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Items: 1 to 50 of 727

1.

Comments on Disruption of the gonadal endocannabinoid system in zebrafish exposed to diisononyl phthalate - Forner-Piquer et al. (2018)": rebuttal to Prosser CM.

Forner-Piquer I, Santangeli S, Maradonna F, Rabbito A, Piscitelli F, Habibi HR, di Marzo V, Carnevali O.

Environ Pollut. 2020 Feb 4:114028. doi: 10.1016/j.envpol.2020.114028. [Epub ahead of print] No abstract available.

PMID:
32085902
2.

Phytocannabinoids promote viability and functional adipogenesis of bone marrow-derived mesenchymal stem cells through different molecular targets.

Fellous T, Di Maio F, Kalkann H, Carannante B, Boccella S, Petrosino S, Maione S, Di Marzo V, Arturo Iannotti F.

Biochem Pharmacol. 2020 Feb 13:113859. doi: 10.1016/j.bcp.2020.113859. [Epub ahead of print]

3.

Protective effects of </i>N<i>-oleoylglycine in a mouse model of mild traumatic brain injury.

Piscitelli F, Guida F, Luongo L, Iannotti FA, Boccella S, Verde R, Lauritano A, Imperatore R, Smoum R, Cristino L, Lichtman AH, Parker LA, Mechoulam R, Maione S, Di Marzo V.

ACS Chem Neurosci. 2020 Feb 4. doi: 10.1021/acschemneuro.9b00633. [Epub ahead of print]

PMID:
32017529
4.

α2-Adrenoceptor agonist induces peripheral antinociception via the endocannabinoid system.

Romero TRL, Miranda E Castor MG, Parrella C, Piscitelli F, Di Marzo V, Duarte IDG.

Pharmacol Rep. 2020 Feb;72(1):96-103. doi: 10.1007/s43440-019-00053-6. Epub 2020 Jan 10.

PMID:
32016857
5.

Endocannabinoid hydrolysis inhibition unmasks that unsaturated fatty acids induce a robust biosynthesis of 2-arachidonoyl-glycerol and its congeners in human myeloid leukocytes.

Turcotte C, Archambault AS, Dumais É, Martin C, Blanchet MR, Bissonnette E, Ohashi N, Yamamoto K, Itoh T, Laviolette M, Veilleux A, Boulet LP, Di Marzo V, Flamand N.

FASEB J. 2020 Feb 3. doi: 10.1096/fj.201902916R. [Epub ahead of print]

PMID:
32012340
6.

Desensitization of transient receptor potential vanilloid type-1 (TRPV1) channel as promising therapy of irritable bowel syndrome: characterization of the action of palvanil in the mouse gastrointestinal tract.

Szymaszkiewicz A, Włodarczyk J, Wasilewski A, Di Marzo V, Storr M, Fichna J, Zielińska M.

Naunyn Schmiedebergs Arch Pharmacol. 2020 Jan 30. doi: 10.1007/s00210-020-01829-x. [Epub ahead of print]

PMID:
32002574
7.

Palmitoylethanolamide counteracts substance P-induced mast cell activation in vitro by stimulating diacylglycerol lipase activity.

Petrosino S, Schiano Moriello A, Verde R, Allarà M, Imperatore R, Ligresti A, Mahmoud AM, Peritore AF, Iannotti FA, Di Marzo V.

J Neuroinflammation. 2019 Dec 26;16(1):274. doi: 10.1186/s12974-019-1671-5.

8.

Rapid and Concomitant Gut Microbiota and Endocannabinoidome Response to Diet-Induced Obesity in Mice.

Lacroix S, Pechereau F, Leblanc N, Boubertakh B, Houde A, Martin C, Flamand N, Silvestri C, Raymond F, Di Marzo V, Veilleux A.

mSystems. 2019 Dec 17;4(6). pii: e00407-19. doi: 10.1128/mSystems.00407-19.

9.

Cannabinoids and the expanded endocannabinoid system in neurological disorders.

Cristino L, Bisogno T, Di Marzo V.

Nat Rev Neurol. 2020 Jan;16(1):9-29. doi: 10.1038/s41582-019-0284-z. Epub 2019 Dec 12. Review.

PMID:
31831863
10.

Life-long epigenetic programming of cortical architecture by maternal 'Western' diet during pregnancy.

Cinquina V, Calvigioni D, Farlik M, Halbritter F, Fife-Gernedl V, Shirran SL, Fuszard MA, Botting CH, Poullet P, Piscitelli F, Máté Z, Szabó G, Yanagawa Y, Kasper S, Di Marzo V, Mackie K, McBain CJ, Bock C, Keimpema E, Harkany T.

Mol Psychiatry. 2020 Jan;25(1):22-36. doi: 10.1038/s41380-019-0580-4. Epub 2019 Nov 18.

PMID:
31735910
11.

Acute naloxone-precipitated morphine withdrawal elicits nausea-like somatic behaviors in rats in a manner suppressed by N-oleoylglycine.

Rock EM, Ayoub SM, Limebeer CL, Gene A, Wills KL, DeVuono MV, Smoum R, Di Marzo V, Lichtman AH, Mechoulam R, Parker LA.

Psychopharmacology (Berl). 2020 Feb;237(2):375-384. doi: 10.1007/s00213-019-05373-2. Epub 2019 Nov 11.

PMID:
31712968
12.

Germ-free mice exhibit profound gut microbiota-dependent alterations of intestinal endocannabinoidome signaling.

Manca C, Boubertakh B, Leblanc N, Deschênes T, Lacroix S, Martin C, Houde A, Veilleux A, Flamand N, Muccioli GG, Raymond F, Cani PD, Di Marzo V, Silvestri C.

J Lipid Res. 2020 Jan;61(1):70-85. doi: 10.1194/jlr.RA119000424. Epub 2019 Nov 5.

PMID:
31690638
13.

The Expanded Endocannabinoid System/Endocannabinoidome as a Potential Target for Treating Diabetes Mellitus.

Veilleux A, Di Marzo V, Silvestri C.

Curr Diab Rep. 2019 Nov 4;19(11):117. doi: 10.1007/s11892-019-1248-9. Review.

PMID:
31686231
14.

Effects of Dietary Bisphenol A on the Reproductive Function of Gilthead Sea Bream (Sparus aurata) Testes.

Forner-Piquer I, Fakriadis I, Mylonas CC, Piscitelli F, Di Marzo V, Maradonna F, Calduch-Giner J, Pérez-Sánchez J, Carnevali O.

Int J Mol Sci. 2019 Oct 10;20(20). pii: E5003. doi: 10.3390/ijms20205003.

15.

Human leukocytes differentially express endocannabinoid-glycerol lipases and hydrolyze 2-arachidonoyl-glycerol and its metabolites from the 15-lipoxygenase and cyclooxygenase pathways.

Turcotte C, Dumais É, Archambault AS, Martin C, Blanchet MR, Bissonnette É, Boulet LP, Laviolette M, Di Marzo V, Flamand N.

J Leukoc Biol. 2019 Dec;106(6):1337-1347. doi: 10.1002/JLB.3A0919-049RRR. Epub 2019 Sep 26.

PMID:
31556464
16.

The non-euphoric phytocannabinoid cannabidivarin counteracts intestinal inflammation in mice and cytokine expression in biopsies from UC pediatric patients.

Pagano E, Romano B, Iannotti FA, Parisi OA, D'Armiento M, Pignatiello S, Coretti L, Lucafò M, Venneri T, Stocco G, Lembo F, Orlando P, Capasso R, Di Marzo V, Izzo AA, Borrelli F.

Pharmacol Res. 2019 Nov;149:104464. doi: 10.1016/j.phrs.2019.104464. Epub 2019 Sep 22.

PMID:
31553934
17.

Corrigendum to "Systemic administration of serotonin exacerbates abdominal pain and colitis via interaction with the endocannabinoid system" [Biochem. Pharmacol. 161 (2019) 37-51].

Salaga M, Binienda A, Piscitelli F, Mokrowiecka A, Cygankiewicz AI, Verde R, Malecka-Panas E, Kordek R, Krajewska WM, Di Marzo V, Fichna J.

Biochem Pharmacol. 2019 Nov;169:113636. doi: 10.1016/j.bcp.2019.113636. Epub 2019 Sep 14. No abstract available.

PMID:
31526940
18.

Summary of the International Conference on Onco-Nephrology: an emerging field in medicine.

Capasso A, Benigni A, Capitanio U, Danesh FR, Di Marzo V, Gesualdo L, Grandaliano G, Jaimes EA, Malyszko J, Perazella MA, Qian Q, Ronco P, Rosner MH, Trepiccione F, Viggiano D, Zoccali C, Capasso G; International Conference on Onco-Nephrology Participants.

Kidney Int. 2019 Sep;96(3):555-567. doi: 10.1016/j.kint.2019.04.043. Epub 2019 May 31.

19.

Lifestyle and Metabolic Syndrome: Contribution of the Endocannabinoidome.

Di Marzo V, Silvestri C.

Nutrients. 2019 Aug 20;11(8). pii: E1956. doi: 10.3390/nu11081956. Review.

20.

Altered Metabolism of Phospholipases, Diacylglycerols, Endocannabinoids, and N-Acylethanolamines in Patients with Mastocytosis.

Ferrara AL, Piscitelli F, Petraroli A, Parente R, Galdiero MR, Varricchi G, Marone G, Triggiani M, Di Marzo V, Loffredo S.

J Immunol Res. 2019 Jul 1;2019:5836476. doi: 10.1155/2019/5836476. eCollection 2019.

21.

Cannabidiol improves vocal learning-dependent recovery from, and reduces magnitude of deficits following, damage to a cortical-like brain region in a songbird pre-clinical animal model.

Alalawi A, Dodu JC, Woolley-Roberts M, Brodie J, Di Marzo V, Soderstrom K.

Neuropharmacology. 2019 Nov 1;158:107716. doi: 10.1016/j.neuropharm.2019.107716. Epub 2019 Jul 17.

PMID:
31325430
22.

Structure-activity relationships of thiazole and benzothiazole derivatives as selective cannabinoid CB2 agonists with in vivo anti-inflammatory properties.

Ghonim AE, Ligresti A, Rabbito A, Mahmoud AM, Di Marzo V, Osman NA, Abadi AH.

Eur J Med Chem. 2019 Oct 15;180:154-170. doi: 10.1016/j.ejmech.2019.07.002. Epub 2019 Jul 2.

PMID:
31302448
23.

Discovery of novel benzofuran-based compounds with neuroprotective and immunomodulatory properties for Alzheimer's disease treatment.

Montanari S, Mahmoud AM, Pruccoli L, Rabbito A, Naldi M, Petralla S, Moraleda I, Bartolini M, Monti B, Iriepa I, Belluti F, Gobbi S, Di Marzo V, Bisi A, Tarozzi A, Ligresti A, Rampa A.

Eur J Med Chem. 2019 Sep 15;178:243-258. doi: 10.1016/j.ejmech.2019.05.080. Epub 2019 May 31.

PMID:
31185414
24.

Cannabidivarin completely rescues cognitive deficits and delays neurological and motor defects in male Mecp2 mutant mice.

Zamberletti E, Gabaglio M, Piscitelli F, Brodie JS, Woolley-Roberts M, Barbiero I, Tramarin M, Binelli G, Landsberger N, Kilstrup-Nielsen C, Rubino T, Di Marzo V, Parolaro D.

J Psychopharmacol. 2019 Jul;33(7):894-907. doi: 10.1177/0269881119844184. Epub 2019 May 14.

25.

Orexin-A Prevents Lipopolysaccharide-Induced Neuroinflammation at the Level of the Intestinal Barrier.

Tunisi L, Forte N, Fernández-Rilo AC, Mavaro I, Capasso R, D'Angelo L, Milić N, Cristino L, Di Marzo V, Palomba L.

Front Endocrinol (Lausanne). 2019 Apr 10;10:219. doi: 10.3389/fendo.2019.00219. eCollection 2019.

26.

Oleoyl glycine: interference with the aversive effects of acute naloxone-precipitated MWD, but not morphine reward, in male Sprague-Dawley rats.

Petrie GN, Wills KL, Piscitelli F, Smoum R, Limebeer CL, Rock EM, Humphrey AE, Sheppard-Perkins M, Lichtman AH, Mechoulam R, Di Marzo V, Parker LA.

Psychopharmacology (Berl). 2019 Sep;236(9):2623-2633. doi: 10.1007/s00213-019-05237-9. Epub 2019 Apr 16.

PMID:
30993360
27.

Altered gut microbiota and endocannabinoid system tone in vitamin D deficiency-mediated chronic pain.

Guida F, Boccella S, Belardo C, Iannotta M, Piscitelli F, De Filippis F, Paino S, Ricciardi F, Siniscalco D, Marabese I, Luongo L, Ercolini D, Di Marzo V, Maione S.

Brain Behav Immun. 2019 Apr 3. pii: S0889-1591(18)31247-9. doi: 10.1016/j.bbi.2019.04.006. [Epub ahead of print]

28.

In Silico Identification and Experimental Validation of (-)-Muqubilin A, a Marine Norterpene Peroxide, as PPARα/γ-RXRα Agonist and RARα Positive Allosteric Modulator.

D'Aniello E, Iannotti FA, Falkenberg LG, Martella A, Gentile A, De Maio F, Ciavatta ML, Gavagnin M, Waxman JS, Di Marzo V, Amodeo P, Vitale RM.

Mar Drugs. 2019 Feb 12;17(2). pii: E110. doi: 10.3390/md17020110.

29.

Intestinal epithelial N-acylphosphatidylethanolamine phospholipase D links dietary fat to metabolic adaptations in obesity and steatosis.

Everard A, Plovier H, Rastelli M, Van Hul M, de Wouters d'Oplinter A, Geurts L, Druart C, Robine S, Delzenne NM, Muccioli GG, de Vos WM, Luquet S, Flamand N, Di Marzo V, Cani PD.

Nat Commun. 2019 Jan 28;10(1):457. doi: 10.1038/s41467-018-08051-7.

30.

Identification and characterization of phytocannabinoids as novel dual PPARα/γ agonists by a computational and in vitro experimental approach.

D'Aniello E, Fellous T, Iannotti FA, Gentile A, Allarà M, Balestrieri F, Gray R, Amodeo P, Vitale RM, Di Marzo V.

Biochim Biophys Acta Gen Subj. 2019 Mar;1863(3):586-597. doi: 10.1016/j.bbagen.2019.01.002. Epub 2019 Jan 3.

PMID:
30611848
31.

Systemic administration of serotonin exacerbates abdominal pain and colitis via interaction with the endocannabinoid system.

Salaga M, Binienda A, Piscitelli F, Mokrowiecka A, Cygankiewicz AI, Verde R, Malecka-Panas E, Kordek R, Krajewska WM, Di Marzo V, Fichna J.

Biochem Pharmacol. 2019 Mar;161:37-51. doi: 10.1016/j.bcp.2019.01.001. Epub 2019 Jan 3. Erratum in: Biochem Pharmacol. 2019 Nov;169:113636.

PMID:
30611738
32.

Effects of diisononyl phthalate (DiNP) on the endocannabinoid and reproductive systems of male gilthead sea bream (Sparus aurata) during the spawning season.

Forner-Piquer I, Mylonas CC, Fakriadis I, Papadaki M, Piscitelli F, Di Marzo V, Calduch-Giner J, Pérez-Sánchez J, Carnevali O.

Arch Toxicol. 2019 Mar;93(3):727-741. doi: 10.1007/s00204-018-2378-6. Epub 2019 Jan 2.

PMID:
30600365
33.

Peripubertal cannabidiol treatment rescues behavioral and neurochemical abnormalities in the MAM model of schizophrenia.

Stark T, Ruda-Kucerova J, Iannotti FA, D'Addario C, Di Marco R, Pekarik V, Drazanova E, Piscitelli F, Bari M, Babinska Z, Giurdanella G, Di Bartolomeo M, Salomone S, Sulcova A, Maccarrone M, Wotjak CT, Starcuk Z Jr, Drago F, Mechoulam R, Di Marzo V, Micale V.

Neuropharmacology. 2019 Mar 1;146:212-221. doi: 10.1016/j.neuropharm.2018.11.035. Epub 2018 Nov 26.

PMID:
30496751
34.

Fishing for Targets of Alien Metabolites: A Novel Peroxisome Proliferator-Activated Receptor (PPAR) Agonist from a Marine Pest.

Vitale RM, D'Aniello E, Gorbi S, Martella A, Silvestri C, Giuliani ME, Fellous T, Gentile A, Carbone M, Cutignano A, Grauso L, Magliozzi L, Polese G, D'Aniello B, Defranoux F, Felline S, Terlizzi A, Calignano A, Regoli F, Di Marzo V, Amodeo P, Mollo E.

Mar Drugs. 2018 Nov 3;16(11). pii: E431. doi: 10.3390/md16110431.

35.

Synthesis of novel 2-(1-adamantanylcarboxamido)thiophene derivatives. Selective cannabinoid type 2 (CB2) receptor agonists as potential agents for the treatment of skin inflammatory disease.

Mugnaini C, Rabbito A, Brizzi A, Palombi N, Petrosino S, Verde R, Di Marzo V, Ligresti A, Corelli F.

Eur J Med Chem. 2019 Jan 1;161:239-251. doi: 10.1016/j.ejmech.2018.09.070. Epub 2018 Oct 13.

PMID:
30359820
36.

Ultra-micronized palmitoylethanolamide rescues the cognitive decline-associated loss of neural plasticity in the neuropathic mouse entorhinal cortex-dentate gyrus pathway.

Boccella S, Cristiano C, Romano R, Iannotta M, Belardo C, Farina A, Guida F, Piscitelli F, Palazzo E, Mazzitelli M, Imperatore R, Tunisi L, de Novellis V, Cristino L, Di Marzo V, Calignano A, Maione S, Luongo L.

Neurobiol Dis. 2019 Jan;121:106-119. doi: 10.1016/j.nbd.2018.09.023. Epub 2018 Sep 25.

PMID:
30266286
37.

Genetic and pharmacological regulation of the endocannabinoid CB1 receptor in Duchenne muscular dystrophy.

Iannotti FA, Pagano E, Guardiola O, Adinolfi S, Saccone V, Consalvi S, Piscitelli F, Gazzerro E, Busetto G, Carrella D, Capasso R, Puri PL, Minchiotti G, Di Marzo V.

Nat Commun. 2018 Sep 27;9(1):3950. doi: 10.1038/s41467-018-06267-1.

38.

FAAH-Catalyzed C-C Bond Cleavage of a New Multitarget Analgesic Drug.

Ligresti A, Silvestri C, Vitale RM, Martos JL, Piscitelli F, Wang JW, Allarà M, Carling RW, Luongo L, Guida F, Illiano A, Amoresano A, Maione S, Amodeo P, Woodward DF, Di Marzo V, Marino G.

ACS Chem Neurosci. 2019 Jan 16;10(1):424-437. doi: 10.1021/acschemneuro.8b00315. Epub 2018 Oct 4.

PMID:
30226747
39.

Reversal of albuminuria by combined AM6545 and perindopril therapy in experimental diabetic nephropathy.

Barutta F, Bellini S, Mastrocola R, Gambino R, Piscitelli F, di Marzo V, Corbetta B, Vemuri VK, Makriyannis A, Annaratone L, Bruno G, Gruden G.

Br J Pharmacol. 2018 Dec;175(23):4371-4385. doi: 10.1111/bph.14495. Epub 2018 Nov 6.

40.

Elongation of the Hydrophobic Chain as a Molecular Switch: Discovery of Capsaicin Derivatives and Endogenous Lipids as Potent Transient Receptor Potential Vanilloid Channel 2 Antagonists.

Schiano Moriello A, López Chinarro S, Novo Fernández O, Eras J, Amodeo P, Canela-Garayoa R, Vitale RM, Di Marzo V, De Petrocellis L.

J Med Chem. 2018 Sep 27;61(18):8255-8281. doi: 10.1021/acs.jmedchem.8b00734. Epub 2018 Sep 14.

PMID:
30176215
41.

Δ9-tetrahydrocannabivarin impairs epithelial calcium transport through inhibition of TRPV5 and TRPV6.

Janssens A, Silvestri C, Martella A, Vanoevelen JM, Di Marzo V, Voets T.

Pharmacol Res. 2018 Oct;136:83-89. doi: 10.1016/j.phrs.2018.08.021. Epub 2018 Aug 28.

PMID:
30170189
42.

New approaches and challenges to targeting the endocannabinoid system.

Di Marzo V.

Nat Rev Drug Discov. 2018 Sep;17(9):623-639. doi: 10.1038/nrd.2018.115. Epub 2018 Aug 17. Review. Erratum in: Nat Rev Drug Discov. 2018 Aug 30;17(9):688.

PMID:
30116049
43.

Overlapping Distribution of Orexin and Endocannabinoid Receptors and Their Functional Interaction in the Brain of Adult Zebrafish.

Imperatore R, D'Angelo L, Safari O, Motlagh HA, Piscitelli F, de Girolamo P, Cristino L, Varricchio E, di Marzo V, Paolucci M.

Front Neuroanat. 2018 Jul 30;12:62. doi: 10.3389/fnana.2018.00062. eCollection 2018.

44.

Development of Potent Inhibitors of Fatty Acid Amide Hydrolase Useful for the Treatment of Neuropathic Pain.

Brindisi M, Borrelli G, Brogi S, Grillo A, Maramai S, Paolino M, Benedusi M, Pecorelli A, Valacchi G, Di Cesare Mannelli L, Ghelardini C, Allarà M, Ligresti A, Minetti P, Campiani G, di Marzo V, Butini S, Gemma S.

ChemMedChem. 2018 Oct 8;13(19):2090-2103. doi: 10.1002/cmdc.201800397. Epub 2018 Aug 30.

PMID:
30085402
45.

Effects of non-euphoric plant cannabinoids on muscle quality and performance of dystrophic mdx mice.

Iannotti FA, Pagano E, Moriello AS, Alvino FG, Sorrentino NC, D'Orsi L, Gazzerro E, Capasso R, De Leonibus E, De Petrocellis L, Di Marzo V.

Br J Pharmacol. 2019 May;176(10):1568-1584. doi: 10.1111/bph.14460. Epub 2018 Sep 9.

PMID:
30074247
46.

CB1 receptor activation induces intracellular Ca2+ mobilization and 2-arachidonoylglycerol release in rodent spinal cord astrocytes.

Hegyi Z, Oláh T, Kőszeghy Á, Piscitelli F, Holló K, Pál B, Csernoch L, Di Marzo V, Antal M.

Sci Rep. 2018 Jul 12;8(1):10562. doi: 10.1038/s41598-018-28763-6. Erratum in: Sci Rep. 2018 Sep 7;8(1):13715.

47.

Endocrine disruptors in the diet of male Sparus aurata: Modulation of the endocannabinoid system at the hepatic and central level by Di-isononyl phthalate and Bisphenol A.

Forner-Piquer I, Mylonas CC, Calduch-Giner J, Maradonna F, Gioacchini G, Allarà M, Piscitelli F, Di Marzo V, Pérez-Sánchez J, Carnevali O.

Environ Int. 2018 Oct;119:54-65. doi: 10.1016/j.envint.2018.06.011. Epub 2018 Jun 19.

PMID:
29933238
48.

Experimental ischemia/reperfusion model impairs endocannabinoid signaling and Na+/K+ ATPase expression and activity in kidney proximal tubule cells.

Sampaio LS, Iannotti FA, Veneziani L, Borelli-Tôrres RT, De Maio F, Piscitelli F, Reis RAM, Di Marzo V, Einicker-Lamas M.

Biochem Pharmacol. 2018 Aug;154:482-491. doi: 10.1016/j.bcp.2018.06.005. Epub 2018 Jun 8.

PMID:
29890144
49.

Disruption of the gonadal endocannabinoid system in zebrafish exposed to diisononyl phthalate.

Forner-Piquer I, Santangeli S, Maradonna F, Rabbito A, Piscitelli F, Habibi HR, Di Marzo V, Carnevali O.

Environ Pollut. 2018 Oct;241:1-8. doi: 10.1016/j.envpol.2018.05.007. Epub 2018 May 21.

PMID:
29793103
50.

Role of Bisphenol A on the Endocannabinoid System at central and peripheral levels: Effects on adult female zebrafish.

Forner-Piquer I, Santangeli S, Maradonna F, Verde R, Piscitelli F, di Marzo V, Habibi HR, Carnevali O.

Chemosphere. 2018 Aug;205:118-125. doi: 10.1016/j.chemosphere.2018.04.078. Epub 2018 Apr 14.

PMID:
29689525

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