, Shepard CN, Pardo S, Kim B, Weintraub ST, Demeler B, Diaz-Griffero F, Ivanov DN.

Cell Rep. 2018 Jul 24;24(4):815-823. doi: 10.1016/j.celrep.2018.06.090.

9.

Immune Responses to RNA Viruses.

Said EA, Diaz-Griffero F, Bonte D, Lamarre D, Al-Jabri AA.

J Immunol Res. 2018 Jun 12;2018:5473678. doi: 10.1155/2018/5473678. eCollection 2018. No abstract available.

10.

Nup153 Unlocks the Nuclear Pore Complex for HIV-1 Nuclear Translocation in Nondividing Cells.

Buffone C, Martinez-Lopez A, Fricke T, Opp S, Severgnini M, Cifola I, Petiti L, Frabetti S, Skorupka K, Zadrozny KK, Ganser-Pornillos BK, Pornillos O, Di Nunzio F, Diaz-Griffero F.

J Virol. 2018 Sep 12;92(19). pii: e00648-18. doi: 10.1128/JVI.00648-18. Print 2018 Oct 1.

11.

Dephosphorylation of the HIV-1 restriction factor SAMHD1 is mediated by PP2A-B55α holoenzymes during mitotic exit.

Schott K, Fuchs NV, Derua R, Mahboubi B, Schnellbächer E, Seifried J, Tondera C, Schmitz H, Shepard C, Brandariz-Nuñez A, Diaz-Griffero F, Reuter A, Kim B, Janssens V, König R.

Nat Commun. 2018 Jun 8;9(1):2227. doi: 10.1038/s41467-018-04671-1.

12.

Correction: Species-specific vulnerability of RanBP2 shaped the evolution of SIV as it transmitted in African apes.

Meyerson NR, Warren CJ, Vieira DASA, Diaz-Griffero F, Sawyer SL.

PLoS Pathog. 2018 Apr 3;14(4):e1006983. doi: 10.1371/journal.ppat.1006983. eCollection 2018 Apr.

13.

Infection by Zika viruses requires the transmembrane protein AXL, endocytosis and low pH.

Persaud M, Martinez-Lopez A, Buffone C, Porcelli SA, Diaz-Griffero F.

Virology. 2018 May;518:301-312. doi: 10.1016/j.virol.2018.03.009. Epub 2018 Mar 22.

14.

Localization to detergent-resistant membranes and HIV-1 core entry inhibition correlate with HIV-1 restriction by SERINC5.

Schulte B, Selyutina A, Opp S, Herschhorn A, Sodroski JG, Pizzato M, Diaz-Griffero F.

Virology. 2018 Feb;515:52-65. doi: 10.1016/j.virol.2017.12.005. Epub 2017 Dec 18.

15.

Correction for Fricke et al., "Human Cytosolic Extracts Stabilize the HIV-1 Core".

Fricke T, Brandariz-Nuñez A, Wang X, Smith AB 3rd, Diaz-Griffero F.

J Virol. 2017 Nov 30;91(24). pii: e01732-17. doi: 10.1128/JVI.01732-17. Print 2017 Dec 15. No abstract available.

16.

Bicaudal D2 facilitates the cytoplasmic trafficking and nuclear import of HIV-1 genomes during infection.

Dharan A, Opp S, Abdel-Rahim O, Keceli SK, Imam S, Diaz-Griffero F, Campbell EM.

Proc Natl Acad Sci U S A. 2017 Dec 12;114(50):E10707-E10716. doi: 10.1073/pnas.1712033114. Epub 2017 Nov 27.

17.

A SAMHD1 mutation associated with Aicardi-Goutières syndrome uncouples the ability of SAMHD1 to restrict HIV-1 from its ability to downmodulate type I interferon in humans.

White TE, Brandariz-Nuñez A, Martinez-Lopez A, Knowlton C, Lenzi G, Kim B, Ivanov D, Diaz-Griffero F.

Hum Mutat. 2017 Jun;38(6):658-668. doi: 10.1002/humu.23201. Epub 2017 May 2.

18.

The small-molecule 3G11 inhibits HIV-1 reverse transcription.

Opp S, Fricke T, Shepard C, Kovalskyy D, Bhattacharya A, Herkules F, Ivanov DN, Kim B, Valle-Casuso J, Diaz-Griffero F.

Chem Biol Drug Des. 2017 Apr;89(4):608-618. doi: 10.1111/cbdd.12886. Epub 2016 Nov 15.

19.
20.

Effects of T592 phosphomimetic mutations on tetramer stability and dNTPase activity of SAMHD1 can not explain the retroviral restriction defect.

Bhattacharya A, Wang Z, White T, Buffone C, Nguyen LA, Shepard CN, Kim B, Demeler B, Diaz-Griffero F, Ivanov DN.

Sci Rep. 2016 Aug 11;6:31353. doi: 10.1038/srep31353.

21.

Modulation of LINE-1 Retrotransposition by a Human SAMHD1 Polymorphism.

White TE, Brandariz-Nuñez A, Han K, Sawyer SL, Kim B, Diaz-Griffero F.

Virol Rep. 2016 Dec;6:53-60.

22.

A putative SUMO interacting motif in the B30.2/SPRY domain of rhesus macaque TRIM5α important for NF-κB/AP-1 signaling and HIV-1 restriction.

Nepveu-Traversy MÉ, Demogines A, Fricke T, Plourde MB, Riopel K, Veillette M, Diaz-Griffero F, Sawyer SL, Berthoux L.

Heliyon. 2016 Jan 21;2(1):e00056. doi: 10.1016/j.heliyon.2015.e00056. eCollection 2016 Jan.

23.

HIV-1 capsid is involved in post-nuclear entry steps.

Chen NY, Zhou L, Gane PJ, Opp S, Ball NJ, Nicastro G, Zufferey M, Buffone C, Luban J, Selwood D, Diaz-Griffero F, Taylor I, Fassati A.

Retrovirology. 2016 Apr 23;13:28. doi: 10.1186/s12977-016-0262-0.

24.

SUN2 Overexpression Deforms Nuclear Shape and Inhibits HIV.

Donahue DA, Amraoui S, di Nunzio F, Kieffer C, Porrot F, Opp S, Diaz-Griffero F, Casartelli N, Schwartz O.

J Virol. 2016 Mar 28;90(8):4199-4214. doi: 10.1128/JVI.03202-15. Print 2016 Apr.

25.

Ebselen, a Small-Molecule Capsid Inhibitor of HIV-1 Replication.

Thenin-Houssier S, de Vera IM, Pedro-Rosa L, Brady A, Richard A, Konnick B, Opp S, Buffone C, Fuhrmann J, Kota S, Billack B, Pietka-Ottlik M, Tellinghuisen T, Choe H, Spicer T, Scampavia L, Diaz-Griffero F, Kojetin DJ, Valente ST.

Antimicrob Agents Chemother. 2016 Mar 25;60(4):2195-208. doi: 10.1128/AAC.02574-15. Print 2016 Apr.

26.

MxB Is Not Responsible for the Blocking of HIV-1 Infection Observed in Alpha Interferon-Treated Cells.

Opp S, Vieira DA, Schulte B, Chanda SK, Diaz-Griffero F.

J Virol. 2015 Dec 30;90(6):3056-64. doi: 10.1128/JVI.03146-15.

27.

HIV-1 Capsid Stabilization Assay.

Fricke T, Diaz-Griffero F.

Methods Mol Biol. 2016;1354:39-47. doi: 10.1007/978-1-4939-3046-3_3.

PMID:
26714703
28.

TRIM5α-Mediated Ubiquitin Chain Conjugation Is Required for Inhibition of HIV-1 Reverse Transcription and Capsid Destabilization.

Campbell EM, Weingart J, Sette P, Opp S, Sastri J, O'Connor SK, Talley S, Diaz-Griffero F, Hirsch V, Bouamr F.

J Virol. 2015 Dec 16;90(4):1849-57. doi: 10.1128/JVI.01948-15. Print 2016 Feb 15.

29.

RING Dimerization Links Higher-Order Assembly of TRIM5α to Synthesis of K63-Linked Polyubiquitin.

Yudina Z, Roa A, Johnson R, Biris N, de Souza Aranha Vieira DA, Tsiperson V, Reszka N, Taylor AB, Hart PJ, Demeler B, Diaz-Griffero F, Ivanov DN.

Cell Rep. 2015 Aug 4;12(5):788-97. doi: 10.1016/j.celrep.2015.06.072. Epub 2015 Jul 23.

30.

Complement-Opsonized HIV-1 Overcomes Restriction in Dendritic Cells.

Posch W, Steger M, Knackmuss U, Blatzer M, Baldauf HM, Doppler W, White TE, Hörtnagl P, Diaz-Griffero F, Lass-Flörl C, Hackl H, Moris A, Keppler OT, Wilflingseder D.

PLoS Pathog. 2015 Jun 29;11(6):e1005005. doi: 10.1371/journal.ppat.1005005. eCollection 2015 Jun.

31.

Restriction of HIV-1 Requires the N-Terminal Region of MxB as a Capsid-Binding Motif but Not as a Nuclear Localization Signal.

Schulte B, Buffone C, Opp S, Di Nunzio F, De Souza Aranha Vieira DA, Brandariz-Nuñez A, Diaz-Griffero F.

J Virol. 2015 Aug;89(16):8599-610. doi: 10.1128/JVI.00753-15. Epub 2015 Jun 10.

32.

HIV-1 capsids bind and exploit the kinesin-1 adaptor FEZ1 for inward movement to the nucleus.

Malikov V, da Silva ES, Jovasevic V, Bennett G, de Souza Aranha Vieira DA, Schulte B, Diaz-Griffero F, Walsh D, Naghavi MH.

Nat Commun. 2015 Mar 30;6:6660. doi: 10.1038/ncomms7660.

33.

Chromatin organization at the nuclear pore favours HIV replication.

Lelek M, Casartelli N, Pellin D, Rizzi E, Souque P, Severgnini M, Di Serio C, Fricke T, Diaz-Griffero F, Zimmer C, Charneau P, Di Nunzio F.

Nat Commun. 2015 Mar 6;6:6483. doi: 10.1038/ncomms7483.

34.

Contribution of MxB oligomerization to HIV-1 capsid binding and restriction.

Buffone C, Schulte B, Opp S, Diaz-Griffero F.

J Virol. 2015 Mar;89(6):3285-94. doi: 10.1128/JVI.03730-14. Epub 2015 Jan 7.

35.

Structural basis of HIV-1 capsid recognition by PF74 and CPSF6.

Bhattacharya A, Alam SL, Fricke T, Zadrozny K, Sedzicki J, Taylor AB, Demeler B, Pornillos O, Ganser-Pornillos BK, Diaz-Griffero F, Ivanov DN, Yeager M.

Proc Natl Acad Sci U S A. 2014 Dec 30;111(52):18625-30. doi: 10.1073/pnas.1419945112. Epub 2014 Dec 17.

36.

BI-2 destabilizes HIV-1 cores during infection and Prevents Binding of CPSF6 to the HIV-1 Capsid.

Fricke T, Buffone C, Opp S, Valle-Casuso J, Diaz-Griffero F.

Retrovirology. 2014 Dec 11;11:120. doi: 10.1186/s12977-014-0120-x.

37.

HIV-1 uncoating is facilitated by dynein and kinesin 1.

Lukic Z, Dharan A, Fricke T, Diaz-Griffero F, Campbell EM.

J Virol. 2014 Dec;88(23):13613-25. doi: 10.1128/JVI.02219-14. Epub 2014 Sep 17.

38.

dNTP pool modulation dynamics by SAMHD1 protein in monocyte-derived macrophages.

Hollenbaugh JA, Tao S, Lenzi GM, Ryu S, Kim DH, Diaz-Griffero F, Schinazi RF, Kim B.

Retrovirology. 2014 Aug 27;11:63. doi: 10.1186/s12977-014-0063-2.

39.

MxB binds to the HIV-1 core and prevents the uncoating process of HIV-1.

Fricke T, White TE, Schulte B, de Souza Aranha Vieira DA, Dharan A, Campbell EM, Brandariz-Nuñez A, Diaz-Griffero F.

Retrovirology. 2014 Aug 14;11:68. doi: 10.1186/s12977-014-0068-x.

40.

The ribonuclease activity of SAMHD1 is required for HIV-1 restriction.

Ryoo J, Choi J, Oh C, Kim S, Seo M, Kim SY, Seo D, Kim J, White TE, Brandariz-Nuñez A, Diaz-Griffero F, Yun CH, Hollenbaugh JA, Kim B, Baek D, Ahn K.

Nat Med. 2014 Aug;20(8):936-41. doi: 10.1038/nm.3626. Epub 2014 Jul 20.

41.

Effects of human SAMHD1 polymorphisms on HIV-1 susceptibility.

White TE, Brandariz-Nuñez A, Valle-Casuso JC, Knowlton C, Kim B, Sawyer SL, Diaz-Griffero F.

Virology. 2014 Jul;460-461:34-44. doi: 10.1016/j.virol.2014.04.023. Epub 2014 May 29.

42.

A proteolytic cascade controls lysosome rupture and necrotic cell death mediated by lysosome-destabilizing adjuvants.

Brojatsch J, Lima H, Kar AK, Jacobson LS, Muehlbauer SM, Chandran K, Diaz-Griffero F.

PLoS One. 2014 Jun 3;9(6):e95032. doi: 10.1371/journal.pone.0095032. eCollection 2014.

43.

Restriction of HIV-1 by rhesus TRIM5α is governed by alpha helices in the Linker2 region.

Sastri J, Johnsen L, Smolin N, Imam S, Mukherjee S, Lukic Z, Brandariz-Nuñez A, Robia SL, Diaz-Griffero F, Wiethoff C, Campbell EM.

J Virol. 2014 Aug;88(16):8911-23. doi: 10.1128/JVI.01134-14. Epub 2014 May 28.

44.

Identification of cellular proteins interacting with the retroviral restriction factor SAMHD1.

St Gelais C, de Silva S, Hach JC, White TE, Diaz-Griffero F, Yount JS, Wu L.

J Virol. 2014 May;88(10):5834-44. doi: 10.1128/JVI.00155-14. Epub 2014 Mar 12. Erratum in: J Virol. 2014 Jul;88(13):7689.

45.

Binding of the rhesus TRIM5α PRYSPRY domain to capsid is necessary but not sufficient for HIV-1 restriction.

Yang Y, Brandariz-Nuñez A, Fricke T, Ivanov DN, Sarnak Z, Diaz-Griffero F.

Virology. 2014 Jan 5;448:217-28. doi: 10.1016/j.virol.2013.10.012. Epub 2013 Oct 31.

46.

Contribution of oligomerization to the anti-HIV-1 properties of SAMHD1.

Brandariz-Nuñez A, Valle-Casuso JC, White TE, Nguyen L, Bhattacharya A, Wang Z, Demeler B, Amie S, Knowlton C, Kim B, Ivanov DN, Diaz-Griffero F.

Retrovirology. 2013 Nov 12;10:131. doi: 10.1186/1742-4690-10-131.

47.

The fate of HIV-1 capsid: a biochemical assay for HIV-1 uncoating.

Yang Y, Luban J, Diaz-Griffero F.

Methods Mol Biol. 2014;1087:29-36. doi: 10.1007/978-1-62703-670-2_3.

48.

Preferential lentiviral targeting of astrocytes in the central nervous system.

Fassler M, Weissberg I, Levy N, Diaz-Griffero F, Monsonego A, Friedman A, Taube R.

PLoS One. 2013 Oct 2;8(10):e76092. doi: 10.1371/journal.pone.0076092. eCollection 2013.

49.

SAMHD1 restricts herpes simplex virus 1 in macrophages by limiting DNA replication.

Kim ET, White TE, Brandariz-Núñez A, Diaz-Griffero F, Weitzman MD.

J Virol. 2013 Dec;87(23):12949-56. doi: 10.1128/JVI.02291-13. Epub 2013 Sep 25.

50.

Rhesus monkey TRIM5α SPRY domain recognizes multiple epitopes that span several capsid monomers on the surface of the HIV-1 mature viral core.

Biris N, Tomashevski A, Bhattacharya A, Diaz-Griffero F, Ivanov DN.

J Mol Biol. 2013 Dec 13;425(24):5032-44. doi: 10.1016/j.jmb.2013.07.025. Epub 2013 Jul 23.

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