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Spectroscopic Characterization of Bovine, Avian and Johnin Purified Protein Derivative (PPD) with High-Throughput Fourier Transform InfraRed-Based Method.

Corneli S, Corte L, Roscini L, Di Paolo A, Colabella C, Petrucci L, Severi G, Cagiola M, Mazzone P.

Pathogens. 2019 Aug 29;8(3). pii: E136. doi: 10.3390/pathogens8030136.


An NMR and MD study of complexes of bacteriophage lambda lysozyme with tetra- and hexa-N-acetylchitohexaose.

Turupcu A, Bowen AM, Di Paolo A, Matagne A, Oostenbrink C, Redfield C, Smith LJ.

Proteins. 2020 Jan;88(1):82-93. doi: 10.1002/prot.25770. Epub 2019 Jul 26.


The WNT Pathway Is Relevant for the BCR-ABL1-Independent Resistance in Chronic Myeloid Leukemia.

Grassi S, Palumbo S, Mariotti V, Liberati D, Guerrini F, Ciabatti E, Salehzadeh S, Baratè C, Balducci S, Ricci F, Buda G, Iovino L, Mazziotta F, Ghio F, Ercolano G, Di Paolo A, Cecchettini A, Baldini C, Mattii L, Pellegrini S, Petrini M, Galimberti S.

Front Oncol. 2019 Jun 24;9:532. doi: 10.3389/fonc.2019.00532. eCollection 2019.


Appropriateness of repetitive therapeutic drug monitoring and laboratory turnaround time.

Sarli V, Ciofi L, Lastella M, Muscatello B, Pisaturo F, Paolilli O, Luci G, Cucchiara F, Pellegrini G, Bocci G, Danesi R, Di Paolo A.

Clin Chem Lab Med. 2019 Nov 26;57(12):e331-e333. doi: 10.1515/cclm-2019-0429. No abstract available.


Nanowire Superinductance Fluxonium Qubit.

Hazard TM, Gyenis A, Di Paolo A, Asfaw AT, Lyon SA, Blais A, Houck AA.

Phys Rev Lett. 2019 Jan 11;122(1):010504. doi: 10.1103/PhysRevLett.122.010504.


Using a variant of coverslip hypoxia to visualize tumor cell alterations at increasing distances from an oxygen source.

Arocena M, Landeira M, Di Paolo A, Silva A, Sotelo-Silveira J, Fernández A, Alonso J.

J Cell Physiol. 2019 Aug;234(10):16671-16678. doi: 10.1002/jcp.28507. Epub 2019 Mar 25.


Different Underlying Mechanism Might Explain the Absence of a Significant Difference in Area Under the Concentration-Time Curve of Linezolid for Different ABCB1 Genotypes.

Allegra S, Di Paolo A, Cusato J, Fatiguso G, Arrigoni E, Danesi R, Corcione S, DʼAvolio A.

Ther Drug Monit. 2019 Apr;41(2):254-255. doi: 10.1097/FTD.0000000000000596. No abstract available.


A case report of a TDM-guided optimization of mitotane for a safe and effective long-term treatment.

Di Paolo A, Ciofi L, Bacca A, Bernini G.

J Chemother. 2019 Apr;31(2):105-108. doi: 10.1080/1120009X.2018.1552502. Epub 2019 Mar 4.


Total neoadjuvant approach with FOLFOXIRI plus bevacizumab followed by chemoradiotherapy plus bevacizumab in locally advanced rectal cancer: the TRUST trial.

Masi G, Vivaldi C, Fornaro L, Lonardi S, Buccianti P, Sainato A, Marcucci L, Martignetti A, Luca Urso ED, Castagna M, Fontanini G, Bergamo F, Musettini G, Urbani L, Sensi E, Balestri R, Montrone S, Pasqualetti F, Cremolini C, Di Paolo A, Zagonel V, Falcone A.

Eur J Cancer. 2019 Mar;110:32-41. doi: 10.1016/j.ejca.2019.01.006. Epub 2019 Feb 7.


Rebuttal letter: Different underlying mechanism might explain the absence of a significant difference in AUC of linezolid for different ABCB1 genotypes.

Allegra S, Di Paolo A, Cusato J, Fatiguso G, Arrigoni E, Danesi R, Corcione S, DʼAvolio A.

Ther Drug Monit. 2019 Jan 9. doi: 10.1097/FTD.0000000000000596. [Epub ahead of print] No abstract available.


Daptomycin Plasma and CSF Levels in Patients with Healthcare-Associated Meningitis.

Piva S, Di Paolo A, Galeotti L, Ceccherini F, Cordoni F, Signorini L, Togni T, De Nicolò A, Rasulo FA, Fagoni N, Latronico N, D'Avolio A.

Neurocrit Care. 2019 Aug;31(1):116-124. doi: 10.1007/s12028-018-0657-y.


The Polycomb BMI1 Protein Is Co-expressed With CD26+ in Leukemic Stem Cells of Chronic Myeloid Leukemia.

Galimberti S, Grassi S, Baratè C, Guerrini F, Ciabatti E, Perutelli F, Ricci F, Del Genio G, Montali M, Barachini S, Giuliani C, Ferreri MI, Valetto A, Abruzzese E, Ippolito C, Iurlo A, Bocchia M, Sicuranza A, Martino B, Iovino L, Buda G, Salehzadeh S, Petrini M, Di Paolo A, Mattii L.

Front Oncol. 2018 Dec 6;8:555. doi: 10.3389/fonc.2018.00555. eCollection 2018.


Doxycycline, an Inhibitor of Mitochondrial Biogenesis, Effectively Reduces Cancer Stem Cells (CSCs) in Early Breast Cancer Patients: A Clinical Pilot Study.

Scatena C, Roncella M, Di Paolo A, Aretini P, Menicagli M, Fanelli G, Marini C, Mazzanti CM, Ghilli M, Sotgia F, Lisanti MP, Naccarato AG.

Front Oncol. 2018 Oct 12;8:452. doi: 10.3389/fonc.2018.00452. eCollection 2018.


A Common mdr1 Gene Polymorphism is Associated With Changes in Linezolid Clearance.

Allegra S, Di Paolo A, Cusato J, Fatiguso G, Arrigoni E, Danesi R, Corcione S, DʼAvolio A.

Ther Drug Monit. 2018 Oct;40(5):602-609. doi: 10.1097/FTD.0000000000000536.


First evaluation of endotoxins in veterinary autogenous vaccines produced in Italy by LAL assay.

Di Paolo A, Forti K, Anzalone L, Corneli S, Pellegrini M, Severi G, Cagiola M.

Biologicals. 2018 Sep;55:71-73. doi: 10.1016/j.biologicals.2018.06.001. Epub 2018 Jun 21.


Validation of exhaled volatile organic compounds analysis using electronic nose as index of COPD severity.

Finamore P, Pedone C, Scarlata S, Di Paolo A, Grasso S, Santonico M, Pennazza G, Antonelli Incalzi R.

Int J Chron Obstruct Pulmon Dis. 2018 May 1;13:1441-1448. doi: 10.2147/COPD.S159684. eCollection 2018.


Survival of Mycobacterium avium subsp. paratuberculosis in the intermediate and final digestion products of biogas plants.

Mazzone P, Corneli S, Di Paolo A, Maresca C, Felici A, Biagetti M, Ciullo M, Sebastiani C, Pezzotti G, Leo S, Ricchi M, Arrigoni N.

J Appl Microbiol. 2018 Jul;125(1):36-44. doi: 10.1111/jam.13762. Epub 2018 Apr 16.


Lamellipodial wrinkles in fish keratocytes as markers of imperfect coordination between extension and retraction during cell migration.

Arocena M, Pérez Zerpa JM, Di Paolo A, Aguilera PA, Sotelo-Silveira J.

Biochem Biophys Res Commun. 2018 Apr 6;498(3):680-685. doi: 10.1016/j.bbrc.2018.03.045. Epub 2018 Mar 13.


Generic Substitution of Orphan Drugs for the Treatment of Rare Diseases: Exploring the Potential Challenges.

Di Paolo A, Arrigoni E.

Drugs. 2018 Mar;78(4):399-410. doi: 10.1007/s40265-018-0882-x. Review.


Early manifestation of arm-leg coordination during stepping on a surface in human neonates.

La Scaleia V, Ivanenko Y, Fabiano A, Sylos-Labini F, Cappellini G, Picone S, Paolillo P, Di Paolo A, Lacquaniti F.

Exp Brain Res. 2018 Apr;236(4):1105-1115. doi: 10.1007/s00221-018-5201-y. Epub 2018 Feb 13.


Concise Review: Chronic Myeloid Leukemia: Stem Cell Niche and Response to Pharmacologic Treatment.

Arrigoni E, Del Re M, Galimberti S, Restante G, Rofi E, Crucitta S, Baratè C, Petrini M, Danesi R, Di Paolo A.

Stem Cells Transl Med. 2018 Mar;7(3):305-314. doi: 10.1002/sctm.17-0175. Epub 2018 Feb 8. Review.


Concise Review: Resistance to Tyrosine Kinase Inhibitors in Non-Small Cell Lung Cancer: The Role of Cancer Stem Cells.

Del Re M, Arrigoni E, Restante G, Passaro A, Rofi E, Crucitta S, De Marinis F, Di Paolo A, Danesi R.

Stem Cells. 2018 May;36(5):633-640. doi: 10.1002/stem.2787. Epub 2018 Feb 5. Review.


Corrigendum: Foot Placement Characteristics and Plantar Pressure Distribution Patterns during Stepping on Ground in Neonates.

Sylos-Labini F, Magnani S, Cappellini G, La Scaleia V, Fabiano A, Picone S, Paolillo P, Di Paolo A, Lacquaniti F, Ivanenko Y.

Front Physiol. 2017 Nov 27;8:973. doi: 10.3389/fphys.2017.00973. eCollection 2017.


Unravelling the Carbohydrate-Binding Preferences of the Carbohydrate-Binding Modules of AMP-Activated Protein Kinase.

Mobbs JI, Di Paolo A, Metcalfe RD, Selig E, Stapleton DI, Griffin MDW, Gooley PR.

Chembiochem. 2018 Feb 2;19(3):229-238. doi: 10.1002/cbic.201700589. Epub 2018 Jan 9.


The hOCT1 and ABCB1 polymorphisms do not influence the pharmacodynamics of nilotinib in chronic myeloid leukemia.

Galimberti S, Bucelli C, Arrigoni E, Baratè C, Grassi S, Ricci F, Guerrini F, Ciabatti E, Fava C, D'Avolio A, Fontanelli G, Cambrin GR, Isidori A, Loscocco F, Caocci G, Greco M, Bocchia M, Aprile L, Gozzini A, Scappini B, Cattaneo D, Scortechini AR, La Nasa G, Bosi A, Leoni P, Danesi R, Saglio G, Visani G, Cortelezzi A, Petrini M, Iurlo A, Di Paolo A.

Oncotarget. 2017 Sep 30;8(50):88021-88033. doi: 10.18632/oncotarget.21406. eCollection 2017 Oct 20.


Foot Placement Characteristics and Plantar Pressure Distribution Patterns during Stepping on Ground in Neonates.

Sylos-Labini F, Magnani S, Cappellini G, La Scaleia V, Fabiano A, Picone S, Paolillo P, Di Paolo A, Lacquaniti F, Ivanenko Y.

Front Physiol. 2017 Oct 10;8:784. doi: 10.3389/fphys.2017.00784. eCollection 2017. Erratum in: Front Physiol. 2017 Nov 27;8:973.


Sunitinib in Metastatic Renal Cell Carcinoma: The Pharmacological Basis of the Alternative 2/1 Schedule.

Di Paolo A, Bracarda S, Arrigoni E, Danesi R.

Front Pharmacol. 2017 Aug 7;8:523. doi: 10.3389/fphar.2017.00523. eCollection 2017. No abstract available.


Personalized medicine in Europe: not yet personal enough?

Di Paolo A, Sarkozy F, Ryll B, Siebert U.

BMC Health Serv Res. 2017 Apr 19;17(1):289. doi: 10.1186/s12913-017-2205-4. Review.


Association of the hOCT1/ABCB1 genotype with efficacy and tolerability of imatinib in patients affected by chronic myeloid leukemia.

Galeotti L, Ceccherini F, Domingo D, Laurino M, Polillo M, Di Paolo A, Baratè C, Fava C, D'Avolio A, Cervetti G, Guerrini F, Fontanelli G, Ciabatti E, Grassi S, Arrigoni E, Danesi R, Petrini M, Cornolti F, Saglio G, Galimberti S.

Cancer Chemother Pharmacol. 2017 Apr;79(4):767-773. doi: 10.1007/s00280-017-3271-3. Epub 2017 Mar 13.


Nuclear Compartmentalization Contributes to Stage-Specific Gene Expression Control in Trypanosoma cruzi.

Pastro L, Smircich P, Di Paolo A, Becco L, Duhagon MA, Sotelo-Silveira J, Garat B.

Front Cell Dev Biol. 2017 Feb 13;5:8. doi: 10.3389/fcell.2017.00008. eCollection 2017.


Fungicidal activity and PK/PD of caspofungin as tools to guide antifungal therapy in a fluconazole-resistant C. parapsilosis candidemia.

Tascini C, Sozio E, Di Paolo A, Tintori G, Leonildi A, Bertolino G, Carmassi F, Tagliaferri E, Menichetti F, Barchiesi F.

J Chemother. 2017 Dec;29(6):376-379. doi: 10.1080/1120009X.2017.1289308. Epub 2017 Feb 15.


Pharmacogenetics and Metabolism from Science to Implementation in Clinical Practice: The Example of Dihydropyrimidine Dehydrogenase.

Del Re M, Restante G, Di Paolo A, Crucitta S, Rofi E, Danesi R.

Curr Pharm Des. 2017;23(14):2028-2034. doi: 10.2174/1381612823666170125155530. Review.


Detection of Echinococcus granulosus G3 in a Wild Boar ( Sus scrofa ) in Central Italy using PCR and Sequencing.

Di Paolo A, Piseddu T, Sebastianelli M, Manuali E, Corneli S, Paniccià M, Papa P, Viali S, Mazzone P.

J Wildl Dis. 2017 Apr;53(2):399-401. doi: 10.7589/2015-12-344. Epub 2017 Jan 24.


Simultaneous, But Not Consecutive, Combination With Folinate Salts Potentiates 5-Fluorouracil Antitumor Activity In Vitro and In Vivo.

Di Paolo A, Orlandi P, Di Desidero T, Danesi R, Bocci G.

Oncol Res. 2017 Aug 7;25(7):1129-1140. doi: 10.3727/096504017X14841698396900. Epub 2017 Jan 20.


Pharmacogenetic Foundations of Therapeutic Efficacy and Adverse Events of Statins.

Arrigoni E, Del Re M, Fidilio L, Fogli S, Danesi R, Di Paolo A.

Int J Mol Sci. 2017 Jan 6;18(1). pii: E104. doi: 10.3390/ijms18010104. Review.


Recent advances in epigenomics in NSCLC: real-time detection and therapeutic implications.

Di Paolo A, Del Re M, Petrini I, Altavilla G, Danesi R.

Epigenomics. 2016 Aug;8(8):1151-67. doi: 10.2217/epi.16.10. Epub 2016 Aug 1. Review.


ATP-binding cassette transmembrane transporters and their epigenetic control in cancer: an overview.

Arrigoni E, Galimberti S, Petrini M, Danesi R, Di Paolo A.

Expert Opin Drug Metab Toxicol. 2016 Dec;12(12):1419-1432. Epub 2016 Aug 3. Review.


Onset of action of budesonide/formoterol Spiromax(®) compared with budesonide/formoterol Turbuhaler(®) in patients with COPD.

Cazzola M, Ora J, Di Paolo A, Puxeddu E, Calzetta L, Rogliani P.

Pulm Pharmacol Ther. 2016 Aug;39:48-53. doi: 10.1016/j.pupt.2016.06.006. Epub 2016 Jun 22.


Population pharmacokinetics and probability of target attainment of meropenem in critically ill patients.

Mattioli F, Fucile C, Del Bono V, Marini V, Parisini A, Molin A, Zuccoli ML, Milano G, Danesi R, Marchese A, Polillo M, Viscoli C, Pelosi P, Martelli A, Di Paolo A.

Eur J Clin Pharmacol. 2016 Jul;72(7):839-48. doi: 10.1007/s00228-016-2053-x. Epub 2016 Apr 6.


First Case of Trichoderma longibrachiatum CIED (Cardiac Implantable Electronic Device)-Associated Endocarditis in a Non-immunocompromised Host: Biofilm Removal and Diagnostic Problems in the Light of the Current Literature.

Tascini C, Cardinali G, Barletta V, Di Paolo A, Leonildi A, Zucchelli G, Corte L, Colabella C, Roscini L, Consorte A, Pasticci MB, Menichetti F, Bongiorni MG.

Mycopathologia. 2016 Apr;181(3-4):297-303. doi: 10.1007/s11046-015-9961-7. Epub 2015 Nov 20. Review.


Pharmacogenetics of BCR/ABL Inhibitors in Chronic Myeloid Leukemia.

Polillo M, Galimberti S, Baratè C, Petrini M, Danesi R, Di Paolo A.

Int J Mol Sci. 2015 Sep 21;16(9):22811-29. doi: 10.3390/ijms160922811. Review.


Oral administration of gentamicin for prophylaxis of KPC-producing Klebsiella pneumoniae gut colonization in patients treated with a novel parenchymal-sparing liver surgery: the GEN Gut study.

Tascini C, Urbani L, Sbrana F, Forfori F, Licitra G, Leoni C, Balestri R, Rossi E, Fortunato S, Leonildi A, Puccini M, Di Paolo A, Ripoli A, Colombatto P, Menichetti F, Buccianti P.

Intensive Care Med. 2016 Jan;42(1):124-5. doi: 10.1007/s00134-015-4049-x. Epub 2015 Sep 21. No abstract available.


Comment on "High expression of CD39/ENTPD1 in malignant epithelial cells of human rectal adenocarcinoma".

Antonioli L, di Paolo A, Fornai M, Danesi R, Blandizzi C.

Tumour Biol. 2015 Sep;36(10):7397-8. doi: 10.1007/s13277-015-4030-x. Epub 2015 Sep 17. No abstract available.


Polycomb genes are associated with response to imatinib in chronic myeloid leukemia.

Crea F, Di Paolo A, Liu HH, Polillo M, Clermont PL, Guerrini F, Ciabatti E, Ricci F, Baratè C, Fontanelli G, Barsotti S, Morganti R, Danesi R, Wang Y, Petrini M, Galimberti S, Helgason CD.

Epigenomics. 2015 Aug;7(5):757-65. doi: 10.2217/epi.15.35. Epub 2015 Sep 7.


Methods: for studying pharmacogenetic profiles of combination chemotherapeutic drugs.

Di Paolo A, Polillo M, Lastella M, Bocci G, Del Re M, Danesi R.

Expert Opin Drug Metab Toxicol. 2015;11(8):1253-67. doi: 10.1517/17425255.2015.1053460. Epub 2015 Jun 3. Review.


Determinants of oligosaccharide specificity of the carbohydrate-binding modules of AMP-activated protein kinase.

Mobbs JI, Koay A, Di Paolo A, Bieri M, Petrie EJ, Gorman MA, Doughty L, Parker MW, Stapleton DI, Griffin MD, Gooley PR.

Biochem J. 2015 Jun 1;468(2):245-57. doi: 10.1042/BJ20150270.


Single institute experience on 108 consecutive cases of type II odontoid fractures: surgery versus conservative treatment.

Di Paolo A, Piccirilli M, Pescatori L, Santoro A, D'Elia A.

Turk Neurosurg. 2014;24(6):891-6. doi: 10.5137/1019-5149.JTN.9731-13.0.


Granular cell tumor of the neurohypophysis: a single-institution experience.

Piccirilli M, Maiola V, Salvati M, D'Elia A, Di Paolo A, Campagna D, Santoro A, Delfini R.

Tumori. 2014 Jul-Aug;100(4):160e-4e. doi: 10.1700/1636.17940. Review.


Reduced circulating B-lymphocytes and altered B-cell compartments in patients suffering from chronic myeloid leukaemia undergoing therapy with Imatinib.

Carulli G, Baratè C, Marini A, Ottaviano V, Cervetti G, Fontanelli G, Guerrini F, Arici R, Guerri V, Di Paolo A, Polillo M, Ferreri MI, Galimberti S, Petrini M.

Hematol Oncol. 2015 Dec;33(4):250-2. doi: 10.1002/hon.2156. Epub 2014 Sep 25. No abstract available.


Loss of BRCA1 impairs centromeric cohesion and triggers chromosomal instability.

Di Paolo A, Racca C, Calsou P, Larminat F.

FASEB J. 2014 Dec;28(12):5250-61. doi: 10.1096/fj.14-250266. Epub 2014 Sep 9.


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