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Items: 1 to 50 of 56

1.

LRRK2 activation in idiopathic Parkinson's disease.

Di Maio R, Hoffman EK, Rocha EM, Keeney MT, Sanders LH, De Miranda BR, Zharikov A, Van Laar A, Stepan AF, Lanz TA, Kofler JK, Burton EA, Alessi DR, Hastings TG, Greenamyre JT.

Sci Transl Med. 2018 Jul 25;10(451). pii: eaar5429. doi: 10.1126/scitranslmed.aar5429.

PMID:
30045977
2.

Generation of three-dimensional human neuronal cultures: application to modeling CNS viral infections.

D'Aiuto L, Naciri J, Radio N, Tekur S, Clayton D, Apodaca G, Di Maio R, Zhi Y, Dimitrion P, Piazza P, Demers M, Wood J, Chu C, Callio J, McClain L, Yolken R, McNulty J, Kinchington P, Bloom D, Nimgaonkar V.

Stem Cell Res Ther. 2018 May 11;9(1):134. doi: 10.1186/s13287-018-0881-6.

3.

3D geophysical imaging for site-specific characterization plan of an old landfill.

Di Maio R, Fais S, Ligas P, Piegari E, Raga R, Cossu R.

Waste Manag. 2018 Jun;76:629-642. doi: 10.1016/j.wasman.2018.03.004. Epub 2018 Mar 7.

PMID:
29523455
4.

Preferential modulation of the lateral habenula activity by serotonin-2A rather than -2C receptors: Electrophysiological and neuroanatomical evidence.

Delicata F, Bombardi C, Pierucci M, Di Maio R, De Deurwaerdère P, Di Giovanni G.

CNS Neurosci Ther. 2018 Aug;24(8):721-733. doi: 10.1111/cns.12830. Epub 2018 Feb 25.

PMID:
29479825
5.

α-Synuclein binds to TOM20 and inhibits mitochondrial protein import in Parkinson's disease.

Di Maio R, Barrett PJ, Hoffman EK, Barrett CW, Zharikov A, Borah A, Hu X, McCoy J, Chu CT, Burton EA, Hastings TG, Greenamyre JT.

Sci Transl Med. 2016 Jun 8;8(342):342ra78. doi: 10.1126/scitranslmed.aaf3634.

6.

Zn(2+) -induced Ca(2+) release via ryanodine receptors triggers calcineurin-dependent redistribution of cortical neuronal Kv2.1 K(+) channels.

Schulien AJ, Justice JA, Di Maio R, Wills ZP, Shah NH, Aizenman E.

J Physiol. 2016 May 15;594(10):2647-59. doi: 10.1113/JP272117.

7.

Dermatofibroma looks dermoscopically different on trunk versus extremities.

Brancaccio G, Nuzzo T, DI Maio R, Lallas A, Gambardella A, Lupoli A, Caccavale S, Alfano R, Tschandl P, Argenziano G.

G Ital Dermatol Venereol. 2017 Aug;152(4):333-337. doi: 10.23736/S0392-0488.16.05279-2. Epub 2015 Dec 23.

PMID:
26698275
8.

An investigation of thrust, depth and the impedance cardiogram as measures of cardiopulmonary resuscitation efficacy in a porcine model of cardiac arrest.

Howe A, O'Hare P, Crawford P, Delafont B, McAlister O, Di Maio R, Clutton E, Adgey J, McEneaney D.

Resuscitation. 2015 Nov;96:114-20. doi: 10.1016/j.resuscitation.2015.07.020. Epub 2015 Jul 31.

PMID:
26234892
9.

Large-scale generation of human iPSC-derived neural stem cells/early neural progenitor cells and their neuronal differentiation.

D'Aiuto L, Zhi Y, Kumar Das D, Wilcox MR, Johnson JW, McClain L, MacDonald ML, Di Maio R, Schurdak ME, Piazza P, Viggiano L, Sweet R, Kinchington PR, Bhattacharjee AG, Yolken R, Nimgaonkar VL.

Organogenesis. 2014;10(4):365-77. doi: 10.1080/15476278.2015.1011921. Erratum in: Organogenesis. 2015;11(2):93. Nimgaonka, Vishwajit L [Corrected to Nimgaonkar, Vishwajit L].

10.

Post-status epilepticus treatment with the cannabinoid agonist WIN 55,212-2 prevents chronic epileptic hippocampal damage in rats.

Di Maio R, Cannon JR, Greenamyre JT.

Neurobiol Dis. 2015 Jan;73:356-65. doi: 10.1016/j.nbd.2014.10.018. Epub 2014 Oct 30.

PMID:
25447228
11.

Behavioral, neurochemical, and pathologic alterations in bacterial artificial chromosome transgenic G2019S leucine-rich repeated kinase 2 rats.

Lee JW, Tapias V, Di Maio R, Greenamyre JT, Cannon JR.

Neurobiol Aging. 2015 Jan;36(1):505-18. doi: 10.1016/j.neurobiolaging.2014.07.011. Epub 2014 Jul 15.

12.

Radiation dermatitis, burns, and recall phenomena: Meaningful instances of immunocompromised district.

Ruocco E, Di Maio R, Caccavale S, Siano M, Lo Schiavo A.

Clin Dermatol. 2014 Sep-Oct;32(5):660-9. doi: 10.1016/j.clindermatol.2014.04.014.

PMID:
25160108
13.

Transient muscarinic and glutamatergic stimulation of neural stem cells triggers acute and persistent changes in differentiation.

Samarasinghe RA, Kanuparthi PS, Timothy Greenamyre J, DeFranco DB, Di Maio R.

Neurobiol Dis. 2014 Oct;70:252-61. doi: 10.1016/j.nbd.2014.06.020. Epub 2014 Jul 6.

14.

Neuronal mechanisms of epileptogenesis.

Di Maio R.

Front Cell Neurosci. 2014 Feb 21;8:29. doi: 10.3389/fncel.2014.00029. eCollection 2014. No abstract available.

15.

A support vector machine for predicting defibrillation outcomes from waveform metrics.

Howe A, Escalona OJ, Di Maio R, Massot B, Cromie NA, Darragh KM, Adgey J, McEneaney DJ.

Resuscitation. 2014 Mar;85(3):343-9. doi: 10.1016/j.resuscitation.2013.11.021. Epub 2013 Nov 28.

PMID:
24291591
16.

Novel quinoxaline 1,4-di-N-oxide derivatives as new potential antichagasic agents.

Torres E, Moreno-Viguri E, Galiano S, Devarapally G, Crawford PW, Azqueta A, Arbillaga L, Varela J, Birriel E, Di Maio R, Cerecetto H, González M, Aldana I, Monge A, Pérez-Silanes S.

Eur J Med Chem. 2013 Aug;66:324-34. doi: 10.1016/j.ejmech.2013.04.065. Epub 2013 May 30.

17.

5-HT2 receptors-mediated modulation of voltage-gated K+ channels and neurophysiopathological correlates.

D'Adamo MC, Servettini I, Guglielmi L, Di Matteo V, Di Maio R, Di Giovanni G, Pessia M.

Exp Brain Res. 2013 Oct;230(4):453-62. doi: 10.1007/s00221-013-3555-8. Epub 2013 May 24. Review.

PMID:
23702970
18.

Evaluating 5-nitrofurans as trypanocidal agents.

Bot C, Hall BS, Alvarez G, Di Maio R, González M, Cerecetto H, Wilkinson SR.

Antimicrob Agents Chemother. 2013 Apr;57(4):1638-47. doi: 10.1128/AAC.02046-12. Epub 2013 Jan 18.

19.

Human induced pluripotent stem cell-derived models to investigate human cytomegalovirus infection in neural cells.

D'Aiuto L, Di Maio R, Heath B, Raimondi G, Milosevic J, Watson AM, Bamne M, Parks WT, Yang L, Lin B, Miki T, Mich-Basso JD, Arav-Boger R, Sibille E, Sabunciyan S, Yolken R, Nimgaonkar V.

PLoS One. 2012;7(11):e49700. doi: 10.1371/journal.pone.0049700. Epub 2012 Nov 27. Erratum in: PLoS One. 2014;9(1). doi:10.1371/annotation/ea66e8f1-9f80-422f-8836-308a4cdc8ae4.

20.

DJ-1 expression modulates astrocyte-mediated protection against neuronal oxidative stress.

Mullett SJ, Di Maio R, Greenamyre JT, Hinkle DA.

J Mol Neurosci. 2013 Mar;49(3):507-11. doi: 10.1007/s12031-012-9904-4. Epub 2012 Oct 15.

21.

Thiol oxidation and altered NR2B/NMDA receptor functions in in vitro and in vivo pilocarpine models: implications for epileptogenesis.

Di Maio R, Mastroberardino PG, Hu X, Montero LM, Greenamyre JT.

Neurobiol Dis. 2013 Jan;49:87-98. doi: 10.1016/j.nbd.2012.07.013. Epub 2012 Jul 21.

PMID:
22824136
22.

A sporadic case of oligosymptomatic ectrodactyly-ectodermal dysplasia-clefting syndrome.

Baroni A, Piccolo V, Di Maio R, Russo T.

Indian J Dermatol Venereol Leprol. 2012 Jul-Aug;78(4):521. doi: 10.4103/0378-6323.98102. No abstract available. Erratum in: Indian J Dermatol Venereol Leprol. 2012 Nov-Dec;78(6):773. Adone, Baroni [corrected to Baroni, Adone]; Vincenzo, Piccolo [corrected to Piccolo, Vincenzo]; Rosa, Di Maio [corrected to Di Maio, Rosa]; Teresa, Russo [corrected to Russo, Teresa].

23.

A low tilt waveform in the transthoracic defibrillation of ventricular arrhythmias during cardiac arrest.

Darragh KM, Manoharan G, Di Maio R, Stevenson M, Bennett JR, Walsh SJ, Allen JD, Anderson JM, Adgey AA.

Resuscitation. 2012 Dec;83(12):1438-43. doi: 10.1016/j.resuscitation.2012.04.018. Epub 2012 May 9.

PMID:
22579679
24.

Redox sensitivity of tyrosine hydroxylase activity and expression in dopaminergic dysfunction.

Di Giovanni G, Pessia M, Di Maio R.

CNS Neurol Disord Drug Targets. 2012 Jun 1;11(4):419-29. Review.

PMID:
22483306
25.

Nongenomic glucocorticoid receptor action regulates gap junction intercellular communication and neural progenitor cell proliferation.

Samarasinghe RA, Di Maio R, Volonte D, Galbiati F, Lewis M, Romero G, DeFranco DB.

Proc Natl Acad Sci U S A. 2011 Oct 4;108(40):16657-62. doi: 10.1073/pnas.1102821108. Epub 2011 Sep 19.

26.

Mal de Meleda with hyperpigmented spots.

Baroni A, Piccolo V, Di Maio R, Romano F, Di Girolamo F, Satriano RA.

Eur J Dermatol. 2011 May-Jun;21(3):459-60. doi: 10.1684/ejd.2010.1217. No abstract available.

PMID:
21546336
27.

3-Trifluoromethylquinoxaline N,N'-dioxides as anti-trypanosomatid agents. Identification of optimal anti-T. cruzi agents and mechanism of action studies.

Benitez D, Cabrera M, Hernández P, Boiani L, Lavaggi ML, Di Maio R, Yaluff G, Serna E, Torres S, Ferreira ME, Vera de Bilbao N, Torres E, Pérez-Silanes S, Solano B, Moreno E, Aldana I, López de Ceráin A, Cerecetto H, González M, Monge A.

J Med Chem. 2011 May 26;54(10):3624-36. doi: 10.1021/jm2002469. Epub 2011 May 4.

PMID:
21506600
28.

Mouse ES cells overexpressing DNMT1 produce abnormal neurons with upregulated NMDA/NR1 subunit.

D'Aiuto L, Di Maio R, Mohan KN, Minervini C, Saporiti F, Soreca I, Greenamyre JT, Chaillet JR.

Differentiation. 2011 Jul;82(1):9-17. doi: 10.1016/j.diff.2011.03.003. Epub 2011 Apr 13.

29.

Pilocapine alters NMDA receptor expression and function in hippocampal neurons: NADPH oxidase and ERK1/2 mechanisms.

Di Maio R, Mastroberardino PG, Hu X, Montero L, Greenamyre JT.

Neurobiol Dis. 2011 Jun;42(3):482-95. doi: 10.1016/j.nbd.2011.02.012. Epub 2011 Mar 17.

PMID:
21397025
30.

Single-cell redox imaging demonstrates a distinctive response of dopaminergic neurons to oxidative insults.

Horowitz MP, Milanese C, Di Maio R, Hu X, Montero LM, Sanders LH, Tapias V, Sepe S, van Cappellen WA, Burton EA, Greenamyre JT, Mastroberardino PG.

Antioxid Redox Signal. 2011 Aug 15;15(4):855-71. doi: 10.1089/ars.2010.3629. Epub 2011 Jun 6.

31.

Massive screening yields novel and selective Trypanosoma cruzi triosephosphate isomerase dimer-interface-irreversible inhibitors with anti-trypanosomal activity.

Alvarez G, Aguirre-López B, Varela J, Cabrera M, Merlino A, López GV, Lavaggi ML, Porcal W, Di Maio R, González M, Cerecetto H, Cabrera N, Pérez-Montfort R, de Gómez-Puyou MT, Gómez-Puyou A.

Eur J Med Chem. 2010 Dec;45(12):5767-72. doi: 10.1016/j.ejmech.2010.09.034. Epub 2010 Sep 19.

PMID:
20889239
32.

Papillomatosis cutis arising on an immuno-compromised district due to paraplegia.

Baroni A, Ruocco V, Di Maio R, Nuzzo T, Del Vecchio M, Ruocco E.

Br J Dermatol. 2010 Sep;163(3):646-8. doi: 10.1111/j.1365-2133.2010.09833.x. Epub 2010 Apr 29. No abstract available.

PMID:
20456343
33.

Cyclopentenone prostaglandin-induced unfolding and aggregation of the Parkinson disease-associated UCH-L1.

Koharudin LM, Liu H, Di Maio R, Kodali RB, Graham SH, Gronenborn AM.

Proc Natl Acad Sci U S A. 2010 Apr 13;107(15):6835-40. doi: 10.1073/pnas.1002295107. Epub 2010 Mar 15.

34.

Changes in the frequency spectrum, the P-P interval, and the bispectral index during ventricular fibrillation are physiologic indicators of ventricular fibrillation duration.

Di Maio R, Allen JD, Navarro C, Darragh K, Anderson JM, Adgey AA.

J Electrocardiol. 2009 Nov-Dec;42(6):527-33. doi: 10.1016/j.jelectrocard.2009.06.010. Epub 2009 Jul 23.

PMID:
19631334
35.

5-Nitro-2-furyl derivative actives against Trypanosoma cruzi: preliminary in vivo studies.

Cabrera E, Murguiondo MG, Arias MG, Arredondo C, Pintos C, Aguirre G, Fernández M, Basmadjián Y, Rosa R, Pacheco JP, Raymondo S, Di Maio R, González M, Cerecetto H.

Eur J Med Chem. 2009 Oct;44(10):3909-14. doi: 10.1016/j.ejmech.2009.04.015. Epub 2009 Apr 14.

PMID:
19446929
36.

Papillomatosis cutis lymphostatica.

Vozza A, Palla M, Aiello FS, Romano F, Di Maio R, Satriano RA, Nicoletti GF.

G Ital Dermatol Venereol. 2009 Apr;144(2):211-2. No abstract available.

PMID:
19357629
37.

Finite driving rate and anisotropy effects in landslide modeling.

Piegari E, Cataudella V, Di Maio R, Milano L, Nicodemi M.

Phys Rev E Stat Nonlin Soft Matter Phys. 2006 Feb;73(2 Pt 2):026123. Epub 2006 Feb 21.

PMID:
16605414
38.

New potent 5-nitrofuryl derivatives as inhibitors of Trypanosoma cruzi growth. 3D-QSAR (CoMFA) studies.

Aguirre G, Boiani M, Cabrera E, Cerecetto H, Di Maio R, González M, Denicola A, Sant'anna CM, Barreiro EJ.

Eur J Med Chem. 2006 Apr;41(4):457-66. Epub 2006 Feb 23.

PMID:
16497414
39.

New potent 5-substituted benzofuroxans as inhibitors of Trypanosoma cruzi growth: quantitative structure-activity relationship studies.

Aguirre G, Boiani L, Boiani M, Cerecetto H, Di Maio R, González M, Porcal W, Denicola A, Piro OE, Castellano EE, Sant'Anna CM, Barreiro EJ.

Bioorg Med Chem. 2005 Dec 1;13(23):6336-46. Epub 2005 Oct 3.

PMID:
16202608
40.

Benzo[1,2-c]1,2,5-oxadiazole N-oxide derivatives as potential antitrypanosomal drugs. Part 3: Substituents-clustering methodology in the search for new active compounds.

Aguirre G, Boiani L, Cerecetto H, Di Maio R, González M, Porcal W, Denicola A, Möller M, Thomson L, Tórtora V.

Bioorg Med Chem. 2005 Dec 1;13(23):6324-35. Epub 2005 Aug 22.

PMID:
16115774
41.

Quinoxaline N,N'-dioxide derivatives and related compounds as growth inhibitors of Trypanosoma cruzi. Structure-activity relationships.

Aguirre G, Cerecetto H, Di Maio R, González M, Alfaro ME, Jaso A, Zarranz B, Ortega MA, Aldana I, Monge-Vega A.

Bioorg Med Chem Lett. 2004 Jul 16;14(14):3835-9.

PMID:
15203172
42.

Design, synthesis and biological evaluation of new potent 5-nitrofuryl derivatives as anti-Trypanosoma cruzi agents. Studies of trypanothione binding site of trypanothione reductase as target for rational design.

Aguirre G, Cabrera E, Cerecetto H, Di Maio R, González M, Seoane G, Duffaut A, Denicola A, Gil MJ, Martínez-Merino V.

Eur J Med Chem. 2004 May;39(5):421-31.

PMID:
15110968
43.

ESR spin trapping studies of free radicals generated from nitrofuran derivative analogues of nifurtimox by electrochemical and Trypanosoma cruzi reduction.

Olea-Azar C, Rigol C, Mendizabal F, Morello A, Maya JD, Moncada C, Cabrera E, Di Maio R, González M, Cerecetto H.

Free Radic Res. 2003 Sep;37(9):993-1001.

PMID:
14670007
44.

CCK-nitric oxide interaction in rat cortex, striatum and pallidum.

Ferraro G, Sardo P, Di Giovanni G, Di Maio R, La Grutta V.

Comp Biochem Physiol C Toxicol Pharmacol. 2003 Aug;135(4):425-33.

PMID:
12965187
45.

Electrochemical and microsomal production of free radicals from 1,2,5-oxadiazole N-oxide as potential antiprotozoal drugs.

Olea-Azar C, Rigol C, Mendizábal F, Briones R, Cerecetto H, Di Maio R, Risso M, González M, Porcal W.

Spectrochim Acta A Mol Biomol Spectrosc. 2003 Jan 1;59(1):69-74.

PMID:
12509148
46.

ESR Spin Trapping Studies of Free Radicals Generated from Nitrofuran Derivative Analogues of Nifurtimox by Electrochemical and Trypanosoma cruzi Reduction.

Olea-Azar C, Rigol C, Mendizabal F, Morello A, Diego Maya J, Moncada C, Cabrera E, di Maio R, González M, Cerecetto H.

Free Radic Res. 2003;37(9):993-1001. doi: 10.1080/10715760310001598141.

PMID:
28447529
47.

Benzo[1,2-c]1,2,5-oxadiazole N-oxide derivatives as potential antitrypanosomal drugs. Structure-activity relationships. Part II.

Aguirre G, Cerecetto H, Di Maio R, González M, Porcal W, Seoane G, Ortega MA, Aldana I, Monge A, Denicola A.

Arch Pharm (Weinheim). 2002 Jan;335(1):15-21.

PMID:
11933675
48.

New thiadiazine derivatives with activity against Trypanosoma cruzi amastigotes.

Muelas S, Di Maio R, Cerecetto H, Seoane G, Ochoa C, Escario JA, Gómez-Barrio A.

Folia Parasitol (Praha). 2001;48(2):105-8.

49.

Neurotransmitters adenosine triphosphate and noradrenaline induce nitric oxide release in rat vas deferens.

Vetri T, Di Maio R, Bonafede G, Passafiume L, Postorino A.

J Auton Pharmacol. 2000 Jun;20(3):133-7.

PMID:
11193001
50.

Synthesis and herbicidal activity of N-oxide derivatives.

Cerecetto H, Dias E, Di Maio R, González M, Pacce S, Saenz P, Seoane G, Suescun L, Mombrú A, Fernández G, Lema M, Villalba J.

J Agric Food Chem. 2000 Jul;48(7):2995-3002.

PMID:
10898655

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