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Items: 1 to 50 of 96

1.

Specific Residues in a Purine Transporter Are Critical for Dimerization, ER Exit, and Function.

Kourkoulou A, Grevias P, Lambrinidis G, Pyle E, Dionysopoulou M, Politis A, Mikros E, Byrne B, Diallinas G.

Genetics. 2019 Dec;213(4):1357-1372. doi: 10.1534/genetics.119.302566. Epub 2019 Oct 14.

2.

Transporter membrane traffic and function: lessons from a mould.

Diallinas G, Martzoukou O.

FEBS J. 2019 Oct 4. doi: 10.1111/febs.15078. [Epub ahead of print] Review.

PMID:
31583839
3.

The peroxisomal SspA protein is redundant for purine utilization but essential for peroxisome localization in septal pores in Aspergillus nidulans.

Dimou S, Kourkoulou A, Amillis S, Percudani R, Diallinas G.

Fungal Genet Biol. 2019 Nov;132:103259. doi: 10.1016/j.fgb.2019.103259. Epub 2019 Aug 5.

PMID:
31394175
4.

Cytosolic N- and C-Termini of the Aspergillus nidulans FurE Transporter Contain Distinct Elements that Regulate by Long-Range Effects Function and Specificity.

Papadaki GF, Lambrinidis G, Zamanos A, Mikros E, Diallinas G.

J Mol Biol. 2019 Sep 6;431(19):3827-3844. doi: 10.1016/j.jmb.2019.07.013. Epub 2019 Jul 12.

PMID:
31306663
5.

Tales of tails in transporters.

Mikros E, Diallinas G.

Open Biol. 2019 Jun 28;9(6):190083. doi: 10.1098/rsob.190083. Epub 2019 Jun 19.

6.

Hydroxytyrosol (HT) Analogs Act as Potent Antifungals by Direct Disruption of the Fungal Cell Membrane.

Diallinas G, Rafailidou N, Kalpaktsi I, Komianou AC, Tsouvali V, Zantza I, Mikros E, Skaltsounis AL, Kostakis IK.

Front Microbiol. 2018 Nov 6;9:2624. doi: 10.3389/fmicb.2018.02624. eCollection 2018.

7.

The acetate uptake transporter family motif "NPAPLGL(M/S)" is essential for substrate uptake.

Ribas D, Soares-Silva I, Vieira D, Sousa-Silva M, Sá-Pessoa J, Azevedo-Silva J, Viegas SC, Arraiano CM, Diallinas G, Paiva S, Soares P, Casal M.

Fungal Genet Biol. 2019 Jan;122:1-10. doi: 10.1016/j.fgb.2018.10.001. Epub 2018 Oct 16.

PMID:
30339831
8.

Structure-activity relationships in fungal nucleobases transporters as dissected by the inhibitory effects of novel purine analogues.

Gavriil ES, Dimitrakis S, Papadaki G, Balaska S, Lambrinidis G, Lougiakis N, Marakos P, Diallinas G, Pouli N, Mikros E.

Eur J Med Chem. 2018 Aug 5;156:240-251. doi: 10.1016/j.ejmech.2018.06.038. Epub 2018 Jun 18.

PMID:
30006169
9.

Secretory Vesicle Polar Sorting, Endosome Recycling and Cytoskeleton Organization Require the AP-1 Complex in Aspergillus nidulans.

Martzoukou O, Diallinas G, Amillis S.

Genetics. 2018 Aug;209(4):1121-1138. doi: 10.1534/genetics.118.301240. Epub 2018 Jun 20.

10.

Evolution of substrate specificity in the Nucleobase-Ascorbate Transporter (NAT) protein family.

Kourkoulou A, Pittis AA, Diallinas G.

Microb Cell. 2018 Mar 22;5(6):280-292. doi: 10.15698/mic2018.06.636.

11.

Structural Lipids Enable the Formation of Functional Oligomers of the Eukaryotic Purine Symporter UapA.

Pyle E, Kalli AC, Amillis S, Hall Z, Lau AM, Hanyaloglu AC, Diallinas G, Byrne B, Politis A.

Cell Chem Biol. 2018 Jul 19;25(7):840-848.e4. doi: 10.1016/j.chembiol.2018.03.011. Epub 2018 Apr 19.

12.

Multiple nucleobase transporters contribute to boscalid sensitivity in Aspergillus nidulans.

Kalampokis IF, Kapetanakis GC, Aliferis KA, Diallinas G.

Fungal Genet Biol. 2018 Jun;115:52-63. doi: 10.1016/j.fgb.2018.02.004. Epub 2018 Mar 1.

PMID:
29501616
13.

Substrate Specificity of the FurE Transporter Is Determined by Cytoplasmic Terminal Domain Interactions.

Papadaki GF, Amillis S, Diallinas G.

Genetics. 2017 Dec;207(4):1387-1400. doi: 10.1534/genetics.117.300327. Epub 2017 Oct 4.

14.

The α-Arrestin Bul1p Mediates Lactate Transporter Endocytosis in Response to Alkalinization and Distinct Physiological Signals.

Talaia G, Gournas C, Saliba E, Barata-Antunes C, Casal M, André B, Diallinas G, Paiva S.

J Mol Biol. 2017 Nov 24;429(23):3678-3695. doi: 10.1016/j.jmb.2017.09.014. Epub 2017 Sep 28.

PMID:
28965784
15.

NmeA, a novel efflux transporter specific for nucleobases and nucleosides, contributes to metal resistance in Aspergillus nidulans.

Balaska S, Myrianthopoulos V, Tselika M, Hatzinikolaou DG, Mikros E, Diallinas G.

Mol Microbiol. 2017 Aug;105(3):426-439. doi: 10.1111/mmi.13708. Epub 2017 May 30.

16.

Transceptors as a functional link of transporters and receptors.

Diallinas G.

Microb Cell. 2017 Mar 1;4(3):69-73. doi: 10.15698/mic2017.03.560.

17.

Neuronal function of the mRNA decapping complex determines survival of Caenorhabditis elegans at high temperature through temporal regulation of heterochronic gene expression.

Borbolis F, Flessa CM, Roumelioti F, Diallinas G, Stravopodis DJ, Syntichaki P.

Open Biol. 2017 Mar;7(3). pii: 160313. doi: 10.1098/rsob.160313.

18.

The AP-2 complex has a specialized clathrin-independent role in apical endocytosis and polar growth in fungi.

Martzoukou O, Amillis S, Zervakou A, Christoforidis S, Diallinas G.

Elife. 2017 Feb 21;6. pii: e20083. doi: 10.7554/eLife.20083.

19.

Comparative genomics reveals high biological diversity and specific adaptations in the industrially and medically important fungal genus Aspergillus.

de Vries RP, Riley R, Wiebenga A, Aguilar-Osorio G, Amillis S, Uchima CA, Anderluh G, Asadollahi M, Askin M, Barry K, Battaglia E, Bayram Ö, Benocci T, Braus-Stromeyer SA, Caldana C, Cánovas D, Cerqueira GC, Chen F, Chen W, Choi C, Clum A, Dos Santos RA, Damásio AR, Diallinas G, Emri T, Fekete E, Flipphi M, Freyberg S, Gallo A, Gournas C, Habgood R, Hainaut M, Harispe ML, Henrissat B, Hildén KS, Hope R, Hossain A, Karabika E, Karaffa L, Karányi Z, Kraševec N, Kuo A, Kusch H, LaButti K, Lagendijk EL, Lapidus A, Levasseur A, Lindquist E, Lipzen A, Logrieco AF, MacCabe A, Mäkelä MR, Malavazi I, Melin P, Meyer V, Mielnichuk N, Miskei M, Molnár ÁP, Mulé G, Ngan CY, Orejas M, Orosz E, Ouedraogo JP, Overkamp KM, Park HS, Perrone G, Piumi F, Punt PJ, Ram AF, Ramón A, Rauscher S, Record E, Riaño-Pachón DM, Robert V, Röhrig J, Ruller R, Salamov A, Salih NS, Samson RA, Sándor E, Sanguinetti M, Schütze T, Sepčić K, Shelest E, Sherlock G, Sophianopoulou V, Squina FM, Sun H, Susca A, Todd RB, Tsang A, Unkles SE, van de Wiele N, van Rossen-Uffink D, Oliveira JV, Vesth TC, Visser J, Yu JH, Zhou M, Andersen MR, Archer DB, Baker SE, Benoit I, Brakhage AA, Braus GH, Fischer R, Frisvad JC, Goldman GH, Houbraken J, Oakley B, Pócsi I, Scazzocchio C, Seiboth B, vanKuyk PA, Wortman J, Dyer PS, Grigoriev IV.

Genome Biol. 2017 Feb 14;18(1):28. doi: 10.1186/s13059-017-1151-0.

20.

Transporter oligomerization: form and function.

Alguel Y, Cameron AD, Diallinas G, Byrne B.

Biochem Soc Trans. 2016 Dec 15;44(6):1737-1744. Review.

21.

Design and synthesis of purine analogues as highly specific ligands for FcyB, a ubiquitous fungal nucleobase transporter.

Lougiakis N, Gavriil ES, Kairis M, Sioupouli G, Lambrinidis G, Benaki D, Krypotou E, Mikros E, Marakos P, Pouli N, Diallinas G.

Bioorg Med Chem. 2016 Nov 15;24(22):5941-5952. doi: 10.1016/j.bmc.2016.09.055. Epub 2016 Sep 22.

PMID:
27720327
22.

Cryptic purine transporters in Aspergillus nidulans reveal the role of specific residues in the evolution of specificity in the NCS1 family.

Sioupouli G, Lambrinidis G, Mikros E, Amillis S, Diallinas G.

Mol Microbiol. 2017 Jan;103(2):319-332. doi: 10.1111/mmi.13559. Epub 2016 Nov 25.

23.

Dissection of Transporter Function: From Genetics to Structure.

Diallinas G.

Trends Genet. 2016 Sep;32(9):576-590. doi: 10.1016/j.tig.2016.06.003. Epub 2016 Jul 15. Review.

PMID:
27430403
24.

Structure of eukaryotic purine/H(+) symporter UapA suggests a role for homodimerization in transport activity.

Alguel Y, Amillis S, Leung J, Lambrinidis G, Capaldi S, Scull NJ, Craven G, Iwata S, Armstrong A, Mikros E, Diallinas G, Cameron AD, Byrne B.

Nat Commun. 2016 Apr 18;7:11336. doi: 10.1038/ncomms11336.

25.

BsdA(Bsd2) -dependent vacuolar turnover of a misfolded version of the UapA transporter along the secretory pathway: prominent role of selective autophagy.

Evangelinos M, Martzoukou O, Chorozian K, Amillis S, Diallinas G.

Mol Microbiol. 2016 Jun;100(5):893-911. doi: 10.1111/mmi.13358. Epub 2016 Mar 28.

26.

Oligomerization of the UapA Purine Transporter Is Critical for ER-Exit, Plasma Membrane Localization and Turnover.

Martzoukou O, Karachaliou M, Yalelis V, Leung J, Byrne B, Amillis S, Diallinas G.

J Mol Biol. 2015 Aug 14;427(16):2679-96. doi: 10.1016/j.jmb.2015.05.021. Epub 2015 Jun 3.

27.

Minos as a novel Tc1/mariner-type transposable element for functional genomic analysis in Aspergillus nidulans.

Evangelinos M, Anagnostopoulos G, Karvela-Kalogeraki I, Stathopoulou PM, Scazzocchio C, Diallinas G.

Fungal Genet Biol. 2015 Aug;81:1-11. doi: 10.1016/j.fgb.2015.05.007. Epub 2015 May 25.

PMID:
26021704
28.

Sul1 and Sul2 sulfate transceptors signal to protein kinase A upon exit of sulfur starvation.

Kankipati HN, Rubio-Texeira M, Castermans D, Diallinas G, Thevelein JM.

J Biol Chem. 2015 Apr 17;290(16):10430-46. doi: 10.1074/jbc.M114.629022. Epub 2015 Feb 27.

29.

Origin, diversification and substrate specificity in the family of NCS1/FUR transporters.

Krypotou E, Evangelidis T, Bobonis J, Pittis AA, Gabaldón T, Scazzocchio C, Mikros E, Diallinas G.

Mol Microbiol. 2015 Jun;96(5):927-50. doi: 10.1111/mmi.12982. Epub 2015 Apr 7.

30.

Expression and specificity profile of the major acetate transporter AcpA in Aspergillus nidulans.

Sá-Pessoa J, Amillis S, Casal M, Diallinas G.

Fungal Genet Biol. 2015 Mar;76:93-103. doi: 10.1016/j.fgb.2015.02.010. Epub 2015 Feb 21.

PMID:
25708319
31.

Functional characterization of NAT/NCS2 proteins of Aspergillus brasiliensis reveals a genuine xanthine-uric acid transporter and an intrinsically misfolded polypeptide.

Krypotou E, Scazzocchio C, Diallinas G.

Fungal Genet Biol. 2015 Feb;75:56-63. doi: 10.1016/j.fgb.2015.01.009. Epub 2015 Jan 29.

PMID:
25639910
32.

Understanding transporter specificity and the discrete appearance of channel-like gating domains in transporters.

Diallinas G.

Front Pharmacol. 2014 Sep 12;5:207. doi: 10.3389/fphar.2014.00207. eCollection 2014. Review.

33.

Purine utilization proteins in the Eurotiales: cellular compartmentalization, phylogenetic conservation and divergence.

Galanopoulou K, Scazzocchio C, Galinou ME, Liu W, Borbolis F, Karachaliou M, Oestreicher N, Hatzinikolaou DG, Diallinas G, Amillis S.

Fungal Genet Biol. 2014 Aug;69:96-108. doi: 10.1016/j.fgb.2014.06.005. Epub 2014 Jun 24.

PMID:
24970358
34.

Modelling, substrate docking and mutational analysis identify residues essential for function and specificity of the major fungal purine transporter AzgA.

Krypotou E, Lambrinidis G, Evangelidis T, Mikros E, Diallinas G.

Mol Microbiol. 2014 Jul;93(1):129-45. doi: 10.1111/mmi.12646. Epub 2014 May 23.

35.

Transport assays in filamentous fungi: kinetic characterization of the UapC purine transporter of Aspergillus nidulans.

Krypotou E, Diallinas G.

Fungal Genet Biol. 2014 Feb;63:1-8. doi: 10.1016/j.fgb.2013.12.004. Epub 2013 Dec 16.

PMID:
24355588
36.

Allopurinol and xanthine use different translocation mechanisms and trajectories in the fungal UapA transporter.

Diallinas G.

Biochimie. 2013 Sep;95(9):1755-64. doi: 10.1016/j.biochi.2013.05.013. Epub 2013 Jun 18.

PMID:
23791789
37.

The arrestin-like protein ArtA is essential for ubiquitination and endocytosis of the UapA transporter in response to both broad-range and specific signals.

Karachaliou M, Amillis S, Evangelinos M, Kokotos AC, Yalelis V, Diallinas G.

Mol Microbiol. 2013 Apr;88(2):301-17. doi: 10.1111/mmi.12184. Epub 2013 Mar 12.

38.

Modeling, substrate docking, and mutational analysis identify residues essential for the function and specificity of a eukaryotic purine-cytosine NCS1 transporter.

Krypotou E, Kosti V, Amillis S, Myrianthopoulos V, Mikros E, Diallinas G.

J Biol Chem. 2012 Oct 26;287(44):36792-803. doi: 10.1074/jbc.M112.400382. Epub 2012 Sep 11.

39.

Identification of the substrate recognition and transport pathway in a eukaryotic member of the nucleobase-ascorbate transporter (NAT) family.

Kosti V, Lambrinidis G, Myrianthopoulos V, Diallinas G, Mikros E.

PLoS One. 2012;7(7):e41939. doi: 10.1371/journal.pone.0041939. Epub 2012 Jul 25.

40.

Stabilizing the heterologously expressed uric acid-xanthine transporter UapA from the lower eukaryote Aspergillus nidulans.

Leung J, Cameron AD, Diallinas G, Byrne B.

Mol Membr Biol. 2013 Feb;30(1):32-42. doi: 10.3109/09687688.2012.690572. Epub 2012 Jun 14.

PMID:
22694048
41.

The role of flotillin FloA and stomatin StoA in the maintenance of apical sterol-rich membrane domains and polarity in the filamentous fungus Aspergillus nidulans.

Takeshita N, Diallinas G, Fischer R.

Mol Microbiol. 2012 Mar;83(6):1136-52. doi: 10.1111/j.1365-2958.2012.07996.x. Epub 2012 Feb 14.

42.

Mutational analysis and modeling reveal functionally critical residues in transmembrane segments 1 and 3 of the UapA transporter.

Amillis S, Kosti V, Pantazopoulou A, Mikros E, Diallinas G.

J Mol Biol. 2011 Aug 19;411(3):567-80. doi: 10.1016/j.jmb.2011.06.024. Epub 2011 Jun 29.

PMID:
21722649
43.

A substrate translocation trajectory in a cytoplasm-facing topological model of the monocarboxylate/H⁺ symporter Jen1p.

Soares-Silva I, Sá-Pessoa J, Myrianthopoulos V, Mikros E, Casal M, Diallinas G.

Mol Microbiol. 2011 Aug;81(3):805-17. doi: 10.1111/j.1365-2958.2011.07729.x. Epub 2011 Jun 28.

44.

Completing the purine utilisation pathway of Aspergillus nidulans.

Gournas C, Oestreicher N, Amillis S, Diallinas G, Scazzocchio C.

Fungal Genet Biol. 2011 Aug;48(8):840-8. doi: 10.1016/j.fgb.2011.03.004. Epub 2011 Mar 16.

PMID:
21419234
45.

Homologous overexpression of xylanase in Fusarium oxysporum increases ethanol productivity during consolidated bioprocessing (CBP) of lignocellulosics.

Anasontzis GE, Zerva A, Stathopoulou PM, Haralampidis K, Diallinas G, Karagouni AD, Hatzinikolaou DG.

J Biotechnol. 2011 Mar 10;152(1-2):16-23. doi: 10.1016/j.jbiotec.2011.01.002. Epub 2011 Jan 13.

PMID:
21237221
46.

A bacteria-specific 2[4Fe-4S] ferredoxin is essential in Pseudomonas aeruginosa.

Elsen S, Efthymiou G, Peteinatos P, Diallinas G, Kyritsis P, Moulis JM.

BMC Microbiol. 2010 Oct 28;10:271. doi: 10.1186/1471-2180-10-271.

47.

Hypertonic conditions trigger transient plasmolysis, growth arrest and blockage of transporter endocytosis in Aspergillus nidulans and Saccharomyces cerevisiae.

Bitsikas V, Karachaliou M, Gournas C, Diallinas G.

Mol Membr Biol. 2011 Jan;28(1):54-68. doi: 10.3109/09687688.2010.510484. Epub 2010 Oct 4.

PMID:
20919858
48.

Dynamic elements at both cytoplasmically and extracellularly facing sides of the UapA transporter selectively control the accessibility of substrates to their translocation pathway.

Kosti V, Papageorgiou I, Diallinas G.

J Mol Biol. 2010 Apr 16;397(5):1132-43. doi: 10.1016/j.jmb.2010.02.037. Epub 2010 Feb 25.

PMID:
20188741
49.

Expression and purification of a functional uric acid-xanthine transporter (UapA).

Leung J, Karachaliou M, Alves C, Diallinas G, Byrne B.

Protein Expr Purif. 2010 Jul;72(1):139-46. doi: 10.1016/j.pep.2010.02.002. Epub 2010 Feb 11.

PMID:
20153431
50.

Transporters, channels, or simple diffusion? Dogmas, atypical roles and complexity in transport systems.

Conde A, Diallinas G, Chaumont F, Chaves M, Gerós H.

Int J Biochem Cell Biol. 2010 Jun;42(6):857-68. doi: 10.1016/j.biocel.2009.12.012. Epub 2009 Dec 22. Review.

PMID:
20026419

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