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Items: 41


Integrin Regulation of CAF Differentiation and Function.

DiPersio CM, Van De Water L.

Cancers (Basel). 2019 May 24;11(5). pii: E715. doi: 10.3390/cancers11050715. Review.


Keratinocyte Integrin α3β1 Promotes Secretion of IL-1α to Effect Paracrine Regulation of Fibroblast Gene Expression and Differentiation.

Zheng R, Longmate WM, DeFreest L, Varney S, Wu L, DiPersio CM, Van De Water L.

J Invest Dermatol. 2019 Sep;139(9):2029-2038.e3. doi: 10.1016/j.jid.2019.02.025. Epub 2019 Mar 13.


Beyond adhesion: emerging roles for integrins in control of the tumor microenvironment.

Longmate W, DiPersio CM.

F1000Res. 2017 Aug 31;6:1612. doi: 10.12688/f1000research.11877.1. eCollection 2017. Review.


Opposing Roles of Epidermal Integrins α3β1 and α9β1 in Regulation of mTLD/BMP-1-Mediated Laminin-γ2 Processing during Wound Healing.

Longmate WM, Lyons SP, DeFreest L, Van De Water L, DiPersio CM.

J Invest Dermatol. 2018 Feb;138(2):444-451. doi: 10.1016/j.jid.2017.09.004. Epub 2017 Sep 18.


An FAK-YAP-mTOR Signaling Axis Regulates Stem Cell-Based Tissue Renewal in Mice.

Hu JK, Du W, Shelton SJ, Oldham MC, DiPersio CM, Klein OD.

Cell Stem Cell. 2017 Jul 6;21(1):91-106.e6. doi: 10.1016/j.stem.2017.03.023. Epub 2017 Apr 27.


Suppression of integrin α3β1 by α9β1 in the epidermis controls the paracrine resolution of wound angiogenesis.

Longmate WM, Lyons SP, Chittur SV, Pumiglia KM, Van De Water L, DiPersio CM.

J Cell Biol. 2017 May 1;216(5):1473-1488. doi: 10.1083/jcb.201510042. Epub 2017 Apr 17.


Integrin-mediated regulation of epidermal wound functions.

DiPersio CM, Zheng R, Kenney J, Van De Water L.

Cell Tissue Res. 2016 Sep;365(3):467-82. doi: 10.1007/s00441-016-2446-2. Epub 2016 Jun 28. Review.


Integrin α3β1 signaling through MEK/ERK determines alternative polyadenylation of the MMP-9 mRNA transcript in immortalized mouse keratinocytes.

Missan DS, Mitchell K, Subbaram S, DiPersio CM.

PLoS One. 2015 Mar 9;10(3):e0119539. doi: 10.1371/journal.pone.0119539. eCollection 2015.


Expression of integrin α3β1 and cyclooxygenase-2 (COX2) are positively correlated in human breast cancer.

Aggarwal A, Al-Rohil RN, Batra A, Feustel PJ, Jones DM, DiPersio CM.

BMC Cancer. 2014 Jun 20;14:459. doi: 10.1186/1471-2407-14-459.


Regulation of fibulin-2 gene expression by integrin α3β1 contributes to the invasive phenotype of transformed keratinocytes.

Missan DS, Chittur SV, DiPersio CM.

J Invest Dermatol. 2014 Sep;134(9):2418-2427. doi: 10.1038/jid.2014.166. Epub 2014 Apr 2.


Integrin Regulation of Epidermal Functions in Wounds.

Longmate WM, Dipersio CM.

Adv Wound Care (New Rochelle). 2014 Mar 1;3(3):229-246. Review.


Integrin α3β1 controls mRNA splicing that determines Cox-2 mRNA stability in breast cancer cells.

Subbaram S, Lyons SP, Svenson KB, Hammond SL, McCabe LG, Chittur SV, DiPersio CM.

J Cell Sci. 2014 Mar 15;127(Pt 6):1179-89. doi: 10.1242/jcs.131227. Epub 2014 Jan 16.


Reduced fibulin-2 contributes to loss of basement membrane integrity and skin blistering in mice lacking integrin α3β1 in the epidermis.

Longmate WM, Monichan R, Chu ML, Tsuda T, Mahoney MG, DiPersio CM.

J Invest Dermatol. 2014 Jun;134(6):1609-1617. doi: 10.1038/jid.2014.10. Epub 2014 Jan 3.


Integrin α3β1 as a breast cancer target.

Subbaram S, Dipersio CM.

Expert Opin Ther Targets. 2011 Oct;15(10):1197-210. doi: 10.1517/14728222.2011.609557. Epub 2011 Aug 13. Review.


KLF8 promotes human breast cancer cell invasion and metastasis by transcriptional activation of MMP9.

Wang X, Lu H, Urvalek AM, Li T, Yu L, Lamar J, DiPersio CM, Feustel PJ, Zhao J.

Oncogene. 2011 Apr 21;30(16):1901-11. doi: 10.1038/onc.2010.563. Epub 2010 Dec 13.


Endothelial alpha3beta1-integrin represses pathological angiogenesis and sustains endothelial-VEGF.

da Silva RG, Tavora B, Robinson SD, Reynolds LE, Szekeres C, Lamar J, Batista S, Kostourou V, Germain MA, Reynolds AR, Jones DT, Watson AR, Jones JL, Harris A, Hart IR, Iruela-Arispe ML, Dipersio CM, Kreidberg JA, Hodivala-Dilke KM.

Am J Pathol. 2010 Sep;177(3):1534-48. doi: 10.2353/ajpath.2010.100043. Epub 2010 Jul 16.


Suppression of integrin alpha3beta1 in breast cancer cells reduces cyclooxygenase-2 gene expression and inhibits tumorigenesis, invasion, and cross-talk to endothelial cells.

Mitchell K, Svenson KB, Longmate WM, Gkirtzimanaki K, Sadej R, Wang X, Zhao J, Eliopoulos AG, Berditchevski F, Dipersio CM.

Cancer Res. 2010 Aug 1;70(15):6359-67. doi: 10.1158/0008-5472.CAN-09-4283. Epub 2010 Jul 14.


Determination of alternate splicing events using the Affymetrix Exon 1.0 ST arrays.

Subbaram S, Kuentzel M, Frank D, Dipersio CM, Chittur SV.

Methods Mol Biol. 2010;632:63-72. doi: 10.1007/978-1-60761-663-4_4.


Alpha3beta1 integrin in epidermis promotes wound angiogenesis and keratinocyte-to-endothelial-cell crosstalk through the induction of MRP3.

Mitchell K, Szekeres C, Milano V, Svenson KB, Nilsen-Hamilton M, Kreidberg JA, DiPersio CM.

J Cell Sci. 2009 Jun 1;122(Pt 11):1778-87. doi: 10.1242/jcs.040956. Epub 2009 May 12.


An immortalization-dependent switch in integrin function up-regulates MMP-9 to enhance tumor cell invasion.

Lamar JM, Pumiglia KM, DiPersio CM.

Cancer Res. 2008 Sep 15;68(18):7371-9. doi: 10.1158/0008-5472.CAN-08-1080.


alpha3beta1 integrin-controlled Smad7 regulates reepithelialization during wound healing in mice.

Reynolds LE, Conti FJ, Silva R, Robinson SD, Iyer V, Rudling R, Cross B, Nye E, Hart IR, Dipersio CM, Hodivala-Dilke KM.

J Clin Invest. 2008 Mar;118(3):965-74. doi: 10.1172/JCI33538.


Integrin alpha3beta1 potentiates TGFbeta-mediated induction of MMP-9 in immortalized keratinocytes.

Lamar JM, Iyer V, DiPersio CM.

J Invest Dermatol. 2008 Mar;128(3):575-86. Epub 2007 Aug 30.


Double duty for Rac1 in epidermal wound healing.

DiPersio CM.

Sci STKE. 2007 Jun 19;2007(391):pe33.


Integrin alpha3beta1-dependent activation of FAK/Src regulates Rac1-mediated keratinocyte polarization on laminin-5.

Choma DP, Milano V, Pumiglia KM, DiPersio CM.

J Invest Dermatol. 2007 Jan;127(1):31-40. Epub 2006 Aug 17.


Alpha 3 beta 1 integrin promotes keratinocyte cell survival through activation of a MEK/ERK signaling pathway.

Manohar A, Shome SG, Lamar J, Stirling L, Iyer V, Pumiglia K, DiPersio CM.

J Cell Sci. 2004 Aug 15;117(Pt 18):4043-54. Epub 2004 Jul 27.


Integrin alpha3beta1 directs the stabilization of a polarized lamellipodium in epithelial cells through activation of Rac1.

Choma DP, Pumiglia K, DiPersio CM.

J Cell Sci. 2004 Aug 1;117(Pt 17):3947-59. Epub 2004 Jul 20.


Tumor cell alpha3beta1 integrin and vascular laminin-5 mediate pulmonary arrest and metastasis.

Wang H, Fu W, Im JH, Zhou Z, Santoro SA, Iyer V, DiPersio CM, Yu QC, Quaranta V, Al-Mehdi A, Muschel RJ.

J Cell Biol. 2004 Mar 15;164(6):935-41.


Functional comparison of the alpha3A and alpha3B cytoplasmic domain variants of the chicken alpha3 integrin subunit.

DiPersio CM, Trevithick JE, Hynes RO.

Exp Cell Res. 2001 Aug 1;268(1):45-60.


alpha3beta1 and alpha6beta4 integrin receptors for laminin-5 are not essential for epidermal morphogenesis and homeostasis during skin development.

DiPersio CM, van der Neut R, Georges-Labouesse E, Kreidberg JA, Sonnenberg A, Hynes RO.

J Cell Sci. 2000 Sep;113 ( Pt 17):3051-62.


Mouse keratinocytes immortalized with large T antigen acquire alpha3beta1 integrin-dependent secretion of MMP-9/gelatinase B.

DiPersio CM, Shao M, Di Costanzo L, Kreidberg JA, Hynes RO.

J Cell Sci. 2000 Aug;113 ( Pt 16):2909-21.


alpha3beta1 Integrin is required for normal development of the epidermal basement membrane.

DiPersio CM, Hodivala-Dilke KM, Jaenisch R, Kreidberg JA, Hynes RO.

J Cell Biol. 1997 May 5;137(3):729-42.


Self-complementary oligopeptide matrices support mammalian cell attachment.

Zhang S, Holmes TC, DiPersio CM, Hynes RO, Su X, Rich A.

Biomaterials. 1995 Dec;16(18):1385-93.


Regulation of albumin gene expression in hepatoma cells of fetal phenotype: dominant inhibition of HNF1 function and role of ubiquitous transcription factors.

Rollier A, DiPersio CM, Cereghini S, Stevens K, Tronche F, Zaret K, Weiss MC.

Mol Biol Cell. 1993 Jan;4(1):59-69.


Conditional enhancement of liver-specific gene transcription.

Zaret KS, DiPersio CM, Jackson DA, Montigny WJ, Weinstat DL.

Proc Natl Acad Sci U S A. 1988 Dec;85(23):9076-80.

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