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Items: 15


Strengthening of the Efferent Olivocochlear System Leads to Synaptic Dysfunction and Tonotopy Disruption of a Central Auditory Nucleus.

Di Guilmi MN, Boero LE, Castagna VC, Rodríguez-Contreras A, Wedemeyer C, Gómez-Casati ME, Elgoyhen AB.

J Neurosci. 2019 Sep 4;39(36):7037-7048. doi: 10.1523/JNEUROSCI.2536-18.2019. Epub 2019 Jun 19.


Enhancement of the Medial Olivocochlear System Prevents Hidden Hearing Loss.

Boero LE, Castagna VC, Di Guilmi MN, Goutman JD, Elgoyhen AB, Gómez-Casati ME.

J Neurosci. 2018 Aug 22;38(34):7440-7451. doi: 10.1523/JNEUROSCI.0363-18.2018. Epub 2018 Jul 20.


A Gain-of-Function Mutation in the α9 Nicotinic Acetylcholine Receptor Alters Medial Olivocochlear Efferent Short-Term Synaptic Plasticity.

Wedemeyer C, Vattino LG, Moglie MJ, Ballestero J, Maison SF, Di Guilmi MN, Taranda J, Liberman MC, Fuchs PA, Katz E, Elgoyhen AB.

J Neurosci. 2018 Apr 18;38(16):3939-3954. doi: 10.1523/JNEUROSCI.2528-17.2018. Epub 2018 Mar 23.


Deletion of dopamine D2 receptors from parvalbumin interneurons in mouse causes schizophrenia-like phenotypes.

Tomasella E, Bechelli L, Ogando MB, Mininni C, Di Guilmi MN, De Fino F, Zanutto S, Elgoyhen AB, Marin-Burgin A, Gelman DM.

Proc Natl Acad Sci U S A. 2018 Mar 27;115(13):3476-3481. doi: 10.1073/pnas.1719897115. Epub 2018 Mar 12.


Acid-Sensing Ion Channels Activated by Evoked Released Protons Modulate Synaptic Transmission at the Mouse Calyx of Held Synapse.

González-Inchauspe C, Urbano FJ, Di Guilmi MN, Uchitel OD.

J Neurosci. 2017 Mar 8;37(10):2589-2599. doi: 10.1523/JNEUROSCI.2566-16.2017. Epub 2017 Feb 3.


Familial hemiplegic migraine type-1 mutated cav2.1 calcium channels alter inhibitory and excitatory synaptic transmission in the lateral superior olive of mice.

Inchauspe CG, Pilati N, Di Guilmi MN, Urbano FJ, Ferrari MD, van den Maagdenberg AM, Forsythe ID, Uchitel OD.

Hear Res. 2015 Jan;319:56-68. doi: 10.1016/j.heares.2014.11.006. Epub 2014 Dec 4.


Synaptic gain-of-function effects of mutant Cav2.1 channels in a mouse model of familial hemiplegic migraine are due to increased basal [Ca2+]i.

Di Guilmi MN, Wang T, Inchauspe CG, Forsythe ID, Ferrari MD, van den Maagdenberg AM, Borst JG, Uchitel OD.

J Neurosci. 2014 May 21;34(21):7047-58. doi: 10.1523/JNEUROSCI.2526-13.2014.


Calcium channels and synaptic transmission in familial hemiplegic migraine type 1 animal models.

Uchitel OD, González Inchauspe C, Di Guilmi MN.

Biophys Rev. 2014 Mar;6(1):15-26. doi: 10.1007/s12551-013-0126-y. Epub 2013 Dec 3. Review.


Acute effects of pregabalin on the function and cellular distribution of Ca(V)2.1 in HEK293t cells.

Weissmann C, Di Guilmi MN, Urbano FJ, Uchitel OD.

Brain Res Bull. 2013 Jan;90:107-13. doi: 10.1016/j.brainresbull.2012.10.001. Epub 2012 Oct 9.


Presynaptic CaV2.1 calcium channels carrying familial hemiplegic migraine mutation R192Q allow faster recovery from synaptic depression in mouse calyx of Held.

Inchauspe CG, Urbano FJ, Di Guilmi MN, Ferrari MD, van den Maagdenberg AM, Forsythe ID, Uchitel OD.

J Neurophysiol. 2012 Dec;108(11):2967-76. doi: 10.1152/jn.01183.2011. Epub 2012 Sep 5.


CaV2.1 voltage activated calcium channels and synaptic transmission in familial hemiplegic migraine pathogenesis.

Uchitel OD, Inchauspe CG, Urbano FJ, Di Guilmi MN.

J Physiol Paris. 2012 Jan;106(1-2):12-22. doi: 10.1016/j.jphysparis.2011.10.004. Epub 2011 Nov 2. Review.


P/Q-type calcium channel ablation in a mice glycinergic synapse mediated by multiple types of Ca²+ channels alters transmitter release and short term plasticity.

Giugovaz-Tropper B, González-Inchauspe C, Di Guilmi MN, Urbano FJ, Forsythe ID, Uchitel OD.

Neuroscience. 2011 Sep 29;192:219-30. doi: 10.1016/j.neuroscience.2011.06.021. Epub 2011 Jun 14.


Pregabalin modulation of neurotransmitter release is mediated by change in intrinsic activation/inactivation properties of ca(v)2.1 calcium channels.

Di Guilmi MN, Urbano FJ, Inchauspe CG, Uchitel OD.

J Pharmacol Exp Ther. 2011 Mar;336(3):973-82. doi: 10.1124/jpet.110.172171. Epub 2010 Dec 22.


Acute modulation of calcium currents and synaptic transmission by gabapentinoids.

Uchitel OD, Di Guilmi MN, Urbano FJ, Gonzalez-Inchauspe C.

Channels (Austin). 2010 Nov-Dec;4(6):490-6. Epub 2010 Nov 1. Review.


Gain of function in FHM-1 Cav2.1 knock-in mice is related to the shape of the action potential.

Inchauspe CG, Urbano FJ, Di Guilmi MN, Forsythe ID, Ferrari MD, van den Maagdenberg AM, Uchitel OD.

J Neurophysiol. 2010 Jul;104(1):291-9. doi: 10.1152/jn.00034.2010. Epub 2010 May 19.

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