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Items: 1 to 50 of 371

1.

Dengue and Zika Virus Cross-Reactive Human Monoclonal Antibodies Protect against Spondweni Virus Infection and Pathogenesis in Mice.

Salazar V, Jagger BW, Mongkolsapaya J, Burgomaster KE, Dejnirattisai W, Winkler ES, Fernandez E, Nelson CA, Fremont DH, Pierson TC, Crowe JE Jr, Screaton GR, Diamond MS.

Cell Rep. 2019 Feb 5;26(6):1585-1597.e4. doi: 10.1016/j.celrep.2019.01.052.

2.

Interferon lambda protects the female reproductive tract against Zika virus infection.

Caine EA, Scheaffer SM, Arora N, Zaitsev K, Artyomov MN, Coyne CB, Moley KH, Diamond MS.

Nat Commun. 2019 Jan 17;10(1):280. doi: 10.1038/s41467-018-07993-2.

3.

Structural basis of a potent human monoclonal antibody against Zika virus targeting a quaternary epitope.

Long F, Doyle M, Fernandez E, Miller AS, Klose T, Sevvana M, Bryan A, Davidson E, Doranz BJ, Kuhn RJ, Diamond MS, Crowe JE Jr, Rossmann MG.

Proc Natl Acad Sci U S A. 2019 Jan 29;116(5):1591-1596. doi: 10.1073/pnas.1815432116. Epub 2019 Jan 14.

PMID:
30642974
4.

Immune responses at the maternal-fetal interface.

Ander SE, Diamond MS, Coyne CB.

Sci Immunol. 2019 Jan 11;4(31). pii: eaat6114. doi: 10.1126/sciimmunol.aat6114. Review.

PMID:
30635356
5.

Efficacy of a T Cell-Biased Adenovirus Vector as a Zika Virus Vaccine.

Bullard BL, Corder BN, Gorman MJ, Diamond MS, Weaver EA.

Sci Rep. 2018 Dec 20;8(1):18017. doi: 10.1038/s41598-018-35755-z.

6.

An mRNA Vaccine Protects Mice against Multiple Tick-Transmitted Flavivirus Infections.

VanBlargan LA, Himansu S, Foreman BM, Ebel GD, Pierson TC, Diamond MS.

Cell Rep. 2018 Dec 18;25(12):3382-3392.e3. doi: 10.1016/j.celrep.2018.11.082.

7.

Cryo-EM Structures of Eastern Equine Encephalitis Virus Reveal Mechanisms of Virus Disassembly and Antibody Neutralization.

Hasan SS, Sun C, Kim AS, Watanabe Y, Chen CL, Klose T, Buda G, Crispin M, Diamond MS, Klimstra WB, Rossmann MG.

Cell Rep. 2018 Dec 11;25(11):3136-3147.e5. doi: 10.1016/j.celrep.2018.11.067.

8.

A protective human monoclonal antibody targeting the West Nile virus E protein preferentially recognizes mature virions.

Goo L, Debbink K, Kose N, Sapparapu G, Doyle MP, Wessel AW, Richner JM, Burgomaster KE, Larman BC, Dowd KA, Diamond MS, Crowe JE Jr, Pierson TC.

Nat Microbiol. 2019 Jan;4(1):71-77. doi: 10.1038/s41564-018-0283-7. Epub 2018 Nov 19.

PMID:
30455471
9.

Protective antibodies against Eastern equine encephalitis virus bind to epitopes in domains A and B of the E2 glycoprotein.

Kim AS, Austin SK, Gardner CL, Zuiani A, Reed DS, Trobaugh DW, Sun C, Basore K, Williamson LE, Crowe JE Jr, Slifka MK, Fremont DH, Klimstra WB, Diamond MS.

Nat Microbiol. 2019 Jan;4(1):187-197. doi: 10.1038/s41564-018-0286-4. Epub 2018 Nov 19.

PMID:
30455470
10.

Maternally Acquired Zika Antibodies Enhance Dengue Disease Severity in Mice.

Fowler AM, Tang WW, Young MP, Mamidi A, Viramontes KM, McCauley MD, Carlin AF, Schooley RT, Swanstrom J, Baric RS, Govero J, Diamond MS, Shresta S.

Cell Host Microbe. 2018 Nov 14;24(5):743-750.e5. doi: 10.1016/j.chom.2018.09.015.

PMID:
30439343
11.

WDFY4 is required for cross-presentation in response to viral and tumor antigens.

Theisen DJ, Davidson JT 4th, Briseño CG, Gargaro M, Lauron EJ, Wang Q, Desai P, Durai V, Bagadia P, Brickner JR, Beatty WL, Virgin HW, Gillanders WE, Mosammaparast N, Diamond MS, Sibley LD, Yokoyama W, Schreiber RD, Murphy TL, Murphy KM.

Science. 2018 Nov 9;362(6415):694-699. doi: 10.1126/science.aat5030.

PMID:
30409884
12.

Zika Virus Vaccine Development: Progress in the Face of New Challenges.

Diamond MS, Ledgerwood JE, Pierson TC.

Annu Rev Med. 2019 Jan 27;70:121-135. doi: 10.1146/annurev-med-040717-051127. Epub 2018 Nov 2.

PMID:
30388054
13.

Animal Models of Zika Virus Infection during Pregnancy.

Caine EA, Jagger BW, Diamond MS.

Viruses. 2018 Oct 31;10(11). pii: E598. doi: 10.3390/v10110598. Review.

14.

Intestinal Dysmotility Syndromes following Systemic Infection by Flaviviruses.

White JP, Xiong S, Malvin NP, Khoury-Hanold W, Heuckeroth RO, Stappenbeck TS, Diamond MS.

Cell. 2018 Nov 15;175(5):1198-1212.e12. doi: 10.1016/j.cell.2018.08.069. Epub 2018 Oct 4.

PMID:
30293866
15.

The Interferon-Induced Exonuclease ISG20 Exerts Antiviral Activity through Upregulation of Type I Interferon Response Proteins.

Weiss CM, Trobaugh DW, Sun C, Lucas TM, Diamond MS, Ryman KD, Klimstra WB.

mSphere. 2018 Sep 19;3(5). pii: e00209-18. doi: 10.1128/mSphere.00209-18.

16.

The emergence of Zika virus and its new clinical syndromes.

Pierson TC, Diamond MS.

Nature. 2018 Aug;560(7720):573-581. doi: 10.1038/s41586-018-0446-y. Epub 2018 Aug 29. Review.

PMID:
30158602
17.

Antigen-specific antibody Fc glycosylation enhances humoral immunity via the recruitment of complement.

Lofano G, Gorman MJ, Yousif AS, Yu WH, Fox JM, Dugast AS, Ackerman ME, Suscovich TJ, Weiner J, Barouch D, Streeck H, Little S, Smith D, Richman D, Lauffenburger D, Walker BD, Diamond MS, Alter G.

Sci Immunol. 2018 Aug 17;3(26). pii: eaat7796. doi: 10.1126/sciimmunol.aat7796.

18.

Cross-reactive Dengue virus-specific CD8+ T cells protect against Zika virus during pregnancy.

Regla-Nava JA, Elong Ngono A, Viramontes KM, Huynh AT, Wang YT, Nguyen AT, Salgado R, Mamidi A, Kim K, Diamond MS, Shresta S.

Nat Commun. 2018 Aug 2;9(1):3042. doi: 10.1038/s41467-018-05458-0.

19.

Engineered Dengue Virus Domain III Proteins Elicit Cross-Neutralizing Antibody Responses in Mice.

Frei JC, Wirchnianski AS, Govero J, Vergnolle O, Dowd KA, Pierson TC, Kielian M, Girvin ME, Diamond MS, Lai JR.

J Virol. 2018 Aug 29;92(18). pii: e01023-18. doi: 10.1128/JVI.01023-18. Print 2018 Sep 15.

PMID:
29976679
20.

Mxra8 is a receptor for multiple arthritogenic alphaviruses.

Zhang R, Kim AS, Fox JM, Nair S, Basore K, Klimstra WB, Rimkunas R, Fong RH, Lin H, Poddar S, Crowe JE Jr, Doranz BJ, Fremont DH, Diamond MS.

Nature. 2018 May;557(7706):570-574. doi: 10.1038/s41586-018-0121-3. Epub 2018 May 16.

21.

Zika virus vaccines: immune response, current status, and future challenges.

Richner JM, Diamond MS.

Curr Opin Immunol. 2018 Aug;53:130-136. doi: 10.1016/j.coi.2018.04.024. Epub 2018 May 10. Review.

PMID:
29753210
22.

An Immunocompetent Mouse Model of Zika Virus Infection.

Gorman MJ, Caine EA, Zaitsev K, Begley MC, Weger-Lucarelli J, Uccellini MB, Tripathi S, Morrison J, Yount BL, Dinnon KH 3rd, Rückert C, Young MC, Zhu Z, Robertson SJ, McNally KL, Ye J, Cao B, Mysorekar IU, Ebel GD, Baric RS, Best SM, Artyomov MN, Garcia-Sastre A, Diamond MS.

Cell Host Microbe. 2018 May 9;23(5):672-685.e6. doi: 10.1016/j.chom.2018.04.003.

PMID:
29746837
23.

Oral Antibiotic Treatment of Mice Exacerbates the Disease Severity of Multiple Flavivirus Infections.

Thackray LB, Handley SA, Gorman MJ, Poddar S, Bagadia P, Briseño CG, Theisen DJ, Tan Q, Hykes BL Jr, Lin H, Lucas TM, Desai C, Gordon JI, Murphy KM, Virgin HW, Diamond MS.

Cell Rep. 2018 Mar 27;22(13):3440-3453.e6. doi: 10.1016/j.celrep.2018.03.001.

24.

Human IFIT3 Modulates IFIT1 RNA Binding Specificity and Protein Stability.

Johnson B, VanBlargan LA, Xu W, White JP, Shan C, Shi PY, Zhang R, Adhikari J, Gross ML, Leung DW, Diamond MS, Amarasinghe GK.

Immunity. 2018 Mar 20;48(3):487-499.e5. doi: 10.1016/j.immuni.2018.01.014. Epub 2018 Mar 8.

25.

Irg1 expression in myeloid cells prevents immunopathology during M. tuberculosis infection.

Nair S, Huynh JP, Lampropoulou V, Loginicheva E, Esaulova E, Gounder AP, Boon ACM, Schwarzkopf EA, Bradstreet TR, Edelson BT, Artyomov MN, Stallings CL, Diamond MS.

J Exp Med. 2018 Apr 2;215(4):1035-1045. doi: 10.1084/jem.20180118. Epub 2018 Mar 6.

26.

Mouse and Human Monoclonal Antibodies Protect against Infection by Multiple Genotypes of Japanese Encephalitis Virus.

Fernandez E, Kose N, Edeling MA, Adhikari J, Sapparapu G, Lazarte SM, Nelson CA, Govero J, Gross ML, Fremont DH, Crowe JE Jr, Diamond MS.

MBio. 2018 Feb 27;9(1). pii: e00008-18. doi: 10.1128/mBio.00008-18.

27.

Zika virus-related neurotropic flaviviruses infect human placental explants and cause fetal demise in mice.

Platt DJ, Smith AM, Arora N, Diamond MS, Coyne CB, Miner JJ.

Sci Transl Med. 2018 Jan 31;10(426). pii: eaao7090. doi: 10.1126/scitranslmed.aao7090.

28.

Structural Study of the C-Terminal Domain of Nonstructural Protein 1 from Japanese Encephalitis Virus.

Poonsiri T, Wright GSA, Diamond MS, Turtle L, Solomon T, Antonyuk SV.

J Virol. 2018 Mar 14;92(7). pii: e01868-17. doi: 10.1128/JVI.01868-17. Print 2018 Apr 1.

29.

Cellular and Humoral Immunity Protect against Vaginal Zika Virus Infection in Mice.

Scott JM, Lebratti TJ, Richner JM, Jiang X, Fernandez E, Zhao H, Fremont DH, Diamond MS, Shin H.

J Virol. 2018 Jan 17. pii: JVI.00038-18. doi: 10.1128/JVI.00038-18. [Epub ahead of print]

30.

Vaccines in 2017: Closing in on a Zika virus vaccine.

Diamond MS, Coyne CB.

Nat Rev Immunol. 2018 Feb;18(2):89-90. doi: 10.1038/nri.2017.132. Epub 2017 Dec 4. No abstract available.

PMID:
29199280
31.

Protection of mice deficient in mature B cells from West Nile virus infection by passive and active immunization.

Giordano D, Draves KE, Young LB, Roe K, Bryan MA, Dresch C, Richner JM, Diamond MS, Gale M Jr, Clark EA.

PLoS Pathog. 2017 Nov 27;13(11):e1006743. doi: 10.1371/journal.ppat.1006743. eCollection 2017 Nov.

32.

Dengue virus-reactive CD8+ T cells mediate cross-protection against subsequent Zika virus challenge.

Wen J, Elong Ngono A, Regla-Nava JA, Kim K, Gorman MJ, Diamond MS, Shresta S.

Nat Commun. 2017 Nov 13;8(1):1459. doi: 10.1038/s41467-017-01669-z.

33.

An IRF-3-, IRF-5-, and IRF-7-Independent Pathway of Dengue Viral Resistance Utilizes IRF-1 to Stimulate Type I and II Interferon Responses.

Carlin AF, Plummer EM, Vizcarra EA, Sheets N, Joo Y, Tang W, Day J, Greenbaum J, Glass CK, Diamond MS, Shresta S.

Cell Rep. 2017 Nov 7;21(6):1600-1612. doi: 10.1016/j.celrep.2017.10.054.

34.

Influenza virus differentially activates mTORC1 and mTORC2 signaling to maximize late stage replication.

Kuss-Duerkop SK, Wang J, Mena I, White K, Metreveli G, Sakthivel R, Mata MA, Muñoz-Moreno R, Chen X, Krammer F, Diamond MS, Chen ZJ, García-Sastre A, Fontoura BMA.

PLoS Pathog. 2017 Sep 27;13(9):e1006635. doi: 10.1371/journal.ppat.1006635. eCollection 2017 Sep.

35.

Human antibodies to the dengue virus E-dimer epitope have therapeutic activity against Zika virus infection.

Fernandez E, Dejnirattisai W, Cao B, Scheaffer SM, Supasa P, Wongwiwat W, Esakky P, Drury A, Mongkolsapaya J, Moley KH, Mysorekar IU, Screaton GR, Diamond MS.

Nat Immunol. 2017 Nov;18(11):1261-1269. doi: 10.1038/ni.3849. Epub 2017 Sep 25.

36.

A single-dose live-attenuated vaccine prevents Zika virus pregnancy transmission and testis damage.

Shan C, Muruato AE, Jagger BW, Richner J, Nunes BTD, Medeiros DBA, Xie X, Nunes JGC, Morabito KM, Kong WP, Pierson TC, Barrett AD, Weaver SC, Rossi SL, Vasconcelos PFC, Graham BS, Diamond MS, Shi PY.

Nat Commun. 2017 Sep 22;8(1):676. doi: 10.1038/s41467-017-00737-8.

37.

Correction: Zika virus has oncolytic activity against glioblastoma stem cells.

Zhu Z, Gorman MJ, McKenzie LD, Chai JN, Hubert CG, Prager BC, Fernandez E, Richner JM, Zhang R, Shan C, Tycksen E, Wang X, Shi PY, Diamond MS, Rich JN, Chheda MG.

J Exp Med. 2017 Oct 2;214(10):3145. doi: 10.1084/jem.2017109309122017c. Epub 2017 Sep 15. No abstract available.

38.

Gestational Stage and IFN-λ Signaling Regulate ZIKV Infection In Utero.

Jagger BW, Miner JJ, Cao B, Arora N, Smith AM, Kovacs A, Mysorekar IU, Coyne CB, Diamond MS.

Cell Host Microbe. 2017 Sep 13;22(3):366-376.e3. doi: 10.1016/j.chom.2017.08.012.

39.

Zika virus has oncolytic activity against glioblastoma stem cells.

Zhu Z, Gorman MJ, McKenzie LD, Chai JN, Hubert CG, Prager BC, Fernandez E, Richner JM, Zhang R, Shan C, Tycksen E, Wang X, Shi PY, Diamond MS, Rich JN, Chheda MG.

J Exp Med. 2017 Oct 2;214(10):2843-2857. doi: 10.1084/jem.20171093. Epub 2017 Sep 5. Erratum in: J Exp Med. 2017 Sep 15;:.

40.

Interferon regulatory factor-1 (IRF-1) protects against chikungunya virus induced immunopathology by restricting infection in muscle cells.

Nair S, Poddar S, Shimak RM, Diamond MS.

J Virol. 2017 Aug 23. pii: JVI.01419-17. doi: 10.1128/JVI.01419-17. [Epub ahead of print]

41.

MUTATIONS IN THE E2 GLYCOPROTEIN AND THE 3' UNTRANSLATED REGION ENHANCE CHIKUNGUNYA VIRUS VIRULENCE IN MICE.

Hawman DW, Carpentier KS, Fox JM, May NA, Sanders W, Montgomery SA, Moorman NJ, Diamond MS, Morrison TE.

J Virol. 2017 Jul 26. pii: JVI.00816-17. doi: 10.1128/JVI.00816-17. [Epub ahead of print]

42.

Vaccine Mediated Protection Against Zika Virus-Induced Congenital Disease.

Richner JM, Jagger BW, Shan C, Fontes CR, Dowd KA, Cao B, Himansu S, Caine EA, Nunes BTD, Medeiros DBA, Muruato AE, Foreman BM, Luo H, Wang T, Barrett AD, Weaver SC, Vasconcelos PFC, Rossi SL, Ciaramella G, Mysorekar IU, Pierson TC, Shi PY, Diamond MS.

Cell. 2017 Jul 13;170(2):273-283.e12. doi: 10.1016/j.cell.2017.06.040.

43.

Inhibition of autophagy limits vertical transmission of Zika virus in pregnant mice.

Cao B, Parnell LA, Diamond MS, Mysorekar IU.

J Exp Med. 2017 Aug 7;214(8):2303-2313. doi: 10.1084/jem.20170957. Epub 2017 Jul 10.

44.

Therapeutic administration of a recombinant human monoclonal antibody reduces the severity of chikungunya virus disease in rhesus macaques.

Broeckel R, Fox JM, Haese N, Kreklywich CN, Sukulpovi-Petty S, Legasse A, Smith PP, Denton M, Corvey C, Krishnan S, Colgin LMA, Ducore RM, Lewis AD, Axthelm MK, Mandron M, Cortez P, Rothblatt J, Rao E, Focken I, Carter K, Sapparapau G, Crowe JE Jr, Diamond MS, Streblow DN.

PLoS Negl Trop Dis. 2017 Jun 19;11(6):e0005637. doi: 10.1371/journal.pntd.0005637. eCollection 2017 Jun.

45.

Dengue Antibodies, then Zika: A Fatal Sequence in Mice.

Miner JJ, Diamond MS.

Immunity. 2017 May 16;46(5):771-773. doi: 10.1016/j.immuni.2017.04.023.

46.

Plasmodium falciparum histidine-rich protein II causes vascular leakage and exacerbates experimental cerebral malaria in mice.

Pal P, Balaban AE, Diamond MS, Sinnis P, Klein RS, Goldberg DE.

PLoS One. 2017 May 5;12(5):e0177142. doi: 10.1371/journal.pone.0177142. eCollection 2017.

47.

Vaccination strategies against Zika virus.

Fernandez E, Diamond MS.

Curr Opin Virol. 2017 Apr;23:59-67. doi: 10.1016/j.coviro.2017.03.006. Epub 2017 Apr 19. Review.

48.

TAM Receptors Are Not Required for Zika Virus Infection in Mice.

Hastings AK, Yockey LJ, Jagger BW, Hwang J, Uraki R, Gaitsch HF, Parnell LA, Cao B, Mysorekar IU, Rothlin CV, Fikrig E, Diamond MS, Iwasaki A.

Cell Rep. 2017 Apr 18;19(3):558-568. doi: 10.1016/j.celrep.2017.03.058.

49.

Maternal-Fetal Transmission of Zika Virus: Routes and Signals for Infection.

Cao B, Diamond MS, Mysorekar IU.

J Interferon Cytokine Res. 2017 Jul;37(7):287-294. doi: 10.1089/jir.2017.0011. Epub 2017 Apr 12. Review.

50.

Modified mRNA Vaccines Protect against Zika Virus Infection.

Richner JM, Himansu S, Dowd KA, Butler SL, Salazar V, Fox JM, Julander JG, Tang WW, Shresta S, Pierson TC, Ciaramella G, Diamond MS.

Cell. 2017 Mar 23;169(1):176. doi: 10.1016/j.cell.2017.03.016. No abstract available.

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