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Items: 1 to 50 of 56

1.

Chemoprevention with phosphatidylcholine non-steroidal anti-inflammatory drugs in vivo and in vitro.

Lichtenberger LM, Phan T, Fang D, Dial EJ.

Oncol Lett. 2018 May;15(5):6688-6694. doi: 10.3892/ol.2018.8098. Epub 2018 Feb 21.

2.
3.

Unlocking Aspirin's Chemopreventive Activity: Role of Irreversibly Inhibiting Platelet Cyclooxygenase-1.

Lichtenberger LM, Fang D, Bick RJ, Poindexter BJ, Phan T, Bergeron AL, Pradhan S, Dial EJ, Vijayan KV.

Cancer Prev Res (Phila). 2017 Feb;10(2):142-152. doi: 10.1158/1940-6207.CAPR-16-0241. Epub 2016 Dec 20.

4.

Antitumor and Antiangiogenic Effects of Aspirin-PC in Ovarian Cancer.

Huang Y, Lichtenberger LM, Taylor M, Bottsford-Miller JN, Haemmerle M, Wagner MJ, Lyons Y, Pradeep S, Hu W, Previs RA, Hansen JM, Fang D, Dorniak PL, Filant J, Dial EJ, Shen F, Hatakeyama H, Sood AK.

Mol Cancer Ther. 2016 Dec;15(12):2894-2904. Epub 2016 Sep 16.

5.

Indomethacin injury to the rat small intestine is dependent upon biliary secretion and is associated with overgrowth of enterococci.

Mayo SA, Song YK, Cruz MR, Phan TM, Singh KV, Garsin DA, Murray BE, Dial EJ, Lichtenberger LM.

Physiol Rep. 2016 Mar;4(6). pii: e12725. doi: 10.14814/phy2.12725. Epub 2016 Mar 31.

6.

Suppression of contractile activity in the small intestine by indomethacin and omeprazole.

Lichtenberger LM, Bhattarai D, Phan TM, Dial EJ, Uray K.

Am J Physiol Gastrointest Liver Physiol. 2015 May 1;308(9):G785-93. doi: 10.1152/ajpgi.00458.2014. Epub 2015 Feb 26.

7.

In vitro evidence that phosphatidylcholine protects against indomethacin/bile acid-induced injury to cells.

Dial EJ, Dawson PA, Lichtenberger LM.

Am J Physiol Gastrointest Liver Physiol. 2015 Feb 1;308(3):G217-22. doi: 10.1152/ajpgi.00322.2014. Epub 2014 Dec 4.

8.

Bile acids modulate signaling by functional perturbation of plasma membrane domains.

Zhou Y, Maxwell KN, Sezgin E, Lu M, Liang H, Hancock JF, Dial EJ, Lichtenberger LM, Levental I.

J Biol Chem. 2013 Dec 13;288(50):35660-70. doi: 10.1074/jbc.M113.519116. Epub 2013 Oct 28.

9.

Advent of novel phosphatidylcholine-associated nonsteroidal anti-inflammatory drugs with improved gastrointestinal safety.

Lim YJ, Dial EJ, Lichtenberger LM.

Gut Liver. 2013 Jan;7(1):7-15. doi: 10.5009/gnl.2013.7.1.7. Epub 2012 Nov 13.

10.

Endotoxin-induced changes in phospholipid dynamics of the stomach.

Dial EJ, Tran DM, Hyman A, Lichtenberger LM.

J Surg Res. 2013 Mar;180(1):140-6. doi: 10.1016/j.jss.2012.10.045. Epub 2012 Nov 9.

11.

In vitro and in vivo protection against indomethacin-induced small intestinal injury by proton pump inhibitors, acid pump antagonists, or indomethacin-phosphatidylcholine.

Lim YJ, Phan TM, Dial EJ, Graham DY, Lichtenberger LM.

Digestion. 2012;86(2):171-7. doi: 10.1159/000339882. Epub 2012 Aug 14.

12.

Insight into NSAID-induced membrane alterations, pathogenesis and therapeutics: characterization of interaction of NSAIDs with phosphatidylcholine.

Lichtenberger LM, Zhou Y, Jayaraman V, Doyen JR, O'Neil RG, Dial EJ, Volk DE, Gorenstein DG, Boggara MB, Krishnamoorti R.

Biochim Biophys Acta. 2012 Jul;1821(7):994-1002. doi: 10.1016/j.bbalip.2012.04.002. Epub 2012 Apr 14.

13.

Bile acids improve the antimicrobial effect of rifaximin.

Darkoh C, Lichtenberger LM, Ajami N, Dial EJ, Jiang ZD, DuPont HL.

Antimicrob Agents Chemother. 2010 Sep;54(9):3618-24. doi: 10.1128/AAC.00161-10. Epub 2010 Jun 14.

14.

Effect of indomethacin on bile acid-phospholipid interactions: implication for small intestinal injury induced by nonsteroidal anti-inflammatory drugs.

Zhou Y, Dial EJ, Doyen R, Lichtenberger LM.

Am J Physiol Gastrointest Liver Physiol. 2010 May;298(5):G722-31. doi: 10.1152/ajpgi.00387.2009. Epub 2010 Mar 4.

15.

A direct role for secretory phospholipase A2 and lysophosphatidylcholine in the mediation of LPS-induced gastric injury.

Dial EJ, Tran DM, Romero JJ, Zayat M, Lichtenberger LM.

Shock. 2010 Jun;33(6):634-8. doi: 10.1097/SHK.0b013e3181cb9266.

16.

Gastrointestinal safety and therapeutic efficacy of parenterally administered phosphatidylcholine-associated indomethacin in rodent model systems.

Lichtenberger L, Romero JJ, Dial EJ.

Br J Pharmacol. 2009 May;157(2):252-7. doi: 10.1111/j.1476-5381.2009.00159.x. Epub 2009 Apr 20.

17.

Naproxen-PC: a GI safe and highly effective anti-inflammatory.

Lichtenberger LM, Romero JJ, Dial EJ, Moore JE.

Inflammopharmacology. 2009 Feb;17(1):1-5. doi: 10.1007/s10787-008-8047-2.

PMID:
19139828
18.

Oral phosphatidylcholine preserves the gastrointestinal mucosal barrier during LPS-induced inflammation.

Dial EJ, Zayat M, Lopez-Storey M, Tran D, Lichtenberger L.

Shock. 2008 Dec;30(6):729-33. doi: 10.1097/SHK.0b013e318173e8d4.

PMID:
18496240
19.

Pathophysiology of LPS-induced gastrointestinal injury in the rat: role of secretory phospholipase A2.

Zayat M, Lichtenberger LM, Dial EJ.

Shock. 2008 Aug;30(2):206-11. doi: 10.1097/shk.0b013e318160f47f.

PMID:
18180698
20.

Importance of biliary excretion of indomethacin in gastrointestinal and hepatic injury.

Dial EJ, Darling RL, Lichtenberger LM.

J Gastroenterol Hepatol. 2008 Aug;23(8 Pt 2):e384-9. Epub 2007 Dec 13.

PMID:
18086111
21.

Role of phosphatidylcholine saturation in preventing bile salt toxicity to gastrointestinal epithelia and membranes.

Dial EJ, Rooijakkers SH, Darling RL, Romero JJ, Lichtenberger LM.

J Gastroenterol Hepatol. 2008 Mar;23(3):430-6. Epub 2007 Sep 12.

PMID:
17868333
22.
24.

Phosphatidylcholine-associated nonsteroidal anti-inflammatory drugs (NSAIDs) inhibit DNA synthesis and the growth of colon cancer cells in vitro.

Dial EJ, Doyen JR, Lichtenberger LM.

Cancer Chemother Pharmacol. 2006 Feb;57(3):295-300. Epub 2005 Jul 20.

PMID:
16032431
25.

Recombinant human lactoferrin prevents NSAID-induced intestinal bleeding in rodents.

Dial EJ, Dohrman AJ, Romero JJ, Lichtenberger LM.

J Pharm Pharmacol. 2005 Jan;57(1):93-9.

PMID:
15651117
26.

The effects of aspirin on gastric mucosal integrity, surface hydrophobicity, and prostaglandin metabolism in cyclooxygenase knockout mice.

Darling RL, Romero JJ, Dial EJ, Akunda JK, Langenbach R, Lichtenberger LM.

Gastroenterology. 2004 Jul;127(1):94-104.

PMID:
15236176
27.

Effect of lactoferrin on Helicobacter felis induced gastritis.

Dial EJ, Lichtenberger LM.

Biochem Cell Biol. 2002;80(1):113-7. Review.

PMID:
11908634
28.

Lipopolysaccharide-induced gastrointestinal injury in rats: role of surface hydrophobicity and bile salts.

Dial EJ, Romero JJ, Villa X, Mercer DW, Lichtenberger LM.

Shock. 2002 Jan;17(1):77-80.

PMID:
11795673
29.

Recombinant human lactoferrin is effective in the treatment of Helicobacter felis-infected mice.

Dial EJ, Romero JJ, Headon DR, Lichtenberger LM.

J Pharm Pharmacol. 2000 Dec;52(12):1541-6.

PMID:
11197084
30.

Altered gastrin regulation in mice infected with Helicobacter felis.

Dial EJ, Hall LR, Romero JJ, Lechago J, Fox JG, Lichtenberger LM.

Dig Dis Sci. 2000 Jul;45(7):1308-14.

PMID:
10961708
31.

Attenuation of hydrophobic phospholipid barrier is an early event in Helicobacter felis-induced gastritis in mice.

Lichtenberger LM, Dial EJ, Ottlecz A, Romero JJ, Lechago J, Fox JG.

Dig Dis Sci. 1999 Jan;44(1):108-15.

PMID:
9952231
32.

Antibiotic properties of bovine lactoferrin on Helicobacter pylori.

Dial EJ, Hall LR, Serna H, Romero JJ, Fox JG, Lichtenberger LM.

Dig Dis Sci. 1998 Dec;43(12):2750-6.

PMID:
9881510
33.

Effect of omeprazole on the bioavailability of unmodified and phospholipid-complexed aspirin in rats.

Giraud MN, Sanduja SK, Felder TB, Illich PA, Dial EJ, Lichtenberger LM.

Aliment Pharmacol Ther. 1997 Oct;11(5):899-906.

34.

Nonsteroidal anti-inflammatory drug and phospholipid prodrugs: combination therapy with antisecretory agents in rats.

Lichtenberger LM, Ulloa C, Romero JJ, Vanous AL, Illich PA, Dial EJ.

Gastroenterology. 1996 Oct;111(4):990-5.

PMID:
8831593
35.

Zwitterionic phospholipids enhance aspirin's therapeutic activity, as demonstrated in rodent model systems.

Lichtenberger LM, Ulloa C, Vanous AL, Romero JJ, Dial EJ, Illich PA, Walters ET.

J Pharmacol Exp Ther. 1996 Jun;277(3):1221-7.

PMID:
8667182
36.

Rats with gastritis have increased sensitivity to the gastrin stimulatory effects of luminal ammonia.

Dial EJ, Hall LR, Romero JJ, Lichtenberger LM.

Gastroenterology. 1996 Mar;110(3):801-8.

PMID:
8608890
37.

Gastroprotection by dairy foods against stress-induced ulcerogenesis in rats.

Dial EJ, Romero JJ, Lichtenberger LM.

Dig Dis Sci. 1995 Nov;40(11):2295-9.

PMID:
7587804
38.

Role of luminal ammonia in the development of gastropathy and hypergastrinemia in the rat.

Lichtenberger LM, Dial EJ, Romero JJ, Lechago J, Jarboe LA, Wolfe MM.

Gastroenterology. 1995 Feb;108(2):320-9.

PMID:
7835572
39.

Accumulation of aliphatic amines in gastric juice of acute renal failure patients. Possible cause of hypergastrinemia associated with uremia.

Lichtenberger LM, Gardner JW, Barreto JC, Dial EJ, Weinman EJ.

Dig Dis Sci. 1993 Oct;38(10):1885-8.

PMID:
8404409
40.

Use of fluorescent hydrophobic dyes in establishing the presence of lipids in the gastric mucus gel layer.

Lichtenberger LM, Ahmed TN, Barreto JC, Kao YC, Dial EJ.

J Clin Gastroenterol. 1992;14 Suppl 1:S82-7.

PMID:
1378468
41.

Amino acid- and amine-induced gastrin release from isolated rat endocrine granules.

Dial EJ, Cooper LC, Lichtenberger LM.

Am J Physiol. 1991 Feb;260(2 Pt 1):G175-81.

PMID:
1996637
42.
43.
44.

Gastric protective activity of mixtures of saturated polar and neutral lipids in rats.

Lichtenberger LM, Romero JJ, Kao YC, Dial EJ.

Gastroenterology. 1990 Aug;99(2):311-26.

PMID:
2365185
45.

Surface hydrophobicity and water transport of the toad urinary bladder: effects of vasopressin.

Dial EJ, Huang J, O'Neil RG, Hills BA, Lichtenberger LM.

J Membr Biol. 1988 Dec;106(2):119-22.

PMID:
3147334
46.
47.

Milk protection against experimental ulcerogenesis in rats.

Dial EJ, Lichtenberger LM.

Dig Dis Sci. 1987 Oct;32(10):1145-50.

PMID:
3652898
48.
49.

Monoamine oxidase: an important intracellular regulator of gastrin release in the rat.

Dial EJ, Huang J, Delansorne R, Lichtenberger LM.

Gastroenterology. 1986 Apr;90(4):1018-23.

PMID:
3081396
50.

A role for milk phospholipids in protection against gastric acid. Studies in adult and suckling rats.

Dial EJ, Lichtenberger LM.

Gastroenterology. 1984 Aug;87(2):379-85.

PMID:
6610595

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