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Items: 1 to 50 of 204

1.

The Citrobacter rodentium type III secretion system effector EspO affects mucosal damage repair and antimicrobial responses.

Berger CN, Crepin VF, Roumeliotis TI, Wright JC, Serafini N, Pevsner-Fischer M, Yu L, Elinav E, Di Santo JP, Choudhary JS, Frankel G.

PLoS Pathog. 2018 Oct 26;14(10):e1007406. doi: 10.1371/journal.ppat.1007406. eCollection 2018 Oct.

2.

Peyer's patch myeloid cells infection by Listeria signals through gp38+ stromal cells and locks intestinal villus invasion.

Disson O, Blériot C, Jacob JM, Serafini N, Dulauroy S, Jouvion G, Fevre C, Gessain G, Thouvenot P, Eberl G, Di Santo JP, Peduto L, Lecuit M.

J Exp Med. 2018 Nov 5;215(11):2936-2954. doi: 10.1084/jem.20181210. Epub 2018 Oct 24.

PMID:
30355616
3.

ILC-poiesis: Ensuring tissue ILC differentiation at the right place and time.

Lim AI, Di Santo JP.

Eur J Immunol. 2018 Oct 23. doi: 10.1002/eji.201747294. [Epub ahead of print] Review.

PMID:
30350853
4.

Human thymopoiesis is influenced by a common genetic variant within the TCRA-TCRD locus.

Clave E, Araujo IL, Alanio C, Patin E, Bergstedt J, Urrutia A, Lopez-Lastra S, Li Y, Charbit B, MacPherson CR, Hasan M, Melo-Lima BL, Douay C, Saut N, Germain M, Trégouët DA, Morange PE, Fontes M, Duffy D, Di Santo JP, Quintana-Murci L, Albert ML, Toubert A; Milieu Intérieur Consortium.

Sci Transl Med. 2018 Sep 5;10(457). pii: eaao2966. doi: 10.1126/scitranslmed.aao2966.

PMID:
30185651
5.

Innate Lymphoid Cells: 10 Years On.

Vivier E, Artis D, Colonna M, Diefenbach A, Di Santo JP, Eberl G, Koyasu S, Locksley RM, McKenzie ANJ, Mebius RE, Powrie F, Spits H.

Cell. 2018 Aug 23;174(5):1054-1066. doi: 10.1016/j.cell.2018.07.017. Review.

PMID:
30142344
6.

A human immune system mouse model with robust lymph node development.

Li Y, Masse-Ranson G, Garcia Z, Bruel T, Kök A, Strick-Marchand H, Jouvion G, Serafini N, Lim AI, Dusseaux M, Hieu T, Bourgade F, Toubert A, Finke D, Schwartz O, Bousso P, Mouquet H, Di Santo JP.

Nat Methods. 2018 Aug;15(8):623-630. doi: 10.1038/s41592-018-0071-6. Epub 2018 Jul 31.

PMID:
30065364
7.

Innate Lymphoid Cell Development: A T Cell Perspective.

Cherrier DE, Serafini N, Di Santo JP.

Immunity. 2018 Jun 19;48(6):1091-1103. doi: 10.1016/j.immuni.2018.05.010. Review.

PMID:
29924975
8.

A recessive form of hyper-IgE syndrome by disruption of ZNF341-dependent STAT3 transcription and activity.

Béziat V, Li J, Lin JX, Ma CS, Li P, Bousfiha A, Pellier I, Zoghi S, Baris S, Keles S, Gray P, Du N, Wang Y, Zerbib Y, Lévy R, Leclercq T, About F, Lim AI, Rao G, Payne K, Pelham SJ, Avery DT, Deenick EK, Pillay B, Chou J, Guery R, Belkadi A, Guérin A, Migaud M, Rattina V, Ailal F, Benhsaien I, Bouaziz M, Habib T, Chaussabel D, Marr N, El-Benna J, Grimbacher B, Wargon O, Bustamante J, Boisson B, Müller-Fleckenstein I, Fleckenstein B, Chandesris MO, Titeux M, Fraitag S, Alyanakian MA, Leruez-Ville M, Picard C, Meyts I, Di Santo JP, Hovnanian A, Somer A, Ozen A, Rezaei N, Chatila TA, Abel L, Leonard WJ, Tangye SG, Puel A, Casanova JL.

Sci Immunol. 2018 Jun 15;3(24). pii: eaat4956. doi: 10.1126/sciimmunol.aat4956.

PMID:
29907691
9.

Publisher Correction: Natural variation in the parameters of innate immune cells is preferentially driven by genetic factors.

Patin E, Hasan M, Bergstedt J, Rouilly V, Libri V, Urrutia A, Alanio C, Scepanovic P, Hammer C, Jönsson F, Beitz B, Quach H, Lim YW, Hunkapiller J, Zepeda M, Green C, Piasecka B, Leloup C, Rogge L, Huetz F, Peguillet I, Lantz O, Fontes M, Di Santo JP, Thomas S, Fellay J, Duffy D, Quintana-Murci L, Albert ML; Milieu Intérieur Consortium.

Nat Immunol. 2018 Jun;19(6):645. doi: 10.1038/s41590-018-0105-3.

PMID:
29725081
10.

The Yin and Yang of regulatory T cells in immunotherapy.

Li Y, Di Santo JP.

Oncotarget. 2018 Feb 3;9(13):10828-10829. doi: 10.18632/oncotarget.24394. eCollection 2018 Feb 16. No abstract available.

11.

Epigenome analysis links gene regulatory elements in group 2 innate lymphocytes to asthma susceptibility.

Stadhouders R, Li BWS, de Bruijn MJW, Gomez A, Rao TN, Fehling HJ, van IJcken WFJ, Lim AI, Di Santo JP, Graf T, Hendriks RW.

J Allergy Clin Immunol. 2018 Dec;142(6):1793-1807. doi: 10.1016/j.jaci.2017.12.1006. Epub 2018 Mar 2.

PMID:
29486229
12.

Natural variation in the parameters of innate immune cells is preferentially driven by genetic factors.

Patin E, Hasan M, Bergstedt J, Rouilly V, Libri V, Urrutia A, Alanio C, Scepanovic P, Hammer C, Jönsson F, Beitz B, Quach H, Lim YW, Hunkapiller J, Zepeda M, Green C, Piasecka B, Leloup C, Rogge L, Huetz F, Peguillet I, Lantz O, Fontes M, Di Santo JP, Thomas S, Fellay J, Duffy D, Quintana-Murci L, Albert ML; Milieu Intérieur Consortium.

Nat Immunol. 2018 Mar;19(3):302-314. doi: 10.1038/s41590-018-0049-7. Epub 2018 Feb 23. Erratum in: Nat Immunol. 2018 May 3;:.

PMID:
29476184
13.

A Cross-Talk Between Microbiota-Derived Short-Chain Fatty Acids and the Host Mucosal Immune System Regulates Intestinal Homeostasis and Inflammatory Bowel Disease.

Gonçalves P, Araújo JR, Di Santo JP.

Inflamm Bowel Dis. 2018 Feb 15;24(3):558-572. doi: 10.1093/ibd/izx029.

PMID:
29462379
14.

Intrathymic Deletion of IL-7 Reveals a Contribution of the Bone Marrow to Thymic Rebound Induced by Androgen Blockade.

Rodrigues PM, Ribeiro AR, Serafini N, Meireles C, Di Santo JP, Alves NL.

J Immunol. 2018 Feb 15;200(4):1389-1398. doi: 10.4049/jimmunol.1701112. Epub 2018 Jan 10.

PMID:
29321277
15.

Replacing mouse BAFF with human BAFF does not improve B-cell maturation in hematopoietic humanized mice.

Lang J, Zhang B, Kelly M, Peterson JN, Barbee J, Freed BM, Di Santo JP, Matsuda JL, Torres RM, Pelanda R.

Blood Adv. 2017 Dec 19;1(27):2729-2741. doi: 10.1182/bloodadvances.2017010090. eCollection 2017 Dec 26.

16.

A functional DC cross talk promotes human ILC homeostasis in humanized mice.

Lopez-Lastra S, Masse-Ranson G, Fiquet O, Darche S, Serafini N, Li Y, Dusséaux M, Strick-Marchand H, Di Santo JP.

Blood Adv. 2017 Apr 6;1(10):601-614. doi: 10.1182/bloodadvances.2017004358. eCollection 2017 Apr 11.

17.

Humanized mouse models to study pathophysiology and treatment of HIV infection.

Masse-Ranson G, Mouquet H, Di Santo JP.

Curr Opin HIV AIDS. 2018 Mar;13(2):143-151. doi: 10.1097/COH.0000000000000440.

PMID:
29194124
18.

Regulatory T cells control toxicity in a humanized model of IL-2 therapy.

Li Y, Strick-Marchand H, Lim AI, Ren J, Masse-Ranson G, Dan Li, Jouvion G, Rogge L, Lucas S, Bin Li, Di Santo JP.

Nat Commun. 2017 Nov 24;8(1):1762. doi: 10.1038/s41467-017-01570-9.

19.

'ILC-poiesis': generating tissue ILCs from naïve precursors.

Di Santo JP, Lim AI, Yssel H.

Oncotarget. 2017 Sep 19;8(47):81729-81730. doi: 10.18632/oncotarget.21046. eCollection 2017 Oct 10. No abstract available.

20.

Animal models for viral diseases: Non-human primate and humanized mouse models for viral infections.

Di Santo JP, Apetrei C.

Curr Opin Virol. 2017 Aug;25:v-vii. doi: 10.1016/j.coviro.2017.09.001. No abstract available.

PMID:
28939290
21.

Lactobacillus paracasei feeding improves immune control of influenza infection in mice.

Belkacem N, Serafini N, Wheeler R, Derrien M, Boucinha L, Couesnon A, Cerf-Bensussan N, Gomperts Boneca I, Di Santo JP, Taha MK, Bourdet-Sicard R.

PLoS One. 2017 Sep 20;12(9):e0184976. doi: 10.1371/journal.pone.0184976. eCollection 2017.

22.

Viral Load Affects the Immune Response to HBV in Mice With Humanized Immune System and Liver.

Dusséaux M, Masse-Ranson G, Darche S, Ahodantin J, Li Y, Fiquet O, Beaumont E, Moreau P, Rivière L, Neuveut C, Soussan P, Roingeard P, Kremsdorf D, Di Santo JP, Strick-Marchand H.

Gastroenterology. 2017 Dec;153(6):1647-1661.e9. doi: 10.1053/j.gastro.2017.08.034. Epub 2017 Aug 26.

23.

Synergy between the Host Immune System and Bacteriophage Is Essential for Successful Phage Therapy against an Acute Respiratory Pathogen.

Roach DR, Leung CY, Henry M, Morello E, Singh D, Di Santo JP, Weitz JS, Debarbieux L.

Cell Host Microbe. 2017 Jul 12;22(1):38-47.e4. doi: 10.1016/j.chom.2017.06.018.

24.

Modeling Natural Killer Cell Targeted Immunotherapies.

Lopez-Lastra S, Di Santo JP.

Front Immunol. 2017 Mar 29;8:370. doi: 10.3389/fimmu.2017.00370. eCollection 2017. Review.

25.

Developmental options and functional plasticity of innate lymphoid cells.

Lim AI, Verrier T, Vosshenrich CA, Di Santo JP.

Curr Opin Immunol. 2017 Feb;44:61-68. doi: 10.1016/j.coi.2017.03.010. Epub 2017 Mar 28. Review.

PMID:
28359987
26.

Systemic Human ILC Precursors Provide a Substrate for Tissue ILC Differentiation.

Lim AI, Li Y, Lopez-Lastra S, Stadhouders R, Paul F, Casrouge A, Serafini N, Puel A, Bustamante J, Surace L, Masse-Ranson G, David E, Strick-Marchand H, Le Bourhis L, Cocchi R, Topazio D, Graziano P, Muscarella LA, Rogge L, Norel X, Sallenave JM, Allez M, Graf T, Hendriks RW, Casanova JL, Amit I, Yssel H, Di Santo JP.

Cell. 2017 Mar 9;168(6):1086-1100.e10. doi: 10.1016/j.cell.2017.02.021.

27.

In Vivo Efficacy of Umbilical Cord Blood Stem Cell-Derived NK Cells in the Treatment of Metastatic Colorectal Cancer.

Veluchamy JP, Lopez-Lastra S, Spanholtz J, Bohme F, Kok N, Heideman DA, Verheul HM, Di Santo JP, de Gruijl TD, van der Vliet HJ.

Front Immunol. 2017 Feb 6;8:87. doi: 10.3389/fimmu.2017.00087. eCollection 2017.

28.

Glomerular common gamma chain confers B- and T-cell-independent protection against glomerulonephritis.

Luque Y, Cathelin D, Vandermeersch S, Xu X, Sohier J, Placier S, Xu-Dubois YC, Louis K, Hertig A, Bories JC, Vasseur F, Campagne F, Di Santo JP, Vosshenrich C, Rondeau E, Mesnard L.

Kidney Int. 2017 May;91(5):1146-1158. doi: 10.1016/j.kint.2016.10.037. Epub 2017 Jan 19.

29.

Bacterial virulence factor inhibits caspase-4/11 activation in intestinal epithelial cells.

Pallett MA, Crepin VF, Serafini N, Habibzay M, Kotik O, Sanchez-Garrido J, Di Santo JP, Shenoy AR, Berger CN, Frankel G.

Mucosal Immunol. 2017 May;10(3):602-612. doi: 10.1038/mi.2016.77. Epub 2016 Sep 14.

30.

Interleukin-15-Dependent T-Cell-like Innate Intraepithelial Lymphocytes Develop in the Intestine and Transform into Lymphomas in Celiac Disease.

Ettersperger J, Montcuquet N, Malamut G, Guegan N, Lopez-Lastra S, Gayraud S, Reimann C, Vidal E, Cagnard N, Villarese P, Andre-Schmutz I, Gomes Domingues R, Godinho-Silva C, Veiga-Fernandes H, Lhermitte L, Asnafi V, Macintyre E, Cellier C, Beldjord K, Di Santo JP, Cerf-Bensussan N, Meresse B.

Immunity. 2016 Sep 20;45(3):610-625. doi: 10.1016/j.immuni.2016.07.018. Epub 2016 Sep 6.

31.

The Spectrum and Regulatory Landscape of Intestinal Innate Lymphoid Cells Are Shaped by the Microbiome.

Gury-BenAri M, Thaiss CA, Serafini N, Winter DR, Giladi A, Lara-Astiaso D, Levy M, Salame TM, Weiner A, David E, Shapiro H, Dori-Bachash M, Pevsner-Fischer M, Lorenzo-Vivas E, Keren-Shaul H, Paul F, Harmelin A, Eberl G, Itzkovitz S, Tanay A, Di Santo JP, Elinav E, Amit I.

Cell. 2016 Aug 25;166(5):1231-1246.e13. doi: 10.1016/j.cell.2016.07.043. Epub 2016 Aug 18.

32.

Phenotypic and Functional Plasticity of Murine Intestinal NKp46+ Group 3 Innate Lymphoid Cells.

Verrier T, Satoh-Takayama N, Serafini N, Marie S, Di Santo JP, Vosshenrich CA.

J Immunol. 2016 Jun 1;196(11):4731-8. doi: 10.4049/jimmunol.1502673. Epub 2016 Apr 22.

33.

Notch signaling in group 3 innate lymphoid cells modulates their plasticity.

Chea S, Perchet T, Petit M, Verrier T, Guy-Grand D, Banchi EG, Vosshenrich CA, Di Santo JP, Cumano A, Golub R.

Sci Signal. 2016 May 3;9(426):ra45. doi: 10.1126/scisignal.aaf2223.

34.

IL-12 drives functional plasticity of human group 2 innate lymphoid cells.

Lim AI, Menegatti S, Bustamante J, Le Bourhis L, Allez M, Rogge L, Casanova JL, Yssel H, Di Santo JP.

J Exp Med. 2016 Apr 4;213(4):569-83. doi: 10.1084/jem.20151750. Epub 2016 Mar 14.

35.

An Intestinal Inflammasome - The ILC3-Cytokine Tango.

Gonçalves P, Di Santo JP.

Trends Mol Med. 2016 Apr;22(4):269-271. doi: 10.1016/j.molmed.2016.02.008. Epub 2016 Mar 7.

PMID:
26965960
36.

A novel Flt3-deficient HIS mouse model with selective enhancement of human DC development.

Li Y, Mention JJ, Court N, Masse-Ranson G, Toubert A, Spits H, Legrand N, Corcuff E, Strick-Marchand H, Di Santo JP.

Eur J Immunol. 2016 May;46(5):1291-9. doi: 10.1002/eji.201546132. Epub 2016 Mar 1.

37.

Probing Human NK Cell Biology Using Human Immune System (HIS) Mice.

Li Y, Di Santo JP.

Curr Top Microbiol Immunol. 2016;395:191-208. doi: 10.1007/82_2015_488. Review.

PMID:
26459320
38.

IL-2 and IL-15 regulate CD8+ memory T-cell differentiation but are dispensable for protective recall responses.

Mathieu C, Beltra JC, Charpentier T, Bourbonnais S, Di Santo JP, Lamarre A, Decaluwe H.

Eur J Immunol. 2015 Dec;45(12):3324-38. doi: 10.1002/eji.201546000. Epub 2015 Nov 2.

39.

Transcriptional regulation of innate lymphoid cell fate.

Serafini N, Vosshenrich CA, Di Santo JP.

Nat Rev Immunol. 2015 Jul;15(7):415-28. doi: 10.1038/nri3855. Epub 2015 Jun 12. Review.

40.

Innate lymphoid cells. Innate lymphoid cells: a new paradigm in immunology.

Eberl G, Colonna M, Di Santo JP, McKenzie AN.

Science. 2015 May 22;348(6237):aaa6566. doi: 10.1126/science.aaa6566. Epub 2015 May 21. Review.

41.

NFIL3 orchestrates the emergence of common helper innate lymphoid cell precursors.

Xu W, Domingues RG, Fonseca-Pereira D, Ferreira M, Ribeiro H, Lopez-Lastra S, Motomura Y, Moreira-Santos L, Bihl F, Braud V, Kee B, Brady H, Coles MC, Vosshenrich C, Kubo M, Di Santo JP, Veiga-Fernandes H.

Cell Rep. 2015 Mar 31;10(12):2043-54. doi: 10.1016/j.celrep.2015.02.057. Epub 2015 Mar 19.

42.

A novel mouse model for stable engraftment of a human immune system and human hepatocytes.

Strick-Marchand H, Dusséaux M, Darche S, Huntington ND, Legrand N, Masse-Ranson G, Corcuff E, Ahodantin J, Weijer K, Spits H, Kremsdorf D, Di Santo JP.

PLoS One. 2015 Mar 17;10(3):e0119820. doi: 10.1371/journal.pone.0119820. eCollection 2015.

43.

Semi-automated and standardized cytometric procedures for multi-panel and multi-parametric whole blood immunophenotyping.

Hasan M, Beitz B, Rouilly V, Libri V, Urrutia A, Duffy D, Cassard L, Di Santo JP, Mottez E, Quintana-Murci L, Albert ML, Rogge L; Milieu Intérieur Consortium.

Clin Immunol. 2015 Apr;157(2):261-76. doi: 10.1016/j.clim.2014.12.008. Epub 2015 Jan 6.

44.

A novel immunoregulatory role for NK-cell cytotoxicity in protection from HLH-like immunopathology in mice.

Sepulveda FE, Maschalidi S, Vosshenrich CA, Garrigue A, Kurowska M, Ménasche G, Fischer A, Di Santo JP, de Saint Basile G.

Blood. 2015 Feb 26;125(9):1427-34. doi: 10.1182/blood-2014-09-602946. Epub 2014 Dec 18.

45.

The brave new world of innate lymphoid cells.

Eberl G, Di Santo JP, Vivier E.

Nat Immunol. 2015 Jan;16(1):1-5. doi: 10.1038/ni.3059. No abstract available.

PMID:
25521670
46.

The chemokine receptor CXCR6 controls the functional topography of interleukin-22 producing intestinal innate lymphoid cells.

Satoh-Takayama N, Serafini N, Verrier T, Rekiki A, Renauld JC, Frankel G, Di Santo JP.

Immunity. 2014 Nov 20;41(5):776-88. doi: 10.1016/j.immuni.2014.10.007. Epub 2014 Nov 6.

47.

Engineering attenuated virulence of a Theileria annulata-infected macrophage.

Echebli N, Mhadhbi M, Chaussepied M, Vayssettes C, Di Santo JP, Darghouth MA, Langsley G.

PLoS Negl Trop Dis. 2014 Nov 6;8(11):e3183. doi: 10.1371/journal.pntd.0003183. eCollection 2014.

48.

GATA-3 function in innate and adaptive immunity.

Tindemans I, Serafini N, Di Santo JP, Hendriks RW.

Immunity. 2014 Aug 21;41(2):191-206. doi: 10.1016/j.immuni.2014.06.006. Review.

49.

Conditional ablation of NKp46+ cells using a novel Ncr1(greenCre) mouse strain: NK cells are essential for protection against pulmonary B16 metastases.

Merzoug LB, Marie S, Satoh-Takayama N, Lesjean S, Albanesi M, Luche H, Fehling HJ, Di Santo JP, Vosshenrich CA.

Eur J Immunol. 2014 Nov;44(11):3380-91. doi: 10.1002/eji.201444643. Epub 2014 Sep 19.

50.

Staying innate: transcription factor maintenance of innate lymphoid cell identity.

Di Santo JP.

Immunol Rev. 2014 Sep;261(1):169-76. doi: 10.1111/imr.12202.

PMID:
25123284

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