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Items: 16


Pentoxifylline Alone or in Combination with Gentamicin or Vancomycin Inhibits Live Microbe-Induced Proinflammatory Cytokine Production in Human Cord Blood and Cord Blood Monocytes In Vitro.

Speer EM, Diago-Navarro E, Ozog LS, Dowling DJ, Hou W, Raheel M, Fries BC, Levy O.

Antimicrob Agents Chemother. 2018 Nov 26;62(12). pii: e01462-18. doi: 10.1128/AAC.01462-18. Print 2018 Dec.


Erratum for Diago-Navarro et al., "Novel, Broadly Reactive Anticapsular Antibodies against Carbapenem-Resistant Klebsiella pneumoniae Protect from Infection".

Diago-Navarro E, Motley MP, Ruiz-Peréz G, Yu W, Austin J, Seco BMS, Xiao G, Chikhalya A, Seeberger PH, Fries BC.

MBio. 2018 Jun 12;9(3). pii: e01005-18. doi: 10.1128/mBio.01005-18. No abstract available.


Novel, Broadly Reactive Anticapsular Antibodies against Carbapenem-Resistant Klebsiella pneumoniae Protect from Infection.

Diago-Navarro E, Motley MP, Ruiz-Peréz G, Yu W, Austin J, Seco BMS, Xiao G, Chikhalya A, Seeberger PH, Fries BC.

MBio. 2018 Apr 3;9(2). pii: e00091-18. doi: 10.1128/mBio.00091-18. Erratum in: MBio. 2018 Jun 12;9(3):.


A Semi-Synthetic Glycoconjugate Vaccine Candidate for Carbapenem-Resistant Klebsiella pneumoniae.

Seeberger PH, Pereira CL, Khan N, Xiao G, Diago-Navarro E, Reppe K, Opitz B, Fries BC, Witzenrath M.

Angew Chem Int Ed Engl. 2017 Nov 6;56(45):13973-13978. doi: 10.1002/anie.201700964. Epub 2017 Oct 5.


Generational distribution of a Candida glabrata population: Resilient old cells prevail, while younger cells dominate in the vulnerable host.

Bouklas T, Alonso-Crisóstomo L, Székely T Jr, Diago-Navarro E, Orner EP, Smith K, Munshi MA, Del Poeta M, Balázsi G, Fries BC.

PLoS Pathog. 2017 May 10;13(5):e1006355. doi: 10.1371/journal.ppat.1006355. eCollection 2017 May.


Antibody-Based Immunotherapy To Treat and Prevent Infection with Hypervirulent Klebsiella pneumoniae.

Diago-Navarro E, Calatayud-Baselga I, Sun D, Khairallah C, Mann I, Ulacia-Hernando A, Sheridan B, Shi M, Fries BC.

Clin Vaccine Immunol. 2017 Jan 5;24(1). pii: e00456-16. doi: 10.1128/CVI.00456-16. Print 2017 Jan.


Characterization of the virulence of Cryptococcus neoformans strains in an insect model.

Bouklas T, Diago-Navarro E, Wang X, Fenster M, Fries BC.

Virulence. 2015;6(8):809-13. doi: 10.1080/21505594.2015.1086868. Epub 2015 Sep 12. No abstract available.


Carbapenem-resistant Klebsiella pneumoniae exhibit variability in capsular polysaccharide and capsule associated virulence traits.

Diago-Navarro E, Chen L, Passet V, Burack S, Ulacia-Hernando A, Kodiyanplakkal RP, Levi MH, Brisse S, Kreiswirth BN, Fries BC.

J Infect Dis. 2014 Sep 1;210(5):803-13. doi: 10.1093/infdis/jiu157. Epub 2014 Mar 14.


Cleavage of the antitoxin of the parD toxin-antitoxin system is determined by the ClpAP protease and is modulated by the relative ratio of the toxin and the antitoxin.

Diago-Navarro E, Hernández-Arriaga AM, Kubik S, Konieczny I, Díaz-Orejas R.

Plasmid. 2013 Jul;70(1):78-85. doi: 10.1016/j.plasmid.2013.01.010. Epub 2013 Feb 15.


A common origin for the bacterial toxin-antitoxin systems parD and ccd, suggested by analyses of toxin/target and toxin/antitoxin interactions.

Smith AB, López-Villarejo J, Diago-Navarro E, Mitchenall LA, Barendregt A, Heck AJ, Lemonnier M, Maxwell A, Díaz-Orejas R.

PLoS One. 2012;7(9):e46499. doi: 10.1371/journal.pone.0046499. Epub 2012 Sep 28.


The toxin-antitoxin proteins relBE2Spn of Streptococcus pneumoniae: characterization and association to their DNA target.

Moreno-Córdoba I, Diago-Navarro E, Barendregt A, Heck AJ, Alfonso C, Díaz-Orejas R, Nieto C, Espinosa M.

Proteins. 2012 Jul;80(7):1834-46. doi: 10.1002/prot.24081. Epub 2012 May 8.


Kis antitoxin couples plasmid R1 replication and parD (kis,kid) maintenance modules.

López-Villarejo J, Diago-Navarro E, Hernández-Arriaga AM, Díaz-Orejas R.

Plasmid. 2012 Mar;67(2):118-27. doi: 10.1016/j.plasmid.2011.12.015. Epub 2012 Jan 8.


The ribonucleolytic activity of the ribotoxin α-sarcin is not essential for in vitro protein biosynthesis inhibition.

Alvarez-García E, Diago-Navarro E, Herrero-Galán E, García-Ortega L, López-Villarejo J, Olmo N, Díaz-Orejas R, Gavilanes JG, Martínez-del-Pozo A.

Biochim Biophys Acta. 2011 Oct;1814(10):1377-82. doi: 10.1016/j.bbapap.2011.06.017. Epub 2011 Jul 13.


parD toxin-antitoxin system of plasmid R1--basic contributions, biotechnological applications and relationships with closely-related toxin-antitoxin systems.

Diago-Navarro E, Hernandez-Arriaga AM, López-Villarejo J, Muñoz-Gómez AJ, Kamphuis MB, Boelens R, Lemonnier M, Díaz-Orejas R.

FEBS J. 2010 Aug;277(15):3097-117. doi: 10.1111/j.1742-4658.2010.07722.x. Epub 2010 Jun 21. Review.


A mutagenic analysis of the RNase mechanism of the bacterial Kid toxin by mass spectrometry.

Diago-Navarro E, Kamphuis MB, Boelens R, Barendregt A, Heck AJ, van den Heuvel RH, Díaz-Orejas R.

FEBS J. 2009 Sep;276(17):4973-86. doi: 10.1111/j.1742-4658.2009.07199.x. Epub 2009 Aug 4.


Novel Escherichia coli RF1 mutants with decreased translation termination activity and increased sensitivity to the cytotoxic effect of the bacterial toxins Kid and RelE.

Diago-Navarro E, Mora L, Buckingham RH, Díaz-Orejas R, Lemonnier M.

Mol Microbiol. 2009 Jan;71(1):66-78. doi: 10.1111/j.1365-2958.2008.06510.x. Epub 2008 Oct 28.

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