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Items: 30


miR-141-Mediated Regulation of Brain Metastasis From Breast Cancer.

Debeb BG, Lacerda L, Anfossi S, Diagaradjane P, Chu K, Bambhroliya A, Huo L, Wei C, Larson RA, Wolfe AR, Xu W, Smith DL, Li L, Ivan C, Allen PK, Wu W, Calin GA, Krishnamurthy S, Zhang XH, Buchholz TA, Ueno NT, Reuben JM, Woodward WA.

J Natl Cancer Inst. 2016 Apr 13;108(8). doi: 10.1093/jnci/djw026. Print 2016 Aug.


Quantitative imaging of gold nanoparticle distribution in a tumor-bearing mouse using benchtop x-ray fluorescence computed tomography.

Manohar N, Reynoso FJ, Diagaradjane P, Krishnan S, Cho SH.

Sci Rep. 2016 Feb 25;6:22079. doi: 10.1038/srep22079.


Zerumbone increases oxidative stress in a thiol-dependent ROS-independent manner to increase DNA damage and sensitize colorectal cancer cells to radiation.

Deorukhkar A, Ahuja N, Mercado AL, Diagaradjane P, Raju U, Patel N, Mohindra P, Diep N, Guha S, Krishnan S.

Cancer Med. 2015 Feb;4(2):278-92. doi: 10.1002/cam4.367. Epub 2014 Dec 1.


Convergence of nanotechnology with radiation therapy-insights and implications for clinical translation.

Chatterjee DK, Wolfe T, Lee J, Brown AP, Singh PK, Bhattarai SR, Diagaradjane P, Krishnan S.

Transl Cancer Res. 2013 Aug 23;2(4):256-268.


Ursolic acid inhibits growth and metastasis of human colorectal cancer in an orthotopic nude mouse model by targeting multiple cell signaling pathways: chemosensitization with capecitabine.

Prasad S, Yadav VR, Sung B, Reuter S, Kannappan R, Deorukhkar A, Diagaradjane P, Wei C, Baladandayuthapani V, Krishnan S, Guha S, Aggarwal BB.

Clin Cancer Res. 2012 Sep 15;18(18):4942-53. doi: 10.1158/1078-0432.CCR-11-2805. Epub 2012 Jul 25.


Nanoparticle-mediated hyperthermia in cancer therapy.

Chatterjee DK, Diagaradjane P, Krishnan S.

Ther Deliv. 2011 Aug;2(8):1001-14.


Narrow band imaging of squamous cell carcinoma tumors using topically delivered anti-EGFR antibody conjugated gold nanorods.

Puvanakrishnan P, Diagaradjane P, Kazmi SM, Dunn AK, Krishnan S, Tunnell JW.

Lasers Surg Med. 2012 Apr;44(4):310-7. doi: 10.1002/lsm.22019. Epub 2012 Mar 13.


Zyflamend suppresses growth and sensitizes human pancreatic tumors to gemcitabine in an orthotopic mouse model through modulation of multiple targets.

Kunnumakkara AB, Sung B, Ravindran J, Diagaradjane P, Deorukhkar A, Dey S, Koca C, Tong Z, Gelovani JG, Guha S, Krishnan S, Aggarwal BB.

Int J Cancer. 2012 Aug 1;131(3):E292-303. doi: 10.1002/ijc.26442. Epub 2011 Nov 9.


Integrin αvβ3-targeted gold nanoshells augment tumor vasculature-specific imaging and therapy.

Xie H, Diagaradjane P, Deorukhkar AA, Goins B, Bao A, Phillips WT, Wang Z, Schwartz J, Krishnan S.

Int J Nanomedicine. 2011;6:259-69. doi: 10.2147/IJN.S15479. Epub 2011 Jan 27.


Intra-organ Biodistribution of Gold Nanoparticles Using Intrinsic Two-photon Induced Photoluminescence.

Park J, Estrada A, Schwartz JA, Diagaradjane P, Krishnan S, Dunn AK, Tunnell JW.

Lasers Surg Med. 2010 Sep;42(7):630-639.


Thermal enhancement with optically activated gold nanoshells sensitizes breast cancer stem cells to radiation therapy.

Atkinson RL, Zhang M, Diagaradjane P, Peddibhotla S, Contreras A, Hilsenbeck SG, Woodward WA, Krishnan S, Chang JC, Rosen JM.

Sci Transl Med. 2010 Oct 27;2(55):55ra79. doi: 10.1126/scitranslmed.3001447.


{Gamma}-tocotrienol inhibits pancreatic tumors and sensitizes them to gemcitabine treatment by modulating the inflammatory microenvironment.

Kunnumakkara AB, Sung B, Ravindran J, Diagaradjane P, Deorukhkar A, Dey S, Koca C, Yadav VR, Tong Z, Gelovani JG, Guha S, Krishnan S, Aggarwal BB.

Cancer Res. 2010 Nov 1;70(21):8695-705. doi: 10.1158/0008-5472.CAN-10-2318. Epub 2010 Sep 23. Erratum in: Cancer Res. 2018 Sep 1;78(17):5181.


Nanoparticle-mediated thermal therapy: evolving strategies for prostate cancer therapy.

Krishnan S, Diagaradjane P, Cho SH.

Int J Hyperthermia. 2010;26(8):775-89. doi: 10.3109/02656736.2010.485593. Epub 2010 Sep 21. Review.


Gadolinium chloride augments tumor-specific imaging of targeted quantum dots in vivo.

Diagaradjane P, Deorukhkar A, Gelovani JG, Maru DM, Krishnan S.

ACS Nano. 2010 Jul 27;4(7):4131-41. doi: 10.1021/nn901919w.


Inhibition of radiation-induced DNA repair and prosurvival pathways contributes to vorinostat-mediated radiosensitization of pancreatic cancer cells.

Deorukhkar A, Shentu S, Park HC, Diagaradjane P, Puduvalli V, Aggarwal B, Guha S, Krishnan S.

Pancreas. 2010 Nov;39(8):1277-83. doi: 10.1097/MPA.0b013e3181dd63e1.


A novel small-molecule inhibitor of protein kinase D blocks pancreatic cancer growth in vitro and in vivo.

Harikumar KB, Kunnumakkara AB, Ochi N, Tong Z, Deorukhkar A, Sung B, Kelland L, Jamieson S, Sutherland R, Raynham T, Charles M, Bagherzadeh A, Foxton C, Boakes A, Farooq M, Maru D, Diagaradjane P, Matsuo Y, Sinnett-Smith J, Gelovani J, Krishnan S, Aggarwal BB, Rozengurt E, Ireson CR, Guha S.

Mol Cancer Ther. 2010 May;9(5):1136-46. doi: 10.1158/1535-7163.MCT-09-1145. Epub 2010 May 4. Erratum in: Mol Cancer Ther. 2010 Jul;9(7):2153. Bagherazadeh, Azadeh [corrected to Bagherzadeh, Azadeh].


Resveratrol, a multitargeted agent, can enhance antitumor activity of gemcitabine in vitro and in orthotopic mouse model of human pancreatic cancer.

Harikumar KB, Kunnumakkara AB, Sethi G, Diagaradjane P, Anand P, Pandey MK, Gelovani J, Krishnan S, Guha S, Aggarwal BB.

Int J Cancer. 2010 Jul 15;127(2):257-68. doi: 10.1002/ijc.25041. Erratum in: Int J Cancer. 2015 Dec 15;137(12):E21.


Curcumin sensitizes human colorectal cancer to capecitabine by modulation of cyclin D1, COX-2, MMP-9, VEGF and CXCR4 expression in an orthotopic mouse model.

Kunnumakkara AB, Diagaradjane P, Anand P, Harikumar KB, Deorukhkar A, Gelovani J, Guha S, Krishnan S, Aggarwal BB.

Int J Cancer. 2009 Nov 1;125(9):2187-97. doi: 10.1002/ijc.24593. Erratum in: Int J Cancer. 2010 Feb 1;126(3):799. Kuzhuvelil, Harikumar B [corrected to Harikumar, Kuzhuvelil B].


Near-infrared narrow-band imaging of gold/silica nanoshells in tumors.

Puvanakrishnan P, Park J, Diagaradjane P, Schwartz JA, Coleman CL, Gill-Sharp KL, Sang KL, Payne JD, Krishnan S, Tunnell JW.

J Biomed Opt. 2009 Mar-Apr;14(2):024044. doi: 10.1117/1.3120494.


Neutrophil gelatinase-associated lipocalin: a novel suppressor of invasion and angiogenesis in pancreatic cancer.

Tong Z, Kunnumakkara AB, Wang H, Matsuo Y, Diagaradjane P, Harikumar KB, Ramachandran V, Sung B, Chakraborty A, Bresalier RS, Logsdon C, Aggarwal BB, Krishnan S, Guha S.

Cancer Res. 2008 Aug 1;68(15):6100-8. doi: 10.1158/0008-5472.CAN-08-0540.


Therapeutic significance of elevated tissue transglutaminase expression in pancreatic cancer.

Verma A, Guha S, Diagaradjane P, Kunnumakkara AB, Sanguino AM, Lopez-Berestein G, Sood AK, Aggarwal BB, Krishnan S, Gelovani JG, Mehta K.

Clin Cancer Res. 2008 Apr 15;14(8):2476-83. doi: 10.1158/1078-0432.CCR-07-4529.


Modulation of in vivo tumor radiation response via gold nanoshell-mediated vascular-focused hyperthermia: characterizing an integrated antihypoxic and localized vascular disrupting targeting strategy.

Diagaradjane P, Shetty A, Wang JC, Elliott AM, Schwartz J, Shentu S, Park HC, Deorukhkar A, Stafford RJ, Cho SH, Tunnell JW, Hazle JD, Krishnan S.

Nano Lett. 2008 May;8(5):1492-500. doi: 10.1021/nl080496z. Epub 2008 Apr 16.


Curcumin sensitizes human colorectal cancer xenografts in nude mice to gamma-radiation by targeting nuclear factor-kappaB-regulated gene products.

Kunnumakkara AB, Diagaradjane P, Guha S, Deorukhkar A, Shentu S, Aggarwal BB, Krishnan S.

Clin Cancer Res. 2008 Apr 1;14(7):2128-36. doi: 10.1158/1078-0432.CCR-07-4722.


Imaging epidermal growth factor receptor expression in vivo: pharmacokinetic and biodistribution characterization of a bioconjugated quantum dot nanoprobe.

Diagaradjane P, Orenstein-Cardona JM, Colón-Casasnovas NE, Deorukhkar A, Shentu S, Kuno N, Schwartz DL, Gelovani JG, Krishnan S.

Clin Cancer Res. 2008 Feb 1;14(3):731-41. doi: 10.1158/1078-0432.CCR-07-1958.


Comparative study of cryogen spray cooling with R-134a and R-404a: implications for laser treatment of dark human skin.

Dai T, Yaseen MA, Diagaradjane P, Chang DW, Anvari B.

J Biomed Opt. 2006 Jul-Aug;11(4):041116.


Synchronous fluorescence spectroscopic characterization of DMBA-TPA-induced squamous cell carcinoma in mice.

Diagaradjane P, Yaseen MA, Yu J, Wong MS, Anvari B.

J Biomed Opt. 2006 Jan-Feb;11(1):014012.


Autofluorescence characterization for the early diagnosis of neoplastic changes in DMBA/TPA-induced mouse skin carcinogenesis.

Diagaradjane P, Yaseen MA, Yu J, Wong MS, Anvari B.

Lasers Surg Med. 2005 Dec;37(5):382-95.


Laser-induced thermal injury to dermal blood vessels: analysis of wavelength (585 nm vs. 595 nm), cryogen spray cooling, and wound healing effects.

Dai T, Diagaradjane P, Yaseen MA, Pikkula BM, Thomsen S, Anvari B.

Lasers Surg Med. 2005 Sep;37(3):210-8.


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